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NCKIPSD Gene

protein-coding   GIFtS: 50

GC03M048675
NCK interacting protein with SH3 domain
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
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Aliases &
Descriptions
for NCKIPSD gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
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Aliases & Descriptions
NCK interacting protein with SH3 domain1 2     DIP-12 3
AF3P211 2 3 5     54 kDa VacA-interacting protein2 3
SPIN901 2 3 5     SH3 adapter protein SPIN902 3
WISH1 2     NCK-interacting protein with SH3 domain2
DIP11 2     DIP2
ORF11 2     diaphanous protein interacting protein2
WASLBP1 2     MGC238912
Dia-interacting protein 12 3     SH3 protein interacting with Nck, 90 kDa2
Diaphanous protein-interacting protein2 3     dia interacting protein2
VIP542 3     AF3p213
90 kDa SH3 protein interacting with Nck2 3     

External Ids:    HGNC: 154861   Entrez Gene: 515172   Ensembl: ENSG000002136727   UniProtKB: Q9NZQ33   

Search outside databases for aliases for NCKIPSD gene

Previous GC identifer: GC03M048661

Summaries
for NCKIPSD gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

  User Feedback		 Entrez Gene summary for NCKIPSD:
The protein encoded by this gene is localized exclusively in the cell nucleus. It plays a role in signal transduction,
and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an
important role in stress fiber formation. The gene is involved in therapy-related leukemia by a chromosomal
translocation t(3;11)(p21;q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing
occurs in this locus and two transcript variants encoding distinct isoforms have been identified. (provided by RefSeq)

UniProtKB/Swiss-Prot: SPN90_HUMAN, Q9NZQ3
Function: Has an important role in stress fiber formation induced by active diaphanous protein homolog 1 (DRF1).
Induces microspike formation, in vivo (By similarity). In vitro, stimulates N-WASP-induced ARP2/3 complex activation
in the absence of CDC42 (By similarity). May play an important role in the maintenance of sarcomeres and/or in the
assembly of myofibrils into sarcomeres. Implicated in regulation of actin polymerization and cell adhesion

Gene Wiki entry for NCKIPSD

Genomic Views
for NCKIPSD gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC and Ensembl (release 56), Regulatory elements and Epigenetics data according to SABiosciences)
About This Section

  User Feedback		 Regulatory elements:
"" SABiosciences Regulatory transcription factor binding sites in the NCKIPSD gene upstream (promoter) region "":
AP-1   c-Fos   c-Jun   Pax-2   Meis-1   HOXA9B   Pax-6   ZID   GR-beta   GR-alpha   

Epigenetics:
"" SABiosciences Methyl-Profiler DNA Methylation qPCR Primer Assays for NCKIPSD:  ""
MePH04901-1A   

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p21   Ensembl cytogenetic band:  3p21.31   HGNC cytogenetic band: 3p21

NCKIPSD Gene in genomic location: bands according to Ensembl, locations according to "" (and/or Entrez Gene and/or Ensembl if different)
""

GeneLoc gene densities for chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M048675:  view genomic region     (about GC identifiers)

Start:
 48,701,364 bp from pter
End:
 48,723,797 bp from pter
Size:
 22,434 bases
Orientation:
 minus strand
RefSeq DNA sequence:
NC_000003.11  NT_022517.18  

Proteins
for NCKIPSD gene

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene, Novus Biologicals, and/or Sino Biological,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 May 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abnova, OriGene, Novus Biologicals, and/or Epitomics)
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  User Feedback		 UniProtKB/Swiss-Prot: SPN90_HUMAN, Q9NZQ3 (See protein sequence)
Recommended Name: NCK-interacting protein with SH3 domain  
Size: 722 amino acids; 78960 Da
Subunit: Associates with the intermediate filaments, vimentin and desmin. Binds the first and third SH3 domains of NCK.
Binds the proline-rich domains of N-WASP through its SH3 domain (By similarity). Similarly, binds diaphanous protein
homolog 1 (DRF1). Binds the SH3 domains of GRB2 through its proline-rich domains
Subcellular location: Nucleus. Note=Colocalizes with DRF1 at membrane ruffles, and with Nck at Z-disks in mature
cardiac myocytes
Secondary accessions: Q9UGM8
Alternative splicing: 2 isoforms:  Q9NZQ3-1   Q9NZQ3-2   

