Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NDC1 Gene

protein-coding   GIFtS: 40
GCID: GC01M054232

NDC1 Transmembrane Nucleoporin

(Previous name: transmembrane protein 48)
(Previous symbol: TMEM48)
  Search for NDC1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
NDC1 Transmembrane Nucleoporin1 2     NET32
TMEM481 2 3 5     Nuclear Division Cycle 1 Homolog2
Transmembrane Protein 481 2 3     Nucleoporin NDC12
Nuclear Division Cycle 1 Homolog (S. Cerevisiae)1     hNDC13

External Ids:    HGNC: 255251   Entrez Gene: 557062   Ensembl: ENSG000000588047   OMIM: 6101155   UniProtKB: Q9BTX13   
ORGUL members:         
NONCODE14:n409072      

Export aliases for NDC1 gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for NDC1 Gene: 
NDC1 (NDC1 transmembrane nucleoporin) is a protein-coding gene, and is affiliated with the lncRNA class.

UniProtKB/Swiss-Prot: NDC1_HUMAN, Q9BTX1
Function: Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of
NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between
the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane

Gene Wiki entry for NDC1 (TMEM48) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for NDC1
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNDC1 promoter sequence
   Search SABiosciences Chromatin IP Primers for NDC1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NDC1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p32.3   Ensembl cytogenetic band:  1p32.3   HGNC cytogenetic band: 1p32.3

NDC1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NDC1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M054232:  view genomic region     (about GC identifiers)

Start:
54,231,133 bp from pter      End:
54,304,533 bp from pter
Size:
73,401 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NDC1_HUMAN, Q9BTX1 (See protein sequence)
Recommended Name: Nucleoporin NDC1  
Size: 674 amino acids; 76305 Da
Subunit: Interacts with the NUP35/NUP53 (By similarity)
Subcellular location: Nucleus, nuclear pore complex. Nucleus membrane; Multi-pass membrane protein. Note=Central
core structure of the nuclear pore complex
Sequence caution: Sequence=BAB14135.1; Type=Erroneous initiation; Sequence=BAC03665.1; Type=Erroneous initiation;
Secondary accessions: Q8NB76 Q9H9T6 Q9NSG3 Q9NSG4 Q9NVZ7
Alternative splicing: 4 isoforms:  Q9BTX1-1   Q9BTX1-2   Q9BTX1-3   Q9BTX1-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NDC1: NX_Q9BTX1

Explore proteomics data for NDC1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9BTX1

  • NDC1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NDC1 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001162023.1  NP_060557.3  

    ENSEMBL proteins: 
     ENSP00000360483   ENSP00000234725   ENSP00000439947   ENSP00000440873  

    Human Recombinant Protein Products for NDC1: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for NDC1
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for NDC1
    GenScript Custom Purified and Recombinant Proteins Services for NDC1
    Novus Biologicals NDC1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005643nuclear pore IDA16600873
    GO:0016021integral to membrane ----
    GO:0031965nuclear membrane IEA--

    NDC1 for ontologies           About GeneDecksing



    NDC1 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for NDC1
    GenScript Custom Superior Antibodies Services for NDC1
    Novus Biologicals NDC1 Antibodies
    Abcam antibodies for NDC1
    Browse Antibodies at Cloud-Clone Corp. 
    Search ThermoFisher Antibodies for NDC1
    Search LSBio for Antibodies for NDC1 

    Assay Products for NDC1: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for NDC1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for NDC1
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp. 
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR019049 Nucleoporin_prot_Ndc1/Nup

    Graphical View of Domain Structure for InterPro Entry Q9BTX1

    ProtoNet protein and cluster: Q9BTX1

    UniProtKB/Swiss-Prot: NDC1_HUMAN, Q9BTX1
    Similarity: Belongs to the NDC1 family


    NDC1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NDC1_HUMAN, Q9BTX1
    Function: Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of
    NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between
    the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0017056structural constituent of nuclear pore IMP16600873
         
    NDC1 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for NDC1:
     Increased HPV18 LCR reporter a  Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for NDC1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for NDC1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NDC1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NDC1 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NDC1
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate NDC1
    SwitchGear 3'UTR luciferase reporter plasmidNDC1 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for NDC1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NDC1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for NDC1
    Sirion Biotech Customized adenovirus for overexpression of NDC1

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for NDC1 (see all 10)
    OriGene ORF clones in mouse, rat for NDC1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for NDC1
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NDC1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NDC1
    Sirion Biotech Customized lentivirus for stable overexpression of NDC1 
                         Customized lentivirus expression plasmids for stable overexpression of NDC1 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for NDC1
    Search LifeMap BioReagents cell lines for NDC1
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NDC1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for NDC1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1RNA transport
    RNA transport

