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Aliases for NCMAP Gene

Aliases for NCMAP Gene

  • Non-Compact Myelin Associated Protein 2 3 5
  • Myelin Protein Of 11 KDa 2 3 4
  • C1orf130 3 4
  • MP11 3 4
  • Noncompact Myelin-Associated Protein 3
  • Chromosome 1 Open Reading Frame 130 2

External Ids for NCMAP Gene

Previous HGNC Symbols for NCMAP Gene

  • C1orf130

Previous GeneCards Identifiers for NCMAP Gene

  • GC01P024883

Summaries for NCMAP Gene

GeneCards Summary for NCMAP Gene

NCMAP (Non-Compact Myelin Associated Protein) is a Protein Coding gene. GO annotations related to this gene include structural constituent of myelin sheath.

UniProtKB/Swiss-Prot for NCMAP Gene

  • Plays a role in myelin formation.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NCMAP Gene

Genomics for NCMAP Gene

Regulatory Elements for NCMAP Gene

Enhancers for NCMAP Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G024641 1.5 FANTOM5 ENCODE 15.3 +87.3 87328 4.1 MLX CREB3L1 AGO1 DMAP1 YY1 ZNF143 ZNF263 MCM3 SP3 NFYC NCMAP SYF2 RPL11 PNRC2 ENSG00000261349 ELOA RUNX3 SRRM1 GC01P024703
GH01G024555 1.1 ENCODE dbSUPER 20.3 +0.8 847 3.5 ELF3 ATF1 MLX ZSCAN4 ARID4B RAD21 RARA CREM SP5 MXD4 NCMAP RCAN3 LOC100506985 RPL26P8
GH01G024414 1.7 Ensembl ENCODE dbSUPER 10.2 -138.8 -138806 5.3 DMAP1 FEZF1 YY1 ZNF143 ZNF263 SP3 NFYC TBX21 MEF2D ZNF610 ELOA STPG1 ENSG00000261349 NIPAL3 RCAN3 SYF2 NCMAP GC01P024477
GH01G024768 1.7 FANTOM5 Ensembl ENCODE dbSUPER 9.7 +214.1 214059 4.0 HDAC1 CBX3 FEZF1 ZBTB40 ZNF121 ELK1 ZNF366 ZSCAN5C FOS SMARCA5 NCMAP CLIC4 RNU6-1208P GC01M024778
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around NCMAP on UCSC Golden Path with GeneCards custom track

Promoters for NCMAP Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000003215 24 201 CTCF SAP130 SP5 GABPB1 RAD21 RBFOX2 EZH2

Genomic Location for NCMAP Gene

24,556,076 bp from pter
24,609,328 bp from pter
53,253 bases
Plus strand

Genomic View for NCMAP Gene

Genes around NCMAP on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NCMAP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NCMAP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NCMAP Gene

Proteins for NCMAP Gene

  • Protein details for NCMAP Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Noncompact myelin-associated protein
    Protein Accession:
    Secondary Accessions:
    • A0PK04
    • B2RV34

    Protein attributes for NCMAP Gene

    102 amino acids
    Molecular mass:
    11082 Da
    Quaternary structure:
    No Data Available

neXtProt entry for NCMAP Gene

Post-translational modifications for NCMAP Gene

Other Protein References for NCMAP Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for NCMAP Gene

Domains & Families for NCMAP Gene

Protein Domains for NCMAP Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with NCMAP: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for NCMAP Gene

Function for NCMAP Gene

Molecular function for NCMAP Gene

UniProtKB/Swiss-Prot Function:
Plays a role in myelin formation.

Gene Ontology (GO) - Molecular Function for NCMAP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0019911 structural constituent of myelin sheath ISS --
genes like me logo Genes that share ontologies with NCMAP: view
genes like me logo Genes that share phenotypes with NCMAP: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for NCMAP Gene

Localization for NCMAP Gene

Subcellular locations from UniProtKB/Swiss-Prot for NCMAP Gene

Cell membrane; Single-pass type I membrane protein. Note=Localized mainly in the Schmidt-Lanterman incisures and paranodes of noncompact peripheral nerve myelin. {ECO:0000250}.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for NCMAP gene
Compartment Confidence
plasma membrane 5
cytosol 2
extracellular 1
peroxisome 1
nucleus 1

