Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



NCOR2 Gene

protein-coding   GIFtS: 66
GCID: GC12M124808

Nuclear Receptor Corepressor 2

(Previous name: nuclear receptor co-repressor 2)
  See NCOR2-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Nuclear Receptor Corepressor 21 2     Nuclear Receptor Co-Repressor 21
SMRT2 3 5     SMRTE2
Thyroid-, Retinoic-Acid-Receptor-Associated Corepressor2 3     SMRTE-tau2
CTG262 3     TNRC142
N-CoR22 3     TRAC-12
SMAP2702 3     TRAC12
TRAC2 3     Silencing Mediator For Retinoid And Thyroid Hormone Receptors2
CTG Repeat Protein 262 3     Silencing Mediator Of Retinoic Acid And Thyroid Hormone Receptor3
T3 Receptor-Associating Factor2 3     

External Ids:    HGNC: 76731   Entrez Gene: 96122   Ensembl: ENSG000001964987   OMIM: 6008485   UniProtKB: Q9Y6183   

Export aliases for NCOR2 gene to outside databases

Previous GC identifers: GC12M123498 GC12M124551 GC12M123162 GC12M123333 GC12M121771


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for NCOR2 Gene:
This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes.
The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated
co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify
chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this
gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding
different isoforms.(provided by RefSeq, Apr 2011)

GeneCards Summary for NCOR2 Gene:
NCOR2 (nuclear receptor corepressor 2) is a protein-coding gene. Diseases associated with NCOR2 include thyroid hormone resistance syndrome, and cortisol resistance. GO annotations related to this gene include chromatin binding and protein N-terminus binding. An important paralog of this gene is NCOR1.

UniProtKB/Swiss-Prot: NCOR2_HUMAN, Q9Y618
Function: Transcriptional corepressor. Mediates the transcriptional repression activity of some nuclear receptors
by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5
have different affinities for different nuclear receptors. Involved in the regulation BCL6-dependent of the
germinal center (GC) reactions, mainly through the control of the GC B-cells proliferation and survival

Gene Wiki entry for NCOR2 (Nuclear receptor co-repressor 2) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000012.11  NC_018923.2  NT_029419.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the NCOR2 gene promoter:
         ATF-2   AP-2gamma   HEN1   RORalpha1   GATA-6   POU2F1a   AP-2beta   c-Jun   AP-2alpha   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNCOR2 promoter sequence
   Search Chromatin IP Primers for NCOR2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NCOR2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q24   Ensembl cytogenetic band:  12q24.31   HGNC cytogenetic band: 12q24

NCOR2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NCOR2 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M124808:  view genomic region     (about GC identifiers)

Start:
124,808,957 bp from pter      End:
125,052,135 bp from pter
Size:
243,179 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: NCOR2_HUMAN, Q9Y618 (See protein sequence)
Recommended Name: Nuclear receptor corepressor 2  
Size: 2525 amino acids; 274804 Da
Subunit: Forms a large corepressor complex that contains SIN3A/B and histone deacetylases HDAC1 and HDAC2. This
complex associates with the thyroid (TR) and the retinoid acid receptors (RAR) in the absence of ligand, and may
stabilize their interaction with TFIIB. Interacts directly with RARA in the absence of ligand; the interaction
represses RARA activity. Interacts (isoform SMRT) with HDAC10. Interacts with MINT. Component of the N-Cor
repressor complex, at least composed of NCOR1, NCOR2, HDAC3, TBL1X, TBL1R, CORO2A and GPS2. Interacts with
CBFA2T3 and ATXN1L. Interacts with RARB; the interaction is weak and does not repress RARB transactivational
activity. Interacts with HDAC7 and C1D. Interacts with NR4A2; this interaction increases in the absence of PITX3.
Interacts with BCL6 (via the BTB domain), required for BCL6 transcriptional repressor activity on a subset of
target genes. Forms ternary complexes with BCOR and BCL6 on target gene promoters but, on enhancer elements,
interacts with BCL6 and HDAC3 to repress proximal gene expression. May interact with DEAF1
Sequence caution: Sequence=AAB91452.1; Type=Erroneous translation; Note=Wrong choice of CDS; Sequence=AAC50236.1;
Type=Miscellaneous discrepancy; Note=Contaminating sequence. Sequence of unknown origin in the N-terminal part;
Sequence=AAD20946.1; Type=Frameshift; Positions=787, 794; Sequence=BAD92326.1; Type=Erroneous initiation;
Note=Translation N-terminally shortened;
Selected PDB 3D structures from and Proteopedia for NCOR2 (see all 11):
1KKQ (3D)        1R2B (3D)        1XC5 (3D)        2GPV (3D)        2L5G (3D)        2LTP (3D)    
Secondary accessions: O00613 O15416 O15421 Q13354 Q56D06 Q59GM0 Q9Y5U0
Alternative splicing: 5 isoforms:  Q9Y618-1   Q9Y618-2   Q9Y618-3   Q9Y618-4   Q9Y618-5   (Contains only the C-terminal receptor-interacting domain and acts as an antirepressor)

