Aliases for NCKAP1L Gene
External Ids for NCKAP1L Gene
Previous HGNC Symbols for NCKAP1L Gene
Previous GeneCards Identifiers for NCKAP1L Gene
This gene encodes a member of the HEM family of tissue-specific transmembrane proteins which are highly conserved from invertebrates through mammals. This gene is only expressed in hematopoietic cells. The encoded protein is a part of the Scar/WAVE complex which plays an important role in regulating cell shape in both metazoans and plants. Alternatively spliced transcript variants encoding different isoforms have been found.[provided by RefSeq, May 2010]
GeneCards Summary for NCKAP1L Gene
NCKAP1L (NCK Associated Protein 1 Like) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Regulation of actin dynamics for phagocytic cup formation. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and protein complex binding. An important paralog of this gene is NCKAP1.