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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NDFIP1 Gene

protein-coding   GIFtS: 47
GCID: GC05P141468

Nedd4 family interacting protein 1

 Explore 8 diseases affiliated with
NDFIP1 via our new
 Human Malady Compendium 
Biological research products
for NDFIP1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Nedd4 Family Interacting Protein 11 2     Putative NF-Kappa-B-Activating Protein 1642 3
N4WBP51 2 3 5     Putative NFKB And MAPK-Activating Protein2 3
Breast Cancer-Associated Protein SGA-1M2 3     MGC109241
NEDD4 WW Domain-Binding Protein 52 3     NEDD4 Family-Interacting Protein 12
Putative MAPK-Activating Protein PM132 3     

External Ids:    HGNC: 175921   Entrez Gene: 807622   Ensembl: ENSG000001315077   OMIM: 6120505   UniProtKB: Q9BT673   

Export aliases for NDFIP1 gene to outside databases

Previous GC identifers: GC05P142071 GC05P141471 GC05P141516 GC05P136635


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NDFIP1:
The protein encoded by this gene belongs to a small group of evolutionarily conserved proteins with three transmembrane
domains. It is a potential target for ubiquitination by the Nedd4 family of proteins. This protein is thought to be
part of a family of integral Golgi membrane proteins. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: NFIP1_HUMAN, Q9BT67
Function: Activates HECT domain-containing E3 ubiquitin-protein ligases, including NEDD4 and ITCH, and consequently
modulates the stability of their targets. As a result, controls many cellular processes. Prevents chronic T-helper
cells-mediated inflammation by activating ITCH and thus controlling JUNB degradation (By similarity). In cortical
neurons, mediates the ubiquitination of SLC11A2/DMT1 by NEDD4L, leading to down-regulation of the divalent metal
transporter and protection of the cells from cobalt and iron toxicity. Modulates EGFR signaling through multiple
pathways. In particular, may regulate the ratio of AKT1-to-MAPK8 signaling in response to EGF, acting on AKT1 probably
through PTEN destabilization and on MAPK8 through ITCH-dependent MAP2K4 inactivation. As a result, may control cell
growth rate




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NC_018916.1  NT_029289.11  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NDFIP1 gene promoter:
         E2F-3a   E2F-4   ISGF-3   E2F-5   Pbx1a   Pax-5   E2F-2   E2F-1   E2F   deltaCREB   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNDFIP1 promoter sequence
   Search SABiosciences Chromatin IP Primers for NDFIP1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NDFIP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q31.3   Ensembl cytogenetic band:  5q31.3   HGNC cytogenetic band: 5q31.3

NDFIP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NDFIP1 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05P141468:  view genomic region     (about GC identifiers)

Start:
141,488,070 bp from pter      End:
141,534,008 bp from pter
Size:
45,939 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: NFIP1_HUMAN, Q9BT67 (See protein sequence)
Recommended Name: NEDD4 family-interacting protein 1  
Size: 221 amino acids; 24899 Da
Subunit: Forms heterodimers with NDFIP2. Interacts with several E3 ubiquitin-protein ligases, including NEDD4, NEDD4L
and WWP2. Interacts with ITCH, U2SURP and WWP2 (By similarity). The interaction with NEDD4, NEDD4L and ITCH leads to
relocalization of these proteins to exosomes and eventually to exosomal secretion. Interacts with SLC11A2/DMT1.
Interacts with PTEN. May interact with phosphorylated EGFR
Subcellular location: Endosome membrane; Multi-pass membrane protein. Golgi apparatus membrane (By similarity).
Secreted. Note=Detected in exosomes and secreted via the exosomal pathway
Secondary accessions: B2RDB8 D3DQF0 Q658T8 Q8N2E3 Q8N2F9
Alternative splicing: 2 isoforms:  Q9BT67-1   Q9BT67-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NDFIP1: NX_Q9BT67

Post-translational modifications:

  • Ubiquitinated by NEDD4 and ITCH; mono-, di- and polyubiquitinated forms are detected. Ubiquitination regulates its
  • degradation1
  • Undergoes transient tyrosine phosphorylation following EGF stimulation, most probably by catalyzed by SRC.
  • Phosphorylation SRC is enhanced in the presence of NDFIP2 which may act as a scaffold to recruit SRC to NDFIP11
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9BT67

  • NDFIP1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_085048.1  
    ENSEMBL proteins: 
     ENSP00000253814  

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    Uscn Proteins for NDFIP1

    Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0005576extracellular region IEA--
    GO:0005794Golgi apparatus ----
    GO:0005938cell cortex IEA--
    GO:0010008endosome membrane IEA--


    NDFIP1 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    NDFIP1 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR019325 NEDD4/BSD2

    Graphical View of Domain Structure for InterPro Entry Q9BT67

    ProtoNet protein and cluster: Q9BT67

    UniProtKB/Swiss-Prot: NFIP1_HUMAN, Q9BT67
    Domain: The PY (WW-binding) motifs are required for E3 ubiquitin-protein ligase binding and activation and for
    ubiquitination


