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NDUFAF3 Gene

protein-coding   GIFtS: 53
GCID: GC03P049057

NADH Dehydrogenase (Ubiquinone) Complex I, Assembly Factor...

(Previous names: chromosome 3 open reading frame 60, NADH dehydrogenase (ubiquinone)...)
(Previous symbol: C3orf60)
  See NDUFAF3-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
NADH Dehydrogenase (Ubiquinone) Complex I, Assembly Factor 31 2     2P12
C3orf601 2 3     E3-32
NADH Dehydrogenase (Ubiquinone) 1 Alpha Subcomplex, Assembly Factor 31 2     NADH Dehydrogenase [Ubiquinone] 1 Alpha Subcomplex Assembly Factor 32
Chromosome 3 Open Reading Frame 601     Nuclear Protein E3-32

External Ids:    HGNC: 299181   Entrez Gene: 259152   Ensembl: ENSG000001780577   OMIM: 6129115   UniProtKB: Q9BU613   

Export aliases for NDUFAF3 gene to outside databases

Previous GC identifer: GC03P049034


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for NDUFAF3 Gene:
This gene encodes a mitochondrial complex I assembly protein that interacts with complex I subunits. Mutations in
this gene cause mitochondrial complex I deficiency, a fatal neonatal disorder of the oxidative phosphorylation
system. Alternatively spliced transcript variants encoding different isoforms have been identified. (provided by
RefSeq, Jul 2009)

GeneCards Summary for NDUFAF3 Gene:
NDUFAF3 (NADH dehydrogenase (ubiquinone) complex I, assembly factor 3) is a protein-coding gene. Diseases associated with NDUFAF3 include mitochondrial complex i deficiency.

UniProtKB/Swiss-Prot: NDUF3_HUMAN, Q9BU61
Function: Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I)

Gene Wiki entry for NDUFAF3 (C3orf60) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000003.11  NC_018914.2  NT_022517.19  
Regulatory elements:
   Regulatory transcription factor binding sites in the NDUFAF3 gene promoter:
         E2F-1   E2F   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNDUFAF3 promoter sequence
   Search Chromatin IP Primers for NDUFAF3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NDUFAF3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p21.31   Ensembl cytogenetic band:  3p21.31   HGNC cytogenetic band: 3p21.31

NDUFAF3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NDUFAF3 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P049057:  view genomic region     (about GC identifiers)

Start:
49,057,892 bp from pter      End:
49,060,928 bp from pter
Size:
3,037 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: NDUF3_HUMAN, Q9BU61 (See protein sequence)
Recommended Name: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3  
Size: 184 amino acids; 20350 Da
Subunit: Interacts with NDUFAF4, NDUFS2 and NDUFS3
Alternative splicing: 2 isoforms:  Q9BU61-1   Q9BU61-2   

Explore the universe of human proteins at neXtProt for NDUFAF3: NX_Q9BU61

Explore proteomics data for NDUFAF3 at MOPED


See NDUFAF3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (4 alternative transcripts): 
NP_951032.1  NP_951033.1  NP_951047.1  NP_951056.1  

ENSEMBL proteins: 
 ENSP00000323003   ENSP00000323076   ENSP00000378843   ENSP00000402465  

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
MITOAF: Mitochondrial respiratory chain complex assembly factors

1 InterPro protein domain:
 IPR007523 NADH_Ub_cplx-1_asu_assmbl-fac3

Graphical View of Domain Structure for InterPro Entry Q9BU61

ProtoNet protein and cluster: Q9BU61


Find genes that share domains with NDUFAF3           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: NDUF3_HUMAN, Q9BU61
Function: Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I)

     Gene Ontology (GO): 1 molecular function term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005515protein binding IPI19463981
     
Find genes that share ontologies with NDUFAF3           About GenesLikeMe


Phenotypes:
     2 GenomeRNAi human phenotypes for NDUFAF3:
 Increased gamma-H2AX phosphory  Low eccentricity cells 

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NDUFAF3
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miRNA
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miRTarBase miRNAs that target NDUFAF3:
hsa-let-7a-5p (MIRT052369), hsa-mir-98-5p (MIRT048713), hsa-mir-25-3p (MIRT050200)

Block miRNA regulation of human, mouse, rat NDUFAF3 using miScript Target Protectors
3 qRT-PCR Assays for microRNAs that regulate NDUFAF3:
hsa-miR-362-3p hsa-miR-944 hsa-miR-329
SwitchGear 3'UTR luciferase reporter plasmidNDUFAF3 3' UTR sequence
Inhib. RNA
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(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
NDUF3_HUMAN, Q9BU61: Nucleus (By similarity). Mitochondrion inner membrane
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
mitochondrion5
nucleus4
cytosol2

