Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



NCOA2 Gene

protein-coding   GIFtS: 68
GCID: GC08M071016

Nuclear Receptor Coactivator 2

  See NCOA2-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Nuclear Receptor Coactivator 21 2     GRIP12 5
TIF22 3 5     SRC22 5
Class E Basic Helix-Loop-Helix Protein 752 3     KAT13C2
Transcriptional Intermediary Factor 22 3     Glucocorticoid Receptor-Interacting Protein-12
NCoA-22 3     BHLHE753
bHLHe752 3     EC 2.3.1.488
hTIF22 3     

External Ids:    HGNC: 76691   Entrez Gene: 104992   Ensembl: ENSG000001403967   OMIM: 6019935   UniProtKB: Q155963   

Export aliases for NCOA2 gene to outside databases

Previous GC identifers: GC08M070125 GC08M070964 GC08M070747 GC08M071074 GC08M071186 GC08M066517


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for NCOA2 Gene:
The NCOA2 gene encodes nuclear receptor coactivator 2, which aids in the function of nuclear hormone receptors.
Nuclear hormone receptors are conditional transcription factors that play important roles in various aspects of
cell growth, development, and homeostasis by controlling expression of specific genes. Members of the nuclear
hormone receptor superfamily, which includes the 5 steroid receptors and class II nuclear receptors (see below),
are structurally characterized by 3 distinct domains: an N-terminal transcriptional activation domain, a central
DNA-binding domain, and a C-terminal hormone-binding domain. Before the binding of hormone, steroid receptors,
which are sometimes called class I of the nuclear hormone receptor family, remain inactive in a complex with
heat-shock protein-90 (MIM 140571) and other stress family proteins. Binding of hormone induces critical
conformational changes in steroid receptors that cause them to dissociate from the inhibitory complex, bind as
homodimers to specific DNA enhancer elements associated with target genes, and modulate that gene's
transcription. After binding to enhancer elements, transcription factors require transcriptional coactivator
proteins to mediate their stimulation of transcription initiation (Hong et al., 1997 (PubMed 9111344)).(supplied
by OMIM, Nov 2010)

GeneCards Summary for NCOA2 Gene:
NCOA2 (nuclear receptor coactivator 2) is a protein-coding gene. Diseases associated with NCOA2 include spindle cell rhabdomyosarcoma, and partial androgen insensitivity syndrome. GO annotations related to this gene include transcription coactivator activity and chromatin binding. An important paralog of this gene is NCOA3.

UniProtKB/Swiss-Prot: NCOA2_HUMAN, Q15596
Function: Transcriptional coactivator for steroid receptors and nuclear receptors. Coactivator of the steroid
binding domain (AF-2) but not of the modulating N-terminal domain (AF-1). Required with NCOA1 to control energy
balance between white and brown adipose tissues

Gene Wiki entry for NCOA2 (Nuclear receptor coactivator 2) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000008.10  NT_008183.20  NC_018919.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the NCOA2 gene promoter:
         COUP-TF1   FOXD3   COUP   Nkx2-5   HNF-4alpha2   HNF-4alpha1   PPAR-gamma1   COUP-TF   PPAR-gamma2   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for NCOA2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NCOA2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q13.3   Ensembl cytogenetic band:  8q13.3   HGNC cytogenetic band: 8q13.3

NCOA2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NCOA2 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M071016:  view genomic region     (about GC identifiers)

Start:
71,021,997 bp from pter      End:
71,316,040 bp from pter
Size:
294,044 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: NCOA2_HUMAN, Q15596 (See protein sequence)
Recommended Name: Nuclear receptor coactivator 2  
Size: 1464 amino acids; 159157 Da
Subunit: Present in a complex containing CARM1 and EP300/P300, and interacts with CARM1 and NR3C2 (By similarity).
Present in a complex containing NCOA3, IKKA, IKKB, IKBKG and CREBBP. Interacts (via C-terminus) with CREBBP.
Interacts with HIF1A, NCOA1, APEX and NR3C1. Interacts with CASP8AP2 and TTLL5/STAMP. Interacts with ESR1, RARA
and RXRA. Interacts with PSMB9 and DDX5
Selected PDB 3D structures from and Proteopedia for NCOA2 (see all 80):
1GWQ (3D)        1GWR (3D)        1M2Z (3D)        1MV9 (3D)        1MVC (3D)        1MZN (3D)    
Secondary accessions: Q14CD2