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: NFIP1_HUMAN, Q9BT67
    Function: Activates HECT domain-containing E3 ubiquitin-protein ligases, including NEDD4 and ITCH, and consequently
    modulates the stability of their targets. As a result, controls many cellular processes. Prevents chronic T-helper
    cells-mediated inflammation by activating ITCH and thus controlling JUNB degradation (By similarity). In cortical
    neurons, mediates the ubiquitination of SLC11A2/DMT1 by NEDD4L, leading to down-regulation of the divalent metal
    transporter and protection of the cells from cobalt and iron toxicity. Modulates EGFR signaling through multiple
    pathways. In particular, may regulate the ratio of AKT1-to-MAPK8 signaling in response to EGF, acting on AKT1 probably
    through PTEN destabilization and on MAPK8 through ITCH-dependent MAP2K4 inactivation. As a result, may control cell
    growth rate
    Induction: Increased protein expression in neuronal cells in response to Co(2+) or Fe(2+) ions

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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004871signal transducer activity IMP12761501
    GO:0005515protein binding IPI18776082
    GO:0050699WW domain binding IEA--


    NDFIP1 for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for NDFIP1:
     Increased G2M DNA content  Increased number of mitotic ce 

    Animal Models:
         12 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Ndfip1):
     cellular  endocrine/exocrine gland  growth/size  hematopoietic system  homeostasis/metabolism 
     immune system  integument  limbs/digits/tail  liver/biliary system  mortality/aging 
     nervous system  respiratory system 

    NDFIP1 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for NDFIP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    5/7 Interacting proteins for NDFIP1 (Q9BT673 ENSP000002538144) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PTENP604843, ENSP000003610214I2D: score=1 STRING: ENSP00000361021
    SLC11A2P492813, ENSP000002620524I2D: score=1 STRING: ENSP00000262052
    NEDD4P469343, ENSP000003455304I2D: score=4 STRING: ENSP00000345530
    NEDD4LQ96PU53, ENSP000003831994I2D: score=1 STRING: ENSP00000383199
    EGFRP005333, ENSP000002754934I2D: score=1 STRING: ENSP00000275493
    About this table

    Gene Ontology (GO): 5/17 biological process terms (GO ID links to tree view) (see all 17):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0002761regulation of myeloid leukocyte differentiation IEA--
    GO:0002829negative regulation of type 2 immune response IEA--
    GO:0006879cellular iron ion homeostasis IMP18776082
    GO:0007165signal transduction IMP12761501
    GO:0010629negative regulation of gene expression IMP18776082


    NDFIP1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NDFIP1
    Search CenterWatch for drugs/clinical trials and news about NDFIP1 / NFIP1 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NDFIP1 gene: 
    NM_030571.3  

    Unigene Cluster for NDFIP1:

    Nedd4 family interacting protein 1
    Hs.9788  [show with all ESTs]
    Unigene Representative Sequence: AK124884
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000253814(uc003lmj.1 uc003lmi.4) ENST00000509436 ENST00000505614
    ENST00000503388

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    hsa-miR-124* hsa-miR-579 hsa-miR-607 hsa-miR-300 hsa-miR-1258 hsa-miR-138-2* hsa-miR-371-5p hsa-miR-3162-5p
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    Additional cDNA sequence: 

    AB097010.1 AB097037.1 AK075495.1 AK075524.1 AK124884.1 AK315481.1 AL832993.1 AY192728.1 
    BC004317.1 

    21 DOTS entries:

    DT.449327  DT.95085392  DT.100688994  DT.99938336  DT.95085388  DT.452679  DT.100817721  DT.100817715 
    DT.100817717  DT.100817720  DT.97815041  DT.100030769  DT.100843484  DT.120868230  DT.120868232  DT.120868298 
    DT.449325  DT.86840702  DT.91663951  DT.95229339  DT.95085409 

    24/782 AceView cDNA sequences (see all 782):

    AI571822 BM709339 AA906849 AI804890 BM662802 AW172524 AA565211 CB128796 
    AI004733 F04532 BF446208 AI418178 BX411355 CA430792 NM_030571 AV726158 
    BI917292 AI091181 AI148738 BF351892 BM969950 CA312021 AA777115 AA628578 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for NDFIP1    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b
    SP1:                    -                                               -                     
    SP2:                    -                 -                                                   
    SP3:                                                                    -     -               
    SP4:                                                                                          
    SP5:                                                                                          


    ECgene alternative splicing isoforms for NDFIP1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NDFIP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTCTTTCTCA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See NDFIP1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NDFIP1

    SOURCE GeneReport for Unigene cluster: Hs.9788

    UniProtKB/Swiss-Prot: NFIP1_HUMAN, Q9BT67
    Tissue specificity: Widely expressed. Higher levels are detected in cerebellum, pituitary, thalamus, kidney, liver,
    testis, salivary glands and placenta. Also expressed in fetal brain, kidney and lung