Gene Ontology (GO): 3 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus IDA--
GO:0005739mitochondrion ----
GO:0005743mitochondrial inner membrane IDA19463981

Find genes that share ontologies with NDUFAF3           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NDUFAF3
Interactions:

    Search GeneGlobe Interaction Network for NDUFAF3

STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

Selected Interacting proteins for NDUFAF3 (Q9BU612, 3 ENSP000003230764) via UniProtKB, MINT, STRING, and/or I2D (see all 254)
InteractantInteraction Details
GeneCardExternal ID(s)
NDUFS2O753062, 3, ENSP000003569724MINT-8079030 I2D: score=1 STRING: ENSP00000356972
NDUFS3O754892, 3, ENSP000002637744MINT-8079030 I2D: score=1 STRING: ENSP00000263774
ICT1Q141972, 3, ENSP000003015854MINT-8079030 I2D: score=1 STRING: ENSP00000301585
LSM1O151163, ENSP000003105964I2D: score=3 STRING: ENSP00000310596
GEMP550403, ENSP000002975964I2D: score=2 STRING: ENSP00000297596
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Gene Ontology (GO): 1 biological process term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0032981mitochondrial respiratory chain complex I assembly IMP19463981

Find genes that share ontologies with NDUFAF3           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for NDUFAF3 (NDUF3)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for NDUFAF3 gene (5 alternative transcripts): 
NM_199069.1  NM_199070.1  NM_199073.1  NM_199074.1  NM_199417.1  

Unigene Cluster for NDUFAF3:

NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
Hs.31387  [show with all ESTs]
Unigene Representative Sequence: BC111004
6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000326912 ENST00000326925(uc003cvn.3 uc003cvp.3 uc003cvq.3 uc003cvr.3)
ENST00000395458 ENST00000451378 ENST00000496152 ENST00000480392
miRNA
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3 qRT-PCR Assays for microRNAs that regulate NDUFAF3:
hsa-miR-362-3p hsa-miR-944 hsa-miR-329
SwitchGear 3'UTR luciferase reporter plasmidNDUFAF3 3' UTR sequence
Inhib. RNA
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Primer
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OriGene qPCR primer pairs and template standards for NDUFAF3
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  QuantiTect SYBR Green Assays in human, mouse, rat NDUFAF3
  QuantiFast Probe-based Assays in human, mouse, rat NDUFAF3

Additional mRNA sequence: 

AL049955.1 BC002873.2 BC111004.1 

21 DOTS entries:

DT.100696815  DT.95368369  DT.100052885  DT.40235956  DT.92437665  DT.120852572  DT.100818255  DT.92437662 
DT.100044240  DT.95152922  DT.100818254  DT.92437664  DT.95162303  DT.120852592  DT.95259889  DT.100818253 
DT.120852548  DT.100810143  DT.120852558  DT.120852599  DT.120852487 

Selected AceView cDNA sequences (see all 380):

BU932109 BQ923093 BG025610 AI859185 BC002873 AA743372 NM_199417 CA450306 
AW327641 BQ645068 AW006728 BU731006 BU069953 BM507361 CD358942 BM976825 
AA443755 BU579840 BI333181 AI817443 BI829966 AA552562 BF436333 AA534495 

GeneLoc Exon Structure

Selected Alternative Splicing Database (ASD) splice patterns (SP) for NDUFAF3 (see all 6)    About this scheme

ExUns: 1 ^ 2 ^ 3a · 3b · 3c · 3d ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7a · 7b · 7c
SP1:        -     -     -     -     -                                                   
SP2:              -     -     -     -                                                   
SP3:                                                                                    
SP4:                                                                                    
SP5:                                            -                                       


ECgene alternative splicing isoforms for NDUFAF3

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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NDUFAF3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: AAGGCCGAGT
NDUFAF3 Expression
About this image

NDUFAF3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

NDUFAF3 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.31387
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(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for NDUFAF3 gene from Selected species (see all 13)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Ndufaf31 , 5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, more1, 5 79.17(n)1
80.43(a)1
  9 (59.50 cM)5
667061  NM_023247.11  NP_075736.11 
 1085658665 
lizard
(Anolis carolinensis)
Reptilia NDUFAF36
NADH dehydrogenase (ubiquinone) complex I, assembl...
53(a)
1 ↔ 1
2(187882355-187887562)
tropical clawed frog
(Xenopus tropicalis)
Amphibia Str.157602 Transcribed sequence with weak similarity to protein more 76.12(n)    137731791 
zebrafish
(Danio rerio)
Actinopterygii ndufaf31 NADH dehydrogenase (ubiquinone) complex I, assembly more 64.6(n)
63.45(a)
  791133  NM_001080615.1  NP_001074084.1 
fruit fly
(Drosophila melanogaster)
Insecta CG55691 CG5569 52.49(n)
41.73(a)
  37783  NM_137996.4  NP_611840.1 
worm
(Caenorhabditis elegans)
Secernentea nuaf-31 nuaf-3 46.43(n)
40.71(a)
  187686  NM_001028158.2  NP_001023329.1 