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1         Kegg Pathway  (Kegg details for NDC1):
        RNA transport


    NDC1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NDC1

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    5 Interacting proteins for NDC1 (Q9BTX13 ENSP000003604834) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RIBC2Q9H4K13I2D: score=5 
    COG6Q9Y2V73I2D: score=3 
    DDA1Q9BW613I2D: score=1 
    NUP93ENSP000003106684STRING: ENSP00000310668
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0015031protein transport NAS16600873
    GO:0031081nuclear pore distribution IMP16600873
    GO:0051028mRNA transport IEA--
    GO:0051292nuclear pore complex assembly IMP16600873

    NDC1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NDC1

    Search CenterWatch for drugs/clinical trials and news about NDC1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NDC1 gene (2 alternative transcripts): 
    NM_001168551.1  NM_018087.4  

    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000371429(uc010onu.2 uc001cvs.3 uc001cvt.3 uc009vzk.3 uc010onv.2)
    ENST00000480952 ENST00000234725 ENST00000537333 ENST00000540001
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NDC1
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate NDC1
    SwitchGear 3'UTR luciferase reporter plasmidNDC1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for NDC1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NDC1
    Clone
    Products:
         
    OriGene clones in human, mouse for NDC1 (see all 10)
    OriGene ORF clones in mouse, rat for NDC1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for NDC1
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NDC1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NDC1
    Sirion Biotech Customized lentivirus for stable overexpression of NDC1 
                         Customized lentivirus expression plasmids for stable overexpression of NDC1 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for NDC1
    OriGene qSTAR qPCR primer pairs in human, mouse for NDC1
    Search SABiosciences RT2 qPCR Primer Assays in human, mouse, rat NDC1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NDC1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NDC1

    24/281 AceView cDNA sequences (see all 281):

    AI627886 AU118119 BM564277 AA938330 AW270990 CA313757 BQ690946 Z40213 
    AU130743 NM_018087 AI688930 BM458694 BF111699 AK025450 BU429008 AK001269 
    AU131100 BX957089 BX476828 AA687117 AA767245 BQ685754 AU131541 CB117685 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for NDC1 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11a · 11b ^ 12 ^ 13a · 13b · 13c ^ 14 ^ 15 ^ 16 ^ 17 ^ 18a · 18b ^
    SP1:                                                                                                                                -                           
    SP2:                                                                                                                    -     -     -                           
    SP3:                    -                                                                                                           -                           
    SP4:                                                                                            -     -     -                       -                           
    SP5:                                                                                                                                                            

    ExUns: 19a · 19b · 19c
    SP1:                  
    SP2:                  
    SP3:                  
    SP4:                  
    SP5:                  


    ECgene alternative splicing isoforms for NDC1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NDC1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    NDC1 Expression
    About this image


    See NDC1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NDC1
        SABiosciences Custom PCR Arrays for NDC1
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for NDC1
    OriGene qSTAR qPCR primer pairs in human, mouse for NDC1
    Search SABiosciences RT2 qPCR Primer Assays in human, mouse, rat NDC1
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NDC1
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NDC1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NDC1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for NDC1 gene from 7/16 species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmem481 , 5 transmembrane protein 481, 5 86.11(n)1
    87.5(a)1
      4 (50.18 cM)5
    727871  NM_028355.31  NP_082631.11 
     1073677845 
    chicken
    (Gallus gallus)
    Aves TMEM481 transmembrane protein 48 69.74(n)
    70.81(a)
      772284  XM_001235441.2  XP_001235442.2 
    lizard
    (Anolis carolinensis)
    Reptilia TMEM486
    transmembrane protein 48
    66(a)
    1 ↔ 1
    4(115814024-115841806)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.142112 Xenopus laevis transcribed sequence with weak similarity more 78.66(n)    BU912532.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufk93f042 wufk93f04 75.16(n)   335236  BC053915.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG58571 CG5857 38.24(n)
    25.64(a)
      42825  NM_142934.3  NP_651191.1 
    worm
    (Caenorhabditis elegans)
    Secernentea npp-226
    Nucleoporin ndc-1
    23(a)
    1 ↔ 1
    V(11730992-11733479)


