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NDUFA3 Gene

protein-coding   GIFtS: 54
GCID: GC19P054590

NADH Dehydrogenase (Ubiquinone) 1 Alpha Subcomplex, 3, 9kDa

(Previous names: NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3 (9kD,...)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
NADH Dehydrogenase (Ubiquinone) 1 Alpha Subcomplex, 3, 9kDa1 2     NADH-Ubiquinone Oxidoreductase B9 Subunit2 3
Complex I B9 Subunit1 2     NADH Dehydrogenase (Ubiquinone) 1 Alpha Subcomplex, 3 (9kD, B9)1
Complex I-B92 3     B92
CI-B92 3     NADH Dehydrogenase [Ubiquinone] 1 Alpha Subcomplex Subunit 32

External Ids:    HGNC: 76861   Entrez Gene: 46962   Ensembl: ENSG000001709067   OMIM: 6038325   UniProtKB: O951673   

Export aliases for NDUFA3 gene to outside databases

Previous GC identifers: GC19P055251 GC19P055030 GC19P059282 GC19P059297 GC19P050923


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for NDUFA3 Gene:
NDUFA3 (NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa) is a protein-coding gene. GO annotations related to this gene include NADH dehydrogenase (ubiquinone) activity.

UniProtKB/Swiss-Prot: NDUA3_HUMAN, O95167
Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that
is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the
respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000019.9  NC_018930.2  NT_011109.17  NT_187693.1  
Regulatory elements:
   Regulatory transcription factor binding sites in the NDUFA3 gene promoter:
         c-Fos   NF-1   NF-1/L   AP-1   AML1a   Pax-2   Pax-2a   YY1   COMP1   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): NDUFA3 promoter sequence
   Search Chromatin IP Primers for NDUFA3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NDUFA3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.42   Ensembl cytogenetic band:  19q13.42   HGNC cytogenetic band: 19q13.42

NDUFA3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NDUFA3 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P054590:  view genomic region     (about GC identifiers)

Start:
54,606,036 bp from pter      End:
54,612,564 bp from pter
Size:
6,529 bases      Orientation:
plus strand

Selected alternative locations (see all 8):
Chr19+,NW_003571057 77,273-81,394      Chr19+,NW_003571056 77,273-81,394      Chr19+,NW_003571058 77,273-81,394     
Chr19+,NW_003571055 77,273-81,394      Chr19+,NW_003571060 77,273-81,394      Chr19+,NW_003571061 77,273-81,394     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: NDUA3_HUMAN, O95167 (See protein sequence)
Recommended Name: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3  
Size: 84 amino acids; 9279 Da
Subunit: Complex I is composed of 45 different subunits

Explore the universe of human proteins at neXtProt for NDUFA3: NX_O95167

Explore proteomics data for NDUFA3 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys47
  • Modification sites at PhosphoSitePlus

  • See NDUFA3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_004533.1  
    ENSEMBL proteins: 
     ENSP00000412325   ENSP00000398290   ENSP00000418438   ENSP00000375642   ENSP00000474705  
     ENSP00000410453   ENSP00000375643   ENSP00000375644   ENSP00000474408   ENSP00000407335  
     ENSP00000394383  
    Reactome Protein details: O95167

    NDUFA3 Human Recombinant Protein Products:

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    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
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    antibodies-online proteins for NDUFA3 (2 products) 

     
    antibodies-online peptides for NDUFA3

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    antibodies-online antibodies for NDUFA3 (20 products) 

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    antibodies-online kits for NDUFA3 (6 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    comI: Mitochondrial respiratory chain complex / Complex I

    1 InterPro protein domain:
     IPR026626 NDUFA3

    Graphical View of Domain Structure for InterPro Entry O95167

    ProtoNet protein and cluster: O95167

    UniProtKB/Swiss-Prot: NDUA3_HUMAN, O95167
    Similarity: Belongs to the complex I NDUFA3 subunit family


    Find genes that share domains with NDUFA3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NDUA3_HUMAN, O95167
    Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that
    is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the
    respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008137NADH dehydrogenase (ubiquinone) activity NAS9878551
         
    Find genes that share ontologies with NDUFA3           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for NDUFA3:
     Increased G2M DNA content  Increased number of mitotic ce 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for NDUFA3

    miRNA
    Products:
        
    miRTarBase miRNAs that target NDUFA3:
    hsa-let-7e-5p (MIRT051531), hsa-mir-320a (MIRT044766), hsa-mir-671-5p (MIRT039275)

    Block miRNA regulation of human, mouse, rat NDUFA3 using miScript Target Protectors
    4 qRT-PCR Assays for microRNAs that regulate NDUFA3:
    hsa-miR-23b hsa-miR-130a* hsa-miR-23a hsa-miR-23c
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NDUA3_HUMAN, O95167: Mitochondrion inner membrane; Single-pass membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5
    extracellular3
    endoplasmic reticulum1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IDA--
    GO:0005743mitochondrial inner membrane TAS--
    GO:0005747mitochondrial respiratory chain complex I NAS9878551
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with NDUFA3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for NDUFA3 About    
    See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
    Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.0.81
    Parkinson's disease0.57
    Respiratory electron transport0.81
    Oxidative phosphorylation0.51
    Electron Transport Chain0.75
    Huntington's disease0.45
    The citric acid (TCA) cycle and respiratory electron transport0.71
    Non-alcoholic fatty liver disease (NAFLD)0.41
    2Metabolism
    Metabolism0.38
    Metabolic pathways0.38
    3Alzheimer's disease
    Alzheimer's disease0.44


    Find genes that share SuperPaths with NDUFA3           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 BioSystems Pathways for NDUFA3
        Oxidative phosphorylation
    Electron Transport Chain


    1 Reactome Pathway for NDUFA3
        Respiratory electron transport


    Selected Kegg Pathways  (Kegg details for NDUFA3) (see all 6):
        Oxidative phosphorylation
    Metabolic pathways
    Non-alcoholic fatty liver disease (NAFLD)
    Alzheimer's disease
    Parkinson's disease

        Pathway & Disease-focused RT2 Profiler PCR Array including NDUFA3: 
              Mitochondrial Energy Metabolism in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for NDUFA3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for NDUFA3 (ENSP000003982904) via UniProtKB, MINT, STRING, and/or I2D (see all 55)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NDUFC1ENSP000003777704STRING: ENSP00000377770 STRING: ENSP00000265500
    CYC1ENSP000003171594STRING: ENSP00000317159
    MT-CYBENSP000003545544STRING: ENSP00000354554
    MT-ND1ENSP000003546874STRING: ENSP00000354687
    MT-ND4LENSP000003547284STRING: ENSP00000354728
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006120mitochondrial electron transport, NADH to ubiquinone NAS9878551
    GO:0022904respiratory electron transport chain TAS--
    GO:0044237cellular metabolic process TAS--
    GO:0044281small molecule metabolic process TAS--

    Find genes that share ontologies with NDUFA3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NDUFA3 (NDUA3)

    8 HMDB Compounds for NDUFA3    About this table
    CompoundSynonyms CAS #PubMed Ids
    FAD1H-Purin-6-amine flavin dinucleotide (see all 21)146-14-5--
    IronArmco iron (see all 19)7439-89-6--
    NAD3-Carbamoyl-1-D-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate (see all 28)53-84-9--
    NADH1,4-Dihydronicotinamide adenine dinucleotide (see all 17)58-68-4--
    QH2CoQH2 (see all 5)56275-39-9--
    SulfideSulfide (see all 4)18496-25-8--
    Ubiquinone Q1Coenzyme Q (see all 9)727-81-1--
    Ubiquinone Q22-(3,7-dimethyl-2,6-octadienyl)-5,6-dimethoxy-3-methyl-2,5-Cyclohexadiene-1,4-dione (see all 7)606-06-4--

    1 DrugBank Compound for NDUFA3    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    NADHbeta-DPNH (see all 18)606-68-8target--17139284 17016423



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for NDUFA3 gene: 
    NM_004542.3  

    Unigene Cluster for NDUFA3:

    NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa
    Hs.198269  [show with all ESTs]
    Unigene Representative Sequence: CD248715
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000417903(uc002qdf.3) ENST00000419113(uc002qde.3) ENST00000485876
    ENST00000391762 ENST00000471292 ENST00000451517 ENST00000391763 ENST00000391764
    ENST00000484103 ENST00000303553 ENST00000422029 ENST00000420296 ENST00000480713
    ENST00000482960
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    Inhib. RNA
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      QuantiFast Probe-based Assays in human, mouse, rat NDUFA3

    Additional mRNA sequence: 

    AF044955.1 AF070653.1 AK289489.1 BC011021.1 BC022369.1 BC061644.1 CR542143.1 

    14 DOTS entries:

    DT.447997  DT.97804952  DT.100735816  DT.121451717  DT.100785884  DT.95270160  DT.121451743  DT.86835744 
    DT.91967036  DT.121451833  DT.91837942  DT.95287028  DT.92428332  DT.95270166 

    Selected AceView cDNA sequences (see all 160):

    AI362796 AI342995 AI885387 AA813127 CA312034 AA970515 BE855858 BM548739 
    AI814011 AA255557 BE621354 AI675759 BI755491 BU741250 BU838806 BF939295 
    AI148243 F25043 BC061644 AA255573 F21180 C01859 BE741214 AA339117 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for NDUFA3    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4
    SP1:                                    
    SP2:                          -         


    ECgene alternative splicing isoforms for NDUFA3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NDUFA3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCCGACGTGC
    NDUFA3 Expression
    About this image


    NDUFA3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 15) fully expand
     
     Brain (Nervous System)
             Cerebral Cortex
     
     Colon (Gastrointestinal Tract)
     
     Kidney (Urinary System)
     
     Thyroid (Endocrine System)
     
     Lung (Respiratory System)
    NDUFA3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NDUFA3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.198269
        Pathway & Disease-focused RT2 Profiler PCR Array including NDUFA3: 
              Mitochondrial Energy Metabolism in human mouse rat

    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NDUFA3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for NDUFA3 gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ndufa31 , 5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, more1, 5 82.14(n)1
    80.95(a)1
      7 (2.08 cM)5
    660911  NM_025348.21  NP_079624.11 
     36173735 
    lizard
    (Anolis carolinensis)
    Reptilia NDUFA36
    NADH dehydrogenase (ubiquinone) 1 alpha subcomplex...
    67(a)
    1 ↔ 1
    GL343279.1(1534812-1536114)
    African clawed frog
    (Xenopus laevis)
    Amphibia BX855037.12   -- 77.15(n)    BX855037.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BI703424.12   -- 71.13(n)    BI703424.1 


    ENSEMBL Gene Tree for NDUFA3 (if available)
    TreeFam Gene Tree for NDUFA3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for NDUFA3 gene

    Find genes that share paralogs with NDUFA3           About GenesLikeMe


    Selected Pseudogenes.org Pseudogenes for NDUFA3 (see all 6)
    PGOHUM00000242346 PGOHUM00000248663 PGOHUM00000247270 PGOHUM00000249056 PGOHUM00000234718


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NDUFA3 (see all 114)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0361754
    A breast cancer sample4--see VAR_0361752 N D mis40--------
    rs1890868751,2
    C--50920026(+) GGGGTA/GACTCA 1 -- us2k10--------
    rs1512012451,2
    --50920084(+) ATACCC/TGCTAG 1 -- us2k10--------
    rs2542591,2
    C,F,A,H--54606405(-) GCAAGG/AAGCGT 1 -- int128Minor allele frequency- A:0.49EA NS NA WA CSA EU 4586
    rs1139662691,2
    C--54606420(+) CCTTCA/G/TGGAGT 1 -- spa11CSA 1
    rs1129980241,2
    C--54606421(+) CTTCAA/C/GGAGTC 1 -- spa11CSA 1
    rs1506178091,2
    F--54606436(+) CCTTCC/ATCAAG 2 /I /L mis11Minor allele frequency- A:0.00NA 4538
    rs1387584391,2
    C,F--54606446(+) GAATGC/GCTGGG 2 A G mis11Minor allele frequency- G:0.00NA 4536
    rs1123647151,2
    C--54606497(+) CCTCGC/GTGCGT 1 -- spd11Minor allele frequency- G:0.00CSA 1
    rs1120590661,2
    C--54606534(+) GTCCAC/TCCCCG 1 -- int11Minor allele frequency- T:0.50WA 2

    HapMap Linkage Disequilibrium report for NDUFA3 (54606036 - 54612564 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for NDUFA3:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2718812CNV Deletion23290073
    nsv510773CNV Loss20534489
    nsv515623CNV Loss19592680
    nsv833877CNV Loss17160897
    dgv4001n71CNV Loss21882294
    nsv470157CNV Loss18288195

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 603832    OMIM disorders: --


    Find genes that share disorders with NDUFA3           About GenesLikeMe

    Genetic Association Database (GAD): NDUFA3
    Human Genome Epidemiology (HuGE) Navigator: NDUFA3 (5 documents)

    Export disorders for NDUFA3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NDUFA3 gene, integrated from 10 sources (see all 17):
    (articles sorted by number of sources associating them with NDUFA3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed. (PubMed id 9878551)1, 2, 3 Loeffen J.L.C.M.... Smeitink J.A.M. (Biochem. Biophys. Res. Commun. 1998)
    2. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    3. Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. (PubMed id 19343046)1, 4 Saito A....Kamatani N. (J. Hum. Genet. 2009)
    4. Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey. (PubMed id 18977241)1, 4 Starr J.M....Deary I.J. (Mech. Ageing Dev. 2008)
    5. A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition. (PubMed id 17601350)1, 4 Harris S.E....Deary I.J. (BMC Genet. 2007)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification. (PubMed id 12611891)1, 2 Murray J.... Capaldi R.A. (J. Biol. Chem. 2003)
    8. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (Genome Res. 2000)
    9. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    10. Genetic association with overall survival of taxane-treated lung cancer patients - a genome-wide association study in human lymphoblastoid cell lines followed by a clinical association study. (PubMed id 23006423)1 Niu N....Wang L. (BMC Cancer 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 4696 HGNC: 7686 AceView: NDUFA3 Ensembl:ENSG00000170906 euGenes: HUgn4696
    ECgene: NDUFA3 Kegg: 4696 H-InvDB: NDUFA3

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for NDUFA3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NDUFA3 gene:
    Search GeneIP for patents involving NDUFA3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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