Explore the universe of human proteins at neXtProt for NCOA2: NX_Q15596

Explore proteomics data for NCOA2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • 2 DME Specific Peptides for NCOA2 (Q15596)
     LEALDGFF  SHTFNCRML 


    See NCOA2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_006531.1  
    ENSEMBL proteins: 
     ENSP00000399968   ENSP00000430148   ENSP00000429132   ENSP00000430348   ENSP00000430850  
     ENSP00000267974  
    Reactome Protein details: Q15596

    NCOA2 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for NCOA2
    OriGene Custom MassSpec
    OriGene Custom Protein Services for NCOA2
    GenScript Custom Purified and Recombinant Proteins Services for NCOA2
    Novus Biologicals NCOA2 Protein
    Novus Biologicals NCOA2 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for NCOA2

     
    Search eBioscience for Proteins for NCOA2 

     
    antibodies-online proteins for NCOA2 (2 products) 

     
    antibodies-online peptides for NCOA2

    NCOA2 Antibody Products:

    EMD Millipore Mono- and Polyclonal Antibodies for the study of NCOA2
    R&D Systems Antibodies for NCOA2
    OriGene Antibodies for NCOA2
    OriGene Custom Antibody Services for NCOA2
    Novus Biologicals NCOA2 Antibodies
    Abcam antibodies for NCOA2
    Cloud-Clone Corp. Antibodies for NCOA2
    ThermoFisher Antibodies for NCOA2
    antibodies-online antibodies for NCOA2 (52 products) 

    NCOA2 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for NCOA2
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for NCOA2
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for NCOA2
    Cloud-Clone Corp. CLIAs for NCOA2
    Search eBioscience for ELISAs for NCOA2 
    antibodies-online kits for NCOA2 (6 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    KAT: Chromatin-modifying enzymes / K-acetyltransferases
    bHLH: Basic helix-loop-helix proteins

    Selected InterPro protein domains (see all 11):
     IPR008955 Src1_rcpt_coact
     IPR010011 DUF1518
     IPR014935 SRC-1
     IPR001610 PAC
     IPR014920 Nuc_rcpt_coact_Ncoa-typ

    Graphical View of Domain Structure for InterPro Entry Q15596

    ProtoNet protein and cluster: Q15596

    4 Blocks protein domains:
    IPB000014 PAS domain
    IPB001092 Basic helix-loop-helix dimerization domain bHLH
    IPB001610 PAC motif
    IPB010011 Protein of unknown function DUF1518


    UniProtKB/Swiss-Prot: NCOA2_HUMAN, Q15596
    Domain: Contains four Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs. The LXXLL motifs are essential for the association with
    nuclear receptors and are, at least in part, functionally redundant
    Domain: The LLXXLXXXL motif is involved in transcriptional coactivation and CREBBP/CBP binding
    Domain: Contains 2 C-terminal transcription activation domains (AD1 and AD2) that can function independently
    Similarity: Belongs to the SRC/p160 nuclear receptor coactivator family
    Similarity: Contains 1 bHLH (basic helix-loop-helix) domain
    Similarity: Contains 1 PAS (PER-ARNT-SIM) domain


    Find genes that share domains with NCOA2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NCOA2_HUMAN, Q15596
    Function: Transcriptional coactivator for steroid receptors and nuclear receptors. Coactivator of the steroid
    binding domain (AF-2) but not of the modulating N-terminal domain (AF-1). Required with NCOA1 to control energy
    balance between white and brown adipose tissues

         Enzyme Number (IUBMB): EC 2.3.1.482

         Gene Ontology (GO): Selected molecular function terms (see all 12):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding ----
    GO:0003682chromatin binding IEA--
    GO:0003713transcription coactivator activity NAS9430642
    GO:0004402histone acetyltransferase activity IEA--
    GO:0004871signal transducer activity IEA--
         
    Find genes that share ontologies with NCOA2           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for NCOA2:
     Increased viability after born 

