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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

NDUFA2 Gene

protein-coding GIFtS: 57
GCID: GC05M140005

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa

(Previous names: NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2 (8kD,...)

Explore 8 diseases affiliated with
NDUFA2 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
NADH Dehydrogenase (Ubiquinone) 1 Alpha Subcomplex, 2, 8kDa¹ ²		NADH Dehydrogenase [Ubiquinone] 1 Alpha Subcomplex Subunit 2²
B8¹ ²		NADH-Ubiquinone Oxidoreductase Subunit CI-B8²
NADH Dehydrogenase (Ubiquinone) 1 Alpha Subcomplex, 2 (8kD, B8)¹		CI-B8³
CD14²		Complex I-B8³
CIB8²		NADH-Ubiquinone Oxidoreductase B8 Subunit³
Complex I B8 Subunit²

External Ids:	HGNC: 7685¹	Entrez Gene: 4695²	Ensembl: ENSG00000131495⁷	OMIM: 602137⁵	UniProtKB: O43678³

Export aliases for NDUFA2 gene to outside databases

Previous GC identifers: GC05M139841 GC05M140607 GC05M140008 GC05M140053 GC05M135170

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NDUFA2:

The encoded protein is a subunit of the hydrophobic protein fraction of the NADH:ubiquinone oxidoreductase (complex 1),

the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane, and may be

involved in regulating complex I activity or its assembly via assistance in redox processes. Mutations in this gene

are associated with Leigh syndrome, an early-onset progressive neurodegenerative disorder. Alternative splicing

results in multiple transcript variants.(provided by RefSeq, May 2010)

UniProtKB/Swiss-Prot: NDUA2_HUMAN, O43678

Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is

believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the

respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

Gene Wiki entry for NDUFA2

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000005.9 NC_018916.1 NT_029289.11

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the NDUFA2 gene promoter:
CREB ATF-2 deltaCREB c-Jun
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: NDUFA2 promoter sequence

Search SABiosciences Chromatin IP Primers for NDUFA2

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NDUFA2

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q31.2 Ensembl cytogenetic band: 5q31.3 HGNC cytogenetic band: 5q31.2

NDUFA2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NDUFA2 gene location

GeneLoc information about chromosome 5 GeneLoc Exon Structure

GeneLoc location for GC05M140005: view genomic region (about GC identifiers)

Start:	140,018,325 bp from pter	End:	140,027,370 bp from pter
Size:	9,046 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: NDUA2_HUMAN, O43678 (See protein sequence)

Recommended Name: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2

Size: 99 amino acids; 10922 Da

Subunit: Complex I is composed of 45 different subunits

Subcellular location: Mitochondrion inner membrane; Peripheral membrane protein; Matrix side

1 PDB 3D structure from and Proteopedia for NDUFA2:

1S3A (3D)

Secondary accessions: D6RJD6 Q6IAY8

Alternative splicing: 2 isoforms: O43678-1 O43678-2

Explore the universe of human proteins at neXtProt for NDUFA2: NX_O43678

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_O43678

NDUFA2 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001171941.1 NP_002479.1

ENSEMBL proteins:

ENSP00000252102 ENSP00000427220

Reactome Protein details: O43678
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Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005739	mitochondrion	--	--
GO:0005743	mitochondrial inner membrane	TAS	--
GO:0005747	mitochondrial respiratory chain complex I	NAS	9878551
GO:0031966	mitochondrial membrane	IDA	17209039

NDUFA2 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

NDUFA2 for domains About GeneDecksing

3 InterPro domains/families:

IPR016464 NADH_Ub_cplx-1_asu_su-2

IPR007741 Ribosome/NADH_DH

IPR012336 Thioredoxin-like_fold

Graphical View of Domain Structure for InterPro Entry O43678

ProtoNet protein and cluster: O43678

1 Blocks protein family: IPB007741 Mitochondrial ribosome

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: NDUA2_HUMAN, O43678

Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is

believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the

respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

Genatlas biochemistry entry for NDUFA2:

NADH ubiquinone oxidoreductase (Q reductase),8kDa,component alpha 2,hydrophobic fraction of the complex I multi-subunit

enzyme of the oxidative phosphorylation (OXPHOS)

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008137	NADH dehydrogenase (ubiquinone) activity	NAS	9878551

NDUFA2 for ontologies About GeneDecksing

Animal Models:

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NDUFA2

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.

