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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NCKAP1L Gene

protein-coding   GIFtS: 53
GCID: GC12P054891

NCK-Associated Protein 1-Like

(Previous name: hematopoietic protein 1)
(Previous symbol: HEM1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
NCK-Associated Protein 1-Like1 2
HEM11 2 3 5
Hematopoietic Protein 11 2 3
Membrane-Associated Protein HEM-12 3

External Ids:    HGNC: 48621   Entrez Gene: 30712   Ensembl: ENSG000001233387   OMIM: 1411805   UniProtKB: P551603   

Export aliases for NCKAP1L gene to outside databases

Previous GC identifers: GC12P053178 GC12P051930


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NCKAP1L Gene:
This gene encodes a member of the HEM family of tissue-specific transmembrane proteins which are highly conserved
from invertebrates through mammals. This gene is only expressed in hematopoietic cells. The encoded protein is a
part of the Scar/WAVE complex which plays an important role in regulating cell shape in both metazoans and
plants. Alternatively spliced transcript variants encoding different isoforms have been found.(provided by
RefSeq, May 2010)

GeneCards Summary for NCKAP1L Gene: 
NCKAP1L (NCK-associated protein 1-like) is a protein-coding gene. Diseases associated with NCKAP1L include rectum cancer, and hypochromic anemia, and among its related super-pathways are Regulation of Actin Cytoskeleton. GO annotations related to this gene include Rac GTPase activator activity and protein complex binding. An important paralog of this gene is NCKAP1.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NC_018923.2  NT_029419.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NCKAP1L gene promoter:
         TBP   Pax-6   AREB6   POU2F1   FOXJ2 (long isoform)   POU2F1a   TFIID   FOXJ2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNCKAP1L promoter sequence
   Search SABiosciences Chromatin IP Primers for NCKAP1L

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NCKAP1L


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q13.1   Ensembl cytogenetic band:  12q13.13   HGNC cytogenetic band: 12q13.1

NCKAP1L Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NCKAP1L gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P054891:  view genomic region     (about GC identifiers)

Start:
54,891,495 bp from pter      End:
54,937,726 bp from pter
Size:
46,232 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NCKPL_HUMAN, P55160 (See protein sequence)
Recommended Name: Nck-associated protein 1-like  
Size: 1127 amino acids; 128153 Da
Subcellular location: Cell membrane; Single-pass membrane protein; Cytoplasmic side (Probable)
Sequence caution: Sequence=AAA35964.1; Type=Erroneous initiation;
Secondary accessions: B4DUT5 Q52LW0
Alternative splicing: 2 isoforms:  P55160-1   P55160-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NCKAP1L: NX_P55160

Explore proteomics data for NCKAP1L at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P55160

  • NCKAP1L Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NCKAP1L Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001171905.1  NP_005328.2  

    ENSEMBL proteins: 
     ENSP00000293373   ENSP00000447246   ENSP00000445596  

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    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ----
    GO:0005829cytosol IDA16417406
    GO:0005887integral to plasma membrane NAS1932118
    GO:0016020membrane TAS1932118
    GO:0031209SCAR complex IDA16417406

    NCKAP1L for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR019137 Nck-associated_protein-1

    Graphical View of Domain Structure for InterPro Entry P55160

    ProtoNet protein and cluster: P55160

    UniProtKB/Swiss-Prot: NCKPL_HUMAN, P55160
    Similarity: Belongs to the HEM-1/HEM-2 family


    NCKAP1L for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003700sequence-specific DNA binding transcription factor activity ----
    GO:0003707steroid hormone receptor activity ----
    GO:0005515protein binding IPI16417406
    GO:0030295protein kinase activator activity IMP16417406
    GO:0030675Rac GTPase activator activity IMP16417406
         
    NCKAP1L for ontologies           About GeneDecksing


    Phenotypes:
         4 GenomeRNAi human phenotypes for NCKAP1L:
     Decreased BPV1 E2 protein expr  Decreased Hepatitis C virus re  Increased HPV18 LCR reporter a  Increased S DNA content 

         11 MGI mutant phenotypes (inferred from 1 allele(MGI details for Nckap1l):
     cardiovascular system  cellular  growth/size  hematopoietic system  homeostasis/metabolism 
     immune system  liver/biliary system  other  renal/urinary system  reproductive system 
     respiratory system 

    NCKAP1L for phenotypes           About GeneDecksing

    Animal Models:
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for NCKAP1L About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Regulation of Actin Cytoskeleton
    Regulation of actin cytoskeleton0.57

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1         Kegg Pathway  (Kegg details for NCKAP1L):
        Regulation of actin cytoskeleton


