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NDRG3 Gene

protein-coding   GIFtS: 51
GCID: GC20M035280

NDRG Family Member 3

  See NDRG3-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
NDRG Family Member 31 2
N-Myc Downstream-Regulated Gene 3 Protein2 3
Protein NDRG32

External Ids:    HGNC: 144621   Entrez Gene: 574462   Ensembl: ENSG000001010797   OMIM: 6052735   UniProtKB: Q9UGV23   

Export aliases for NDRG3 gene to outside databases

Previous GC identifers: GC20M035008 GC20M035918 GC20M035965 GC20M034713 GC20M032016


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for NDRG3 Gene:
NDRG3 (NDRG family member 3) is a protein-coding gene. Diseases associated with NDRG3 include motor peripheral neuropathy. An important paralog of this gene is NDRG4.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000020.10  NT_011362.11  NC_018931.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the NDRG3 gene promoter:
         MEF-2   Pax-6   HNF-3beta   LCR-F1   C/EBPalpha   E47   MEF-2A   Hand1   ARP-1   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNDRG3 promoter sequence
   Search Chromatin IP Primers for NDRG3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NDRG3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q11.21-q11.23   Ensembl cytogenetic band:  20q11.23   HGNC cytogenetic band: 20q11.21-q11.23

NDRG3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NDRG3 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20M035280:  view genomic region     (about GC identifiers)

Start:
35,280,169 bp from pter      End:
35,374,541 bp from pter
Size:
94,373 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: NDRG3_HUMAN, Q9UGV2 (See protein sequence)
Recommended Name: Protein NDRG3  
Size: 375 amino acids; 41409 Da
Secondary accessions: A2A2S8 E1P5U7 E1P5U8 Q5TH32 Q96PL8 Q96SM2 Q9BXY7 Q9H3N7 Q9H411 Q9H8J6
Alternative splicing: 3 isoforms:  Q9UGV2-1   Q9UGV2-2   Q9UGV2-3   

Explore the universe of human proteins at neXtProt for NDRG3: NX_Q9UGV2

Explore proteomics data for NDRG3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See NDRG3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_071922.2  NP_114402.1  

    ENSEMBL proteins: 
     ENSP00000362909   ENSP00000352703   ENSP00000345292   ENSP00000416636   ENSP00000442813  
     ENSP00000362878  

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    Cloud-Clone Corp. Proteins for NDRG3

     
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    antibodies-online proteins for NDRG3 (5 products) 

     
    antibodies-online peptides for NDRG3

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    antibodies-online antibodies for NDRG3 (31 products) 

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    antibodies-online kits for NDRG3 (8 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR004142 Ndr

    Graphical View of Domain Structure for InterPro Entry Q9UGV2

    ProtoNet protein and cluster: Q9UGV2

    1 Blocks protein domain: IPB004142 Ndr family

    UniProtKB/Swiss-Prot: NDRG3_HUMAN, Q9UGV2
    Similarity: Belongs to the NDRG family


    Find genes that share domains with NDRG3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
         
    Find genes that share ontologies with NDRG3           About GenesLikeMe


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Ndrg3):
     mortality/aging 

    Find genes that share phenotypes with NDRG3           About GenesLikeMe

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for NDRG3

    miRNA
    Products:
        
    miRTarBase miRNAs that target NDRG3:
    hsa-mir-92a-3p (MIRT049545), hsa-mir-1226-3p (MIRT036450)

    Block miRNA regulation of human, mouse, rat NDRG3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NDRG3 (see all 42):
    hsa-miR-194* hsa-miR-21* hsa-miR-4291 hsa-miR-140-5p hsa-miR-3607-3p hsa-miR-765 hsa-miR-759 hsa-miR-298
    SwitchGear 3'UTR luciferase reporter plasmidNDRG3 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for NDRG3
    Predesigned siRNA for gene silencing in human, mouse, rat NDRG3

    Gene Editing
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NDRG3

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    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NDRG3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    cytoskeleton1
    peroxisome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA11936845
    GO:0070062extracellular vesicular exosome IDA19056867

    Find genes that share ontologies with NDRG3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for NDRG3 About    
    See pathways by source

    SuperPathContained pathways About
    1PI3K / Akt Signaling
    PI3K / Akt Signaling
    2Apoptosis and Autophagy
    Apoptosis and Autophagy
    3Angiogenesis (CST)
    Angiogenesis


    Find genes that share SuperPaths with NDRG3           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    3 Cell Signaling Technology (CST) Pathways for NDRG3
        Apoptosis and Autophagy
    Angiogenesis
    PI3K / Akt Signaling