8/9 pathways (see all 9)
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.	1.00	Parkinson's disease	0.61
Respiratory electron transport	0.81	Oxidative phosphorylation	0.52
Electron Transport Chain	0.76	Alzheimer's disease	0.43
The citric acid (TCA) cycle and respiratory electron transport	0.72	Huntington's disease	0.40

Metabolism

Metabolism

1.00

Metabolic pathways

0.38

Metformin Pathway, Pharmacodynamic

Metformin Pathway, Pharmacodynamic

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

2 BioSystems Pathways for NDUFA2

	Oxidative phosphorylation
	Electron Transport Chain

4 Reactome Pathways for NDUFA2

	Respiratory electron transport
	Metabolism
	Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
	The citric acid (TCA) cycle and respiratory electron transport

1 PharmGKB Pathway for NDUFA2

Metformin Pathway, Pharmacodynamic

5 Kegg Pathways (Kegg details for NDUFA2):

	Oxidative phosphorylation
	Metabolic pathways
	Alzheimer's disease
	Parkinson's disease
	Huntington's disease

NDUFA2 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for NDUFA2

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/61 Interacting proteins for NDUFA2 (O43678^{2, 3} ENSP00000252102⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 61)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
HMP19	Q9Y328²^,³, ENSP00000307722⁴	MINT-8263588 I2D: score=2 STRING: ENSP00000307722
MT-ND1	P03886³, ENSP00000354687⁴	I2D: score=1 STRING: ENSP00000354687
MT-ND4	P03905³, ENSP00000354961⁴	I2D: score=1 STRING: ENSP00000354961
NDUFA5	Q16718³, ENSP00000347988⁴	I2D: score=1 STRING: ENSP00000347988
NDUFB3	O43676³, ENSP00000237889⁴	I2D: score=1 STRING: ENSP00000237889

About this table

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006120	mitochondrial electron transport, NADH to ubiquinone	NAS	9878551
GO:0022904	respiratory electron transport chain	TAS	--
GO:0044281	small molecule metabolic process	TAS	--

NDUFA2 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for NDUFA2

8 HMDB Compounds for NDUFA2 About this table

Compound	Synonyms	CAS #	PubMed Ids
FAD	1H-Purin-6-amine flavin dinucleotide (see all 21)	146-14-5	--
Iron	Armco iron (see all 19)	7439-89-6	--
NAD	3-Carbamoyl-1-D-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate (see all 28)	53-84-9	--
NADH	1,4-Dihydronicotinamide adenine dinucleotide (see all 17)	58-68-4	--
QH2	CoQH2 (see all 5)	56275-39-9	--
Sulfide	Sulfide (see all 4)	18496-25-8	--
Ubiquinone Q1	Coenzyme Q (see all 9)	727-81-1	--
Ubiquinone Q2	2-(3,7-dimethyl-2,6-octadienyl)-5,6-dimethoxy-3-methyl-2,5-Cyclohexadiene-1,4-dione (see all 7)	606-06-4	--

1 DrugBank Compound for NDUFA2 About this table

Compound	Synonyms	CAS #	Type	Actions	PubMed Ids
NADH	beta-DPNH (see all 18)	606-68-8	target	--	17139284 17016423

Search CenterWatch for drugs/clinical trials and news about NDUFA2 / NDUA2

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for NDUFA2 gene (2 alternative transcripts):

NM_001185012.1 NM_002488.4

Unigene Cluster for NDUFA2:

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa

Hs.75914 [show with all ESTs]

Unigene Representative Sequence: BF686835

4 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000510680 ENST00000252102(uc021yem.1 uc003lgp.3) ENST00000512088

ENST00000502960

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Additional cDNA sequence:

AF047185.1 AF077029.1 BC003674.1 CR457016.1 NR_033697.1

14 DOTS entries:

DT.454420 DT.100839133 DT.95170442 DT.120833481 DT.92459893 DT.120833483 DT.95170441 DT.75193702

DT.100839139 DT.95170437 DT.100758886 DT.101955157 DT.120833427 DT.91979006

1 AceView cDNA sequence:

W96226

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

NDUFA2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

NDUFA2 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Ovary

Primary Follicle

Primary Oocyte

Female Gametocytes, Germ Cells

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See NDUFA2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NDUFA2

SOURCE GeneReport for Unigene cluster: Hs.75914

SABiosciences Expression via Pathway-Focused PCR Array including NDUFA2:

Mitochondrial Energy Metabolism in human mouse rat

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for NDUFA2 gene from 8/24 species (see all 24) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Ndufa2^{1 , 5}	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, more^{1, 5}	83.5(n)¹ 85.86(a)¹		18 (19.46 cM)⁵ 17991¹ NM_010885.4¹ NP_035015.2¹ 36742332⁵
chicken (Gallus gallus)	Aves	NDUFA2¹	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, more	71.87(n) 66.67(a)		768860 XM_001232015.2 XP_001232016.1
lizard (Anolis carolinensis)	Reptilia	NDUFA2⁶	--	72(a)	1 ↔ 1	4(77812733-77816096)
zebrafish (Danio rerio)	Actinopterygii	ndufa2¹	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, more	68.71(n) 67.35(a)		554125 NM_001024420.1 NP_001019591.1
fruit fly (Drosophila melanogaster)	Insecta	CG15434¹	CG15434	57.38(n) 50.63(a)		50178 NM_144084.2 NP_652341.1
worm (Caenorhabditis elegans)	Secernentea	Y63D3A.7⁶	Protein Y63D3A.7	49(a)	1 ↔ 1	I(14113624-14114079)
thale cress (Arabidopsis thaliana)	eudicotyledons	AT5G47890¹	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex more	51.59(n) 52.38(a)		834840 NM_124163.4 NP_199600.1
rice (Oryza sativa)	Liliopsida	Os04g0310500¹	hypothetical protein	62.08(n) 47.5(a)		4335450 NM_001058970.2 NP_001052435.2