         8 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Ncoa2):
     behavior/neurological  embryogenesis  endocrine/exocrine gland  growth/size/body  immune system 
     integument  no phenotypic analysis  reproductive system 

    Find genes that share phenotypes with NCOA2           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Ncoa2tm1.2Ipc for NCOA2

       genOway: Develop your customized and physiologically relevant rodent model for NCOA2

    miRNA
    Products:
        
    miRTarBase miRNAs that target NCOA2:
    hsa-mir-137 (MIRT004004), hsa-mir-193b-3p (MIRT041215)

    Block miRNA regulation of human, mouse, rat NCOA2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NCOA2 (see all 38):
    hsa-miR-429 hsa-miR-875-5p hsa-miR-218-1* hsa-miR-374c hsa-miR-3658 hsa-miR-4325 hsa-miR-186 hsa-miR-155*
    SwitchGear 3'UTR luciferase reporter plasmidNCOA2 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for NCOA2
    Predesigned siRNA for gene silencing in human, mouse, rat NCOA2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for NCOA2

    Clone
    Products:
         
    OriGene clones in human, mouse for NCOA2 (see all 8)
    OriGene ORF clones in mouse, rat for NCOA2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NCOA2 (NM_006540)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NCOA2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NCOA2

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for NCOA2
    Browse ESI BIO Cell Lines and PureStem Progenitors for NCOA2 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NCOA2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    NCOA2_HUMAN, Q15596: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2
    peroxisome1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ----
    GO:0005654nucleoplasm TAS--
    GO:0005737cytoplasm IEA--

    Find genes that share ontologies with NCOA2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for NCOA2 About   (see all 27)  
    See pathways by source

    SuperPathContained pathways About
    1Fatty acid, triacylglycerol, and ketone body metabolism
    Fatty acid, triacylglycerol, and ketone body metabolism0.65
    PPARA Activates Gene Expression0.63
    Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)0.65
    Transcriptional Regulation of White Adipocyte Differentiation0.38
    2Circadian Repression of Expression by REV-ERBA
    Circadian Repression of Expression by REV-ERBA0.88
    YAP1- and WWTR1 (TAZ)-stimulated gene expression0.40
    RORA Activates Circadian Expression0.88
    3Regulation of Cholesterol Biosynthesis by SREBP (SREBF)
    Regulation of Cholesterol Biosynthesis by SREBP (SREBF)0.75
    Activation of Gene Expression by SREBP (SREBF)0.75
    4Circadian Clock
    Circadian Clock0.66
    BMAL1-CLOCK/NPAS2 Activates Circadian Expression0.66
    5Gene Expression
    Generic Transcription Pathway0.40
    Gene Expression0.40


    Find genes that share SuperPaths with NCOA2           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    3 Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for NCOA2
        AHR Pathway
    Androgen Signaling
    Estrogen Pathway

    Selected GeneGo (Thomson Reuters) Pathways for NCOA2 (see all 7)
        Transcription Androgen Receptor nuclear signaling
    Development Ligand-independent activation of ESR1 and ESR2
    Development Role of HDAC and calcium/calmodulin-dependent kinase (CaMK) in control of skeletal myogenesis
    Transcription Ligand-Dependent Transcription of Retinoid-Target genes
    Development Ligand-dependent activation of the ESR1/AP-1 pathway

    Selected BioSystems Pathways for NCOA2 (see all 10)
        Adipogenesis
    Androgen receptor signaling pathway
    Corticotropin-releasing hormone
    Regulation of nuclear SMAD2/3 signaling
    Glucocorticoid receptor regulatory network

    Selected Reactome Pathways for NCOA2 (see all 10)
        Transcriptional regulation of white adipocyte differentiation
    Circadian Clock
    Transcriptional activation of mitochondrial biogenesis
    YAP1- and WWTR1 (TAZ)-stimulated gene expression
    Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)