Gene Ontology (GO) - Cellular Components for NCMAP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005887 integral component of plasma membrane ISS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
GO:0033270 paranode region of axon ISS --
GO:0043220 Schmidt-Lanterman incisure ISS --
genes like me logo Genes that share ontologies with NCMAP: view

Pathways & Interactions for NCMAP Gene

SuperPathways for NCMAP Gene

No Data Available

Interacting Proteins for NCMAP Gene

Gene Ontology (GO) - Biological Process for NCMAP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0031643 positive regulation of myelination ISS --
GO:0032290 peripheral nervous system myelin formation ISS --
genes like me logo Genes that share ontologies with NCMAP: view

No data available for Pathways by source and SIGNOR curated interactions for NCMAP Gene

Drugs & Compounds for NCMAP Gene

No Compound Related Data Available

Transcripts for NCMAP Gene

mRNA/cDNA for NCMAP Gene

(3) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(20) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for NCMAP Gene

Noncompact myelin associated protein:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for NCMAP Gene

ExUns: 1 ^ 2a · 2b ^ 3a · 3b · 3c
SP1: -
SP2: -

Relevant External Links for NCMAP Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for NCMAP Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for NCMAP Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for NCMAP Gene

This gene is overexpressed in Nerve - Tibial (x31.1) and Pancreas (x4.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for NCMAP Gene

NURSA nuclear receptor signaling pathways regulating expression of NCMAP Gene:


SOURCE GeneReport for Unigene cluster for NCMAP Gene:


Evidence on tissue expression from TISSUES for NCMAP Gene

  • Nervous system(4)
genes like me logo Genes that share expression patterns with NCMAP: view

Primer Products

No data available for Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for NCMAP Gene

Orthologs for NCMAP Gene

This gene was present in the common ancestor of mammals.

Orthologs for NCMAP Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia NCMAP 34 35
  • 99.35 (n)
(Canis familiaris)
Mammalia NCMAP 34 35
  • 89.77 (n)
(Bos Taurus)
Mammalia NCMAP 34 35
  • 88.24 (n)
(Mus musculus)
Mammalia Ncmap 34 16 35
  • 84.67 (n)
(Rattus norvegicus)
Mammalia Ncmap 34
  • 84 (n)
(Monodelphis domestica)
Mammalia NCMAP 35
  • 63 (a)
(Ornithorhynchus anatinus)
Mammalia NCMAP 35
  • 57 (a)
Species where no ortholog for NCMAP was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for NCMAP Gene

Gene Tree for NCMAP (if available)
Gene Tree for NCMAP (if available)

Paralogs for NCMAP Gene

No data available for Paralogs for NCMAP Gene

Variants for NCMAP Gene

Sequence variations from dbSNP and Humsavar for NCMAP Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000044625 -- 24,594,652(+) TTTCA(A/G)GGCAT intron-variant
rs1000095640 -- 24,554,475(+) AACCT(A/G)AGACC intron-variant, upstream-variant-2KB
rs1000216218 -- 24,561,933(+) AAAAG(A/G)AGGGA intron-variant
rs1000222120 -- 24,557,395(+) TGTGC(-/AT)GTGTG intron-variant, upstream-variant-2KB
rs1000222964 -- 24,571,822(+) CTCAA(A/G)TGATC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for NCMAP Gene

Variant ID Type Subtype PubMed ID
dgv31e199 CNV deletion 23128226
esv1961948 CNV deletion 18987734
esv2665308 CNV deletion 23128226
esv27046 CNV loss 19812545
esv3585506 CNV loss 21293372
nsv1140258 OTHER inversion 24896259
nsv1147629 CNV deletion 26484159
nsv436645 CNV deletion 17901297
nsv545823 CNV gain 21841781
nsv834458 CNV loss 17160897

Variation tolerance for NCMAP Gene

Residual Variation Intolerance Score: 79.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.16; 51.72% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for NCMAP Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NCMAP Gene

Disorders for NCMAP Gene

Relevant External Links for NCMAP

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for NCMAP Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NCMAP Gene

Publications for NCMAP Gene

  1. Analysis of peripheral nerve expression profiles identifies a novel myelin glycoprotein, MP11. (PMID: 18650334) Ryu E.J. … Milbrandt J. (J. Neurosci. 2008) 2 3 64
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for NCMAP Gene

Sources for NCMAP Gene

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