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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NDUFA3 Gene

protein-coding   GIFtS: 52
GCID: GC19P054590

NADH Dehydrogenase (Ubiquinone) 1 Alpha Subcomplex, 3, 9kDa

(Previous names: NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3 (9kD,...)
Alzheimer's & Parkinson's Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
NADH Dehydrogenase (Ubiquinone) 1 Alpha Subcomplex, 3, 9kDa1 2     NADH-Ubiquinone Oxidoreductase B9 Subunit2 3
Complex I B9 Subunit1 2     NADH Dehydrogenase (Ubiquinone) 1 Alpha Subcomplex, 3 (9kD, B9)1
Complex I-B92 3     B92
CI-B92 3     NADH Dehydrogenase [Ubiquinone] 1 Alpha Subcomplex Subunit 32

External Ids:    HGNC: 76861   Entrez Gene: 46962   Ensembl: ENSG000001709067   OMIM: 6038325   UniProtKB: O951673   

Export aliases for NDUFA3 gene to outside databases

Previous GC identifers: GC19P055251 GC19P055030 GC19P059282 GC19P059297 GC19P050923


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for NDUFA3 Gene: 
NDUFA3 (NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa) is a protein-coding gene. Diseases associated with NDUFA3 include huntington's disease, and chronic lymphocytic leukemia, and among its related super-pathways are Electron Transport Chain and Metabolic pathways. GO annotations related to this gene include NADH dehydrogenase (ubiquinone) activity.

UniProtKB/Swiss-Prot: NDUA3_HUMAN, O95167
Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that
is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the
respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.2  NT_011109.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NDUFA3 gene promoter:
         c-Fos   NF-1   NF-1/L   AP-1   AML1a   Pax-2   Pax-2a   YY1   COMP1   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): NDUFA3 promoter sequence
   Search SABiosciences Chromatin IP Primers for NDUFA3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NDUFA3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.42   Ensembl cytogenetic band:  19q13.42   HGNC cytogenetic band: 19q13.42

NDUFA3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NDUFA3 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P054590:  view genomic region     (about GC identifiers)

Start:
54,606,036 bp from pter      End:
54,612,564 bp from pter
Size:
6,529 bases      Orientation:
plus strand

6/8 alternative locations (see all 8):
Chr19+,NW_003571059 77,273-81,394      Chr19+,NW_003571060 77,273-81,394      Chr19+,NW_003571058 77,273-81,394     
Chr19+,NW_003571057 77,273-81,394      Chr19+,NW_003571056 77,273-81,394      Chr19+,NW_003571055 77,273-81,394     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NDUA3_HUMAN, O95167 (See protein sequence)
Recommended Name: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3  
Size: 84 amino acids; 9279 Da
Subunit: Complex I is composed of 45 different subunits
Subcellular location: Mitochondrion inner membrane; Single-pass membrane protein

Explore the universe of human proteins at neXtProt for NDUFA3: NX_O95167

Explore proteomics data for NDUFA3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O95167

  • NDUFA3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NDUFA3 Protein Expression
    REFSEQ proteins: NP_004533.1  
    ENSEMBL proteins: 
     ENSP00000412325   ENSP00000398290   ENSP00000418438   ENSP00000375642   ENSP00000474705  
     ENSP00000410453   ENSP00000375643   ENSP00000375644   ENSP00000474408   ENSP00000407335  
     ENSP00000394383  
    Reactome Protein details: O95167
    Human Recombinant Protein Products for NDUFA3: 
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion ----
    GO:0005743mitochondrial inner membrane TAS--
    GO:0005747mitochondrial respiratory chain complex I NAS9878551
    GO:0016021integral to membrane IEA--

    NDUFA3 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    comI: Mitochondrial respiratory chain complex / Complex I

    1 InterPro protein domain:
     IPR026626 NDUFA3

    Graphical View of Domain Structure for InterPro Entry O95167

    ProtoNet protein and cluster: O95167

    UniProtKB/Swiss-Prot: NDUA3_HUMAN, O95167
    Similarity: Belongs to the complex I NDUFA3 subunit family


    NDUFA3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NDUA3_HUMAN, O95167
    Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that
    is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the
    respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008137NADH dehydrogenase (ubiquinone) activity NAS9878551
         
    NDUFA3 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for NDUFA3:
     Increased G2M DNA content  Increased number of mitotic ce 

