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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

NDST3 Gene

protein-coding GIFtS: 54
GCID: GC04P118954

N-deacetylase/N-sulfotransferase (heparan glucosaminyl)...

Explore 4 diseases affiliated with
NDST3 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 3¹ ²		N-Heparan Sulfate Sulfotransferase 3² ³
HSST3¹ ² ³		N-HSST 3² ³
Glucosaminyl N-Deacetylase/N-Sulfotransferase 3² ³		Bifunctional Heparan Sulfate N-Deacetylase/N-Sulfotransferase 3²
NDST-3² ³		GlcNAc N-Deacetylase/ N-Sulfotransferase 3²
HNDST-3¹		EC 2.8.2.8³

External Ids:	HGNC: 7682¹	Entrez Gene: 9348²	Ensembl: ENSG00000164100⁷	OMIM: 603950⁵	UniProtKB: O95803³

Export aliases for NDST3 gene to outside databases

Previous GC identifers: GC04P119708 GC04P119236 GC04P119348 GC04P119414 GC04P119313 GC04P114690

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NDST3:

This gene encodes a member of the heparan sulfate/heparin GlcNAc N-deacetylase/ N-sulfotransferase family. The encoded

enzyme is a type II transmembrane protein that resides in the Golgi apparatus. This monomeric bifunctional enzyme

catalyzes the N-deacetylation and N-sulfation of N-acetylglucosamine residues in heparan sulfate and heparin, which

are the initial chemical modifications required for the biosynthesis of the functional oligosaccharide sequences that

define the specific ligand binding activities of heparan sulfate and heparin. (provided by RefSeq, Nov 2008)

UniProtKB/Swiss-Prot: NDST3_HUMAN, O95803

Function: Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine

(GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone

to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Has high

deacetylase activity but low sulfotransferase activity

Gene Wiki entry for NDST3

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000004.11 NC_018915.1 NT_016354.19

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the NDST3 gene promoter:
LHX3b/Lhx3b AP-1 AML1a GCNF Pax-2 Pax-2a GCNF-1 LHX3a/Lhx3a FOXJ2 GCNF-2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: NDST3 promoter sequence

Search SABiosciences Chromatin IP Primers for NDST3

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NDST3

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q26 Ensembl cytogenetic band: 4q26 HGNC cytogenetic band: 4q26

NDST3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NDST3 gene location

GeneLoc information about chromosome 4 GeneLoc Exon Structure

GeneLoc location for GC04P118954: view genomic region (about GC identifiers)

Start:	118,954,773 bp from pter	End:	119,179,803 bp from pter
Size:	225,031 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: NDST3_HUMAN, O95803 (See protein sequence)

Recommended Name: Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3

Size: 873 amino acids; 100902 Da

Subunit: Monomer (By similarity)

Subcellular location: Golgi apparatus membrane; Single-pass type II membrane protein (By similarity)

Miscellaneous: The presence of 4 different heparan sulfate N-deacetylase/N-sulfotransferase enzymes in mammals, as well

as differences in their enzyme activity suggest that some initiate heparan sulfate modification/sulfation reactions,

whereas other later on fill in or extend already modified heparan sulfate sequences

Secondary accessions: Q4W5C1 Q4W5D0 Q6UWC5 Q9UP21

Alternative splicing: 2 isoforms: O95803-1 O95803-2 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NDST3: NX_O95803

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_O95803

NDST3 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_004775.1

ENSEMBL proteins:

ENSP00000296499 ENSP00000396625

Reactome Protein details: O95803
Human Recombinant Protein Products for NDST3:

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	Uscn Proteins for NDST3

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000139	Golgi membrane	IEA	--
GO:0016021	integral to membrane	IEA	--

NDST3 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

NDST3 for domains About GeneDecksing

2 InterPro domains/families:

IPR021930 Heparan_SO4_deacetylase

IPR000863 Sulfotransferase_dom

Graphical View of Domain Structure for InterPro Entry O95803

ProtoNet protein and cluster: O95803

UniProtKB/Swiss-Prot: NDST3_HUMAN, O95803

Similarity: Belongs to the sulfotransferase 1 family. NDST subfamily

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: NDST3_HUMAN, O95803

Function: Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine

(GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone

to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Has high

deacetylase activity but low sulfotransferase activity

Catalytic activity: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate +

[heparan sulfate]-N-sulfoglucosamine

Enzyme Number (IUBMB): EC 2.8.2.8¹

Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008146	sulfotransferase activity	--	--
GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity	IEA	--
GO:0016787	hydrolase activity	--	--
GO:0019213	deacetylase activity	IEA	--

NDST3 for ontologies About GeneDecksing

Phenotypes:
3 GenomeRNAi human phenotypes for NDST3:

Decreased Wnt reporter activit

Elongated cells with protrusio

Synthetic lethal with Ras

12 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Ndst3):

behavior/neurological	cellular	craniofacial	digestive/alimentary	embryogenesis
hematopoietic system	homeostasis/metabolism	immune system	mortality/aging	nervous system
skeleton	vision/eye