    NCKAP1L for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NCKAP1L

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    5/12 Interacting proteins for NCKAP1L (P551602, 3 ENSP000002933734) via UniProtKB, MINT, STRING, and/or I2D (see all 12)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GAS7O608612, 3, ENSP000003226084MINT-72921 I2D: score=3 STRING: ENSP00000322608
    PRPF40AO754003I2D: score=2 
    RAC2ENSP000002490714STRING: ENSP00000249071
    RAC3ENSP000003042834STRING: ENSP00000304283
    WASF1ENSP000003524254STRING: ENSP00000352425
    About this table

    Gene Ontology (GO): 5/32 biological process terms (GO ID links to tree view) (see all 32):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001782B cell homeostasis ISS--
    GO:0002262myeloid cell homeostasis ISS--
    GO:0006461protein complex assembly ISS--
    GO:0006935chemotaxis IDA16417406
    GO:0030011maintenance of cell polarity IMP16417406

    NCKAP1L for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NCKAP1L (NCKPL)

    Search CenterWatch for drugs/clinical trials and news about NCKAP1L / NCKPL

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NCKAP1L gene (2 alternative transcripts): 
    NM_001184976.1  NM_005337.4  

    Unigene Cluster for NCKAP1L:

    NCK-associated protein 1-like
    Hs.182014  [show with all ESTs]
    Unigene Representative Sequence: NM_005337
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000293373(uc001sgc.4 uc010sox.2 uc010soy.2) ENST00000548221
    ENST00000547500 ENST00000545638 ENST00000552211 ENST00000548916 ENST00000549451
    ENST00000548980
    miRNA
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    hsa-miR-194* hsa-miR-99a* hsa-miR-99b* hsa-miR-1245 hsa-miR-3159 hsa-miR-889 hsa-miR-3682-3p hsa-miR-1322
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    Additional mRNA sequence: 

    AK300783.1 AK314012.1 BC001604.2 BC064997.1 BC084547.1 BC093769.2 BC093771.1 M58285.1 

    12 DOTS entries:

    DT.110756  DT.95163588  DT.100841504  DT.86859689  DT.95163589  DT.92016724  DT.100694560  DT.100778358 
    DT.404958  DT.65284815  DT.95241684  DT.98082923 

    24/183 AceView cDNA sequences (see all 183):

    N47020 BX482901 BX398308 BG259380 CN478513 BQ433466 CA390313 AI357311 
    BM705200 BX395541 NM_005337 BE397676 BX482767 AW468641 CR600496 BE676106 
    BU630166 AW445205 AI718434 BX395542 AW575485 CB054403 BG389488 AL119153 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for NCKAP1L (see all 6)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16a · 16b ^ 17 ^ 18a · 18b ^ 19 ^ 20 ^ 21a · 21b ^
    SP1:                          -                             -                                               -                                                   
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 22a · 22b ^ 23 ^ 24 ^ 25 ^ 26 ^ 27a · 27b ^ 28 ^ 29a · 29b ^ 30 ^ 31 ^ 32
    SP1:        -                                                     -                     
    SP2:                                                                                    
    SP3:                                                                                    
    SP4:                                                                                    
    SP5:                                                                                    


    ECgene alternative splicing isoforms for NCKAP1L

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NCKAP1L expression in normal human tissues (normalized intensities)      NCKAP1L embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGTGAATTTT
    NCKAP1L Expression
    About this image


    NCKAP1L expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/5 selected tissues (see all 5) fully expand
     
     Blood (Hematopoietic System)    fully expand to see all 12 entries
             Plasmacytoid Dendritic cells Peripheral Blood
             Peripheral blood Pan-T Cells   
     
     Liver (Hepatobiliary System)    fully expand to see all 2 entries
             Fetal Liver CD36+ Cells   
     
     Umbilical Cord (Extraembryonic Tissues)    fully expand to see all 2 entries
             Cord Blood Pan-T Cells   
     
     Lymph (Hematopoietic System)
             LYMPH NODE   
     
     Thymus (Hematopoietic System)

    See NCKAP1L Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NCKAP1L

    SOURCE GeneReport for Unigene cluster: Hs.182014

    UniProtKB/Swiss-Prot: NCKPL_HUMAN, P55160
    Tissue specificity: Expressed only in cells of hematopoietic origin