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for NDFIP1 gene from 6/20 species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ndfip11 , 5 Nedd4 family interacting protein 11, 5 93.36(n)1
    97.29(a)1
      18 (20.32 cM)5
    651131  NM_022996.11  NP_075372.11 
     384189755 
    chicken
    (Gallus gallus)
    Aves LOC1008586021 NEDD4 family-interacting protein 1-like 85.29(n)
    91.55(a)
      100858602  XM_003642097.1  XP_003642145.1 
    lizard
    (Anolis carolinensis)
    Reptilia NDFIP16
    --
    90(a)
    1 ↔ 1
    2(127016255-127031256)
    African clawed frog
    (Xenopus laevis)
    Amphibia BX853574.12   -- 82.05(n)    BX853574.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufc17e112 wufc17e11 76.42(n)   324047  BC044423.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Ndfip1 Nedd4 family interacting protein 49.38(n)
    44.44(a)
      326197  NM_168743.2  NP_730291.1 


    ENSEMBL Gene Tree for NDFIP1 (if available)
    TreeFam Gene Tree for NDFIP1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NDFIP1 gene
    NDFIP22  
    1 SIMAP similar gene for NDFIP1 using alignment to 1 protein entry:     NFIP1_HUMAN:
    NDFIP2

    NDFIP1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for NDFIP1
    PGOHUM00000239364


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/878 NCBI SNPs in NDFIP1 are shown (see all 878    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs787876011,2
    --136653467(+) GAGGGA/GAAAAA 1 -- int10--------
    rs756334511,2
    --141486376(+) AGGCCA/GACAAA 1 -- us2k10--------
    rs2001471211,2
    C--141486397(+) TTTTTC/TTTTTT 1 -- us2k10--------
    rs113953531,2
    C--141486398(+) TTTTTT/-CAGAG 1 -- us2k1 trp31Minor allele frequency- -:0.00NA 2
    rs750443511,2
    F,--141486433(+) TGTTGC/ACCAGG 1 -- us2k13Minor allele frequency- A:0.13WA NA EA 358
    rs1852232371,2
    --141486444(+) TTGGTC/TTCGAA 1 -- us2k10--------
    rs117432071,2
    C,H--141486469(+) GCTCAC/TGTGAT 1 -- us2k1 tfbs30--------
    rs1140710221,2
    --141486513(+) ACAGAT/CGTGAG 1 -- us2k11Minor allele frequency- C:0.01WA 118
    rs1900532421,2
    --141486811(+) CTCCCA/GGCATG 1 -- us2k10--------
    rs1424878101,2
    --141486854(+) ACAGAC/TATAGA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for NDFIP1 (141488070 - 141534008 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for NDFIP1: --

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    NDFIP1 for disorders           About GeneDecksing

    OMIM gene information: 612050    OMIM disorders: --

    8 diseases for NDFIP1:    About MalaCards
    breast cancer    hypochromic anemia    brain injury    crohn's disease
    anemia    ischemia    cerebritis    neuronitis

    Human Genome Epidemiology (HuGE) Navigator: NDFIP1 (1 document)

    Export disorders for NDFIP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NDFIP1 gene, integrated from 9 sources (see all 28):
    (articles sorted by number of sources associating them with NDFIP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. N4WBP5, a potential target for ubiquitination by the Nedd4 family of proteins, is a novel Golgi-associated protein. (PubMed id 11748237)1, 2, 3 Harvey K.F.... Kumar S. (2002)
    2. Divalent metal transporter 1 (DMT1) regulation by Ndf ip1 prevents metal toxicity in human neurons. (PubMed id 19706893)1, 2, 9 Howitt J....Tan S.S. (2009)
    3. Nedd4 family-interacting protein 1 (Ndfip1) is required for the exosomal secretion of Nedd4 family proteins. (PubMed id 18819914)1, 2, 9 Putz U....Tan S.S. (2008)
    4. Control of the activity of WW-HECT domain E3 ubiquitin ligases by NDFIP proteins. (PubMed id 19343052)1, 2, 9 Mund T. and Pelham H.R. (2009)
    5. Regulation of PTEN/Akt and MAP kinase signaling pathways by the ubiquitin ligase activators Ndfip1 and Ndfip2. (PubMed id 20534535)1, 2 Mund T. and Pelham H.R. (2010)
    6. Regulation of the divalent metal ion transporter DMT1 and iron homeostasis by a ubiquitin-dependent mechanism involving Ndfips and WWP2. (PubMed id 18776082)1, 2 Foot N.J....Kumar S. (2008)
    7. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (2005)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    9. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    10. Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways. (PubMed id 12761501)1, 2 Matsuda A....Sugano S. (2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 80762 HGNC: 17592 AceView: NDFIP1 Ensembl:ENSG00000131507 euGenes: HUgn80762
    ECgene: NDFIP1 H-InvDB: NDFIP1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NDFIP1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NDFIP1 gene:
    Search GeneIP for patents involving NDFIP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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