    Animal Models:
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    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for NDUFA3 About                                                                                                See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
    Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.0.81
    Parkinson's disease0.61
    Respiratory electron transport0.81
    Oxidative phosphorylation0.51
    Electron Transport Chain0.75
    Huntington's disease0.47
    The citric acid (TCA) cycle and respiratory electron transport0.72
    Alzheimer's disease0.46
    2Metabolism
    Metabolism0.40
    Metabolic pathways0.40

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 BioSystems Pathways for NDUFA3
        Electron Transport Chain
    Oxidative phosphorylation

    4        Reactome Pathways for NDUFA3
        Respiratory electron transport
    Metabolism
    Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
    The citric acid (TCA) cycle and respiratory electron transport


    5/6         Kegg Pathways  (Kegg details for NDUFA3) (see all 6):
        Oxidative phosphorylation
    Metabolic pathways
    Non-alcoholic fatty liver disease (NAFLD)
    Alzheimer's disease
    Parkinson's disease


    NDUFA3 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NDUFA3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/55 Interacting proteins for NDUFA3 (ENSP000003982904) via UniProtKB, MINT, STRING, and/or I2D (see all 55)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NDUFC1ENSP000003777704STRING: ENSP00000377770 STRING: ENSP00000265500
    CYC1ENSP000003171594STRING: ENSP00000317159
    ENSG00000267059ENSP000002629464STRING: ENSP00000262946
    MT-CYBENSP000003545544STRING: ENSP00000354554
    MT-ND1ENSP000003546874STRING: ENSP00000354687
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006120mitochondrial electron transport, NADH to ubiquinone NAS9878551
    GO:0022904respiratory electron transport chain TAS--
    GO:0044237cellular metabolic process TAS--
    GO:0044281small molecule metabolic process TAS--

    NDUFA3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NDUFA3 (NDUA3)

    8 HMDB Compounds for NDUFA3    About this table
    CompoundSynonyms CAS #PubMed Ids
    FAD1H-Purin-6-amine flavin dinucleotide (see all 21)146-14-5--
    IronArmco iron (see all 19)7439-89-6--
    NAD3-Carbamoyl-1-D-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate (see all 28)53-84-9--
    NADH1,4-Dihydronicotinamide adenine dinucleotide (see all 17)58-68-4--
    QH2CoQH2 (see all 5)56275-39-9--
    SulfideSulfide (see all 4)18496-25-8--
    Ubiquinone Q1Coenzyme Q (see all 9)727-81-1--
    Ubiquinone Q22-(3,7-dimethyl-2,6-octadienyl)-5,6-dimethoxy-3-methyl-2,5-Cyclohexadiene-1,4-dione (see all 7)606-06-4--

    1 DrugBank Compound for NDUFA3    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    NADHbeta-DPNH (see all 18)606-68-8target--17139284 17016423

    Search CenterWatch for drugs/clinical trials and news about NDUFA3 / NDUA3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NDUFA3 gene: 
    NM_004542.3  

    Unigene Cluster for NDUFA3:

    NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa
    Hs.198269  [show with all ESTs]
    Unigene Representative Sequence: CD248715
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000417903(uc002qdf.3) ENST00000419113(uc002qde.3) ENST00000485876
    ENST00000391762 ENST00000471292 ENST00000451517 ENST00000391763 ENST00000391764
    ENST00000484103 ENST00000303553 ENST00000422029 ENST00000420296 ENST00000480713
    ENST00000482960

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    Additional mRNA sequence: 

    AF044955.1 AF070653.1 AK289489.1 BC011021.1 BC022369.1 BC061644.1 CR542143.1 

    14 DOTS entries:

    DT.447997  DT.97804952  DT.100735816  DT.121451717  DT.100785884  DT.95270160  DT.121451743  DT.86835744 
    DT.91967036  DT.121451833  DT.91837942  DT.95287028  DT.92428332  DT.95270166 

    24/160 AceView cDNA sequences (see all 160):

    AI342995 BC061644 AI814011 BC011021 F25043 AI885387 BE621354 AA255557 
    F31172 BF939295 AI253561 AI675759 AA970515 AA705897 AA813127 CA312034 
    AI148243 AW002081 F21180 AI362796 BU741250 AA255573 F26119 BM805609 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for NDUFA3    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4
    SP1:                                    
    SP2:                          -         


    ECgene alternative splicing isoforms for NDUFA3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NDUFA3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCCGACGTGC
    NDUFA3 Expression
    About this image


