Aliases for NCKAP1 Gene
External Ids for NCKAP1 Gene
Previous GeneCards Identifiers for NCKAP1 Gene
GeneCards Summary for NCKAP1 Gene
NCKAP1 (NCK Associated Protein 1) is a Protein Coding gene. Diseases associated with NCKAP1 include Nance-Horan Syndrome. Among its related pathways are Regulation of actin dynamics for phagocytic cup formation and Interleukin-3, 5 and GM-CSF signaling. GO annotations related to this gene include protein complex binding and Rac GTPase binding. An important paralog of this gene is NCKAP1L.
UniProtKB/Swiss-Prot for NCKAP1 Gene
Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1.