    1 Kegg Pathway  (Kegg details for NCOA2):
        Thyroid hormone signaling pathway

        Pathway & Disease-focused RT2 Profiler PCR Arrays including NCOA2: 
              Estrogen Receptor Signaling in human mouse rat
              Nuclear Receptors & Coregulators in human mouse rat
              Adipogenesis in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for NCOA2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for NCOA2 (Q155961, 2, 3 ENSP000003999684) via UniProtKB, MINT, STRING, and/or I2D (see all 220)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ARP102751, 2, 3, ENSP000003638224EBI-81236,EBI-608057 MINT-49804 I2D: score=6 STRING: ENSP00000363822
    PSMB9P280653, ENSP000003639934I2D: score=1 STRING: ENSP00000363993
    ENSG00000239836P280653I2D: score=1 
    ENSG00000240118P280653I2D: score=1 
    ENSG00000240508P280653I2D: score=1 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter IEA--
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated NAS8670870
    GO:0007165signal transduction ----
    GO:0030521androgen receptor signaling pathway RCA19641626

    Find genes that share ontologies with NCOA2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NCOA2

    Selected DrugBank Compounds for NCOA2 (see all 23)    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    (2E,4E)-11-METHOXY-3,7,11-TRIMETHYLDODECA-2,4-DIENOIC ACID-- --target--10592235
    (9ALPHA,13BETA,17BETA)-2-[(1Z)-BUT-1-EN-1-YL]ESTRA-1,3,5(10)-TRIENE-3,17-DIOL-- --target--10592235
    (9BETA,11ALPHA,13ALPHA,14BETA,17ALPHA)-11-(METHOXYMETHYL)ESTRA-1(10),2,4-TRIENE-3,17-DIOL-- --target--10592235
    17-METHYL-17-ALPHA-DIHYDROEQUILENIN-- --target--10592235
    2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE-- --target--10592235
    2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID-- --target--10592235
    2-chloro-5-nitro-N-phenylbenzamide-- --target--10592235
    3-CHLORO-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL-- --target--10592235
    3-ETHYL-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL-- --target--10592235
    4-(2-amino-1-methyl-1H-imidazo[4,5-b]pyridin-6-yl)phenol-- --target--10592235

    Selected Novoseek inferred chemical compound relationships for NCOA2 gene (see all 31)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    steroid 73.5 98 9111344 (5), 11923473 (2), 9482670 (2), 9238002 (2) (see all 53)
    estrogen 70.3 43 11250900 (3), 19198856 (3), 18521745 (3), 18499756 (2) (see all 23)
    testosterone 66.7 56 12588987 (5), 9482670 (2), 17364555 (2), 9920895 (1) (see all 24)
    bicalutamide 60.1 17 19240160 (3), 12376534 (1), 17079484 (1)
    androstane 58.9 2 15591315 (1), 15557560 (1)
    4-hydroxytamoxifen 57.2 2 10966511 (1), 9875847 (1)
    retinoid 53.8 12 12205093 (1), 15137909 (1), 9111344 (1), 15731352 (1) (see all 8)
    vitamin d 48.3 10 9111344 (2), 9891040 (1), 10825392 (1), 19255064 (1) (see all 6)
    retinoic acid 45.9 15 17389641 (2), 15234273 (2), 10598588 (1), 9920895 (1) (see all 9)
    tamoxifen 44.6 6 10986290 (2), 15060164 (1), 12684393 (1), 12839940 (1) (see all 5)



    Find genes that share compounds with NCOA2           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for NCOA2 gene: 
    NM_006540.2  

    Unigene Cluster for NCOA2:

    Nuclear receptor coactivator 2
    Hs.446678  [show with all ESTs]
    Unigene Representative Sequence: NM_006540
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000452400(uc011lfb.1 uc003xyn.1) ENST00000518287 ENST00000518363
    ENST00000521239 ENST00000522054 ENST00000524223 ENST00000519724 ENST00000520416
    ENST00000267974
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat NCOA2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NCOA2 (see all 38):
    hsa-miR-429 hsa-miR-875-5p hsa-miR-218-1* hsa-miR-374c hsa-miR-3658 hsa-miR-4325 hsa-miR-186 hsa-miR-155*
    SwitchGear 3'UTR luciferase reporter plasmidNCOA2 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for NCOA2
    Predesigned siRNA for gene silencing in human, mouse, rat NCOA2
    Clone
    Products:
         
