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NDUFA7 Gene

protein-coding   GIFtS: 61
GCID: GC19M008376

NADH Dehydrogenase (Ubiquinone) 1 Alpha Subcomplex, 7, 14.5kDa

(Previous names: NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7 (14.5kD,...)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
NADH Dehydrogenase (Ubiquinone) 1 Alpha Subcomplex, 7, 14.5kDa1 2     NADH Dehydrogenase (Ubiquinone) 1 Alpha Subcomplex, 7 (14.5kD, B14.5a)1
Complex I B14.5a Subunit1 2     B14.5a2
CI-B14.5a2 3     NADH Dehydrogenase [Ubiquinone] 1 Alpha Subcomplex Subunit 72
NADH-Ubiquinone Oxidoreductase Subunit B14.5a2 3     Complex I-B14.5a3

External Ids:    HGNC: 76911   Entrez Gene: 47012   Ensembl: ENSG000002678557   OMIM: 6021395   UniProtKB: O951823   
ORGUL members:         

Export aliases for NDUFA7 gene to outside databases

Previous GC identifers: GC19P008156 GC19M008466 GC19M008268 GC19M008283 GC19M008284 GC19M008285 GC19M008286 GC19M008030


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for NDUFA7 Gene:
This gene encodes a subunit of NADH:ubiquinone oxidoreductase (complex I), which is a multiprotein complex located
in the inner mitochondrial membrane. Complex I functions in the transfer of electrons from NADH to the
respiratory chain. (provided by RefSeq, Mar 2011)

GeneCards Summary for NDUFA7 Gene:
NDUFA7 (NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa) is a protein-coding gene. GO annotations related to this gene include NADH dehydrogenase (ubiquinone) activity.

UniProtKB/Swiss-Prot: NDUA7_HUMAN, O95182
Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that
is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the
respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000019.10  NT_011295.12  NC_018930.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the NDUFA7 gene promoter:
         Bach2   AP-2gamma   GATA-2   C/EBPalpha   CHOP-10   CREB   CP2   deltaCREB   c-Myb   AP-2alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNDUFA7 promoter sequence
   Search Chromatin IP Primers for NDUFA7

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NDUFA7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.2   Ensembl cytogenetic band:  19p13.2   HGNC cytogenetic band: 19p13.2

NDUFA7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NDUFA7 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M008376:  view genomic region     (about GC identifiers)

Start:
8,373,490 bp from pter      End:
8,386,280 bp from pter
Size:
12,791 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: NDUA7_HUMAN, O95182 (See protein sequence)
Recommended Name: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7  
Size: 113 amino acids; 12551 Da
Subunit: Complex I is composed of 45 different subunits
Sequence caution: Sequence=AAC99399.1; Type=Erroneous initiation;

Explore the universe of human proteins at neXtProt for NDUFA7: NX_O95182

Explore proteomics data for NDUFA7 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys23
  • Modification sites at PhosphoSitePlus

  • See NDUFA7 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_004992.2  
    ENSEMBL proteins: 
     ENSP00000471333   ENSP00000470962   ENSP00000471943   ENSP00000301457  
    Reactome Protein details: O95182

    NDUFA7 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    comI: Mitochondrial respiratory chain complex / Complex I

    1 InterPro protein domain:
     IPR009947 NADH-UbQ_OxRdtase_B14.5a_su

    Graphical View of Domain Structure for InterPro Entry O95182

    ProtoNet protein and cluster: O95182

    1 Blocks protein domain: IPB009947 NADH:ubiquinone oxidoreductase subunit B14.5a

    UniProtKB/Swiss-Prot: NDUA7_HUMAN, O95182
    Similarity: Belongs to the complex I NDUFA7 subunit family


    Find genes that share domains with NDUFA7           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NDUA7_HUMAN, O95182
    Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that
    is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the
    respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