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


    • REFSEQ proteins (2 alternative transcripts): 
    NP_057537.1  NP_909119.1  


    ENSEMBL proteins: 
    ENSP00000342621 ENSP00000416904 ENSP00000408588 ENSP00000416144 ENSP00000406442 ENSP00000396683 
    ENSP00000409675 ENSP00000294129 ENSP00000389059 


    Human Recombinant Proteins 
    ""Browse Purified and Recombinant Proteins at Millipore
    ""Browse Human Recombinant Proteins at Sigma-Aldrich
    "" Browse R&D Systems for human recombinant proteins
    ""Browse recombinant and purified proteins available from Enzo Life Sciences
    ""HuPro® and/or Recombinant Proteins from Abnova for NCKIPSD ""
    ""Browse Origene full length recombinant human proteins expressed in human HEK293 cells
    ""Novus Biologicals Proteins for NCKIPSD  ""
    Novus Biologicals Lysate for NCKIPSD
    ""Browse Sino Biological Recombinant Proteins  ""

    2 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634 nucleus IEA--
    GO:0005882 intermediate filament NAS10619843
    About this table

    "" NCKIPSD for ontologies           About GeneDecksing



    Antibodies for NCKIPSD: 
    ""Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    ""Sigma-Aldrich Antibodies for NCKIPSD
    "" Browse R&D Systems for Antibodies
    ""Monoclonal and Polyclonal Antibodies from Abnova (NCKIPSD)
    ""Browse Origene Antibodies ""
    ""Novus Biologicals Antibodies for NCKIPSD
    ""Browse antibodies at Epitomics

    Assays for NCKIPSD: 
    ""Browse Kits and Assays available from Millipore
    ""Browse ELISAs at Sigma-Aldrich
    "" Browse R&D Systems for biochemical assays
    ""Browse Enzo Life Sciences for kits & assays

    Protein Domains/
    Families
    for NCKIPSD gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

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    "" NCKIPSD for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR018556 DUF2013
     IPR001452 SH3_domain

    Graphical View of Domain Structure for InterPro Entry Q9NZQ3

    ProtoNet protein and cluster: Q9NZQ3

    1 Blocks protein family: IPB001452 SH3 domain signature

    UniProtKB/Swiss-Prot: SPN90_HUMAN, Q9NZQ3
    Similarity: Contains 1 SH3 domain

    Gene Function
    for NCKIPSD gene

    (According to MGI May 08 2010, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, Abnova, siRNAs from Applied Biosystems, Sigma-Aldrich, Clones from Millipore, Sigma-Aldrich, OriGene, Sino Biological, Ontologies according to Gene Ontology Consortium 01 May 2010 via Entrez Gene.)
    About This Section

      User Feedback
    Inhib.
    RNA:    		""Browse for Gene Knock-down Tools from Millipore
    ""Browse Abnova for Chimera RNAi Products
    "" Origene 29mer shRNA kits in GFP-retroviral vector (see all 2): NCKIPSD
    Origene shRNA RFP (see all 2): NCKIPSD
    Origene basic RS shRNA (see all 2): NCKIPSD

    ""Applied Biosystems Silencer® siRNAs for NCKIPSD
    ""Sigma-Aldrich siRNA for NCKIPSD
    Sigma-Aldrich shRNA for NCKIPSD
    Explore Sigma-Aldrich super-pooled esiRNAs
    Clones:""Browse Clones for the Expression of Recombinant Proteins Available from Millipore
    ""Browse iPSC Reprogramming Factors at Sigma-Aldrich
    "" Origene GFP tagged cDNA clones in CMV expression vector (see all 2): NCKIPSD
    Origene Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NCKIPSD
    Origene untagged cDNA clones in CMV expression vector (see all 2): NCKIPSD
    ""Browse Sino Biological Human cDNA Clones  ""

    UniProtKB/Swiss-Prot: SPN90_HUMAN, Q9NZQ3
    Function: Has an important role in stress fiber formation induced by active diaphanous protein homolog 1 (DRF1).
    Induces microspike formation, in vivo (By similarity). In vitro, stimulates N-WASP-induced ARP2/3 complex activation
    in the absence of CDC42 (By similarity). May play an important role in the maintenance of sarcomeres and/or in the
    assembly of myofibrils into sarcomeres. Implicated in regulation of actin polymerization and cell adhesion