NDST3 for phenotypes About GeneDecksing

Animal Models:
Mouse knock-out Ndst3^tm1.1Grob for NDST3

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for NDST3

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		hsa-miR-579 hsa-miR-361-5p hsa-miR-3194-5p hsa-let-7d hsa-miR-1197 hsa-miR-199a-3p hsa-let-7g hsa-miR-629*

		SwitchGear 3'UTR luciferase reporter plasmid: NDST3 3' UTR sequence

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NDST3

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

MPS IIIC - Sanfilippo syndrome C

8/16 pathways (see all 16)
MPS VI - Maroteaux-Lamy syndrome	1.00	MPS IIIA - Sanfilippo syndrome A	1.00
MPS IIIC - Sanfilippo syndrome C	1.00	MPS IIID - Sanfilippo syndrome D	1.00
MPS I - Hurler syndrome	1.00	MPS IX - Natowicz syndrome	1.00
Mucopolysaccharidoses	1.00	MPS II - Hunter syndrome	1.00

heparan sulfate biosynthesis

	heparan sulfate biosynthesis	1.00			heparan sulfate biosynthesis (late stages)	0.78
	Glycosaminoglycan biosynthesis - heparan sulfate	0.83

Metabolism

Metabolism

1.00

Metabolic pathways

0.38

Disease

Disease

1.00

Biological oxidations

metapathway biotransformation

0.41

Pathway sources
See GeneCards unified pathways
Show all pathways

3 BioSystems Pathways for NDST3

	heparan sulfate biosynthesis (late stages)
	heparan sulfate biosynthesis
	metapathway biotransformation

5/18 Reactome Pathways for NDST3 (see all 18)

	MPS VI - Maroteaux-Lamy syndrome
	Metabolism
	Disease
	HS-GAG biosynthesis
	MPS II - Hunter syndrome

2 Kegg Pathways (Kegg details for NDST3):

	Glycosaminoglycan biosynthesis - heparan sulfate
	Metabolic pathways

UniProtKB/Swiss-Prot: NDST3_HUMAN, O95803

Pathway: Glycan metabolism; heparan sulfate biosynthesis

Pathway: Glycan metabolism; heparin biosynthesis

NDST3 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for NDST3

STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

5/10 Interacting proteins for NDST3 (ENSP00000296499⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 10)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
EXT1	ENSP00000367446⁴	STRING: ENSP00000367446
EXT2	ENSP00000342656⁴	STRING: ENSP00000342656
HS3ST1	ENSP00000002596⁴	STRING: ENSP00000002596
HS3ST2	ENSP00000261374⁴	STRING: ENSP00000261374
HS3ST3A1	ENSP00000284110⁴	STRING: ENSP00000284110

About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0015012	heparan sulfate proteoglycan biosynthetic process	IEA	--
GO:0030210	heparin biosynthetic process	IEA	--

NDST3 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for NDST3
Search CenterWatch for drugs/clinical trials and news about NDST3

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for NDST3 gene:

NM_004784.2

Unigene Cluster for NDST3:

N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3

Hs.480596 [show with all ESTs]

Unigene Representative Sequence: NM_004784

3 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000394488(uc003ibw.3) ENST00000296499(uc011cgf.1 uc003ibx.3)

ENST00000433996

miRNA Products:		OriGene 3'-UTR Clone: NDST3 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NDST3
		8/59 QIAGEN miScript miRNA Assays for microRNAs that regulate NDST3 (see all 59):
		hsa-miR-579 hsa-miR-361-5p hsa-miR-3194-5p hsa-let-7d hsa-miR-1197 hsa-miR-199a-3p hsa-let-7g hsa-miR-629*

		SwitchGear 3'UTR luciferase reporter plasmid: NDST3 3' UTR sequence

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Additional cDNA sequence:

AF074924.1 AF076605.1 AK295439.1 AY358852.1 BC034037.1 BC109309.1 BC109310.1 HQ234312.1

2 DOTS entries:

DT.209371 DT.101959150

1 AceView cDNA sequence:

AA354508

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

NDST3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTACCTCATA

About this image

NDST3 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 2 LifeMap Cells

Name

Category

PureStem™ mesenchymal progenitor SM30 (Embryonic Progenitor Cell)

Adipose, Bone, Cartilage

PureStem™ mesenchymal progenitor 7SMOO32 (Embryonic Progenitor Cell)

Adipose, Bone, Cartilage

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See NDST3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NDST3

SOURCE GeneReport for Unigene cluster: Hs.480596

UniProtKB/Swiss-Prot: NDST3_HUMAN, O95803

Tissue specificity: Expressed in brain, kidney, liver, fetal and adult lung, adult pancreas, placenta, fetal spleen and

fetal thymus. Not detected in adult/ fetal heart and skeletal muscle

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In Situ
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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for NDST3 gene from 3/16 species (see all 16) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	NDST3¹	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) more	81.94(n) 90.38(a)		428769 XM_426325.2 XP_426325.2
zebrafish (Danio rerio)	Actinopterygii	ndst3⁶	N-deacetylase/N-sulfotransferase (heparan glucosam...	75(a)	1 → many	1(18885370-19054531)
fruit fly (Drosophila melanogaster)	Insecta	sfl³	cell surface receptor linked signal transduction more	58(a)		--