    OriGene clones in human, mouse for NCOA2 (see all 8)
    OriGene ORF clones in mouse, rat for NCOA2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NCOA2 (NM_006540)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NCOA2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NCOA2
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for NCOA2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NCOA2
      QuantiTect SYBR Green Assays in human, mouse, rat NCOA2
      QuantiFast Probe-based Assays in human, mouse, rat NCOA2

    Additional mRNA sequence: 

    AK021838.1 AK298528.1 AK308426.1 BC114383.1 EF374064.1 X97674.1 

    6 DOTS entries:

    DT.444147  DT.70103935  DT.91912103  DT.97773128  DT.101960748  DT.86844966 

    Selected AceView cDNA sequences (see all 170):

    CB151315 AA338057 BM728417 BI963844 AI652063 BU632095 CB156018 AA972014 
    AA382803 AW241303 AI890157 AA557462 CB242420 BG034089 AA292969 AA455270 
    BM459228 AA382443 CK903771 R08880 AA382440 BQ024776 AL042565 AL703633 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for NCOA2 (see all 6)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15 ^ 16a · 16b ^ 17a · 17b ^ 18a · 18b ^ 19a · 19b ^
    SP1:        -           -                                                                                                           -                           
    SP2:                                                                                                        -                       -                           
    SP3:                                                                                                                                                            
    SP4:                    -                                                                                                                                       
    SP5:                                                                                                                                                            

    ExUns: 20 ^ 21a · 21b ^ 22 ^ 23 ^ 24 ^ 25
    SP1:              -                           
    SP2:                                          
    SP3:                                          
    SP4:                                          
    SP5:                                          


    ECgene alternative splicing isoforms for NCOA2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    NCOA2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTACTAAGCA
    NCOA2 Expression
    About this image


    NCOA2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Thymus (Hematopoietic System)
             T Helper Cells Thymus
     
     Blood (Cardiovascular System)
             T Helper Cells Thymus
    NCOA2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NCOA2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.446678
        Pathway & Disease-focused RT2 Profiler PCR Arrays including NCOA2: 
              Estrogen Receptor Signaling in human mouse rat
              Nuclear Receptors & Coregulators in human mouse rat
              Adipogenesis in human mouse rat

    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for NCOA2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NCOA2
    QuantiTect SYBR Green Assays in human, mouse, rat NCOA2
    QuantiFast Probe-based Assays in human, mouse, rat NCOA2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NCOA2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for NCOA2 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ncoa21 , 5 nuclear receptor coactivator 21, 5 90.13(n)1
    94.19(a)1
      1 (4.12 cM)5
    179781  NM_008678.21  NP_032704.21 
     131391055 
    chicken
    (Gallus gallus)
    Aves NCOA21 nuclear receptor coactivator 2 83.62(n)
    87.19(a)
      420176  XM_001231577.3  XP_001231578.2 
    lizard
    (Anolis carolinensis)
    Reptilia NCOA26
    nuclear receptor coactivator 2
    86(a)
    1 ↔ 1
    4(32160745-32307519)
    African clawed frog
    (Xenopus laevis)
    Amphibia ncoa2-A2 nuclear receptor coactivator 2 78.11(n)    AJ243119.1 
    zebrafish
    (Danio rerio)
    Actinopterygii tif22 transcriptional intermediary factor 2 74.91(n)   81884  AF323989.1 


    ENSEMBL Gene Tree for NCOA2 (if available)
    TreeFam Gene Tree for NCOA2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for NCOA2 gene
    NCOA32  NCOA12  
    5 SIMAP similar genes for NCOA2 using alignment to 6 protein entries:     NCOA2_HUMAN (see all proteins):
    MYST3/NCOA2 fusion    NCOA3    CLOCK    NPAS2    NCOA1

    Find genes that share paralogs with NCOA2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for NCOA2 (see all 5479)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs32154301,2
    C--66532109(-) GTCTT-/ACTT  
            