Explore the universe of human proteins at neXtProt for NCOR2: NX_Q9Y618

Explore proteomics data for NCOR2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See NCOR2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001070729.2  NP_001193583.1  NP_006303.4  

    ENSEMBL proteins: 
     ENSP00000384018   ENSP00000384202   ENSP00000400281   ENSP00000391389   ENSP00000405246  
     ENSP00000407357   ENSP00000398963   ENSP00000396044   ENSP00000400687   ENSP00000402808  
     ENSP00000408247   ENSP00000405367   ENSP00000443689   ENSP00000403034   ENSP00000348551  
     ENSP00000380513   ENSP00000385618  
    Reactome Protein details: Q9Y618

    NCOR2 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec
    OriGene Custom Protein Services for NCOR2
    GenScript Custom Purified and Recombinant Proteins Services for NCOR2
    Novus Biologicals NCOR2 Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for NCOR2

     
    Search eBioscience for Proteins for NCOR2 

     
    antibodies-online proteins for NCOR2 (2 products) 

     
    antibodies-online peptides for NCOR2

    NCOR2 Antibody Products:

    EMD Millipore Mono- and Polyclonal Antibodies for the study of NCOR2
    R&D Systems Antibodies for NCOR2
    OriGene Antibodies for NCOR2
    OriGene Custom Antibody Services for NCOR2
    Novus Biologicals NCOR2 Antibodies
    Search for Antibodies for NCOR2 at Abcam
    Cloud-Clone Corp. Antibodies for NCOR2
    ThermoFisher Antibody for NCOR2
    antibodies-online antibodies for NCOR2 (49 products) 

    NCOR2 Assay Products:

    EMD Millipore Kits and Assays for the Analysis of NCOR2
    OriGene Custom Assay Services for NCOR2
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for NCOR2
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for NCOR2
    Cloud-Clone Corp. CLIAs for NCOR2
    Search eBioscience for ELISAs for NCOR2 
    antibodies-online kits for NCOR2 (3 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    3 InterPro protein domains:
     IPR017884 SANT_dom
     IPR001005 SANT/Myb
     IPR009057 Homeodomain-like

    Graphical View of Domain Structure for InterPro Entry Q9Y618

    ProtoNet protein and cluster: Q9Y618

    1 Blocks protein domain: IPB001005 Myb DNA-binding domain

    UniProtKB/Swiss-Prot: NCOR2_HUMAN, Q9Y618
    Domain: The N-terminal region contains repression functions that are divided into three independent repression
    domains (RD1, RD2 and RD3). The C-terminal region contains the nuclear receptor-interacting domains that are
    divided in two separate interaction domains (ID1 and ID2)
    Domain: The two interaction domains (ID) contain a conserved sequence referred to as the CORNR box. This motif is
    required and sufficient to permit binding to unligated TR and RARS. Sequences flanking the CORNR box determine
    nuclear hormone receptor specificity
    Similarity: Belongs to the N-CoR nuclear receptor corepressors family
    Similarity: Contains 2 SANT domains


