Aliases for NCKIPSD Gene
Aliases for NCKIPSD Gene
- NCK Interacting Protein With SH3 Domain 2 3 5
- Wiskott-Aldrich Syndrome Protein-Interacting Protein 3 4
- SH3 Protein Interacting With Nck, 90 KDa 2 3
- 90 KDa SH3 Protein Interacting With Nck 3 4
- Diaphanous Protein Interacting Protein 2 3
- 54 KDa Vimentin-Interacting Protein 3 4
- WASP-Interacting SH3-Domain Protein 3 4
- 54 KDa VacA-Interacting Protein 3 4
- SH3 Adapter Protein SPIN90 3 4
- Dia-Interacting Protein 1 3 4
- Dia Interacting Protein 2 3
- AF3P21 3 4
External Ids for NCKIPSD Gene
- HGNC: 15486
- Entrez Gene: 51517
- Ensembl: ENSG00000213672
- OMIM: 606671
- UniProtKB: Q9NZQ3
Previous GeneCards Identifiers for NCKIPSD Gene
- GC03M048661
- GC03M048675
Summaries for NCKIPSD Gene
-
The protein encoded by this gene is localized exclusively in the cell nucleus. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress fiber formation. The gene is involved in therapy-related leukemia by a chromosomal translocation t(3;11)(p21;q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
GeneCards Summary for NCKIPSD Gene
NCKIPSD (NCK Interacting Protein With SH3 Domain) is a Protein Coding gene. Diseases associated with NCKIPSD include Wiskott-Aldrich Syndrome and Lymphoid Leukemia. Among its related pathways are Innate Immune System and Regulation of actin dynamics for phagocytic cup formation. Gene Ontology (GO) annotations related to this gene include SH3 domain binding and cytoskeletal protein binding.
UniProtKB/Swiss-Prot for NCKIPSD Gene
-
Has an important role in stress fiber formation induced by active diaphanous protein homolog 1 (DRF1). Induces microspike formation, in vivo (By similarity). In vitro, stimulates N-WASP-induced ARP2/3 complex activation in the absence of CDC42 (By similarity). May play an important role in the maintenance of sarcomeres and/or in the assembly of myofibrils into sarcomeres. Implicated in regulation of actin polymerization and cell adhesion. Plays a role in angiogenesis.
Additional gene information for NCKIPSD Gene
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NCKIPSD Gene
Genomics for NCKIPSD Gene
GeneHancer (GH) Regulatory Elements for NCKIPSD Gene
Promoters and enhancers for NCKIPSD Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around NCKIPSD on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for NCKIPSD Gene
Genomic Locations for NCKIPSD Gene
- chr3:48,673,839-48,686,364
- (GRCh38/hg38)
- Size:
- 12,526 bases
- Orientation:
- Minus strand
- chr3:48,701,364-48,723,797
- (GRCh37/hg19)
Genomic View for NCKIPSD Gene
Genes around NCKIPSD on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 3p21.31 by Ensembl
- 3p21.31 by Entrez Gene
- 3p21.31 by HGNC
NCKIPSD Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for NCKIPSD Gene
Proteins for NCKIPSD Gene
-
Protein details for NCKIPSD Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9NZQ3-SPN90_HUMAN
- Recommended name:
- NCK-interacting protein with SH3 domain
- Protein Accession:
- Q9NZQ3
- B4DFL5
- Q6GU34
- Q6SPF3
- Q8TC10
- Q9UGM8
Protein attributes for NCKIPSD Gene
- Size:
- 722 amino acids
- Molecular mass:
- 78960 Da
- Quaternary structure:
-
- Associates with the intermediate filaments, vimentin and desmin. Binds the first and third SH3 domains of NCK. Binds the proline-rich domains of N-WASP through its SH3 domain (By similarity). Similarly, binds diaphanous protein homolog 1 (DRF1). Binds the SH3 domains of GRB2 through its proline-rich domains. Interacts with Helicobacter pylori toxin vacA. Isoform 4 interacts with FHOD1. Interacts with FASLG. Interacts with TMIGD2.