         Genatlas biochemistry entry for NDUFA7:
    NADH ubiquinone oxidoreductase (Q reductase),14.5kDa,component alpha 7,hydrophobic fraction of the complex I
    multi-subunit enzyme of the oxidative phosphorylation (OXPHOS),inner mitochondrial membrane

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008137NADH dehydrogenase (ubiquinone) activity NAS9878551
         
    Find genes that share ontologies with NDUFA7           About GenesLikeMe


    Phenotypes:
         3 GenomeRNAi human phenotypes for NDUFA7:
     Elongated cells  Increased G1 DNA content  Increased number of mitotic ce 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NDUFA7
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    miRNA
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    miRTarBase miRNAs that target NDUFA7:
    hsa-mir-186-5p (MIRT044972), hsa-mir-92a-3p (MIRT049502)

    Block miRNA regulation of human, mouse, rat NDUFA7 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate NDUFA7:
    hsa-miR-3173-3p
    SwitchGear 3'UTR luciferase reporter plasmidNDUFA7 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NDUA7_HUMAN, O95182: Mitochondrion inner membrane; Peripheral membrane protein; Matrix side
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5
    cytosol1
    extracellular1
    nucleus1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005743mitochondrial inner membrane TAS--
    GO:0005747mitochondrial respiratory chain complex I NAS9878551

    Find genes that share ontologies with NDUFA7           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for NDUFA7 About    
    See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
    Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.0.81
    Parkinson's disease0.57
    Respiratory electron transport0.81
    Oxidative phosphorylation0.51
    Electron Transport Chain0.75
    Huntington's disease0.45
    The citric acid (TCA) cycle and respiratory electron transport0.71
    Non-alcoholic fatty liver disease (NAFLD)0.41
    2Metabolism
    Metabolism0.38
    Metabolic pathways0.38
    3Alzheimer's disease
    Alzheimer's disease0.44


    Find genes that share SuperPaths with NDUFA7           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 BioSystems Pathways for NDUFA7
        Oxidative phosphorylation
    Electron Transport Chain


    1 Reactome Pathway for NDUFA7
        Respiratory electron transport


    Selected Kegg Pathways  (Kegg details for NDUFA7) (see all 6):
        Oxidative phosphorylation
    Metabolic pathways
    Non-alcoholic fatty liver disease (NAFLD)
    Alzheimer's disease
    Parkinson's disease

        Pathway & Disease-focused RT2 Profiler PCR Array including NDUFA7: 
              Mitochondrial Energy Metabolism in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for NDUFA7

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for NDUFA7 (O951822, 3 ENSP000003014574) via UniProtKB, MINT, STRING, and/or I2D (see all 60)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    STARD9Q9P2P62, 3, ENSP000002906074MINT-63273 I2D: score=4 STRING: ENSP00000290607
    ELAC2Q9BQ522, 3MINT-63272 I2D: score=4 
    PRKAB1Q9Y4782, 3, ENSP000002293284MINT-63274 I2D: score=5 STRING: ENSP00000229328
    NDUFA2O436783, ENSP000002521024I2D: score=1 STRING: ENSP00000252102
    MDFIQ997503, ENSP000002303214I2D: score=1 STRING: ENSP00000230321
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006120mitochondrial electron transport, NADH to ubiquinone NAS9878551
    GO:0022904respiratory electron transport chain TAS--
    GO:0042773ATP synthesis coupled electron transport ----
    GO:0044237cellular metabolic process TAS--
    GO:0044281small molecule metabolic process TAS--

    Find genes that share ontologies with NDUFA7           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NDUFA7 (NDUA7)

    8 HMDB Compounds for NDUFA7    About this table
    CompoundSynonyms CAS #PubMed Ids
    FAD1H-Purin-6-amine flavin dinucleotide (see all 21)146-14-5--
    IronArmco iron (see all 19)7439-89-6--
    NAD3-Carbamoyl-1-D-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate (see all 28)53-84-9--
    NADH1,4-Dihydronicotinamide adenine dinucleotide (see all 17)58-68-4--
    QH2CoQH2 (see all 5)56275-39-9--
    SulfideSulfide (see all 4)18496-25-8--
    Ubiquinone Q1Coenzyme Q (see all 9)727-81-1--
    Ubiquinone Q22-(3,7-dimethyl-2,6-octadienyl)-5,6-dimethoxy-3-methyl-2,5-Cyclohexadiene-1,4-dione (see all 7)606-06-4--

    1 DrugBank Compound for NDUFA7    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    NADHbeta-DPNH (see all 18)606-68-8target--17139284 17016423



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for NDUFA7 gene: 
    NM_005001.3  

    Unigene Cluster for NDUFA7:

    NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa
    Hs.333427  [show with all ESTs]
    Unigene Representative Sequence: AK056039
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000601101 ENST00000593729 ENST00000595856 ENST00000602059 ENST00000301457(uc002mjm.2)
    ENST00000601258
    miRNA
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    1 qRT-PCR Assays for microRNA that regulate NDUFA7:
    hsa-miR-3173-3p
    SwitchGear 3'UTR luciferase reporter plasmidNDUFA7 3' UTR sequence
    Inhib. RNA
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      QuantiFast Probe-based Assays in human, mouse, rat NDUFA7

    Additional mRNA sequence: 

    AF050637.1 AF054178.1 AK056039.1 BC003102.1 BC107892.1 CR456915.1 CR542266.1 

    17 DOTS entries:

    DT.99946473  DT.316588  DT.121498037  DT.100822533  DT.92384798  DT.100050789  DT.91748043  DT.100670984 
    DT.40109229  DT.100822534  DT.100843907  DT.91795863  DT.101972516  DT.100822532  DT.95199964  DT.121497978 
    DT.423237 

    Selected AceView cDNA sequences (see all 537):

    AA873215 BG058740 BM708309 BI489876 BM795432 BI754997 AA749262 CD671581 
    BU543226 BC066124 AF161254 CB106682 CR603782 BE313915 BE382788 AW024981 
    BG164140 BQ012874 CB141050 BM750449 CA489619 AF050637 BU194469 CF528604 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NDUFA7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCGTCGCAGA
    NDUFA7 Expression
    About this image


    NDUFA7 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Gut Tube (Gastrointestinal Tract)
             Foregut
     
     Neurons
             nGnG Amacrine Cells Inner Nuclear Layer
     
     Eye (Sensory Organs)
             nGnG Amacrine Cells Inner Nuclear Layer
    NDUFA7 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NDUFA7 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.333427
        Pathway & Disease-focused RT2 Profiler PCR Array including NDUFA7: 
              Mitochondrial Energy Metabolism in human mouse rat

    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NDUFA7

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for NDUFA7 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ndufa71 , 5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, more1, 5 84.96(n)1
    91.15(a)1
      17 (17.98 cM)5
    664161  NM_023202.41  NP_075691.11 
     338245915 
    chicken
    (Gallus gallus)
    Aves NDUFA71 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, more 68.14(n)
    67.26(a)
      420065  XM_004948672.1  XP_004948729.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    59(a)
    1 → many
    1(149131783-149132133)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.65362 Xenopus laevis transcribed sequence with moderate similarity more 71.26(n)    AW635275.1 
    zebrafish
    (Danio rerio)
    Actinopterygii ndufa71 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, more 58.33(n)
    65.38(a)
      445042  NM_001003436.2  NP_001003436.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG36216
    CG69146
    --
    40(a)
    22(a)
    many ↔ many
    many ↔ many
    X(2066561-2067170)
    3L(22599469-22600226)


