Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

NDRG3 Gene

protein-coding GIFtS: 49
GCID: GC20M035280

NDRG family member 3

Explore 9 diseases affiliated with
NDRG3 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
NDRG Family Member 3¹ ²
N-Myc Downstream-Regulated Gene 3 Protein² ³
Protein NDRG3²

External Ids:	HGNC: 14462¹	Entrez Gene: 57446²	Ensembl: ENSG00000101079⁷	OMIM: 605273⁵	UniProtKB: Q9UGV2³

ORGUL members:
	NONCODE:n410908

Export aliases for NDRG3 gene to outside databases

Previous GC identifers: GC20M035008 GC20M035918 GC20M035965 GC20M034713 GC20M032016

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000020.10 NC_018931.1 NT_011362.10

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the NDRG3 gene promoter:
MEF-2 Pax-6 HNF-3beta LCR-F1 C/EBPalpha E47 MEF-2A Hand1 ARP-1 aMEF-2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: NDRG3 promoter sequence

Search SABiosciences Chromatin IP Primers for NDRG3

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NDRG3

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q11.21-q11.23 Ensembl cytogenetic band: 20q11.23 HGNC cytogenetic band: 20q11.21-q11.23

NDRG3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NDRG3 gene location

GeneLoc information about chromosome 20 GeneLoc Exon Structure

GeneLoc location for GC20M035280: view genomic region (about GC identifiers)

Start:	35,280,169 bp from pter	End:	35,374,481 bp from pter
Size:	94,313 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: NDRG3_HUMAN, Q9UGV2 (See protein sequence)

Recommended Name: Protein NDRG3

Size: 375 amino acids; 41409 Da

Secondary accessions: A2A2S8 E1P5U7 E1P5U8 Q5TH32 Q96PL8 Q96SM2 Q9BXY7 Q9H3N7 Q9H411 Q9H8J6

Alternative splicing: 3 isoforms: Q9UGV2-1 Q9UGV2-2 Q9UGV2-3

Explore the universe of human proteins at neXtProt for NDRG3: NX_Q9UGV2

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9UGV2

NDRG3 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_071922.2 NP_114402.1

ENSEMBL proteins:

ENSP00000345292 ENSP00000362909 ENSP00000352703 ENSP00000416636 ENSP00000442813

ENSP00000362878

Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene Protein Over-expression Lysate: NDRG3 OriGene Custom Protein Services for NDRG3
	GenScript Custom Purified and Recombinant Proteins Services for NDRG3
	Novus Biologicals NDRG3 Protein
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for NDRG3

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IDA	11936845

NDRG3 for ontologies About GeneDecksing

NDRG3 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Cell Signaling Technology (CST) Antibodies for NDRG3
	OriGene Antibodies (see all 2): NDRG3 OriGene Custom Antibody Services for NDRG3
	GenScript Custom Superior Antibodies Services for NDRG3
	Novus Biologicals NDRG3 Antibodies
	Abcam antibodies for NDRG3
	Uscn Antibodies for NDRG3
	Search ThermoFisher Antibodies for NDRG3

Assay Products for NDRG3:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for NDRG3
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for NDRG3

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

NDRG3 for domains About GeneDecksing

1 InterPro domain/family:

IPR004142 Ndr

Graphical View of Domain Structure for InterPro Entry Q9UGV2

ProtoNet protein and cluster: Q9UGV2

1 Blocks protein family: IPB004142 Ndr family

UniProtKB/Swiss-Prot: NDRG3_HUMAN, Q9UGV2

Similarity: Belongs to the NDRG family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

miRNA Products:		OriGene 3'-UTR Clone (see all 2): NDRG3 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NDRG3
		8/42 QIAGEN miScript miRNA Assays for microRNAs that regulate NDRG3 (see all 42):
		hsa-miR-194* hsa-miR-21* hsa-miR-4291 hsa-miR-140-5p hsa-miR-3607-3p hsa-miR-765 hsa-miR-759 hsa-miR-298

		SwitchGear 3'UTR luciferase reporter plasmid: NDRG3 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NDRG3 (see all 7) OriGene shRNA RFP: NDRG3 OriGene siRNA: NDRG3
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NDRG3

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for NDRG3

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NDRG3 (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NDRG3 (see all 3) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): NDRG3 (NM_022477)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for NDRG3
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NDRG3

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for NDRG3
		Search LifeMap BioReagents cell lines for NDRG3

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NDRG3

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003674	molecular_function	ND	--

NDRG3 for ontologies About GeneDecksing

Animal Models:
1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Ndrg3):

mortality/aging

NDRG3 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Apoptosis and Autophagy