    3 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515 protein binding IPI16253999 17474147 19807924
    GO:0008092 cytoskeletal protein binding NAS10619843
    GO:0017124 SH3 domain binding IEA--
    About this table

    "" NCKIPSD for ontologies           About GeneDecksing

    Animal Models: 5 MGI mutant phenotypes (inferred from 3 alleles"") (MGI details for Nckipsd):

    cellulargrowth/sizenervous systemno phenotypic analysisreproductive system

    "" NCKIPSD for phenotypes           About GeneDecksing

    Pathways & Interactions
    for NCKIPSD gene

    (Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, Applied Biosystems GeneAssist, KEGG and/or UniProtKB, (map by GeneGo),
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 May 2010 via Entrez Gene).
    About This Section

      User Feedback    		"" SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for NCKIPSD

    5/15 Interacting proteins for NCKIPSD (Q9NZQ31, 2) via UniProtKB, MINT, and/or STRING (see all 15 ) ""
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ABL1P005191, 2EBI-957585,EBI-375543 MINT-7244086 EBI-957585,EBI-375543 MINT-7244086
    FYNP062411, 2EBI-957585,EBI-515315 MINT-7247146 EBI-957585,EBI-515315 MINT-7247146
    FASLGP480231EBI-957585,EBI-495538
    BAIAP2Q9UQB82MINT-7219383
    RAC1P630002MINT-7219402
    About this table

    3 Gene Ontology (GO) biological process terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006607 NLS-bearing substrate import into nucleus TAS10648423
    GO:0007010 cytoskeleton organization NAS10619843
    GO:0007165 signal transduction TAS10648423
    About this table

    "" NCKIPSD for ontologies           About GeneDecksing


    Drugs & Compounds
    for NCKIPSD gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

      User Feedback
    "" NCKIPSD for compounds           About GeneDecksing

    "" Browse drugs & compounds from Enzo Life Sciences
    ""Browse Small Molecules at Sigma-Aldrich

    "" Browse Tocris compounds for NCKIPSD
    3 ""Novoseek chemical compound relationships for NCKIPSD gene
    Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    cytochalasin 2.40 1 14559906 (1)
    proline 1.01 1 17537434 (1)
    serine 0.63 1 14559906 (1)
    About this table


    Transcripts
    for NCKIPSD gene

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 223 Homo sapiens; Apr 2 2010) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Millipore and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene, microRNA from SABiosciences,
    Tagged/untagged cDNA clones from OriGene, Primers from OriGene and/or SABiosciences,
    Expression Assays from Applied Biosystems)
    About This Section

      User Feedback
    Inhib.
    RNA:    		""Browse for Gene Knock-down Tools from Millipore
    ""Browse Abnova for Chimera RNAi Products
    ""Applied Biosystems Silencer® siRNAs:  NM_016453  NM_184231  
    "" Origene 29mer shRNA kits in GFP-retroviral vector (see all 2): NCKIPSD
    Origene shRNA RFP (see all 2): NCKIPSD
    Origene basic RS shRNA (see all 2): NCKIPSD

    ""Sigma-Aldrich siRNA for NCKIPSD
    Sigma-Aldrich shRNA for NCKIPSD
    Explore Sigma-Aldrich super-pooled esiRNAs

    microRNA:""9 SABiosciences microRNAs that regulate NCKIPSD: ""
    hsa-miR-214 hsa-miR-124 hsa-miR-135b hsa-miR-133a hsa-miR-324-3p hsa-miR-326 hsa-miR-506 hsa-miR-133b hsa-miR-135a
    Assays:  ""Applied Biosystems TaqMan® Gene Expression Assays:  
    NM_016453  NM_184231  


    Clones:"" Origene GFP tagged cDNA clones in CMV expression vector (see all 2): NCKIPSD
    Origene Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NCKIPSD
    Origene untagged cDNA clones in CMV expression vector (see all 2): NCKIPSD
    Primers:"" Origene genome-wide validated SYBR primer pairs: NCKIPSD
    ""SABiosciences RT2 qPCR Primer Assay for NCKIPSD: PPH10887A ""

    REFSEQ mRNAs for NCKIPSD gene (2 alternative transcripts): 

