Aliases for NCKAP1L Gene
External Ids for NCKAP1L Gene
Previous HGNC Symbols for NCKAP1L Gene
Previous GeneCards Identifiers for NCKAP1L Gene
This gene encodes a member of the HEM family of tissue-specific transmembrane proteins which are highly conserved from invertebrates through mammals. This gene is only expressed in hematopoietic cells. The encoded protein is a part of the Scar/WAVE complex which plays an important role in regulating cell shape in both metazoans and plants. Alternatively spliced transcript variants encoding different isoforms have been found.[provided by RefSeq, May 2010]
GeneCards Summary for NCKAP1L Gene
NCKAP1L (NCK Associated Protein 1 Like) is a Protein Coding gene. Among its related pathways are Regulation of actin dynamics for phagocytic cup formation and Interleukin-3, 5 and GM-CSF signaling. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and protein complex binding. An important paralog of this gene is NCKAP1.