        Pathway & Disease-focused RT2 Profiler PCR Array including NDRG3: 
              Prostate Cancer in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for NDRG3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    Selected Interacting proteins for NDRG3 (Q9UGV23 ENSP000003452924) via UniProtKB, MINT, STRING, and/or I2D (see all 12)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DNAJB4Q9UDY43I2D: score=1 
    GLRA3O753113I2D: score=1 
    MTHFSDQ2M2963I2D: score=1 
    PPIFP304053I2D: score=1 
    SPENQ96T583I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007283spermatogenesis NAS11406283
    GO:0030154cell differentiation NAS11406283
    GO:0030308negative regulation of cell growth NAS11406283

    Find genes that share ontologies with NDRG3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NDRG3



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for NDRG3 gene (2 alternative transcripts): 
    NM_022477.3  NM_032013.3  

    Unigene Cluster for NDRG3:

    NDRG family member 3
    Hs.437338  [show with all ESTs]
    Unigene Representative Sequence: AK128068
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000373803 ENST00000359675 ENST00000349004(uc002xfw.3 uc002xfx.3 uc010zvq.2 uc010zvr.2)
    ENST00000422536 ENST00000540765 ENST00000373773
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat NDRG3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NDRG3 (see all 42):
    hsa-miR-194* hsa-miR-21* hsa-miR-4291 hsa-miR-140-5p hsa-miR-3607-3p hsa-miR-765 hsa-miR-759 hsa-miR-298
    SwitchGear 3'UTR luciferase reporter plasmidNDRG3 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for NDRG3
    Predesigned siRNA for gene silencing in human, mouse, rat NDRG3
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    GenScript: all cDNA clones in your preferred vector (see all 2): NDRG3 (NM_022477)
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    Primer
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    OriGene qPCR primer pairs and template standards for NDRG3
    OriGene qSTAR qPCR primer pairs in human, mouse for NDRG3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NDRG3
      QuantiTect SYBR Green Assays in human, mouse, rat NDRG3
      QuantiFast Probe-based Assays in human, mouse, rat NDRG3

    Additional mRNA sequence: 

    AB044943.1 AF308609.1 AK023618.1 AK027665.1 AK128068.1 AK295420.1 AK295466.1 BC136489.1 
    BC144169.1 NR_038370.1 

    10 DOTS entries:

    DT.95086156  DT.92475313  DT.101980321  DT.92475441  DT.100647967  DT.100794465  DT.100794474  DT.97847328 
    DT.120833203  DT.97847330 

    Selected AceView cDNA sequences (see all 197):

    BP432399 BQ020733 AI659189 AA311302 AI027140 BM663661 AI637519 CA420077 
    BM821220 BM693284 AI435981 AU132685 T33083 F12132 AI972307 NM_032013 
    AK023618 BM791796 BU177085 BQ640166 AI686167 BX951987 AB044943 BU726185 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NDRG3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCTACTGTTA
    NDRG3 Expression
    About this image


    NDRG3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Cerebellum
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
     
     Liver (Hepatobiliary System)
             Hepatocytes Liver Lobule
    NDRG3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NDRG3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.437338

    UniProtKB/Swiss-Prot: NDRG3_HUMAN, Q9UGV2
    Tissue specificity: Ubiquitous. Highly expressed in brain

        Pathway & Disease-focused RT2 Profiler PCR Array including NDRG3: 
              Prostate Cancer in human mouse rat

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for NDRG3 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ndrg31 , 5 N-myc downstream regulated gene 31, 5 89.96(n)1
    96(a)1
      2 (77.89 cM)5
    298121  NM_013865.21  NP_038893.11 
     1569273455 
    chicken
    (Gallus gallus)
    Aves NDRG36
    NDRG family member 3
    81(a)
    1 ↔ 1
    20(835504-867279)
    lizard
    (Anolis carolinensis)
    Reptilia NDRG36
    NDRG family member 3
    82(a)
    1 ↔ 1
    4(134696351-134730964)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.176642 Xenopus laevis transcribed sequence with moderate similarity to protein refNP_114402.1 (H.sapiens) NDRG family member 3; N-myc downstream-regulated gene 3; hypothetical protein FLJ13556 similar to N-myc downstream regulated 3 [Homo sapiens] less 76.82(n)    CA794198.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BC044139.12   -- 75.57(n)   327395  BC044139.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta MESK21 Misexpression suppressor of KSR 2 51.89(n)
    43.37(a)
      37451  NM_166454.2  NP_726076.1 
    worm
    (Caenorhabditis elegans)
    Secernentea Y48G10A.31 Y48G10A.3 47.68(n)
    34.77(a)
      173217  NM_060968.4  NP_493369.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons NDL11 NDL1 45.26(n)
    33.58(a)
      835777  NM_125058.2  NP_200486.1 
    rice
    (Oryza sativa)
    Liliopsida Os06g05630001 Os06g0563000 46.36(n)
    34.05(a)
      4341312  NM_001064413.1  NP_001057878.1 