ENSEMBL Gene Tree for NDUFA2 (if available)
TreeFam Gene Tree for NDUFA2 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for NDUFA2 gene

NDUFA2 for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for NDUFA2
PGOHUM00000239570

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 5 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs60313457^1,2	C	--	135170317(+)	`CTTTAT/CGAGGA`	3	--	ut3¹ nc-transcript-variant		2		WA	120
rs60115373^1,2	C,F	--	140024491(+)	`GGAGTG/AGGCTG`	4	--	ds500¹ int¹		10		WA NA CSA EA	369
rs181090389^1,2	C	--	140024706(+)	`ACTCAC/TTCCCC`	4	--	ut3¹ ds500¹		0	--	--	--	--
rs185138818^1,2		--	140024784(+)	`ATGTTC/TTCTGC`	4	--	ds500¹ ut3¹		0	--	--	--	--
rs189556993^1,2		--	140024915(+)	`GCCCCC/TCCGCC`	4	--	ut3¹ ds500¹		0	--	--	--	--
rs184064335^1,2		--	140024961(+)	`GATGAA/GACAGA`	4	--	ut3¹ nc-transcript-variant		0	--	--	--	--
rs150344402^1,2		--	140025027(+)	`GTAGAA/GGGTAG`	4	--	ut3¹ nc-transcript-variantint¹		0	--	--	--	--
rs200966132^1,2		--	140025166(+)	`CAGTGC/GAGGCT`	4	--	ut3¹ nc-transcript-variantint¹		0	--	--	--	--
rs142478462^1,2	C	--	140025192(+)	`TAGAAC/TGTTCT`	5	I V	int¹ nc-transcript-variantut3¹ mis¹		1		NA	4550
rs138059203^1,2	C,F	--	140025241(+)	`AAAGGG/AACATT`	5	/V	nc-transcript-variantint¹ ut3¹ syn¹		1		NA	4550

HapMap Linkage Disequilibrium report for NDUFA2 (140018325 - 140027370 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for NDUFA2: --
Human Gene Mutation Database (HGMD): NDUFA2

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

NDUFA2 for disorders           About GeneDecksing

OMIM gene information: 602137
OMIM disorders: 256000
8 diseases for NDUFA2:    About MalaCards

leigh syndrome due to mitochondrial complex i deficiency mitochondrial complex i deficiency multiple cranial nerve palsy cranial nerve palsy

leigh disease leptospirosis huntington's disease parkinson's disease

1 disease from the University of Copenhagen DISEASES database for NDUFA2:

Anemia

Human Genome Epidemiology (HuGE) Navigator: NDUFA2 (2 documents)

Export disorders for NDUFA2 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for NDUFA2 gene, integrated from 9 sources (see all 30):
(articles sorted by number of sources associating them with NDUFA2)

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world of online information

Identification and primary structure of five human NADH-ubiquinone oxidoreductase subunits. (PubMed id 9425316)^{1, 2, 3} Ton C....Liew C.C. (1997)
The oxidized subunit B8 from human complex I adopts a thioredoxin fold. (PubMed id 15341729)^{1, 2, 9} Brockmann C....Oschkinat H. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification. (PubMed id 12611891)^{1, 2} Murray J.... Capaldi R.A. (2003)
Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)^{1, 2} Zhang Q.-H.... Chen Z. (2000)
Mapping of the NDUFA2, NDUFA6, NDUFA7, NDUFB8, and NDUFS8 electron transport chain genes by intron based radiation hybrid mapping. (PubMed id 9763676)^{1, 3} Emahazion T. and Brookes A.J. (1998)
A census of human soluble protein complexes. (PubMed id 22939629)¹ Havugimana P.C....Emili A. (2012)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)
A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)¹ Vinayagam A....Wanker E.E. (2011)
Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)¹ OlA!h J....OvA!di J. (2011)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 4695	HGNC: 7685	AceView: NDUFA2.2	Ensembl:ENSG00000131495	euGenes: HUgn4695
ECgene: NDUFA2	Kegg: 4695	H-InvDB: NDUFA2

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for NDUFA2	Pharmacogenomics, SNPs, Pathways

Intellectual Property for NDUFA2 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for NDUFA2 gene:
Search GeneIP for patents involving NDUFA2

GeneCards and IP:
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NDUFA2 Gene

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa

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NDUFA2 Gene

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa

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