    Find genes that share domains with NCOR2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NCOR2_HUMAN, Q9Y618
    Function: Transcriptional corepressor. Mediates the transcriptional repression activity of some nuclear receptors
    by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5
    have different affinities for different nuclear receptors. Involved in the regulation BCL6-dependent of the
    germinal center (GC) reactions, mainly through the control of the GC B-cells proliferation and survival
    Induction: Regulated during cell cycle progression

         Genatlas biochemistry entry for NCOR2:
    nuclear hormone receptor co-repressor 2,silencing mediator of retinoic acid and thyroid hormone
    receptors,ubiquitously expressed,recruiting the histone deacytylation complex Sin3A/HDAC1/HDAC2,resulting in
    chromatin remodeling and repression of transcription

         Gene Ontology (GO): Selected molecular function terms (see all 14):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001012RNA polymerase II regulatory region DNA binding ----
    GO:0003677DNA binding IEA--
    GO:0003682chromatin binding IEA--
    GO:0003714transcription corepressor activity IMP12628926
    GO:0005112Notch binding IPI10713164
         
    Find genes that share ontologies with NCOR2           About GenesLikeMe


    Phenotypes:
         5 GenomeRNAi human phenotypes for NCOR2:
     Decreased Tat-dependent transc  Decreased nuclei size in G2M  Decreased p24 protein expressi  Decreased viability 
     Increased 8N DNA content 

         14 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Ncor2):
     adipose tissue  behavior/neurological  cardiovascular system  cellular  craniofacial 
     digestive/alimentary  growth/size/body  hematopoietic system  homeostasis/metabolism  immune system 
     liver/biliary system  mortality/aging  nervous system  skeleton 

    Find genes that share phenotypes with NCOR2           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Ncor2tm1Kjep for NCOR2

       genOway: Develop your customized and physiologically relevant rodent model for NCOR2

    miRNA
    Products:
        
    miRTarBase miRNAs that target NCOR2:
    hsa-mir-10a-5p (MIRT005454), hsa-mir-16-5p (MIRT006651), hsa-mir-130b-5p (MIRT038284), hsa-mir-20a-5p (MIRT050519), hsa-mir-9-5p (MIRT021376), hsa-mir-10b-5p (MIRT005455), hsa-mir-2110 (MIRT035758)

    Block miRNA regulation of human, mouse, rat NCOR2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NCOR2 (see all 53):
    hsa-miR-3607-3p hsa-miR-429 hsa-miR-15a hsa-miR-218-1* hsa-miR-1260b hsa-miR-29a hsa-miR-30d hsa-miR-650
    SwitchGear 3'UTR luciferase reporter plasmidNCOR2 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for NCOR2
    Predesigned siRNA for gene silencing in human, mouse, rat NCOR2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for NCOR2

    Clone
    Products:
         
    OriGene clones in human, mouse for NCOR2 (see all 9)
    OriGene ORF clones in mouse, rat for NCOR2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): NCOR2 (NM_001077261)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NCOR2
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat NCOR2
    Addgene plasmids for NCOR2 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for NCOR2
    Browse ESI BIO Cell Lines and PureStem Progenitors for NCOR2 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NCOR2

    Flow Cytometry
    Products:
       

     
    eBioscience FlowRNA Probe Sets ( VA6-14073) for NCOR2 


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    NCOR2_HUMAN, Q9Y618: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5

    Gene Ontology (GO): Selected cellular component terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000118histone deacetylase complex ----
    GO:0000785chromatin ----
    GO:0005634nucleus IDA--
    GO:0005654nucleoplasm TAS--
    GO:0005730NOT nucleolus IDA--