- SequenceCaution:
-
- Sequence=BAG57476.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
Protein Expression for NCKIPSD Gene
Post-translational modifications for NCKIPSD Gene
No Post-translational modifications
Other Protein References for NCKIPSD Gene
Antibody Products
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- Novus Biologicals Antibodies for NCKIPSD
-
Abcam antibodies for NCKIPSD
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-
Santa Cruz Biotechnology (SCBT) Antibodies for NCKIPSD
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Protein Products
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OriGene Purified Proteins for NCKIPSD
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- Browse Sino Biological Cell Lysates
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-
Abcam proteins for NCKIPSD
Assay Products
No data available for DME Specific Peptides for NCKIPSD Gene
Domains & Families for NCKIPSD Gene
Gene Families for NCKIPSD Gene
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- Disease related genes
- Predicted intracellular proteins
- Predicted membrane proteins
Protein Domains for NCKIPSD Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for NCKIPSD Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for NCKIPSD Gene
Function for NCKIPSD Gene
Molecular function for NCKIPSD Gene
- UniProtKB/Swiss-Prot Function:
- Has an important role in stress fiber formation induced by active diaphanous protein homolog 1 (DRF1). Induces microspike formation, in vivo (By similarity). In vitro, stimulates N-WASP-induced ARP2/3 complex activation in the absence of CDC42 (By similarity). May play an important role in the maintenance of sarcomeres and/or in the assembly of myofibrils into sarcomeres. Implicated in regulation of actin polymerization and cell adhesion. Plays a role in angiogenesis.
Phenotypes From GWAS Catalog for NCKIPSD Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 15095401 |
| GO:0008092 | cytoskeletal protein binding | NAS | 10619843 |
| GO:0017124 | SH3 domain binding | IEA | -- |
Phenotypes for NCKIPSD Gene
- MGI mutant phenotypes for NCKIPSD:
- inferred from 3 alleles
- GenomeRNAi human phenotypes for NCKIPSD:
Animal Model Products
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-
-
ViGene Biosciences lentiviral particle packaged cDNA for NCKIPSD gene
-
ViGene Biosciences ready-to-package AAV shRNAs for NCKIPSD gene
- Search ViGene Biosciences for NCKIPSD
CRISPR Products
-
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Vectors and viruses for KO, Activation, Repression, and more
-
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miRNA for NCKIPSD Gene
- miRTarBase miRNAs that target NCKIPSD
-
- hsa-mir-148b-3p (MIRT019269)
- hsa-mir-1226-3p (MIRT036524)
- hsa-mir-125a-5p (MIRT045772)
- hsa-let-7e-5p (MIRT051609)
- hsa-mir-6780a-5p (MIRT522327)
- hsa-mir-6779-5p (MIRT522328)
- hsa-mir-3689c (MIRT522329)
- hsa-mir-3689b-3p (MIRT522330)
- hsa-mir-3689a-3p (MIRT522331)
- hsa-mir-30b-3p (MIRT522332)
- hsa-mir-1273h-5p (MIRT522333)
- hsa-mir-4451 (MIRT522334)
- hsa-mir-6799-5p (MIRT522335)
- hsa-mir-6883-5p (MIRT522336)
- hsa-mir-6785-5p (MIRT522337)
- hsa-mir-4728-5p (MIRT522338)