Apoptosis and Autophagy

1.00

Angiogenesis

Angiogenesis

1.00

PI3K / Akt Signaling

PI3K / Akt Signaling

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

3 Cell Signaling Technology (CST) Pathways for NDRG3

	Apoptosis and Autophagy
	Angiogenesis
	PI3K / Akt Signaling

NDRG3 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for NDRG3

STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

5/7 Interacting proteins for NDRG3 (Q9UGV2³ ENSP00000345292⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 7)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
DNAJB4	Q9UDY4³	I2D: score=1
GLRA3	O75311³	I2D: score=1
MTHFSD	Q2M296³	I2D: score=1
PPIF	P30405³	I2D: score=1
SPEN	Q96T58³	I2D: score=1

About this table

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007283	spermatogenesis	NAS	11406283
GO:0030154	cell differentiation	NAS	11406283
GO:0030308	negative regulation of cell growth	NAS	11406283

NDRG3 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for NDRG3
Search CenterWatch for drugs/clinical trials and news about NDRG3

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for NDRG3 gene (2 alternative transcripts):

NM_022477.3 NM_032013.3

Unigene Cluster for NDRG3:

NDRG family member 3

Hs.437338 [show with all ESTs]

Unigene Representative Sequence: AK128068

7 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000349004(uc002xfw.3 uc002xfx.3 uc010zvq.2 uc010zvr.2)

ENST00000373803 ENST00000359675 ENST00000480314 ENST00000422536 ENST00000540765

ENST00000373773

miRNA Products:		OriGene 3'-UTR Clone (see all 2): NDRG3 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NDRG3
		8/42 QIAGEN miScript miRNA Assays for microRNAs that regulate NDRG3 (see all 42):
		hsa-miR-194* hsa-miR-21* hsa-miR-4291 hsa-miR-140-5p hsa-miR-3607-3p hsa-miR-765 hsa-miR-759 hsa-miR-298

		SwitchGear 3'UTR luciferase reporter plasmid: NDRG3 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NDRG3 (see all 7) OriGene shRNA RFP: NDRG3 OriGene siRNA: NDRG3
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NDRG3

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NDRG3 (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NDRG3 (see all 3) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): NDRG3 (NM_022477)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for NDRG3
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NDRG3

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NDRG3 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat NDRG3
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NDRG3
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NDRG3

Additional cDNA sequence:

AB044943.1 AF308609.1 AK023618.1 AK027665.1 AK128068.1 AK295420.1 AK295466.1 BC136489.1

BC144169.1 NR_038370.1

10 DOTS entries:

DT.95086156 DT.92475313 DT.101980321 DT.92475441 DT.100647967 DT.100794465 DT.100794474 DT.97847328

DT.120833203 DT.97847330

24/197 AceView cDNA sequences (see all 197):

NM_022477 AI659189 AA311302 AI027140 CA418050 BM981949 BQ009388 AA322907

BE328324 CA437797 T33083 AI435981 F09769 BU177085 AA322542 T33098

AK128068 AU132685 BQ640166 T33084 AF308609 F12132 BM663661 CA420077

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

NDRG3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCTACTGTTA

About this image
See NDRG3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NDRG3

SOURCE GeneReport for Unigene cluster: Hs.437338

UniProtKB/Swiss-Prot: NDRG3_HUMAN, Q9UGV2

Tissue specificity: Ubiquitous. Highly expressed in brain

SABiosciences Expression via Pathway-Focused PCR Array including NDRG3:

Prostate Cancer in human mouse rat

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NDRG3 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat NDRG3
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NDRG3
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NDRG3

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NDRG3

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for NDRG3 gene from 8/24 species (see all 24) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	NDRG3⁶	Uncharacterized protein	83(a)	1 ↔ 1	20(830522-861179)
lizard (Anolis carolinensis)	Reptilia	NDRG3⁶	--	82(a)	1 ↔ 1	4(134696351-134730964)
African clawed frog (Xenopus laevis)	Amphibia	Xl.17664²	Xenopus laevis transcribed sequence with moderate similarity more	76.82(n)		CA794198.1
zebrafish (Danio rerio)	Actinopterygii	BC044139.1²	--	75.57(n)		327395 BC044139.1
fruit fly (Drosophila melanogaster)	Insecta	MESK2¹	Misexpression suppressor of KSR 2	51.17(n) 43.16(a)		37451 NM_206191.1 NP_995913.1
worm (Caenorhabditis elegans)	Secernentea	Y48G10A.3¹	Protein Y48G10A.3	47.59(n) 34.54(a)		173217 NM_060968.3 NP_493369.1
thale cress (Arabidopsis thaliana)	eudicotyledons	NDL3⁶ NDL1⁶ (see all 3)	N-MYC downregulated-like 1 protein (see all 3)	26(a) 26(a) (see all 3)	many ↔ many many ↔ many (see all 3)	2(8485991-8488720) 5(22957877-22960916)
rice (Oryza sativa)	Liliopsida	-- -- (see all 4)	pollen-specific protein SF21, putative, expressed (see all 4)	26(a) 26(a) (see all 4)	many ↔ many many ↔ many (see all 4)	2(7006064-7010651) 6(21636462-21640998)

