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NCR2 Gene

protein-coding   GIFtS: 62
GCID: GC06P041303

Natural Cytotoxicity Triggering Receptor 2

(Previous name: lymphocyte antigen 95 (activating NK-receptor; NK-p44))
(Previous symbol: LY95)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Natural Cytotoxicity Triggering Receptor 21 2     CD3362
LY951 2 3 5     dJ149M18.12
Lymphocyte Antigen 95 (Activating NK-Receptor; NK-P44)1 2     Lymphocyte Antigen 95 Homolog (Activating NK-Receptor; NK-P44)2
Natural Killer Cell P44-Related Protein2 3     NK Cell Activating Receptor (NKp44)2
NK-p442 3     NKp443
NK Cell-Activating Receptor2 3     CD336 Antigen3
NKP442 5     Lymphocyte Antigen 95 Homolog3

External Ids:    HGNC: 67321   Entrez Gene: 94362   Ensembl: ENSG000000962647   OMIM: 6045315   UniProtKB: O959443   

Export aliases for NCR2 gene to outside databases

Previous GC identifers: GC06P041299 GC06P041350 GC06P041411 GC06P041022


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for NCR2 Gene:
NCR2 (natural cytotoxicity triggering receptor 2) is a protein-coding gene. Diseases associated with NCR2 include epidermodysplasia verruciformis, and cytomegalovirus infection. GO annotations related to this gene include transmembrane signaling receptor activity. An important paralog of this gene is TREML4.

UniProtKB/Swiss-Prot: NCTR2_HUMAN, O95944
Function: Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural
killer (NK) cells to mediate tumor cell lysis

Gene Wiki entry for NCR2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000006.12  NC_018917.2  NT_007592.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the NCR2 gene promoter:
         AREB6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNCR2 promoter sequence
   Search Chromatin IP Primers for NCR2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NCR2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.1   Ensembl cytogenetic band:  6p21.1   HGNC cytogenetic band: 6p21.1

NCR2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NCR2 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P041303:  view genomic region     (about GC identifiers)

Start:
41,303,393 bp from pter      End:
41,318,625 bp from pter
Size:
15,233 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: NCTR2_HUMAN, O95944 (See protein sequence)
Recommended Name: Natural cytotoxicity triggering receptor 2 precursor  
Size: 276 amino acids; 30677 Da
Subunit: Interacts with TYROBP/DAP12. Interacts with KMT2E isoform NKp44L
1 PDB 3D structure from and Proteopedia for NCR2:
1HKF (3D)    
Secondary accessions: Q9H562 Q9H563 Q9H564 Q9UMT1 Q9UMT2
Alternative splicing: 3 isoforms:  O95944-1   O95944-2   O95944-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NCR2: NX_O95944

Explore proteomics data for NCR2 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn180

  • See NCR2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001186438.1  NP_001186439.1  NP_004819.2  

    ENSEMBL proteins: 
     ENSP00000362175   ENSP00000362181   ENSP00000362178  
    Reactome Protein details: O95944

    NCR2 Human Recombinant Protein Products:

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    NCR2 Antibody Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    CD: CD molecules
    VSET: Immunoglobulin superfamily / V-set domain containing

    4 InterPro protein domains:
     IPR013783 Ig-like_fold
     IPR013106 Ig_V-set
     IPR007110 Ig-like_dom
     IPR003599 Ig_sub

    Graphical View of Domain Structure for InterPro Entry O95944

    ProtoNet protein and cluster: O95944

    2 Blocks protein domains:
    IPB003599 Immunoglobulin subtype
    IPB013106 Immunoglobulin V-set


    UniProtKB/Swiss-Prot: NCTR2_HUMAN, O95944
    Similarity: Belongs to the natural cytotoxicity receptor (NCR) family
    Similarity: Contains 1 Ig-like (immunoglobulin-like) domain


    NCR2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NCTR2_HUMAN, O95944
    Function: Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural
    killer (NK) cells to mediate tumor cell lysis

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004888transmembrane signaling receptor activity TAS10049942
    GO:0005515protein binding ----
         
    NCR2 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for NCR2:
     Decreased Salmonella enterica  

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NCR2
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NCR2
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    miRNA
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    1 qRT-PCR Assays for microRNA that regulate NCR2:
    hsa-miR-590-3p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Sino Biological Human cDNA Clone for NCR2
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NCR2