- hsa-mir-149-3p (MIRT522339)
- hsa-mir-6086 (MIRT522340)
- hsa-mir-7106-5p (MIRT522341)
- hsa-mir-377-5p (MIRT522342)
- hsa-mir-98-5p (MIRT522343)
- hsa-mir-4500 (MIRT522344)
- hsa-mir-4458 (MIRT522345)
- hsa-let-7i-5p (MIRT522346)
- hsa-let-7g-5p (MIRT522347)
- hsa-let-7f-5p (MIRT522348)
- hsa-let-7d-5p (MIRT522349)
- hsa-let-7c-5p (MIRT522350)
- hsa-let-7b-5p (MIRT522351)
- hsa-let-7a-5p (MIRT522352)
- hsa-mir-4537 (MIRT522353)
- hsa-mir-3192-5p (MIRT522354)
- hsa-mir-6785-3p (MIRT522355)
- hsa-mir-6831-5p (MIRT522356)
- hsa-mir-3927-3p (MIRT522357)
- hsa-mir-7851-3p (MIRT522358)
- hsa-mir-490-3p (MIRT522359)
- hsa-mir-6513-5p (MIRT630358)
- hsa-mir-887-5p (MIRT630359)
- hsa-mir-3913-5p (MIRT630360)
- hsa-mir-3122 (MIRT630361)
- hsa-mir-450a-1-3p (MIRT630362)
- hsa-mir-6788-5p (MIRT630363)
- hsa-mir-30c-2-3p (MIRT630364)
- hsa-mir-30c-1-3p (MIRT630365)
- hsa-mir-7977 (MIRT630366)
- hsa-mir-3165 (MIRT630367)
- hsa-mir-6745 (MIRT630368)
- hsa-mir-363-5p (MIRT630369)
- hsa-mir-6804-5p (MIRT630370)
- hsa-mir-383-3p (MIRT630371)
- hsa-mir-4779 (MIRT630372)
- hsa-mir-6891-5p (MIRT630373)
- hsa-mir-3173-3p (MIRT630374)
- hsa-mir-920 (MIRT642009)
- hsa-mir-6726-5p (MIRT642010)
- hsa-mir-5591-5p (MIRT642011)
- hsa-mir-4300 (MIRT642012)
- hsa-mir-6090 (MIRT642013)
- hsa-mir-6827-5p (MIRT642014)
- hsa-mir-4524a-3p (MIRT642015)
- hsa-mir-4329 (MIRT642016)
- hsa-mir-4324 (MIRT642017)
- hsa-mir-4293 (MIRT642018)
- hsa-mir-4524b-3p (MIRT642019)
- hsa-mir-6514-3p (MIRT671382)
- hsa-mir-6847-3p (MIRT671383)
- hsa-mir-6811-3p (MIRT671384)
- hsa-mir-214-5p (MIRT671385)
- hsa-mir-6516-5p (MIRT680854)
- hsa-mir-455-3p (MIRT680855)
- hsa-mir-6499-3p (MIRT680856)
- hsa-mir-340-3p (MIRT765723)
- hsa-mir-383-5p (MIRT767571)
- hsa-mir-4251 (MIRT767965)
- hsa-mir-4684-5p (MIRT771004)
- hsa-mir-4768-3p (MIRT772106)
- hsa-mir-4772-5p (MIRT772216)
- hsa-mir-4786-5p (MIRT772306)
- hsa-mir-548c-3p (MIRT774324)
- hsa-mir-6761-5p (MIRT778470)
- hsa-mir-6771-3p (MIRT778633)
- hsa-mir-6827-3p (MIRT779921)
miRNA Products
- Search ViGene Biosciences for NCKIPSD
Inhibitory RNA Products
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Clone Products
- Sino Biological Human cDNA Clone for NCKIPSD
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available NCKIPSD gene related products
- orf clones - Search results for available NCKIPSD gene related products
- Applied Biological Materials Clones for NCKIPSD
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
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Horizon Cell Lines for NCKIPSD
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ViGene Biosciences adenoviral particle packaged cDNA for NCKIPSD gene
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ViGene Biosciences lentiviral particle packaged cDNA for NCKIPSD gene
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ViGene Biosciences ready-to-package AAV shRNAs for NCKIPSD gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for NCKIPSD Gene
Localization for NCKIPSD Gene
Subcellular locations from UniProtKB/Swiss-Prot for NCKIPSD Gene
- Nucleus. Note=Colocalizes with DRF1 at membrane ruffles, and with Nck at Z-disks in mature cardiac myocytes.