ENSEMBL Gene Tree for NDRG3 (if available)
TreeFam Gene Tree for NDRG3 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for NDRG3 gene

NDRG2² NDRG4² NDRG1²

4 SIMAP similar genes for NDRG3 using alignment to 6 protein entries: NDRG3_HUMAN (see all proteins):

NDRG1 TRG14 NDRG4 NDRG2

NDRG3 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 20 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs139057651^1,2		--	35279703(+)	`GCACTC/TGGTCT`	3	--	int¹		0	--	--	--	--
rs141570335^1,2		--	35279726(+)	`GATGGA/GTACAA`	3	--	int¹		0	--	--	--	--
rs6028573^1,2	C,H	--	35279827(+)	`ACACAG/AGTGGT`	3	--	int¹		4		NS EA	398
rs187543181^1,2		--	35279844(+)	`GTGACA/GTGGAC`	3	--	int¹		0	--	--	--	--
rs115471260^1,2		--	35279856(+)	`ACCTTC/ATCAAG`	3	--	int¹		1		WA	118
rs6101640^1,2	F,H,	--	35279894(+)	`ACAACA/GCTGTC`	3	--	int¹		4		NS EA	416
rs147031443^1,2		--	35280079(+)	`AATCAC/TATGTG`	3	--	int¹		0	--	--	--	--
rs117010729^1,2	F,	--	35280118(+)	`CAACTC/TGGTCC`	3	--	int¹		1		NA	120
rs79019885^1,2	C,F,	--	35280156(+)	`NNNNAA/GTAACA`	3	--	int¹		1		NA	120
rs148124171^1,2		--	35280226(+)	`TACTCC/TGGCAG`	3	--	ut3¹ nc-transcript-variant		0	--	--	--	--

HapMap Linkage Disequilibrium report for NDRG3 (35280169 - 35374481 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for NDRG3: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NDRG3

DNA2.0 Custom Variant and Variant Library Synthesis for NDRG3

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

NDRG3 for disorders           About GeneDecksing

OMIM gene information: 605273    OMIM disorders: --

9 diseases for NDRG3:    About MalaCards

motor peripheral neuropathy peripheral neuropathy hepatitis b neuropathy

hepatocellular carcinoma hepatitis prostate cancer carcinoma

prostatitis

1 disease from the University of Copenhagen DISEASES database for NDRG3:

Motor peripheral neuropathy

Export disorders for NDRG3 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for NDRG3 gene, integrated from 9 sources (see all 22):
(articles sorted by number of sources associating them with NDRG3)

Utopia: connect your pdf to the dynamic
world of online information

Characterization and expression of three novel differentiation- related genes belong to the human NDRG gene family. (PubMed id 11936845)^{1, 2, 9} Qu X.... He F. (2002)
Characterization of the human NDRG gene family: a newly identified member, NDRG4, is specifically expressed in brain and heart. (PubMed id 11352569)^{1, 2, 9} Zhou R.-H.... Miyata T. (2001)
Differential expression patterns of NDRG family prote ins in the central nervous system. (PubMed id 17998568)^{1, 3} Okuda T....Miyata T. (2008)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)^{1, 2} Deloukas P....Rogers J. (2001)
N-myc downstream-regulated gene 1 is mutated in hereditary motor and sensory neuropathy-Lom. (PubMed id 10831399)^{1, 3} Kalaydjieva L.... Thomas P.K. (2000)
Cloning and expression pattern of the human NDRG3 gene. (PubMed id 11406283)^{1, 9} Zhao W....Mao Y. (2001)
A census of human soluble protein complexes. (PubMed id 22939629)¹ Havugimana P.C....Emili A. (2012)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)
miR-122 inhibits viral replication and cell proliferat ion in hepatitis B virus-related hepatocellular carcinoma and targets NDRG3. (PubMed id 21725618)¹ Fan C.G....Liu Y.G. (2011)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 57446	HGNC: 14462	AceView: NDRG3	Ensembl:ENSG00000101079	euGenes: HUgn57446
ECgene: NDRG3	H-InvDB: NDRG3

