Aliases for NDFIP2 Gene
External Ids for NDFIP2 Gene
Previous GeneCards Identifiers for NDFIP2 Gene
GeneCards Summary for NDFIP2 Gene
NDFIP2 (Nedd4 Family Interacting Protein 2) is a Protein Coding gene. GO annotations related to this gene include signal transducer activity and WW domain binding. An important paralog of this gene is NDFIP1.
UniProtKB/Swiss-Prot for NDFIP2 Gene
Activates HECT domain-containing E3 ubiquitin-protein ligases, including ITCH, NEDD4, NEDD4L, SMURF2, WWP1 and WWP2, and consequently modulates the stability of their targets. As a result, may control many cellular processes. Recruits ITCH, NEDD4 and SMURF2 to endosomal membranes. May modulate EGFR signaling.