    Find genes that share ontologies with NCOR2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for NCOR2 About   (see all 28)  
    See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1Notch signaling pathway (KEGG)
    Notch signaling pathway0.84
    Delta-Notch Signaling Pathway0.33
    Notch Signaling Pathway0.84
    Notch Signaling0.30
    2Loss of Function of SMAD2/3 in Cancer
    Transcriptional activity of SMAD2/SMAD3-SMAD4 heterotrimer0.72
    TGFBR1 KD Mutants in Cancer0.60
    Loss of Function of SMAD2/3 in Cancer0.60
    SMAD2/3 MH2 Domain Mutants in Cancer0.60
    Loss of Function of SMAD4 in Cancer0.60
    SMAD2/3 Phosphorylation Motif Mutants in Cancer0.60
    TGFBR2 MSI Frameshift Mutants in Cancer0.60
    SMAD4 MH2 Domain Mutants in Cancer0.60
    3Signaling by NOTCH1 PEST Domain Mutants in Cancer
    Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants0.79
    Constitutive Signaling by NOTCH1 PEST Domain Mutants0.79
    Signaling by NOTCH1 PEST Domain Mutants in Cancer0.79
    Signaling by NOTCH1 t(7;9)(NOTCH1-M1580 K2555) Translocation Mutant0.79
    Signaling by NOTCH1 in Cancer0.79
    FBXW7 Mutants and NOTCH1 in Cancer0.79
    Signaling by NOTCH10.79
    NOTCH1 Intracellular Domain Regulates Transcription0.68
    4Fatty acid, triacylglycerol, and ketone body metabolism
    Fatty acid, triacylglycerol, and ketone body metabolism0.65
    Transcriptional Regulation of White Adipocyte Differentiation0.38
    Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)0.65
    5Development NOTCH1 mediated pathway for NF KB activity modulation
    Development NOTCH1 mediated pathway for NF KB activity modulation0.50
    Transcription Sin3 and NuRD in transcription regulation0.35
    Development Notch Signaling Pathway0.50


    Find genes that share SuperPaths with NCOR2           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 R&D Systems Pathway for NCOR2
        Notch Signaling Pathways

    Selected Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for NCOR2 (see all 7)
        AHR Pathway
    Notch Signaling
    Protein Acetylation and Deacetylation
    Glucocorticoid Receptor Signaling
    Estrogen Pathway

    5 GeneGo (Thomson Reuters) Pathways for NCOR2
        Development NOTCH1-mediated pathway for NF-KB activity modulation
    Transcription Sin3 and NuRD in transcription regulation
    Transcription Ligand-Dependent Transcription of Retinoid-Target genes
    Transcription PPAR Pathway
    Development Notch Signaling Pathway

    Selected BioSystems Pathways for NCOR2 (see all 10)
        Adipogenesis
    Notch Signaling Pathway
    Androgen receptor signaling pathway
    Delta-Notch Signaling Pathway
    Signaling events mediated by HDAC Class I

    Selected Reactome Pathways for NCOR2 (see all 6)
        Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
    NOTCH1 Intracellular Domain Regulates Transcription
    Transcriptional regulation of white adipocyte differentiation
    Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
    Downregulation of SMAD2/3:SMAD4 transcriptional activity


    2 Kegg Pathways  (Kegg details for NCOR2):
        Notch signaling pathway
    Epstein-Barr virus infection

        Pathway & Disease-focused RT2 Profiler PCR Arrays including NCOR2: 
              Estrogen Receptor Signaling in human mouse rat
              Nuclear Receptors & Coregulators in human mouse rat
              Notch Signaling Pathway in human mouse rat
              Adipogenesis in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for NCOR2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for NCOR2 (Q9Y6181, 2, 3 ENSP000003485514) via UniProtKB, MINT, STRING, and/or I2D (see all 838)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053, ENSP000003529804I2D: score=1 STRING: ENSP00000352980
    HIST1H4BP628053I2D: score=1 
    HIST1H4CP628053I2D: score=1 
    HIST1H4DP628053I2D: score=1 
    HIST1H4EP628053I2D: score=1 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 24):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter TAS--
    GO:0001701in utero embryonic development ----
    GO:0003007heart morphogenesis ----
    GO:0006351transcription, DNA-templated TAS--
    GO:0006367transcription initiation from RNA polymerase II promoter TAS--

    Find genes that share ontologies with NCOR2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NCOR2