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for NDRG3	Pharmacogenomics, SNPs, Pathways

Intellectual Property for NDRG3 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for NDRG3 gene:
Search GeneIP for patents involving NDRG3

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	OriGene Antibodies for NDRG3		OriGene shRNA RFP for NDRG3
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NDRG3		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NDRG3
	OriGene Protein Over-expression Lysate for NDRG3		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for NDRG3		OriGene 3'-UTR Clone for NDRG3
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NDRG3		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NDRG3
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for NDRG3		OriGene Custom Protein Services for NDRG3
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NDRG3
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NDRG3
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NDRG3
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NDRG3
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NDRG3
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NDRG3

	GenScript Custom Purified and Recombinant Proteins Services for NDRG3		GenScript cDNA clones with any tag delivered in your preferred vector for NDRG3
	GenScript Custom Assay Services for NDRG3		GenScript Custom Superior Antibodies Services for NDRG3
	GenScript Custom overexpressing Cell Line Services for NDRG3		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Antibodies & Assays for NDRG3

	Regulatory tfbs in NDRG3 promoter
	Search Chromatin IP Primers for NDRG3
	RT² qPCR Primer Assay in human, mouse, rat NDRG3
	Search GNC Networks for NDRG3
	SABiosciences PCR Arrays including human, mouse, rat NDRG3

Search Tocris compounds for NDRG3

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	NDRG3 antibodies
	NDRG3 proteins

	Antibodies for NDRG3
	See all of Abcam's Antibodies, Kits and Proteins for NDRG3
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

NDRG3 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for NDRG3

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NDRG3

	SwitchGear 3'UTR luciferase reporter plasmids for NDRG3
	SwitchGear Promoter luciferase reporter plasmids for NDRG3

Search ThermoFisher Antibodies for NDRG3

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NDRG3

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes NDRG3 gene at Home site.

hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4

Advanced Search

Export list of displayed genes

NDRG3 Gene

NDRG family member 3

Aliases
for NDRG3 gene

Summaries
for NDRG3 gene

Genomic Views
for NDRG3 gene

Proteins
for NDRG3 gene

Protein Domains /
Families
for NDRG3 gene

Function
for NDRG3 gene

Pathways & Interactions
for NDRG3 gene

Drugs & Compounds
for NDRG3 gene

Transcripts
for NDRG3 gene

Expression
for NDRG3 gene

Orthologs
for NDRG3 gene

Paralogs
for NDRG3 gene

Genomic Variants
for NDRG3 gene

Disorders / Diseases
for NDRG3 gene

Publications
for NDRG3 gene

External Searches for NDRG3 gene

Genome Databases showing NDRG3 gene

Other Databases showing NDRG3 gene

Specialized Databases showing NDRG3 gene

Intellectual Property
for NDRG3 gene

Products
for NDRG3 gene

View Random Gene

Advanced Search

Export list of displayed genes

NDRG3 Gene

NDRG family member 3

Aliasesfor NDRG3 gene

Summariesfor NDRG3 gene

Genomic Viewsfor NDRG3 gene

Proteinsfor NDRG3 gene

Protein Domains /Familiesfor NDRG3 gene

Functionfor NDRG3 gene

Pathways & Interactionsfor NDRG3 gene

Drugs & Compoundsfor NDRG3 gene

Transcriptsfor NDRG3 gene

Expression for NDRG3 gene

Orthologsfor NDRG3 gene

Paralogsfor NDRG3 gene

Genomic Variantsfor NDRG3 gene

Disorders / Diseasesfor NDRG3 gene

Publicationsfor NDRG3 gene

External Searches for NDRG3 gene

Genome Databases showing NDRG3 gene

Other Databases showing NDRG3 gene

Specialized Databases showing NDRG3 gene

Intellectual Propertyfor NDRG3 gene

Productsfor NDRG3 gene

View Random Gene

Aliases
for NDRG3 gene

Summaries
for NDRG3 gene

Genomic Views
for NDRG3 gene

Proteins
for NDRG3 gene

Protein Domains /
Families
for NDRG3 gene

Function
for NDRG3 gene

Pathways & Interactions
for NDRG3 gene

Drugs & Compounds
for NDRG3 gene

Transcripts
for NDRG3 gene

Expression
for NDRG3 gene

Orthologs
for NDRG3 gene

Paralogs
for NDRG3 gene

Genomic Variants
for NDRG3 gene

Disorders / Diseases
for NDRG3 gene

Publications
for NDRG3 gene

Intellectual Property
for NDRG3 gene

Products
for NDRG3 gene