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NCTR2_HUMAN, O95944: Cell membrane; Single-pass type I membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    extracellular2
    mitochondrion2

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0005887integral component of plasma membrane TAS10049942

    NCR2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for NCR2 About    
    See pathways by source

    SuperPathContained pathways About
    1Immune response Role of DAP12 receptors in NK cells
    Immune response Role of DAP12 receptors in NK cells0.33
    Natural killer cell mediated cytotoxicity0.31
    2Signaling by FGFR
    DAP12 interactions0.89

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for NCR2
        Immune response Role of DAP12 receptors in NK cells


    1 Reactome Pathway for NCR2
        DAP12 interactions


    1 Kegg Pathway  (Kegg details for NCR2):
        Natural killer cell mediated cytotoxicity


    NCR2 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NCR2
    Interactions:

        GeneGlobe Interaction Network for NCR2

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for NCR2 (O959443 ENSP000003621814) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TYROBPO439143, ENSP000002626294I2D: score=2 STRING: ENSP00000262629
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006968cellular defense response TAS10049942
    GO:0007165signal transduction TAS10049942
    GO:0045087innate immune response TAS--

    NCR2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NCR2 (NCTR2)

    1 Novoseek inferred chemical compound relationship for NCR2 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tyrosine 0 5 14707061 (5)



    NCR2 for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for NCR2 gene (3 alternative transcripts): 
    NM_001199509.1  NM_001199510.1  NM_004828.3  

    Unigene Cluster for NCR2:

    Natural cytotoxicity triggering receptor 2
    Hs.194721  [show with all ESTs]
    Unigene Representative Sequence: NM_001199509
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000373083(uc003oqj.2 uc003oqi.2) ENST00000373089(uc003oqh.2)
    ENST00000373086
    miRNA
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    1 qRT-PCR Assays for microRNA that regulate NCR2:
    hsa-miR-590-3p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Primer
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    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat NCR2
      QuantiTect SYBR Green Assays in human, mouse, rat NCR2
      QuantiFast Probe-based Assays in human, mouse, rat NCR2

    Additional mRNA sequence: 

    AJ010099.1 AJ010100.1 

    3 DOTS entries:

    DT.121308488  DT.91668614  DT.92013000 

    5 AceView cDNA sequences:

    BV199159 AJ010099 AJ010100 NM_004828 AJ225109 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for NCR2    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6
    SP1:                                          
    SP2:                    -                     


    ECgene alternative splicing isoforms for NCR2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NCR2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACTGATCTGA
    NCR2 Expression
    About this image


    NCR2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Blood (Hematopoietic System)    fully expand to see all 2 entries
             Natural killer-like cells
             bone marrow   
     
     Bone (Muscoskeletal System)
             bone marrow   
    NCR2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NCR2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.194721

    UniProtKB/Swiss-Prot: NCTR2_HUMAN, O95944
    Tissue specificity: Selectively expressed by activated NK cells and by in vitro cultured (i.e. activated) TCRg/d
    lymphoid cells

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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      --

    ENSEMBL Gene Tree for NCR2 (if available)
    TreeFam Gene Tree for NCR2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for NCR2 gene
    TREML42  
    1 SIMAP similar gene for NCR2 using alignment to 1 protein entry:     NCTR2_HUMAN:
    TREML4

    NCR2 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for NCR2
    PGOHUM00000243620


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NCR2 (see all 474)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs6406901,2
    H--41301546(+) GTGCAG/CATGGT 3 -- us2k14Minor allele frequency- C:0.00NS EA 420
    rs6377771,2
    H--41301573(+) CCCTAG/TGGTGC 3 -- us2k14Minor allele frequency- T:0.00NS EA 416
    rs734353561,2
    C,F--41301586(+) AAGGCC/TCCAAG 3 -- us2k12Minor allele frequency- T:0.06WA 120
    rs734353571,2
    C,F--41301655(+) GGGGCA/GGATTC 3 -- us2k12Minor allele frequency- G:0.06WA 120
    rs789087561,2
    C,F--41301664(+) TCCCCA/G/TCTTTG 3 -- us2k11NA 120
    rs745725691,2
    C,F--41301681(+) CCTGTC/ACCCTG 3 -- us2k12Minor allele frequency- A:0.06WA 120
    rs6382801,2
    H--41301707(+) CTCTGA/TCACAG 3 -- us2k14Minor allele frequency- T:0.00NS EA 420
    rs93573551,2
    C,F,A,H--41301735(+) CTGGCT/CGCAGG 3 -- us2k116Minor allele frequency- C:0.44NA NS EA WA 918
    rs737332121,2
    C,F--41301736(+) TGGCTG/ACAGGC 3 -- us2k12Minor allele frequency- A:0.04WA 120
    rs6386691,2
    H--41301756(+) ACACAG/CCTAGT 3 -- us2k14Minor allele frequency- C:0.00NS EA 420