    TAAGA
    1 -- int10--------
    rs715604041,2
    C--66803006(+) AAAGG-/A/AAA 
            
    AAAAA
    1 -- int11NA 2
    rs29547281,2
    C,H--71023866(+) TGCAAA/CTTTCC 1 -- ds50016Minor allele frequency- C:0.00NS EA NA 378
    rs1481246701,2
    --71023881(+) AGGTTC/TTTTAG 1 -- ds50010--------
    rs1830727171,2
    --71023956(+) TTCCAC/TAATGC 1 -- ds50010--------
    rs1439903231,2
    --71023961(+) TAATGC/TGTACA 1 -- ds50010--------
    rs1864473391,2
    --71023998(+) GGGGTA/TGTTTG 1 -- ds50010--------
    rs1916815761,2
    --71024021(+) CCTGCC/GACAAA 1 -- ds50010--------
    rs37502001,2
    C,F,H--71024034(+) AACAAA/TCAATC 1 -- ds50015Minor allele frequency- T:0.01EA NS 1168
    rs1829971021,2
    --71024063(+) TCTCTG/TTTCCT 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for NCOA2 (71021997 - 71271997 bp, first 250kb of NCOA2)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for NCOA2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2737143CNV Deletion23290073
    nsv6246CNV Insertion18451855
    nsv6248CNV Loss18451855
    nsv6247CNV Loss18451855
    nsv397839CNV Loss16902084
    nsv508513CNV Loss20534489
    dgv7805n71CNV Gain21882294
    nsv831352CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    1 Copy Number PCR Panel containing NCOA2:
    Prostate Cancer
    SeqTarget long-range PCR primers for resequencing NCOA2
    DNA2.0 Custom Variant and Variant Library Synthesis for NCOA2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 601993    OMIM disorders: --

    UniProtKB/Swiss-Prot: NCOA2_HUMAN, Q15596
  • Note=Chromosomal aberrations involving NCOA2 may be a cause of acute myeloid leukemias. Inversion
    inv(8)(p11;q13) generates the KAT6A-NCOA2 oncogene, which consists of the N-terminal part of KAT6A and the
    C-terminal part of NCOA2/TIF2. KAT6A-NCOA2 binds to CREBBP and disrupts its function in transcription activation

  • 4 diseases for NCOA2:    
    About MalaCards
    spindle cell rhabdomyosarcoma    partial androgen insensitivity syndrome    mesenchymal chondrosarcoma    prostate cancer

    2 diseases from the University of Copenhagen DISEASES database for NCOA2:
    Mesenchymal chondrosarcoma     Wolf-Hirschhorn syndrome

    Find genes that share disorders with NCOA2           About GenesLikeMe

    Selected Novoseek inferred disease relationships for NCOA2 gene (see all 16)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    prostate cancer 45.8 15 19240160 (2), 17079484 (2), 14871982 (1), 11489729 (1) (see all 6)
    recurrent prostate cancer 42.3 1 11389051 (1)
    mammary tumor 38.7 3 15459252 (1), 9717843 (1), 17635946 (1)
    breast cancer 37.4 19 18521745 (2), 10690532 (1), 19183483 (1), 10598585 (1) (see all 13)
    leukemogenesis 34.9 1 12619166 (1)
    monocytic leukemia 34.6 2 9731070 (1)
    leukaemia lymphocytic 5.49 1 9705873 (1)
    cancer 1.61 2 9705873 (1), 17079484 (1)
    leukemia 0 5 18281529 (1), 17697320 (1), 9731070 (1)
    necrosis 0 2 11489729 (2)

    Genetic Association Database (GAD): NCOA2
    Human Genome Epidemiology (HuGE) Navigator: NCOA2 (12 documents)