    ENSEMBL Gene Tree for NDRG3 (if available)
    TreeFam Gene Tree for NDRG3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for NDRG3 gene
    NDRG42  NDRG22  NDRG12  
    4 SIMAP similar genes for NDRG3 using alignment to 6 protein entries:     NDRG3_HUMAN (see all proteins):
    NDRG1    TRG14    NDRG4    NDRG2

    Find genes that share paralogs with NDRG3           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NDRG3 (see all 1838)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1390576511,2
    --35279703(+) GCACTC/TGGTCT 3 -- int10--------
    rs1415703351,2
    --35279726(+) GATGGA/GTACAA 3 -- int10--------
    rs60285731,2
    C,H--35279827(+) ACACAG/AGTGGT 3 -- int14Minor allele frequency- A:0.00NS EA 398
    rs1875431811,2
    --35279844(+) GTGACA/GTGGAC 3 -- int10--------
    rs1154712601,2
    F--35279856(+) ACCTTC/ATCAAG 3 -- int11Minor allele frequency- A:0.01WA 118
    rs61016401,2
    F,H--35279894(+) ACAACA/GCTGTC 3 -- int14Minor allele frequency- G:0.01NS EA 416
    rs1470314431,2
    --35280079(+) AATCAC/TATGTG 3 -- int10--------
    rs1170107291,2
    C,F--35280118(+) CAACTC/TGGTCC 3 -- int11Minor allele frequency- T:0.04NA 120
    rs790198851,2
    C,F--35280156(+) AAGAAA/GTAACA 3 -- int11Minor allele frequency- G:0.03NA 120
    rs1481241711,2
    --35280226(+) TACTCC/TGGCAG 3 -- ut31 nc-transcript-variant0--------

    HapMap Linkage Disequilibrium report for NDRG3 (35280169 - 35374541 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for NDRG3:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2722379CNV Deletion23290073
    esv2722380CNV Deletion23290073
    esv2722377CNV Deletion23290073
    esv2722378CNV Deletion23290073
    esv992784CNV Insertion20482838
    nsv833967CNV Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NDRG3
    DNA2.0 Custom Variant and Variant Library Synthesis for NDRG3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 605273    OMIM disorders: --

    1 disease for NDRG3:    
    About MalaCards
    motor peripheral neuropathy

    1 disease from the University of Copenhagen DISEASES database for NDRG3:
    Motor peripheral neuropathy

    Find genes that share disorders with NDRG3           About GenesLikeMe


    Export disorders for NDRG3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NDRG3 gene, integrated from 10 sources (see all 27):
    (articles sorted by number of sources associating them with NDRG3)
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    1. Characterization and expression of three novel differentiation- related genes belong to the human NDRG gene family. (PubMed id 11936845)1, 2, 9 Qu X.... He F. (Mol. Cell. Biochem. 2002)
    2. Characterization of the human NDRG gene family: a newly identified member, NDRG4, is specifically expressed in brain and heart. (PubMed id 11352569)1, 2, 9 Zhou R.-H.... Miyata T. (Genomics 2001)
    3. Differential expression patterns of NDRG family proteins in the central nervous system. (PubMed id 17998568)1, 3 Okuda T....Miyata T. (J. Histochem. Cytochem. 2008)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (Nature 2001)
    6. N-myc downstream-regulated gene 1 is mutated in hereditary motor and sensory neuropathy-Lom. (PubMed id 10831399)1, 3 Kalaydjieva L.... Thomas P.K. (Am. J. Hum. Genet. 2000)
    7. Cloning and expression pattern of the human NDRG3 gene. (PubMed id 11406283)1, 9 Zhao W....Mao Y. (Biochim. Biophys. Acta 2001)
    8. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    9. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    10. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 57446 HGNC: 14462 AceView: NDRG3 Ensembl:ENSG00000101079 euGenes: HUgn57446
    ECgene: NDRG3 H-InvDB: NDRG3

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for NDRG3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NDRG3 gene:
    Search GeneIP for patents involving NDRG3

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