| Compartment | Confidence |
|---|---|
| cytoskeleton | 5 |
| nucleus | 5 |
| cytosol | 5 |
- Plasma membrane (4)
- Cytosol (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
| GO:0005829 | cytosol | TAS | -- |
| GO:0005882 | intermediate filament | NAS | 10619843 |
| GO:0008180 | colocalizes_with COP9 signalosome | IDA | 18850735 |
Pathways & Interactions for NCKIPSD Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Regulation of actin dynamics for phagocytic cup formation | ||
| 2 | Innate Immune System |
.61
|
|
| 3 | Signaling by Rho GTPases | ||
| 4 | Signaling by GPCR | ||
Pathways by source for NCKIPSD Gene
8 Reactome pathways for NCKIPSD Gene
Interacting Proteins for NCKIPSD Gene
Selected Interacting proteins:
Q9NZQ3-SPN90_HUMAN
ENSP00000294129
for NCKIPSD Gene via
MINT
STRING
IID
UniProtKB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006607 | NLS-bearing protein import into nucleus | TAS | 10648423 |
| GO:0007010 | cytoskeleton organization | NAS | 10619843 |
| GO:0007165 | signal transduction | TAS | 10648423 |
| GO:0010976 | positive regulation of neuron projection development | IEA | -- |
| GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | TAS | -- |
Transcripts for NCKIPSD Gene
mRNA/cDNA for NCKIPSD Gene
- (9) REFSEQ mRNAs :
- (9) Additional mRNA sequences :
- (544) Selected AceView cDNA sequences:
- (9) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for NCKIPSD Gene
CRISPR Products
-
OriGene CRISPR knockouts for NCKIPSD
- genomics-online: gRNA clones - Search results for available NCKIPSD gene related products
- Applied Biological Materials CRISPR for NCKIPSD
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for NCKIPSD
- GenScript: Design CRISPR guide RNA sequences for NCKIPSD
miRNA Products
- Search ViGene Biosciences for NCKIPSD
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for NCKIPSD
- Browse OriGene Inhibitory RNA Products For NCKIPSD
- genomics-online: shRNA clones - Search results for available NCKIPSD gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for NCKIPSD gene
Clone Products
- Sino Biological Human cDNA Clone for NCKIPSD
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
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- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for NCKIPSD
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available NCKIPSD gene related products
- orf clones - Search results for available NCKIPSD gene related products
- Applied Biological Materials Clones for NCKIPSD
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for NCKIPSD Gene
This gene is overexpressed in Peripheral blood mononuclear cells (25.3), Frontal cortex (15.9), and Platelet (6.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for NCKIPSD Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of NCKIPSD Gene:
NCKIPSDSOURCE GeneReport for Unigene cluster for NCKIPSD Gene:
Hs.655006mRNA Expression by UniProt/SwissProt for NCKIPSD Gene:
Q9NZQ3-SPN90_HUMAN
Tissue specificity:
Highest expression in heart, brain, skeletal muscle, kidney and liver. Lower levels in placenta, lung, small intestine and leukocytes. Weak expression in colon, thymus and spleen.
Evidence on tissue expression from TISSUES for NCKIPSD Gene
- Nervous system(4.5)
- Blood(4.3)
- Heart(4.2)
- Skin(4.2)
- Bone marrow(4.1)
- Liver(4.1)
Primer Products
-
OriGene qPCR primer pairs for NCKIPSD
-
OriGene qPCR primer pairs and template standards for NCKIPSD
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No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for NCKIPSD Gene
Orthologs for NCKIPSD Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | NCKIPSD 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | NCKIPSD 34 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | NCKIPSD 33 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Nckipsd 33 16 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Nckipsd 33 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | NCKIPSD 34 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | NCKIPSD 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | NCKIPSD 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | NCKIPSD 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | nckipsd 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | nckipsd 33 34 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG2258 34 |
|
OneToOne | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToOne |
- Species where no ortholog for NCKIPSD was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for NCKIPSD Gene
(5) SIMAP similar genes for NCKIPSD Gene using alignment to 7 proteins:
No data available for Paralogs for NCKIPSD Gene
Variants for NCKIPSD Gene
| SNP ID | Clin | Chr 03 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000603034 | -- | 48,670,764(-) | G/A | genic_downstream_transcript_variant, intron_variant | |
| rs1000722507 | -- | 48,669,127(-) | C/T | genic_downstream_transcript_variant, intron_variant | |
| rs1000799645 | -- | 48,664,883(-) | G/A | coding_sequence_variant, genic_downstream_transcript_variant, synonymous_variant | |
| rs1000961186 | -- | 48,664,715(-) | T/C | coding_sequence_variant, genic_downstream_transcript_variant, missense_variant | |
| rs1001169723 | -- | 48,664,436(-) | G/A | 3_prime_UTR_variant, genic_downstream_transcript_variant |
Residual Variation Intolerance Score:
70.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.31;
41.20% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for NCKIPSD Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NCKIPSD Gene
Disorders for NCKIPSD Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| wiskott-aldrich syndrome |
|
|
| lymphoid leukemia |
|
|
Search NCKIPSD in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
SPN90_HUMAN- Note=A chromosomal aberration involving NCKIPSD/AF3p21 is found in therapy-related leukemia. Translocation t(3;11)(p21;q23) with KMT2A/MLL1. {ECO:0000269 PubMed:10648423}.