    1 HMDB Compound for NCOR2    About this table
    CompoundSynonyms CAS #PubMed Ids
    Retinoic acidRetinoate (see all 21)302-79-4--

    Selected Novoseek inferred chemical compound relationships for NCOR2 gene (see all 21)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    retinoid 90.3 99 11435691 (2), 18981260 (2), 11855864 (2), 9092799 (1) (see all 85)
    retinoic acid 77.1 59 9169003 (3), 9717842 (3), 17519355 (2), 17591692 (2) (see all 45)
    steroid 59.5 32 12554786 (2), 17671682 (1), 19183483 (1), 19432593 (1) (see all 26)
    estrogen 59.2 20 17591692 (3), 15802375 (2), 16152593 (2), 20406620 (2) (see all 12)
    4-hydroxytamoxifen 58.8 10 9171229 (4), 14715875 (1), 16990259 (1), 17047084 (1)
    tamoxifen 56.3 41 15802375 (5), 18546531 (5), 20406620 (3), 19904269 (2) (see all 13)
    cyproteroneacetate 52.7 10 11923464 (3), 19223455 (3), 15617028 (1)
    vitamin d 43.4 17 19098224 (3), 17855664 (1), 18981260 (1), 14985122 (1) (see all 9)
    progesterone 41.8 10 20392877 (2), 9488452 (1), 11336882 (1), 16152593 (1) (see all 8)
    zinc 32 4 9819405 (1), 10938135 (1), 14982881 (1), 16042694 (1)



    Find genes that share compounds with NCOR2           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for NCOR2 gene (3 alternative transcripts): 
    NM_001077261.3  NM_001206654.1  NM_006312.5  

    Unigene Cluster for NCOR2:

    Nuclear receptor corepressor 2
    Hs.137510  [show with all ESTs]
    Unigene Representative Sequence: NM_006312
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 25):
    ENST00000405201 ENST00000404621(uc010tax.2 uc010tbc.2) ENST00000429285
    ENST00000418829 ENST00000443451 ENST00000413172 ENST00000464377 ENST00000440337
    ENST00000461081 ENST00000474079 ENST00000440187 ENST00000453428 ENST00000458234(uc001ugj.1)
    ENST00000473999 ENST00000536195 ENST00000493859 ENST00000448614 ENST00000420698(uc001ugk.1)

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat NCOR2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NCOR2 (see all 53):
    hsa-miR-3607-3p hsa-miR-429 hsa-miR-15a hsa-miR-218-1* hsa-miR-1260b hsa-miR-29a hsa-miR-30d hsa-miR-650
    SwitchGear 3'UTR luciferase reporter plasmidNCOR2 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for NCOR2
    Predesigned siRNA for gene silencing in human, mouse, rat NCOR2
    Clone
    Products:
         
    OriGene clones in human, mouse for NCOR2 (see all 9)
    OriGene ORF clones in mouse, rat for NCOR2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): NCOR2 (NM_001077261)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NCOR2
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat NCOR2
    Addgene plasmids for NCOR2 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for NCOR2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NCOR2
      QuantiTect SYBR Green Assays in human, mouse, rat NCOR2
      QuantiFast Probe-based Assays in human, mouse, rat NCOR2
    Flow Cytometry
    Products:
       

     
    eBioscience FlowRNA Probe Sets ( VA6-14073) for NCOR2 

    Additional mRNA sequence: 

    AB209089.1 AF113003.1 AF125672.1 AK127788.1 AY965853.1 BC004326.1 BC020427.1 S83390.1 
    U80750.1 

    Selected DOTS entries (see all 27):

    DT.75145963  DT.99938056  DT.91764966  DT.415951  DT.95275136  DT.95275164  DT.95275180  DT.100891061 
    DT.100891069  DT.99971084  DT.91721025  DT.100891065  DT.220293  DT.427552  DT.121148832  DT.95096710 
    DT.102843151  DT.301927  DT.91764967  DT.91764976  DT.92061083  DT.95275176  DT.95356935  DT.91928104 