ENSEMBL Gene Tree for NDST3 (if available)
TreeFam Gene Tree for NDST3 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for NDST3 gene

HS3ST2² HS3ST1² NDST2² HS3ST3B1² HS3ST4² HS3ST6² HS3ST3A1² HS3ST5²

NDST1² NDST4²

4 SIMAP similar genes for NDST3 using alignment to 2 protein entries: NDST3_HUMAN (see all proteins):

NDST4 NDST2 NDST1 HS3ST1

NDST3 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 4 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs11335648^1,2	C,F	--	114764209(+)	`TAAATA/-AGATA`	1	--	int¹		2		NA	4
rs184626359^1,2		--	118953726(+)	`TAGAAC/TTTATT`	1	--	us2k¹		0	--	--	--	--
rs6534077^1,2	C,A,H	--	118953737(+)	`TCAGCC/TACAGC`	1	--	us2k¹		12		NA WA CSA EA	377
rs189289011^1,2		--	118953746(+)	`GCTCGA/TTTCCA`	1	--	us2k¹		0	--	--	--	--
rs181958575^1,2		--	118953778(+)	`GTTTCA/TCTTTT`	1	--	us2k¹		0	--	--	--	--
rs142134724^1,2		--	118953790(+)	`TCCAAC/TTCTCA`	1	--	us2k¹		0	--	--	--	--
rs113786811^1,2	C	--	118953808(+)	`CTTCC-/TGAG TATCA`	1	--	us2k¹		1		CSA	2
rs184445782^1,2		--	118953829(+)	`TTTCAC/GACTTC`	1	--	us2k¹		0	--	--	--	--
rs6534078^1,2	C,F,A,H	--	118953901(+)	`AGAGGG/AAGGAA`	1	--	us2k¹ trp³		23		NS EA NA WA CSA	2347
rs115453549^1,2	F	--	118953929(+)	`TGGTGG/TTTTTT`	1	--	us2k¹		1		WA	118

HapMap Linkage Disequilibrium report for NDST3 (118954773 - 119179803 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 15 variations for NDST3
14 CNVs: 32637 47878 2542 59165 6311 3511 36188 8453 63939 36189 92340 80446 32636 92339
1 Indel: 27427

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

NDST3 for disorders           About GeneDecksing

OMIM gene information: 603950    OMIM disorders: --

4 diseases for NDST3:    About MalaCards

mast cell neoplasm alcohol dependence hermaphroditism alcoholism

1 disease from the University of Copenhagen DISEASES database for NDST3:

Mast cell neoplasm

Human Genome Epidemiology (HuGE) Navigator: NDST3 (3 documents)

Export disorders for NDST3 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for NDST3 gene, integrated from 9 sources (see all 17):
(articles sorted by number of sources associating them with NDST3)

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Molecular cloning and expression of a third member of the heparan sulfate/heparin GlcNAc N-deacetylase/ N-sulfotransferase family. (PubMed id 9915799)^{1, 2, 3} Aikawa J. and Esko J.D. (1999)
Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)^{1, 2} Hillier L.W....Wilson R.K. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)^{1, 2} Clark H.F.... Gray A.M. (2003)
Multiple isozymes of heparan sulfate/heparin GlcNAc N- deacetylase/GlcN N-sulfotransferase. Structure and activity of the fourth member, NDST4. (PubMed id 11087757)^{1, 9} Aikawa J.... Esko J.D. (2001)
Post-transcriptional exon shuffling events in humans can be evolutionarily conserved and abundant. (PubMed id 21948523)¹ Al-Balool H.H....Jackson M.S. (2011)
A systematic gene-based screen of chr4q22-q32 identif ies association of a novel susceptibility gene, DKK2, with the quantitative tra it of alcohol dependence symptom counts. (PubMed id 20332099)¹ Kalsi G....Riley B.P. (2010)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
Genome-wide searching of rare genetic variants in WTC CC data. (PubMed id 20549515)¹ Feng T. and Zhu X. (2010)
Glycanogenomics: a qPCR-approach to investigate biological glycan function. (PubMed id 18692483)¹ Krenn E.C....Kungl A.J. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 9348	HGNC: 7682	AceView: NDST3.2	Ensembl:ENSG00000164100	euGenes: HUgn9348
ECgene: NDST3	Kegg: 9348	H-InvDB: NDST3

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for NDST3	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for NDST3	Genetics and Cytogenetics in Oncology and Haematology
GGDB	http://riodb.ibase.aist.go.jp/rcmg/ggdb/

Intellectual Property for NDST3 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for NDST3 gene:
Search GeneIP for patents involving NDST3

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