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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NDFIP2 Gene

protein-coding   GIFtS: 51
GCID: GC13P080055

Nedd4 family interacting protein 2
 Explore 5 diseases affiliated with
NDFIP2 via
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 Human Malady Compendium 
Biological research products
for NDFIP2    

Aliases
for NDFIP2 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Nedd4 Family Interacting Protein 21 2     NEDD4 WW Domain-Binding Protein 5A2 3
KIAA11651 3 5     N4wbp5a1
N4WBP5A2 3 5     MAPK-Activating Protein PM04 PM05 PM06 PM072
Putative MAPK-Activating Protein PM04/PM05/PM06/PM072 3     NEDD4 Family-Interacting Protein 22
Putative NF-Kappa-B-Activating Protein 4132 3     NF-Kappa-B-Activating Protein 4132

External Ids:    HGNC: 185371   Entrez Gene: 546022   Ensembl: ENSG000001024717   OMIM: 6100415   UniProtKB: Q9NV923   

Export aliases for NDFIP2 gene to outside databases

Previous GC identifers: GC13P074050 GC13P078992 GC13P077853 GC13P078878 GC13P060758


Summaries
for NDFIP2 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: NFIP2_HUMAN, Q9NV92
Function: Activates HECT domain-containing E3 ubiquitin-protein ligases, including ITCH, NEDD4, NEDD4L, SMURF2, WWP1
and WWP2, and consequently modulates the stability of their targets. As a result, may control many cellular processes.
Recruits ITCH, NEDD4 and SMURF2 to endosomal membranes. May modulate EGFR signaling

Gene Wiki entry for NDFIP2


Genomic Views
for NDFIP2 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000013.10  NC_018924.1  NT_024524.14  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NDFIP2 gene promoter:
         AhR   C/EBPbeta   AP-1   CUTL1   c-Ets-1   Arnt   RORalpha1   NRF-2   SEF-1 (1)   RSRFC4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: NDFIP2 promoter sequence
   Search SABiosciences Chromatin IP Primers for NDFIP2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NDFIP2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q31.1   Ensembl cytogenetic band:  13q31.1   HGNC cytogenetic band: 13q22.1

NDFIP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NDFIP2 gene location

GeneLoc information about chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13P080055:  view genomic region     (about GC identifiers)

Start:
 80,055,259 bp from pter      End:
 80,130,212 bp from pter
Size:
 74,954 bases      Orientation:
 plus strand

Proteins
for NDFIP2 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: NFIP2_HUMAN, Q9NV92 (See protein sequence)
Recommended Name: NEDD4 family-interacting protein 2  
Size: 336 amino acids; 36390 Da
Subunit: Forms heterodimers with NDFIP1. Interacts with HECT domain-containing E3 ubiquitin-protein ligases, including
NEDD4. Interacts with NEDD4L (By similarity). Interacts with PTEN. When phosphorylated at Tyr-167, interacts with SRC
and LYN SH2 domain. May thus act as a scaffold that recruits SRC to NDFIP1, enhancing NDFIP1 phosphorylation.
Interacts with SLC11A2/DMT1. May interact with phosphorylated EGFR
Subcellular location: Endosome membrane; Multi-pass membrane protein. Golgi apparatus membrane. Endosome,
multivesicular body membrane
Sequence caution: Sequence=AAH21988.1; Type=Erroneous initiation; Sequence=AAH26126.1; Type=Erroneous initiation;
Sequence=BAA91863.1; Type=Erroneous initiation;
Secondary accessions: Q7Z2H3 Q7Z428 Q8TAR3 Q9ULQ5

Explore the universe of human proteins at neXtProt for NDFIP2: NX_Q9NV92

Post-translational modifications:

  • Ubiquitinated by NEDD4 and ITCH. Also ubiquitinated by NEDD4L. Ubiquitination by NEDD4 or NEDD4L does not affect
    • turnover (By similarity)1
  • Undergoes transient tyrosine-phosphorylation following EGF stimulation, most probably catalyzed by SRC. Also
    • phosphorylated by LYN and FYN1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9NV92

    • NDFIP2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001154879.1  NP_061953.2  

    ENSEMBL proteins: 
     ENSP00000218652   ENSP00000419200   ENSP00000419776  

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    Novus Biologicals NDFIP2 Lysates
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    Uscn Proteins for NDFIP2

    Gene Ontology (GO): 5/8 cellular component terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0005737cytoplasm IDA12796489
    GO:0005739mitochondrion IDA12796489
    GO:0005783endoplasmic reticulum IDA12796489
    GO:0005794Golgi apparatus IDA12796489


    NDFIP2 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for NDFIP2 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    NDFIP2 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR019325 NEDD4/BSD2

    Graphical View of Domain Structure for InterPro Entry Q9NV92

    ProtoNet protein and cluster: Q9NV92

    UniProtKB/Swiss-Prot: NFIP2_HUMAN, Q9NV92
    Domain: The PY (WW-binding) motifs are required for E3 ubiquitin-protein ligase activation and for ubiquitination