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NCKAP1L

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for NCKAP1L gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nckap1l1 , 5 NCK associated protein 1 like1, 5 89.68(n)1
    94.85(a)1
      15 (58.96 cM)5
    1058551  NM_153505.41  NP_705725.11 
     1034538255 
    chicken
    (Gallus gallus)
    Aves NCKAP1L1 NCK-associated protein 1-like 71.22(n)
    72.23(a)
      425499  NM_001031339.1  NP_001026510.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    70(a)
    69(a)
    many → 1
    many → 1
    GL343252.1(406967-471863)
    GL343252.1(359647-399666)
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.261032 Transcribed sequence with weak similarity to protein more 74.26(n)    CD604658.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Hem6
    HEM-protein
    47(a)
    1 → many
    3L(22277454-22281295)
    worm
    (Caenorhabditis elegans)
    Secernentea gex-36
    Membrane-associated protein gex-3
    35(a)
    1 → many
    IV(12404431-12408689)


    ENSEMBL Gene Tree for NCKAP1L (if available)
    TreeFam Gene Tree for NCKAP1L (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NCKAP1L gene
    NCKAP12  
    1 SIMAP similar gene for NCKAP1L using alignment to 5 protein entries:     NCKPL_HUMAN (see all proteins):
    NCKAP1

    NCKAP1L for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1032 SNPs in NCKAP1L are shown (see all 1032)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1478837571,2
    C,Funtested154925604(+) GACTTC/TGGGAG 4 R W mis11Minor allele frequency- T:0.00NA 4552
    rs1152426651,2
    F--54889686(+) GATACG/AGAAAA 1 -- us2k11Minor allele frequency- A:0.03WA 118
    rs171127831,2
    C,F,H--54889698(+) GGGAAT/AGATTA 1 -- us2k1 tfbs39Minor allele frequency- A:0.06NA NS EA WA 800
    rs1477030841,2
    --54889837(+) GTTACA/GGAGTT 1 -- us2k10--------
    rs1174392371,2
    F--54889908(+) TTAAGG/CGTGAT 1 -- us2k11Minor allele frequency- C:0.01NA 120
    rs37823991,2
    C,A,H--54889939(+) TCTTGA/GTTAAT 1 -- us2k14Minor allele frequency- G:0.11CSA WA NA EA 360
    rs1408366381,2
    --54890015(+) ATTTAC/TTGAGT 1 -- us2k10--------
    rs177257371,2
    C,F,H--54890140(+) AGACTC/TGCCTA 1 -- us2k126Minor allele frequency- T:0.10NA NS EA WA 2910
    rs1423126151,2
    --54890198(+) CATCCA/GTAAAT 1 -- us2k10--------
    rs123009651,2
    H--54890328(+) gggtcC/Ttaaga 1 -- us2k14Minor allele frequency- T:0.00NS EA 418

    HapMap Linkage Disequilibrium report for NCKAP1L (54891495 - 54937726 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for NCKAP1L:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv525674CNV Loss19592680
    nsv508674CNV Loss20534489
    nsv832421CNV Gain17160897

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 141180    OMIM disorders: --

    6 diseases for NCKAP1L:    About MalaCards
    rectum cancer    hypochromic anemia    b-cell chronic lymphocytic leukemia    chronic lymphocytic leukemia
    anemia    leukemia

    1 disease from the University of Copenhagen DISEASES database for NCKAP1L:
    Hypochromic anemia

    NCKAP1L for disorders           About GeneDecksing


    Export disorders for NCKAP1L gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NCKAP1L gene, integrated from 9 sources (see all 22):
    (articles sorted by number of sources associating them with NCKAP1L)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The HEM proteins: a novel family of tissue-specific transmembrane proteins expressed from invertebrates through mammals with an essential function in oogenesis. (PubMed id 7643388)1, 2 Baumgartner S.... Hromas R. (1995)
    2. Hem-1, a potential membrane protein, with expression restricted to blood cells. (PubMed id 1932118)1, 3 Hromas R....Kaushansky K. (1991)
    3. Hem-1 complexes are essential for Rac activation, actin polymerization, and myosin regulation during neutrophil chemotaxis. (PubMed id 16417406)1, 9 Weiner O.D....Kirschner M.W. (2006)
    4. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)
    5. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    6. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (2012)
    7. NOTCH1 nuclear interactome reveals key regulators of i ts transcriptional activity and oncogenic function. (PubMed id 23022380)1 Yatim A....Benkirane M. (2012)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    9. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    10. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 3071 HGNC: 4862 AceView: HEM1 Ensembl:ENSG00000123338 euGenes: HUgn3071
    ECgene: NCKAP1L Kegg: 3071 H-InvDB: NCKAP1L

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NCKAP1L Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NCKAP1L gene:
    Search GeneIP for patents involving NCKAP1L

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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