    1 AceView cDNA sequence:

    NM_006312 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for NCOR2 (see all 26)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24a · 24b ·
    SP1:                                                                                                                                                            
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 24c ^ 25 ^ 26 ^ 27a · 27b · 27c ^ 28a · 28b · 28c ^ 29a · 29b ^ 30 ^ 31 ^ 32 ^ 33a · 33b · 33c · 33d ^ 34a · 34b · 34c ^ 35 ^ 36a · 36b ^ 37 ^ 38a ·
    SP1:                                                                                                        -     -                                             
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 38b ^ 39 ^ 40a · 40b · 40c · 40d ^ 41a · 41b · 41c · 41d ^ 42a · 42b · 42c · 42d
    SP1:  -                                               -     -                           
    SP2:                                                                                    
    SP3:  -           -     -     -     -                 -     -                           
    SP4:  -                             -                 -     -                           
    SP5:  -                                                                                 


    ECgene alternative splicing isoforms for NCOR2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    NCOR2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCTTCCCCAC
    NCOR2 Expression
    About this image

    NCOR2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NCOR2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.137510

    UniProtKB/Swiss-Prot: NCOR2_HUMAN, Q9Y618
    Tissue specificity: Ubiquitous. High levels of expression are detected in lung, spleen and brain

        Pathway & Disease-focused RT2 Profiler PCR Arrays including NCOR2: 
              Estrogen Receptor Signaling in human mouse rat
              Nuclear Receptors & Coregulators in human mouse rat
              Notch Signaling Pathway in human mouse rat
              Adipogenesis in human mouse rat

    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for NCOR2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NCOR2
    QuantiTect SYBR Green Assays in human, mouse, rat NCOR2
    QuantiFast Probe-based Assays in human, mouse, rat NCOR2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NCOR2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for NCOR2 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ncor21 , 5 nuclear receptor co-repressor 21, 5 83.97(n)1
    88.36(a)1
      5 (63.96 cM)5
    206021  NM_001253904.11  NP_001240833.11 
     1250171535 
    chicken
    (Gallus gallus)
    Aves NCOR21 nuclear receptor corepressor 2 75.16(n)
    76.19(a)
      416815  XM_415107.4  XP_415107.4 
    lizard
    (Anolis carolinensis)
    Reptilia NCOR26
    nuclear receptor corepressor 2
    66(a)
    1 ↔ 1
    LGb(1418065-1575711)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia AL858988.22   -- 78.47(n)    AL858988.2 
    zebrafish
    (Danio rerio)
    Actinopterygii ncor21 nuclear receptor co-repressor 2 61.06(n)
    58.84(a)
      561503  NM_001007032.1  NP_001007033.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Smr6
    Smrter
    12(a)
    1 ↔ 1
    X(12578236-12636477)
    worm
    (Caenorhabditis elegans)
    Secernentea gei-86
    Protein GEI-8, isoform a (gei-8) mRNA, complete cd...
    14(a)
    1 ↔ 1
    III(8111166-8121232) WBGene00001565
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SNT16
    Subunit of the Set3C deacetylase complex that inte...
    14(a)
    1 → many
    III(186489-190169) YCR033W
    rice
    (Oryza sativa)
    Liliopsida AB071804.12   -- 70.81(n)    AB071804.1 


    ENSEMBL Gene Tree for NCOR2 (if available)
    TreeFam Gene Tree for NCOR2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for NCOR2 gene
    NCOR12  
    2 SIMAP similar genes for NCOR2 using alignment to 17 protein entries:     NCOR2_HUMAN (see all proteins):
    NCOR1    NCOR1P1