Additional Disease Information for NCKIPSD
No data available for Genatlas for NCKIPSD Gene
Publications for NCKIPSD Gene
- Novel SH3 protein encoded by the AF3p21 gene is fused to the mixed lineage leukemia protein in a therapy-related leukemia with t(3;11) (p21;q23). (PMID: 10648423) Sano K … Nakamura H (Blood 2000) 2 3 4 22 58
- Genomic organization, tissue expression, and cellular localization of AF3p21, a fusion partner of MLL in therapy-related leukemia. (PMID: 11241789) Hayakawa A … Sano K (Genes, chromosomes & cancer 2001) 3 4 22 58
- SPIN90 (SH3 protein interacting with Nck, 90 kDa), an adaptor protein that is developmentally regulated during cardiac myocyte differentiation. (PMID: 11278500) Lim CS … Song WK (The Journal of biological chemistry 2001) 3 4 22 58
- The VacA toxin of Helicobacter pylori identifies a new intermediate filament-interacting protein. (PMID: 10619843) de Bernard M … Montecucco C (The EMBO journal 2000) 2 3 4 58
- Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening. (PMID: 19807924) Voss M … Janssen O (BMC immunology 2009) 3 4 58
Products for NCKIPSD Gene
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- OriGene CRISPR knockouts for NCKIPSD
- OriGene ORF clones in human for NCKIPSD
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For NCKIPSD
- GenScript: Next-day shipping of latest version cDNA ORF clones for NCKIPSD in any vector
- GenScript Custom Purified and Recombinant Proteins Services for NCKIPSD
- GenScript Custom Assay Services for NCKIPSD
- GenScript Custom overexpressing Cell Line Services for NCKIPSD
- GenScript: Design CRISPR guide RNA sequences for NCKIPSD
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for NCKIPSD
- Sino Biological Human cDNA Clone for NCKIPSD
- Sino Biological Recombinant Proteins for NCKIPSD
- Browse Sino Biological Cell Lysates
- Sino Biological Antibodies for NCKIPSD
- Browse Sino Biological Assays
- Browse Sino Biological ELISA Kits
- Browse Sino Biological ELISA Pair Sets
- Browse Sino Biological CRO Services
- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for NCKIPSD
- Novus Biologicals proteins and lysates for NCKIPSD
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for NCKIPSD
- Abcam proteins for NCKIPSD
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Browse Antibodies at Cloud-Clone Corp.
- Browse Proteins at Cloud-Clone Corp.
- Browse Assay Kits at Cloud-Clone Corp.
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for NCKIPSD
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for NCKIPSD
- VectorBuilder custom plasmid, inducible vectors for NCKIPSD
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for NCKIPSD
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 38 available NCKIPSD Antibodies ranked by validation data
- Compare Top NCKIPSD Antibodies
- antibodies-online: Search results for 2 available NCKIPSD Elisa Kits ranked by validation data
- Compare Top NCKIPSD Elisa Kits
- Recommended
- antibodies-online: Search results for 6 available NCKIPSD Proteins ranked by validation data
- Compare Top NCKIPSD Proteins
- GeneTex NCKIPSD antibody for NCKIPSD
- Search GeneTex for Proteins for NCKIPSD
- ViGene Biosciences adenoviral particle packaged cDNA for NCKIPSD gene
- ViGene Biosciences lentiviral particle packaged cDNA for NCKIPSD gene
- ViGene Biosciences ready-to-package AAV shRNAs for NCKIPSD gene
- Search ViGene Biosciences for NCKIPSD
- Santa Cruz Biotechnology (SCBT) Antibodies for NCKIPSD
- Search Santa Cruz Biotechnology (SCBT) for NCKIPSD siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for NCKIPSD
- Horizon Cell Lines for NCKIPSD
- genomics-online: cdna clones - Search results for available NCKIPSD gene related products
- orf clones - Search results for available NCKIPSD gene related products
- genomics-online: gRNA clones - Search results for available NCKIPSD gene related products
- genomics-online: primer clones - Search results for available NCKIPSD gene related products
- genomics-online: shRNA clones - Search results for available NCKIPSD gene related products
Sources for NCKIPSD Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew