Aliases for NDUFA5 Gene
- NADH:Ubiquinone Oxidoreductase Subunit A5 2 3 5
- NADH-Ubiquinone Oxidoreductase 13 KDa-B Subunit 2 3 4
- NADH Dehydrogenase (Ubiquinone) 1 Alpha Subcomplex, 5, 13kDa 2 3
- NADH Dehydrogenase (Ubiquinone) 1 Alpha Subcomplex, 5 2 3
- Complex I 13kDa Subunit B 2 3
- Complex I Subunit B13 3 4
- Type I Dehydrogenase 2 3
- Ubiquinone Reductase 2 3
External Ids for NDUFA5 Gene
Previous GeneCards Identifiers for NDUFA5 Gene
This nuclear gene encodes a conserved protein that comprises the B13 subunit of complex I of the mitochondrial respiratory chain. The encoded protein localizes to the inner mitochondrial membrane, where it is thought to aid in the transfer of electrons from NADH to ubiquinone. Alternative splicing results in multiple transcript variants. There are numerous pseudogenes of this gene on chromosomes 1, 3, 6, 8, 9, 11, 12, and 16. [provided by RefSeq, Apr 2014]
GeneCards Summary for NDUFA5 Gene
NDUFA5 (NADH:Ubiquinone Oxidoreductase Subunit A5) is a Protein Coding gene. Diseases associated with NDUFA5 include leber hereditary optic neuropathy and korean hemorrhagic fever. Among its related pathways are Metabolism and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. GO annotations related to this gene include NADH dehydrogenase (ubiquinone) activity and oxidoreductase activity, acting on NAD(P)H.
UniProtKB/Swiss-Prot for NDUFA5 Gene
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.