    HapMap Linkage Disequilibrium report for NCR2 (41303393 - 41318625 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for NCR2:    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv6836n71CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NCR2
    DNA2.0 Custom Variant and Variant Library Synthesis for NCR2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 604531    OMIM disorders: --

    Selected diseases for NCR2 (see all 29):    
    About MalaCards
    epidermodysplasia verruciformis    cytomegalovirus infection    vaccinia    pregnancy loss
    newcastle disease    allergic contact dermatitis    contact dermatitis    kaposi's sarcoma
    peritonitis    colon adenocarcinoma    acute myeloid leukemia    herpes simplex
    crohn's disease    influenza    cervical cancer    myeloid leukemia
    sarcoma    dermatitis    hepatitis b    periodontitis

    1 disease from the University of Copenhagen DISEASES database for NCR2:
    Epidermodysplasia verruciformis

    NCR2 for disorders           About GeneDecksing

    2 Novoseek inferred disease relationships for NCR2 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    virus infection 31.3 1 16474130 (1)
    tumors 31.2 6 10049942 (2), 11606250 (1), 19531227 (1), 18092004 (1) (see all 5)

    Genetic Association Database (GAD): NCR2
    Human Genome Epidemiology (HuGE) Navigator: NCR2 (1 document)

    Export disorders for NCR2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NCR2 gene, integrated from 10 sources (see all 84):
    (articles sorted by number of sources associating them with NCR2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. NKp44, a triggering receptor involved in tumor cell lysis by activated human natural killer cells, is a novel member of the immunoglobulin superfamily. (PubMed id 10049942)1, 2, 3, 9 Cantoni C.... Biassoni R. (J. Exp. Med. 1999)
    2. Identification of a cellular ligand for the natural cytotoxicity receptor NKp44. (PubMed id 23958951)1, 2 Baychelier F....Vieillard V. (Blood 2013)
    3. Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease. (PubMed id 21116278)1, 4 Furney S.J.... . (Mol. Psychiatry 2011)
    4. The three-dimensional structure of the human NK cell receptor NKp44, a triggering partner in natural cytotoxicity. (PubMed id 12791260)1, 2 Cantoni C.... Bordo D. (Structure 2003)
    5. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (Nature 2003)
    6. NKp44 triggers NK cell activation through DAP12 association that is not influenced by a putative cytoplasmic inhibitory sequence. (PubMed id 14707061)1, 9 Campbell K.S....Catina T.L. (J. Immunol. 2004)
    7. Expression analysis of the ligands for the Natural Killer cell receptors NKp30 and NKp44. (PubMed id 18092004)1, 9 Byrd A....Watzl C. (PLoS ONE 2007)
    8. Human NK cytotoxicity against porcine cells is triggered by NKp44 and NKG2D. (PubMed id 16210654)1, 9 Forte P....Seebach J.D. (J. Immunol. 2005)
    9. Expressions of natural cytotoxicity receptors and NKG2D on decidual natural killer cells in patients having spontaneous abortions. (PubMed id 18023431)1, 9 Zhang Y....Lin Q. (Fertil. Steril. 2008)
    10. Paradoxic inhibition of human natural interferon-producing cells by the activating receptor NKp44. (PubMed id 15941912)1, 9 Fuchs A....Colonna M. (Blood 2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 9436 HGNC: 6732 AceView: NCR2 Ensembl:ENSG00000096264 euGenes: HUgn9436
    ECgene: NCR2 Kegg: 9436 H-InvDB: NCR2

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for NCR2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NCR2 gene:
    Search GeneIP for patents involving NCR2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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