    See NDUFA3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NDUFA3

    SOURCE GeneReport for Unigene cluster: Hs.198269
        SABiosciences Expression via Pathway-Focused PCR Array including NDUFA3: 
              Mitochondrial Energy Metabolism in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NDUFA3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for NDUFA3 gene from 4/9 species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ndufa31 , 5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, more1, 5 82.14(n)1
    80.95(a)1
      7 (2.08 cM)5
    660911  NM_025348.21  NP_079624.11 
     36173735 
    lizard
    (Anolis carolinensis)
    Reptilia NDUFA36
    Uncharacterized protein
    68(a)
    1 ↔ 1
    GL343279.1(1534812-1536114)
    African clawed frog
    (Xenopus laevis)
    Amphibia BX855037.12   -- 77.15(n)    BX855037.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BI703424.12   -- 71.13(n)    BI703424.1 


    ENSEMBL Gene Tree for NDUFA3 (if available)
    TreeFam Gene Tree for NDUFA3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NDUFA3 gene

    NDUFA3 for paralogs           About GeneDecksing


    5/6 Pseudogenes.org Pseudogenes for NDUFA3 (see all 6)
    PGOHUM00000242346 PGOHUM00000248663 PGOHUM00000247270 PGOHUM00000249056 PGOHUM00000234718


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/114 SNPs in NDUFA3 are shown (see all 114)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0361754
    A breast cancer sample4--see VAR_0361752 N D mis40--------
    rs1890868751,2
    C--50920026(+) GGGGTA/GACTCA 1 -- us2k10--------
    rs1512012451,2
    --50920084(+) ATACCC/TGCTAG 1 -- us2k10--------
    rs2542591,2
    C,F,A,H--54606405(-) GCAAGG/AAGCGT 1 -- int128Minor allele frequency- A:0.49EA NS NA WA CSA EU 4586
    rs1139662691,2
    C--54606420(+) CCTTCA/G/TGGAGT 1 -- spa11CSA 1
    rs1129980241,2
    C--54606421(+) CTTCAA/C/GGAGTC 1 -- spa11CSA 1
    rs1506178091,2
    F--54606436(+) CCTTCC/ATCAAG 2 /I /L mis11Minor allele frequency- A:0.00NA 4538
    rs1387584391,2
    C,F--54606446(+) GAATGC/GCTGGG 2 A G mis11Minor allele frequency- G:0.00NA 4536
    rs1123647151,2
    C--54606497(+) CCTCGC/GTGCGT 1 -- spd11Minor allele frequency- G:0.00CSA 1
    rs1120590661,2
    C--54606534(+) GTCCAC/TCCCCG 1 -- int11Minor allele frequency- T:0.50WA 2

    HapMap Linkage Disequilibrium report for NDUFA3 (54606036 - 54612564 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for NDUFA3:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2718812CNV Deletion23290073
    nsv510773CNV Loss20534489
    nsv515623CNV Loss19592680
    nsv833877CNV Loss17160897
    dgv4001n71CNV Loss21882294
    nsv470157CNV Loss18288195

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 603832    OMIM disorders: --

    5 diseases for NDUFA3:    About MalaCards
    huntington's disease    chronic lymphocytic leukemia    parkinson's disease    leukemia
    alzheimer's disease


    NDUFA3 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): NDUFA3
    Human Genome Epidemiology (HuGE) Navigator: NDUFA3 (5 documents)

    Export disorders for NDUFA3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NDUFA3 gene, integrated from 9 sources (see all 16):
    (articles sorted by number of sources associating them with NDUFA3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed. (PubMed id 9878551)1, 2, 3 Loeffen J.L....Smeitink J.A. (1998)
    2. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
    3. Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. (PubMed id 19343046)1, 4 Saito A....Kamatani N. (2009)
    4. Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey. (PubMed id 18977241)1, 4 Starr J.M....Deary I.J. (2008)
    5. A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition. (PubMed id 17601350)1, 4 Harris S.E....Deary I.J. (2007)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification. (PubMed id 12611891)1, 2 Murray J.... Capaldi R.A. (2003)
    8. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (2000)
    9. Genetic association with overall survival of taxane-tr eated lung cancer patients - a genome-wide association study in human lymphoblas toid cell lines followed by a clinical association study. (PubMed id 23006423)1 Niu N....Wang L. (2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 4696 HGNC: 7686 AceView: NDUFA3 Ensembl:ENSG00000170906 euGenes: HUgn4696
    ECgene: NDUFA3 Kegg: 4696 H-InvDB: NDUFA3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NDUFA3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NDUFA3 gene:
    Search GeneIP for patents involving NDUFA3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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