    Export disorders for NCOA2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for NCOA2 gene, integrated from 10 sources (see all 368):
    (articles sorted by number of sources associating them with NCOA2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors. (PubMed id 8670870)1, 2, 3, 9 Voegel J.J.... Gronemeyer H. (EMBO J. 1996)
    2. GRIP1, a transcriptional coactivator for the AF-2 transactivation domain of steroid, thyroid, retinoid, and vitamin D receptors. (PubMed id 9111344)1, 3, 9 Hong H....Stallcup M.R. (Mol. Cell. Biol. 1997)
    3. A subfamily of RNA-binding DEAD-box proteins acts as an estrogen receptor alpha coactivator through the N-terminal activation domain (AF-1) with an RNA coactivator, SRA. (PubMed id 11250900)1, 2, 9 Watanabe M....Kato S. (EMBO J. 2001)
    4. Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort. (PubMed id 19183483)1, 4, 9 Haiman C.A....Press M.F. (BMC Cancer 2009)
    5. Vitamin D-related genes, serum vitamin D concentrations and prostate cancer risk. (PubMed id 19255064)1, 4, 9 Ahn J....Hayes R.B. (Carcinogenesis 2009)
    6. Redox-regulated recruitment of the transcriptional coactivators CREB- binding protein and SRC-1 to hypoxia-inducible factor 1alpha. (PubMed id 10594042)1, 2, 9 Carrero P....Poellinger L. (Mol. Cell. Biol. 2000)
    7. A novel fusion between MOZ and the nuclear receptor coactivator TIF2 in acute myeloid leukemia. (PubMed id 9558366)1, 2, 9 Carapeti M.... Cross N.C.P. (Blood 1998)
    8. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    9. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    10. High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. (PubMed id 19453261)1, 4 Yerges L.M....Zmuda J.M. (J. Bone Miner. Res. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 10499 HGNC: 7669 AceView: NCOA2 Ensembl:ENSG00000140396 euGenes: HUgn10499
    ECgene: NCOA2 Kegg: 10499 H-InvDB: NCOA2

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for NCOA2 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for NCOA2 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for NCOA2 gene:
    Search GeneIP for patents involving NCOA2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
    About This Section

    TryGeneCards Plus

     Browse Purified and Recombinant Proteins at EMD Millipore
     EMD Millipore Mono- and Polyclonal Antibodies for the study of NCOA2
     Browse Small Molecules at EMD Millipore
     Browse Kits and Assays available from EMD Millipore
     
     EMD Millipore genomic analysis products

      
     Antibodies for NCOA2 (NCOA2)   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for NCOA2   OriGene RNAi products in human, mouse, rat for NCOA2  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for NCOA2  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for NCOA2  
     OriGene qSTAR qPCR primer pairs in human, mouse for NCOA2   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for NCOA2   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for NCOA2   OriGene Custom Protein Services for NCOA2  

     
     
     Block miRNA regulation of human, mouse, rat NCOA2 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing NCOA2
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NCOA2 Predesigned siRNA for gene silencing in human, mouse, rat NCOA2
     QuantiFast Probe-based Assays in human, mouse, rat NCOA2 QuantiTect SYBR Green Assays in human, mouse, rat NCOA2
     PCR Arrays including human, mouse, rat NCOA2 Search Chromatin IP Primers for NCOA2
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NCOA2  GeneGlobe Interaction Network for NCOA2
     Regulatory tfbs in NCOA2 promoter
     GenScript Custom Purified and Recombinant Proteins Services for NCOA2 GenScript cDNA clones with any tag delivered in your preferred vector for NCOA2
     GenScript Custom Assay Services for NCOA2 GenScript Custom overexpressing Cell Line Services for NCOA2
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for NCOA2
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     NCOA2 antibodies
     NCOA2 proteins
     NCOA2 lysates
     Antibodies for NCOA2
     See all of Abcam's Antibodies, Kits and Proteins for NCOA2
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for NCOA2
     Antibodies for NCOA2
     ELISAs for NCOA2
     CLIAs for NCOA2



     Browse ESI BIO Cell Lines and PureStem Progenitors for NCOA2
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NCOA2
     SwitchGear 3'UTR luciferase reporter plasmids for NCOA2
     Browse SwitchGear Promoter luciferase reporter plasmids for NCOA2
     ThermoFisher Antibodies for NCOA2
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NCOA2
     Browse compounds at ApexBio
     Search Addgene for plasmids for NCOA2
      Search eBioscience for proteins for NCOA2
      Search eBioscience for elisas for NCOA2
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for NCOA2
     antibodies-online antibodies for NCOA2 (52 products)
     antibodies-online kits for NCOA2 (6 products)
     antibodies-online peptides for NCOA2
     antibodies-online proteins for NCOA2 (2 products)
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      NCOA2 gene at Home site.
    Version: 3.12.250 16 Nov 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4