    Function
    for NDFIP2 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: NFIP2_HUMAN, Q9NV92
    Function: Activates HECT domain-containing E3 ubiquitin-protein ligases, including ITCH, NEDD4, NEDD4L, SMURF2, WWP1
    and WWP2, and consequently modulates the stability of their targets. As a result, may control many cellular processes.
    Recruits ITCH, NEDD4 and SMURF2 to endosomal membranes. May modulate EGFR signaling
    Induction: By T-cell activation

    miRNA
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    hsa-miR-142-5p hsa-miR-579 hsa-miR-513a-5p hsa-miR-200a hsa-miR-134 hsa-miR-374c hsa-miR-141 hsa-miR-1244
    SwitchGear 3'UTR luciferase reporter plasmid: NDFIP2 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004871signal transducer activity IMP12761501
    GO:0005515protein binding IPI18776082
    GO:0050699WW domain binding IPI12796489


    NDFIP2 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for NDFIP2:
     Upregulation of NF-kappaB path 


    Pathways & Interactions
    for NDFIP2 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for NDFIP2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

    5/15 Interacting proteins for NDFIP2 (Q9NV923 ENSP000002186524) via UniProtKB, MINT, STRING, and/or I2D (see all 15)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    WWP2O003083, ENSP000003482834I2D: score=2 STRING: ENSP00000348283
    FYNP062413, ENSP000003576564I2D: score=1 STRING: ENSP00000357656
    ITCHQ96J023, ENSP000003639984I2D: score=1 STRING: ENSP00000363998
    PTENP604843, ENSP000003610214I2D: score=1 STRING: ENSP00000361021
    SMURF1Q9HCE73, ENSP000003546214I2D: score=1 STRING: ENSP00000354621
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007165signal transduction IMP12761501
    GO:0010629negative regulation of gene expression IMP18776082
    GO:0031398positive regulation of protein ubiquitination IMP18776082
    GO:0032410negative regulation of transporter activity IMP18776082
    GO:0043123positive regulation of I-kappaB kinase/NF-kappaB cascade IMP12761501


    NDFIP2 for ontologies           About GeneDecksing



    Drugs & Compounds
    for NDFIP2 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NDFIP2
    Search CenterWatch for drugs/clinical trials and news about NDFIP2 / NFIP2 

    Transcripts
    for NDFIP2 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for NDFIP2 gene (2 alternative transcripts): 
    NM_001161407.1  NM_019080.2  

    Unigene Cluster for NDFIP2:

    Nedd4 family interacting protein 2
    Hs.525093  [show with all ESTs]
    Unigene Representative Sequence: NM_019080
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000218652(uc010tib.2 uc001vlf.3 uc001vlg.3) ENST00000487865
    ENST00000465762 ENST00000494647

    miRNA
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    8/59 QIAGEN miScript miRNA Assays for microRNAs that regulate NDFIP2 (see all 59):
    hsa-miR-142-5p hsa-miR-579 hsa-miR-513a-5p hsa-miR-200a hsa-miR-134 hsa-miR-374c hsa-miR-141 hsa-miR-1244
    SwitchGear 3'UTR luciferase reporter plasmid: NDFIP2 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NDFIP2 (see all 7)
    OriGene shRNA RFP: NDFIP2
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    Clone
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    Additional cDNA sequence: 

    AB032991.1 AB097019.1 AB097028.1 AB097029.1 AB097030.1 AB097031.1 AK001723.1 AK098708.1 
    AK294839.1 AK297197.1 BC021988.1 BC026126.2 

    5 DOTS entries:

    DT.454612  DT.95116329  DT.100708610  DT.120778350  DT.86839933 

    24/242 AceView cDNA sequences (see all 242):

    BQ438996 BQ878884 AI742122 AA490415 AU117365 R38706 BE395930 BX382047 
    BU157279 BE018403 AW131246 AI092216 BQ228707 AI655642 AU133224 BM976935 
    BQ896929 AW571569 AA508087 AI571449 BM989394 BM978812 BC021988 AW300534 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for NDFIP2    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b
    SP1:                    -     -     -                                                         
    SP2:                                -                       -     -                           
    SP3:                    -     -     -                       -                                 
    SP4:                          -                                                               
    SP5:                    -     -     -                                                         


    ECgene alternative splicing isoforms for NDFIP2

    Expression
    for NDFIP2 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NDFIP2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CATAACTTAC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    NDFIP2 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    EyeRetinaEye
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See NDFIP2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NDFIP2

    SOURCE GeneReport for Unigene cluster: Hs.525093

    UniProtKB/Swiss-Prot: NFIP2_HUMAN, Q9NV92
    Tissue specificity: Expressed in brain, lung, heart, skeletal muscle, kidney, liver and placenta

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    In Situ
    Assay Products:     
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    Orthologs
    for NDFIP2 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for NDFIP2 gene from 5/19 species (see all 19)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves NDFIP21 Nedd4 family interacting protein 2 81.12(n)
    84.98(a)    		   418803  NM_001030820.1  NP_001025991.1 
    lizard
    (Anolis carolinensis)    		 Reptilia NDFIP26
    		 --
    		 77(a)
    		 1 ↔ 1
    		 3(96964667-96996453)
    African clawed frog
    (Xenopus laevis)    		 Amphibia MGC687082 hypothetical protein MGC68708 81.82(n)    BC060023.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii wufa92h032 Danio rerio cDNA clone MGC63948 IMAGE6791361, complete more 80.79(n)    BC059183.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta Ndfip6
    		 Nedd4 family interacting protein
    		 26(a)
    		 1 → many
    		 3L(17640542-17647380)