    NM_016453.2  NM_184231.1  

    Additional cDNA sequence: 

    AF178432.1 AF303581.1 AJ242655.2 AK294151.1 AL049430.1 AY453794.1 BC006255.2 BC016052.1 
    BC026280.1 CR609217.1 CR624793.1 

    9 DOTS entries:

    DT.442329  DT.100781728  DT.305127  DT.40271098  DT.97846133  DT.100781726  DT.99950774  DT.95075914 
    DT.92430019 

    1 AceView cDNA sequence:

    BF894800 

    "" highest scoring ESTs for NCKIPSD:

    BC006255 BC016052 AA322751 AF178432 AF303581 AI245778 AI420887 AI827711 AJ242655 AL042685 

    Unigene Cluster for NCKIPSD:

    NCK interacting protein with SH3 domain
    Hs.655006  [show with all ESTs]
    Unigene Representative Sequence: AJ242655


    GeneLoc Exon Structure

    10 Ensembl transcripts including schematic representations:
    ENST00000341520  ENST00000426678  ENST00000453349  ENST00000454134  ENST00000415281  ENST00000413374  
    ENST00000439518  ENST00000470006  ENST00000294129  ENST00000416649  

    Expression
    for NCKIPSD gene

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 223 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems, Primers from OriGene and/or SABiosciences )
    About This Section

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    NCKIPSD expression in normal and diseased human tissues

    "" Applied Biosystems TaqMan ® Gene Expression Assays for NCKIPSD

    1""  / 2""  / 3""

    6 probe-sets matching NCKIPSD gene

    Affymetrix
    probe-set    		 Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    56174_at2, 3 U95-B 1 0.81 1.00 0.91 1.07 AL042685 0.60 1.00 0.82 1
    60710_at2, 3 U95-C 1 0.44 1.00 -0.03 0.93 AI245778 0.60 1.00 0.82 1
    218697_at2, 3 U133-A 1 1.00 1.00 -- -- NM_016453 0.60 1.00 0.82 1
    233165_at2, 3 U133-B 1 0.36 1.00 -- -- AJ242655 0.60 1.00 0.82 1
    218697_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    233165_at2 U133Plus2 1 0.36 1.00 -- -- -- -- -- -- --
    About this table

    "" NCKIPSD for expression           About GeneDecksing

    Data from Genenote  (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: TGTATTTTCC

    SOURCE GeneReport for Unigene cluster: Hs.655006

    Expression variation in blood from EXPOLDB for NCKIPSD

    UniProtKB/Swiss-Prot: SPN90_HUMAN, Q9NZQ3
    Tissue specificity: Highest expression in heart, brain, skeletal muscle, kidney and liver. Lower levels in placenta,
    lung, small intestine and leukocytes. Weak expression in colon, thymus and spleen

    Primers:"" Origene genome-wide validated SYBR primer pairs: NCKIPSD ""
    ""SABiosciences RT2 qPCR Primer Assay for NCKIPSD: PPH10887A ""

    Orthologs
    for NCKIPSD gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI May 08 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section

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    Orthologs for NCKIPSD gene from 5/7 species (see all 7 )
    Organism Gene Locus Description Human
    Similarity    		 NCBI accessions
    chimpanzee
    (Pan troglodytes)    		 NCKIPSD1   -- NCK interacting protein with SH3 domain 99.49(n)
    99.39(a)    		 460351  XM_516443.2  XP_516443.2 
    cow
    (Bos taurus)    		 NCKIPSD1   -- NCK interacting protein with SH3 domain 88.87(n)
    91.41(a)    		 516941  XM_001254499.1  XP_001254500.1 
    rat
    (Rattus norvegicus)    		 Nckipsd1   -- NCK interacting protein with SH3 domain 86.97(n)
    89.64(a)    		 301009  XM_238555.4  XP_238555.3 
    mouse
    (Mus musculus)    		 Nckipsd1, 5 95
    		 NCK interacting protein with SH3 domain1, 5 87.11(n)1
    89.36(a)1    		 809871  NM_030729.41  NP_109654.21 
     AF1303135  AK1347255  (see all 11)
    chicken
    (Gallus gallus)    		 NCKIPSD1   -- NCK interacting protein with SH3 domain 72.47(n)
    72.47(a)    		 770439  XM_001233773.1  XP_001233774.1 
    About this table        Species with no ortholog for NCKIPSD