    Find genes that share paralogs with NCOR2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for NCOR2 (see all 6442)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1502927281,2
    --124623513(+) GACACC/TCTCAC 3 -- ds50010--------
    rs1832010641,2
    --124623521(+) CACCAC/TGGTGT 3 -- ds50010--------
    rs1379357291,2
    C--124623563(+) ACCCTC/TGCCAT 3 -- ds50010--------
    rs17023311,2
    C,F,H--124623612(-) ATGGTG/AAGAGT 3 -- ds500117Minor allele frequency- A:0.03NS NA WA CSA EA 1158
    rs2008852691,2
    C--124623625(+) GGTGT-/ACTCTACT 3 -- ds50010--------
    rs1424530361,2
    --124623664(+) GATACA/GTGGGT 3 -- ds50010--------
    rs1171905871,2
    C,F--124623710(+) CATGAC/TACCCT 3 -- ds50011Minor allele frequency- T:0.01EA 120
    rs1385934941,2
    --124623725(+) ATCATA/GTGAAT 3 -- ds50010--------
    rs588322141,2
    C--124623739(+) GACAC-/TCTCACCATTGT
    GTGAATACCTGACAC
    ATGGG
    3 -- cds10--------
    rs1873138741,2
    --124623752(+) TGAACA/CCATGT 3 -- ds50010--------

    HapMap Linkage Disequilibrium report for NCOR2 (124808957 - 125052135 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for NCOR2 (see all 49):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2746536CNV Deletion23290073
    esv2662504CNV Deletion23128226
    dgv220e201CNV Deletion23290073
    esv2746527CNV Deletion23290073
    esv2746539CNV Deletion23290073
    esv2746532CNV Deletion23290073
    esv2746528CNV Deletion23290073
    esv2670996CNV Deletion23128226
    esv1526249CNV Deletion17803354
    esv2746540CNV Deletion23290073

    Human Gene Mutation Database (HGMD): NCOR2
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NCOR2
    DNA2.0 Custom Variant and Variant Library Synthesis for NCOR2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 600848    OMIM disorders: --

    2 diseases for NCOR2:    
    About MalaCards
    thyroid hormone resistance syndrome    cortisol resistance


    Find genes that share disorders with NCOR2           About GenesLikeMe

    Selected Novoseek inferred disease relationships for NCOR2 gene (see all 13)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    leukemia promyelocytic acute 60.4 3 11585900 (2), 9256429 (1)
    promyelocytic leukemia 48.9 3 10938135 (1), 14982881 (1), 9765306 (1)
    breast cancer 44.8 32 19904269 (3), 15802375 (3), 20392877 (2), 18546531 (2) (see all 15)
    leukemogenesis 43.2 2 11929748 (1), 11585900 (1)
    endometrial carcinoma 30.4 1 14751175 (1)
    prostate cancer 24.9 10 15300237 (3), 15948728 (2), 17804755 (2), 16373395 (1) (see all 5)
    leukemia 15.6 2 10611298 (1), 16042694 (1)
    lymphoma non-hodgkins 9.26 5 15930272 (3), 9753732 (1)
    cancer 7.71 1 11336882 (1)
    necrosis 0 1 15811852 (1)

    Genetic Association Database (GAD): NCOR2
    Human Genome Epidemiology (HuGE) Navigator: NCOR2 (13 documents)

    Export disorders for NCOR2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for NCOR2 gene, integrated from 10 sources (see all 386):
    (articles sorted by number of sources associating them with NCOR2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A transcriptional co-repressor that interacts with nuclear hormone receptors. (PubMed id 7566127)1, 2, 3, 9 Chen J.D. and Evans R.M. (Nature 1995)
    2. Identification of TRACs (T3 receptor-associating cofactors), a family of cofactors that associate with, and modulate the activity of, nuclear hormone receptors. (PubMed id 8813722)1, 2, 3 Sande S. and Privalsky M.L. (Mol. Endocrinol. 1996)
    3. Alternative mRNA splicing of SMRT creates functional diversity by generating corepressor isoforms with different affinities for different nuclear receptors. (PubMed id 15632172)1, 2, 9 Goodson M.L.... Privalsky M.L. (J. Biol. Chem. 2005)
    4. Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3. (PubMed id 10944117)1, 2, 9 Li J.... Wong J. (EMBO J. 2000)
    5. Retinoic acid receptors beta and gamma do not repress, but instead activate target gene transcription in both the absence and presence of hormone ligand. (PubMed id 12554770)1, 2, 9 Hauksdottir H.... Privalsky M.L. (Mol. Endocrinol. 2003)
    6. Genetic predictors of interindividual variability in hepatic CYP3A4 expression. (PubMed id 19934400)1, 4, 9 Lamba V....Schuetz E.G. (J. Pharmacol. Exp. Ther. 2010)
    7. Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort. (PubMed id 19183483)1, 4, 9 Haiman C.A....Press M.F. (BMC Cancer 2009)
    8. A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40- repeat protein linked to deafness. (PubMed id 10809664)1, 2, 9 Guenther M.G....Shiekhattar R. (Genes Dev. 2000)
    9. SMRTe, a silencing mediator for retinoid and thyroid hormone receptors-extended isoform that is more related to the nuclear receptor corepressor. (PubMed id 10097068)1, 2, 9 Park E.J.... Chen J.D. (Proc. Natl. Acad. Sci. U.S.A. 1999)
    10. Genetic associations of variants in genes encoding HIV-dependency factors required for HIV-1 infection. (PubMed id 21083371)1, 4 Chinn L.W....O'Brien S.J. (J. Infect. Dis. 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 9612 HGNC: 7673 AceView: NCOR2 Ensembl:ENSG00000196498 euGenes: HUgn9612
    ECgene: NCOR2 Kegg: 9612 H-InvDB: NCOR2

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for NCOR2 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for NCOR2 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for NCOR2 gene:
    Search GeneIP for patents involving NCOR2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
    About This Section

    TryGeneCards Plus

     EMD Millipore Kits and Assays for the Analysis of NCOR2
     Browse Small Molecules at EMD Millipore
     EMD Millipore Mono- and Polyclonal Antibodies for the study of NCOR2
     Browse Purified and Recombinant Proteins at EMD Millipore
     
     EMD Millipore genomic analysis products

      
     Antibodies for NCOR2 (NCOR2)   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for NCOR2   OriGene RNAi products in human, mouse, rat for NCOR2  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for NCOR2  
     OriGene qSTAR qPCR primer pairs in human, mouse for NCOR2   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for NCOR2   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for NCOR2   OriGene Custom Protein Services for NCOR2  

     
     
     Block miRNA regulation of human, mouse, rat NCOR2 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing NCOR2
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NCOR2 Predesigned siRNA for gene silencing in human, mouse, rat NCOR2
     QuantiFast Probe-based Assays in human, mouse, rat NCOR2 QuantiTect SYBR Green Assays in human, mouse, rat NCOR2
     PCR Arrays including human, mouse, rat NCOR2 Search Chromatin IP Primers for NCOR2
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NCOR2  GeneGlobe Interaction Network for NCOR2
     Regulatory tfbs in NCOR2 promoter
     GenScript Custom Purified and Recombinant Proteins Services for NCOR2 GenScript cDNA clones with any tag delivered in your preferred vector for NCOR2
     GenScript Custom Assay Services for NCOR2 GenScript Custom overexpressing Cell Line Services for NCOR2
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for NCOR2
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     NCOR2 antibodies
     NCOR2 proteins
     Search for Antibodies for NCOR2 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for NCOR2
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for NCOR2
     Antibodies for NCOR2
     ELISAs for NCOR2
     CLIAs for NCOR2



     Browse ESI BIO Cell Lines and PureStem Progenitors for NCOR2
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NCOR2
     SwitchGear 3'UTR luciferase reporter plasmids for NCOR2
     SwitchGear Promoter luciferase reporter plasmids for NCOR2
     ThermoFisher Antibody for NCOR2
     Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat NCOR2
     Browse compounds at ApexBio
     Addgene plasmids for NCOR2
      Search eBioscience for proteins for NCOR2
      Search eBioscience for elisas for NCOR2
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for NCOR2
     antibodies-online antibodies for NCOR2 (49 products)
     antibodies-online kits for NCOR2 (3 products)
     antibodies-online peptides for NCOR2
     antibodies-online proteins for NCOR2 (2 products)
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      NCOR2 gene at Home site.
    Version: 3.12.258 10 Dec 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4