Aliases for NDOR1 Gene
External Ids for NDOR1 Gene
Previous GeneCards Identifiers for NDOR1 Gene
This gene encodes an NADPH-dependent diflavin reductase that contains both flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) binding domains. The encoded protein catalyzes the transfer of electrons from NADPH through FAD and FMN cofactors to potential redox partners. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]
GeneCards Summary for NDOR1 Gene
NDOR1 (NADPH Dependent Diflavin Oxidoreductase 1) is a Protein Coding gene. Diseases associated with NDOR1 include colorectal adenocarcinoma. Among its related pathways are Metabolism and Cytosolic Iron-sulfur Cluster Assembly. GO annotations related to this gene include iron ion binding and flavin adenine dinucleotide binding.
UniProtKB/Swiss-Prot for NDOR1 Gene
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins (By similarity). Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe/S cluster of CIAPIN1.