    ENSEMBL Gene Tree for NDC1 (if available)
    TreeFam Gene Tree for NDC1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1430 SNPs in NDC1 are shown (see all 1430)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1908063651,2
    --54230676(+) CATCTC/TTGTTT 3 -- int10--------
    rs11812051,2
    C,F,H--54230713(-) AAGCCA/GTAGTT 3 -- int112Minor allele frequency- G:0.05NA MN NS EA WA 1406
    rs1500773601,2
    --54230754(+) AACTAA/CCTAGA 3 -- int10--------
    rs1383781521,2
    --54230759(+) CCTAGA/GGGTGA 3 -- int10--------
    rs1489160031,2
    --54230786(+) AGTAAC/TGTTGA 3 -- int10--------
    rs1435928531,2
    C--54230796(+) ACAGAC/TGTAAC 3 -- int10--------
    rs1829838461,2
    --54230960(+) TACCAC/TGAAAC 3 -- int10--------
    rs1872885571,2
    --54231129(+) ACACAA/CATATT 3 -- int10--------
    rs1913219451,2
    --54231131(+) ACACAC/TATTTC 3 -- spd10--------
    rs1826238471,2
    --54231247(+) TGACAC/TACCAA 3 -- nc-transcript-variantut310--------

    HapMap Linkage Disequilibrium report for NDC1 (54231133 - 54304533 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for NDC1: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing NDC1
    DNA2.0 Custom Variant and Variant Library Synthesis for NDC1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    NDC1 for disorders           About MalaCards
    OMIM gene information: 610115    OMIM disorders: --


    NDC1 for disorders           About GeneDecksing


    Export disorders for NDC1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NDC1 gene, integrated from 9 sources (see all 25):
    (articles sorted by number of sources associating them with NDC1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Nuclear membrane proteins with potential disease links found by subtractive proteomics. (PubMed id 12958361)1, 2, 3 Schirmer E.C....Gerace L. (2003)
    2. Topology of yeast Ndc1p: predictions for the human NDC1/NET3 homologue. (PubMed id 16779818)1, 3 Lau C.K....Forbes D.J. (2006)
    3. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    4. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    5. The conserved transmembrane nucleoporin NDC1 is required for nuclear pore complex assembly in vertebrate cells. (PubMed id 16600873)1, 2 Mansfeld J.... Antonin W. (2006)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    8. Why do cellular proteins linked to K63-polyubiquitin c hains not associate with proteasomes? (PubMed id 23314748)1 Nathan J.A....Goldberg A.L. (2013)
    9. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)
    10. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55706 HGNC: 25525 AceView: FLJ10407 Ensembl:ENSG00000058804 euGenes: HUgn55706
    ECgene: NDC1 Kegg: 55706 H-InvDB: NDC1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NDC1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NDC1 gene:
    Search GeneIP for patents involving NDC1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for NDC1  
     OriGene qPCR primer pairs and template standards for NDC1   OriGene Protein Over-expression Lysate for NDC1  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for NDC1  
     OriGene qSTAR qPCR primer pairs in human, mouse for NDC1   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for NDC1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for NDC1   OriGene Custom Protein Services for NDC1  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NDC1
     QIAGEN SeqTarget long-range PCR primers for resequencing NDC1
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NDC1
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NDC1
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NDC1
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NDC1
     GenScript Custom Purified and Recombinant Proteins Services for NDC1 GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for NDC1
     GenScript Custom Assay Services for NDC1 GenScript Custom Superior Antibodies Services for NDC1
     GenScript Custom overexpressing Cell Line Services for NDC1 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Search Regulatory tfbs for NDC1
     Search Chromatin IP Primers for NDC1
     Search RT2 qPCR Primer Assays in human, mouse, rat NDC1
     Search GNC Networks for NDC1
     SABiosciences Custom PCR Arrays for NDC1
     Search Tocris compounds for NDC1
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     NDC1 antibodies
     NDC1 lysates
     Antibodies for NDC1
     See all of Abcam's Antibodies, Kits and Proteins for NDC1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.
     Search LifeMap BioReagents cell lines for NDC1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NDC1
     SwitchGear 3'UTR luciferase reporter plasmids for NDC1
     SwitchGear Promoter luciferase reporter plasmids for NDC1
     Search ThermoFisher Antibodies for NDC1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NDC1
     inGenious Targeting Laboratory - Custom generated mouse model solutions for NDC1
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for NDC1
    Customized:
     lentivirus for stable overexpression of NDC1
     lentivirus expression plasmids for stable overexpression of NDC1
     adenovirus for overexpression of NDC1
     Search LSBio for Antibodies for NDC1
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      NDC1 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4