ENSEMBL Gene Tree for NDUFAF3 (if available)
TreeFam Gene Tree for NDUFAF3 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for NDUFAF3 gene
2 SIMAP similar genes for NDUFAF3 using alignment to 1 protein entry:     NDUF3_HUMAN:
C3orf60    DKFZp564J0123

Find genes that share paralogs with NDUFAF3           About GenesLikeMe


1 Pseudogenes.org Pseudogene for NDUFAF3
PGOHUM00000259850


(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for NDUFAF3 (see all 17)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 3 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
VAR_0584914
Mitochondrial complex I deficiency (MT-C1D)4--see VAR_0584912 G R mis40--------
VAR_0584924
Mitochondrial complex I deficiency (MT-C1D)4--see VAR_0584922 R P mis40--------
rs2011439451,2
--49060543(+) CTGGAA/GCTGCT 8 T A mis10--------
rs1170517911,2
C,F--49060703(+) ATAATA/GATTTA 4 -- ut311Minor allele frequency- G:0.02EA 120
rs781168291,2
--49060799(+) AAGGAC/GTCACT 4 -- ut310--------
rs1509136531,2
C--49060805(+) CACTT-/GTTTCA 4 -- ut310--------
rs130851631,2
C,F--49061075(+) tagagG/Acccct 4 -- ds50012Minor allele frequency- A:0.50NA 4
rs1499139731,2
C--49061180(+) TGCAAA/CCTCCG 4 -- ds50010--------
rs3723441651,2
----49061123(+) ATGAG-/GAGTCTTG 8 -- ds5001 cds10--------
rs717167211,2
----49060718(+) CTTCT-/CCCATT 4 -- ut310--------

HapMap Linkage Disequilibrium report for NDUFAF3 (49057892 - 49060928 bp)

Structural Variations
     Database of Genomic Variants (DGV) 1 variation for NDUFAF3:    About this table    
Variant IDTypeSubtypePubMed ID
nsv876764CNV Loss21882294

Human Gene Mutation Database (HGMD): NDUFAF3
Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing NDUFAF3
DNA2.0 Custom Variant and Variant Library Synthesis for NDUFAF3

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 612911   
OMIM disorders: 252010  
UniProtKB/Swiss-Prot: NDUF3_HUMAN, Q9BU61
  • Mitochondrial complex I deficiency (MT-C1D) [MIM:252010]: A disorder of the mitochondrial respiratory
    chain that causes a wide range of clinical manifestations from lethal neonatal disease to adult-onset
    neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specific
    encephalopathy, cardiomyopathy, myopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and
    some forms of Parkinson disease. Note=The disease is caused by mutations affecting the gene represented in this
    entry

  • 1 disease for NDUFAF3:    
    About MalaCards
    mitochondrial complex i deficiency


    Find genes that share disorders with NDUFAF3           About GenesLikeMe

    Genetic Association Database (GAD): NDUFAF3
    Human Genome Epidemiology (HuGE) Navigator: NDUFAF3 (1 document)

    Export disorders for NDUFAF3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NDUFAF3 gene, integrated from 10 sources (see all 17):
    (articles sorted by number of sources associating them with NDUFAF3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. 2P1, a novel male mouse cDNA specifically expressed during meiosis. (PubMed id 12653254)1, 3, 9 Hammami-Hamza S....Finaz C. (Int. J. Dev. Biol. 2003)
    2. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    3. Mutations in NDUFAF3 (C3ORF60), encoding an NDUFAF4 (C6ORF66)- interacting complex I assembly protein, cause fatal neonatal mitochondrial disease. (PubMed id 19463981)1, 2 Saada A....Nijtmans L.G. (Am. J. Hum. Genet. 2009)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Molecular cloning of a novel alternatively spliced nuclear protein. (PubMed id 9349717)1, 3 Hartmann A.M. and Stamm S. (Biochim. Biophys. Acta 1997)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    8. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    9. Proteomic profiling of Myc-associated proteins. (PubMed id 21150319)1 Agrawal P....Sedivy J.M. (Cell Cycle 2010)
    10. A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome. (PubMed id 20186120)1 Richter R....Chrzanowska-Lightowlers Z.M. (EMBO J. 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 25915 HGNC: 29918 AceView: DKFZP564J0123 Ensembl:ENSG00000178057 euGenes: HUgn25915
    ECgene: NDUFAF3 H-InvDB: NDUFAF3

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for NDUFAF3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NDUFAF3 gene:
    Search GeneIP for patents involving NDUFAF3

    GeneCards and IP:
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