    ENSEMBL Gene Tree for NDFIP2 (if available)
    TreeFam Gene Tree for NDFIP2 (if available) 

    Paralogs
    for NDFIP2 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NDFIP2 gene
    NDFIP12  
    1 SIMAP similar gene for NDFIP2 using alignment to 3 protein entries:     NFIP2_HUMAN (see all proteins):
    NDFIP1

    NDFIP2 for paralogs           About GeneDecksing



    Genomic Variants
    for NDFIP2 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1190 NCBI SNPs in NDFIP2 are shown (see all 1190)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 13 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs790542191,2
    		F,--80053299(+) AAATAC/AGCTTT 3 -- us2k1 int11Minor allele frequency- A:0.04WA 118
    rs1815239651,2
    		--80053300(+) AATACA/GCTTTC 3 -- int1 us2k10--------
    rs1436866961,2
    		--80053456(+) CTGCAC/TTGGGT 3 -- us2k1 int10--------
    rs767003881,2
    		C--80053577(+) TAGATA/CGTAAG 3 -- int1 us2k10--------
    rs1480344981,2
    		--80053708(+) GCATAC/TGTTTA 3 -- us2k1 int10--------
    rs1417196871,2
    		--80053731(+) CTAAAA/CTACAT 3 -- us2k1 int10--------
    rs735515221,2
    		C,--80053805(+) AGCACA/GGTAAT 3 -- int1 us2k12Minor allele frequency- G:0.10WA 120
    rs1137223921,2
    		C,--80053812(+) TAATGC/TTTTAT 3 -- int1 us2k12Minor allele frequency- T:0.02NA 122
    rs1863048741,2
    		--80053919(+) TCAAAA/GAGTTT 3 -- us2k1 int10--------
    rs412882681,2
    		C,F,--80054098(+) TGTTAT/CGTTAA 3 -- us2k1 int14Minor allele frequency- C:0.17WA CSA NA 242

    HapMap Linkage Disequilibrium report for NDFIP2 (80055259 - 80130212 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 8 variations for NDFIP2
         3 CNVs: 101788 4812 58643
         5 Indels: 45201 39989 42965 25305 61338

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    Disorders / Diseases
    for NDFIP2 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    NDFIP2 for disorders           About GeneDecksing

    OMIM gene information: 610041    OMIM disorders: --

    5 diseases for NDFIP2:    About MalaCards
    hypochromic anemia    anemia    pancreatic cancer    pancreatitis
    hypertension

    1 disease from the University of Copenhagen DISEASES database for NDFIP2:
    Hypochromic anemia

    Export disorders for NDFIP2 gene to outside databases

    Publications
    for NDFIP2 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NDFIP2 gene, integrated from 9 sources (see all 23):
    (articles sorted by number of sources associating them with NDFIP2)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. (PubMed id 10574461)1, 2, 3 Hirosawa M.... Ohara O. (1999)
    2. Control of the activity of WW-HECT domain E3 ubiquitin ligases by NDFIP proteins. (PubMed id 19343052)1, 2, 9 Mund T. and Pelham H.R. (2009)
    3. Regulation of PTEN/Akt and MAP kinase signaling pathways by the ubiquitin ligase activators Ndfip1 and Ndfip2. (PubMed id 20534535)1, 2 Mund T. and Pelham H.R. (2010)
    4. Regulation of the divalent metal ion transporter DMT1 and iron homeostasis by a ubiquitin-dependent mechanism involving Ndfips and WWP2. (PubMed id 18776082)1, 2 Foot N.J....Kumar S. (2008)
    5. The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)1, 2 Dunham A.... Ross M.T. (2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    8. Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways. (PubMed id 12761501)1, 2 Matsuda A....Sugano S. (2003)
    9. Cloning and characterization of N4WBP5A, an inducible, cyclosporine- sensitive, Nedd4-binding protein in human T lymphocytes. (PubMed id 12796489)1, 2 Cristillo A.D.... Bierer B.E. (2003)
    10. Regulation of the epithelial sodium channel by N4WBP5A, a novel Nedd4/Nedd4-2-interacting protein. (PubMed id 12050153)1, 3 Konstas A.A....Kumar S. (2002)

    External Searches for NDFIP2 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
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    Genome Databases showing NDFIP2 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 54602 HGNC: 18537 AceView: NDFIP2.1 Ensembl:ENSG00000102471 euGenes: HUgn54602
    ECgene: NDFIP2 H-InvDB: NDFIP2

    Other Databases showing NDFIP2 gene

    (According to HUGE)
    About This Section
    HUGE: KIAA1165

    Specialized Databases showing NDFIP2 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NDFIP2 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for NDFIP2 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for NDFIP2 gene:
    Search GeneIP for patents involving NDFIP2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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