    ENSEMBL Gene Tree for NDUFA7 (if available)
    TreeFam Gene Tree for NDUFA7 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for NDUFA7 gene
    9 SIMAP similar genes for NDUFA7 using alignment to 6 protein entries:     NDUA7_HUMAN (see all proteins):
    FAM175A    COPS7B    MEF2BNB    RANBP3    C19orf82    FP1523
    HDGFRP2    TBC1D22A    TMEM145

    Find genes that share paralogs with NDUFA7           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NDUFA7 (see all 317)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1920426431,2
    --8311954(+) CGGGCA/GGATCA 1 -- ds50010--------
    rs1829947371,2
    --8312055(+) CTACTC/TGGGAG 1 -- ds50010--------
    rs37606831,2
    C--8312056(+) TACTCA/GGGAGG 1 -- ds50010--------
    rs1126642271,2
    C--8312127(+) TGCGTT/ACCAGC 1 -- ds50011Minor allele frequency- A:0.50WA 2
    rs734954981,2
    C--8312141(+) GGTGAC/AAAGCG 1 -- ds50011Minor allele frequency- A:0.50WA 2
    rs1400596661,2
    --8312251(+) AATGGC/TTTCTG 1 -- ds50010--------
    rs1886737811,2
    --8312332(+) TTCCCC/TGTTGA 1 -- ds50010--------
    rs1500670971,2
    --8312414(+) GGTGTG/TGTGGC 1 -- ds50010--------
    rs1932717991,2
    --8312448(+) TGGGAA/GGTCAA 1 -- ut310--------
    rs356698301,2
    C,F--8312466(+) GGATCG/ACTTGA 1 -- ut313Minor allele frequency- A:0.33NA 6

    HapMap Linkage Disequilibrium report for NDUFA7 (8373490 - 8386280 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for NDUFA7:    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv620e199CNV Deletion23128226
    dgv3718n71CNV Loss21882294
    nsv2401CNV Loss18451855

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NDUFA7
    DNA2.0 Custom Variant and Variant Library Synthesis for NDUFA7

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 602139    OMIM disorders: --


    Find genes that share disorders with NDUFA7           About GenesLikeMe

    Genetic Association Database (GAD): NDUFA7
    Human Genome Epidemiology (HuGE) Navigator: NDUFA7 (4 documents)

    Export disorders for NDUFA7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NDUFA7 gene, integrated from 10 sources (see all 23):
    (articles sorted by number of sources associating them with NDUFA7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    2. Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. (PubMed id 19343046)1, 4 Saito A....Kamatani N. (J. Hum. Genet. 2009)
    3. Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey. (PubMed id 18977241)1, 4 Starr J.M....Deary I.J. (Mech. Ageing Dev. 2008)
    4. A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition. (PubMed id 17601350)1, 4 Harris S.E....Deary I.J. (BMC Genet. 2007)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification. (PubMed id 12611891)1, 2 Murray J.... Capaldi R.A. (J. Biol. Chem. 2003)
    7. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (Genome Res. 2000)
    8. cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed. (PubMed id 9878551)1, 2 Loeffen J.L.C.M.... Smeitink J.A.M. (Biochem. Biophys. Res. Commun. 1998)
    9. Mapping of the NDUFA2, NDUFA6, NDUFA7, NDUFB8, and NDUFS8 electron transport chain genes by intron based radiation hybrid mapping. (PubMed id 9763676)1, 3 Emahazion T. and Brookes A.J. (Cytogenet. Cell Genet. 1998)
    10. In situ hybridisation mapping of genomic clones for five human respiratory chain complex I genes. (PubMed id 9345899)1, 9 Dunbar D.R....Brookes A.J. (Cytogenet. Cell Genet. 1997)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 4701 HGNC: 7691 AceView: NDUFA7and8D6AandFLJ46061 Ensembl:ENSG00000267855 euGenes: HUgn4701
    ECgene: NDUFA7 Kegg: 4701 H-InvDB: NDUFA7

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for NDUFA7 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for NDUFA7 gene:
    Search GeneIP for patents involving NDUFA7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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