    ENSEMBL Gene Tree for NCKIPSD

    Paralogs
    for NCKIPSD gene

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
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    Genomic Variants
    for NCKIPSD gene

    (SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Genotyping Reagents from Applied Biosystems)
    About This Section

      User Feedback
    10/72 NCBI SNPs in NCKIPSD are shown (see all 72 )
    (Click "" for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 34)
    ABGenomic DataTranscription Related DataAllele Frequencies
    SNP IDValidChr 3 posSequenceRecsAA
    Chg    		TypeMoreRecsAllele
    freq    		PopTotal
    sample    		More
    ------------
    ""
    rs67856201,2
    		C,F,H48718842(+) GCCAGT/AGTTTC 4 /T /S ref1 mis1""8Minor allele frequency- A:0.25NS EA 838""
    ""
    rs48588281,2
    		C,F,A48783232(+) AATCTT/CGGGGT 2 -- ng51""10Minor allele frequency- C:0.30NS EA NA WA 616""
    --
    rs67925101,2
    		C,A,H48723302(+) AGGCCC/GGGAGC 2 -- ut51""2Minor allele frequency- G:0.25NA 4""
    --
    rs126325331,2
    		C,A,H48783007(+) gtcctC/Tccagt 2 -- ng51""4Minor allele frequency- T:0.00NS EA 412""
    --
    rs178555161,2
    		H48712167(+) AGAGGT/GACTCC 4 /Y /S ref1 mis1""4Minor allele frequency- G:0.00NS EA 420""
    --
    rs353448671,2
    		C48782511(+) CCTTTC/TTGAGA 2 -- ng51""0--------
    ""
    rs360599091,2
    		C48716029(+) GTGCCG/ACACAG 4 /R /W ref1 mis1""1Minor allele frequency- A:0.01NA 78""
    --
    rs98297271,2
    		C48782246(+) AGAAGG/CGGGCC 2 -- ng51""1Minor allele frequency- C:0.02WA 50""
    --
    rs115457551,2
    		C48711659(-) GGCTGG/TACCAG 2 -- ut31""0--------
    ""
    rs130871681,2
    		C,F48717066(+) ACAAGC/TGTGGA 4 T syn1 ref1""6Minor allele frequency- T:0.00NS EA NA 424""
    About this table

    HapMap Linkage Disequilibrium images for NCKIPSD (up to first 250kb)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)  ""
    Database of Genomic Variants (DGV): 1 variation for NCKIPSD
         1 CNV: 9448

    Disorders & Mutations
    for NCKIPSD gene

    (in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

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    "" NCKIPSD for disorders           About GeneDecksing

    OMIM: 606671

    UniProtKB/Swiss-Prot: SPN90_HUMAN, Q9NZQ3
  • A chromosomal aberration involving NCKIPSD/AF3p21 is found in therapy-related leukemia. Translocation
    • t(3;11)(p21;q23) with MLL

    2 ""Novoseek disease relationships for NCKIPSD gene

    Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    leukemia 4.50 5 11697487 (2), 11241789 (2), 10648423 (1)
    leukemogenesis 1.74 1 11697487 (1)
    About this table

    Medical News
    for NCKIPSD gene

    (Possibly Related Articles in Doctor's Guide)
    About This Section

      User Feedback    		   --

    Publications
    for NCKIPSD gene

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

      User Feedback    		10/22 PubMed articles for NCKIPSD gene (see all 22 ):

    Search for NCKIPSD gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

      User Feedback
     ANDOR
    Aliases
    Disorders
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing NCKIPSD gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

      User Feedback
    Entrez Gene: 51517 HGNC: 15486 AceView: NCKIPSD Ensembl:ENSG00000213672 euGenes: HUgn51517
    ECgene: NCKIPSD H-InvDB: NCKIPSD

    Other Databases showing NCKIPSD gene

    (According to HUGE)
    About This Section

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    Specialized Databases showing NCKIPSD gene

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    ATLAS Chromosomes in Cancer entry for NCKIPSD Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
    for NCKIPSD gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from XenneX, Inc.)
    About This Section

      User Feedback    		Patent Information for NCKIPSD gene: ""
    Search GeneIP for patents involving NCKIPSD

    GeneCards and IP: ""
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