NCK2 Gene
protein-coding GIFtS: 64
GCID: GC02P106361
|
|
NCK adaptor protein 2
| |
Aliases
for NCK2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| NCK Adaptor Protein 21 2 3 | | SH2/SH3 Adaptor Protein NCK-Beta2 3 | | NCKbeta1 2 | | Cytoplasmic Protein NCK22 | | Growth Factor Receptor-Bound Protein 42 3 | | Noncatalytic Region Of Tyrosine Kinase, Beta2 | | GRB42 3 | | Nck-23 |
Export aliases for NCK2 gene to outside databasesPrevious GC identifers: GC02P104297 GC02P104885 GC02P106037 GC02P106054 GC02P105926 GC02P105727 GC02P100201 |
Summaries
for NCK2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for NCK2:
This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involvedin the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein isbelieved to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding differentisoforms, have been characterized. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: NCK2_HUMAN, O43639Function: Adapter protein which associates with tyrosine-phosphorylated growth factor receptors or their cellularsubstrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role inELK1-dependent transcriptional activation in response to activated Ras signaling
Gene Wiki entry for NCK2
|
Genomic Views
for NCK2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_022171.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the NCK2 gene promoter:
E2F-4 E2F-3a E2F-5 Pax-5 E2F-2 GATA-1 E2F E2F-1 Nkx6-1 COMP1
Other transcription factors
Search SABiosciences Chromatin IP Primers for NCK2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NCK2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2q12 Ensembl cytogenetic band: 2q12.2 HGNC cytogenetic band: 2q12NCK2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02P106361: view genomic region
(about GC identifiers)
Start:
|
106,361,354 bp from pter |
End:
|
106,510,730 bp from pter |
Size:
|
149,377 bases |
Orientation:
|
plus strand |
|
Proteins
for NCK2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: NCK2_HUMAN, O43639 (See
protein sequence)Recommended Name: Cytoplasmic protein NCK2 Size: 380 amino acids; 42915 Da
Subunit: Interacts with DOCK1, LIMS1 and TGFB1I1. Part of a complex containing PPP1R15B, PP1 and NCK2. Interacts withFASLG (By similarity). Interacts with AXL. Interacts with PAK1, PKN2 and SOS1. Interacts (via SH2 domain) with EGFR.Interacts (via SH2 domain) with DDR1
Subcellular location: Cytoplasm. Endoplasmic reticulum
6/9 PDB 3D structures from  and Proteopedia  for NCK2 (see all 9):1U5S (3D)
1WX6 (3D)
1Z3K (3D)
2B86 (3D)
2CIA (3D)
2FRW (3D)
Secondary accessions: D3DVK1 Q9BWN9 Q9UIC3Explore the universe of human proteins at neXtProt for NCK2: NX_O43639
Post-translational modifications:
Phosphorylated1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O43639
NCK2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001004720.1 NP_001004722.1 NP_003572.2
ENSEMBL proteins: ENSP00000233154 ENSP00000377017 ENSP00000431109 ENSP00000408040 ENSP00000377018 ENSP00000410428 Reactome Protein details: O43639
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
NCK2 for ontologies About GeneDecksing
NCK2 Antibody Products:
Assay Products for NCK2: |
Protein
Domains /
Families
for NCK2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NCK2 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O43639ProtoNet protein and cluster: O43639 2 Blocks protein families: IPB000980 SH2 domain signature IPB001452 SH3 domain signature
UniProtKB/Swiss-Prot: NCK2_HUMAN, O43639Similarity: Contains 1 SH2 domainSimilarity: Contains 3 SH3 domains |
Function
for NCK2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: NCK2_HUMAN, O43639Function: Adapter protein which associates with tyrosine-phosphorylated growth factor receptors or their cellularsubstrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role inELK1-dependent transcriptional activation in response to activated Ras signaling Genatlas biochemistry entry for NCK2:transduction adaptator protein 2 interacting with EGFR and PDGFR
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NCK2 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): NCK2 (NM_003581) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NCK2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NCK2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NCK2 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
NCK2 for ontologies About GeneDecksing
4 GenomeRNAi human phenotypes for NCK2:
Animal Models:
Mouse knock-out Nck2tm1Paw for NCK2
9 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Nck2):
NCK2 for phenotypes About GeneDecksing
|
Pathways & Interactions
for NCK2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/33 super-pathways (see all 33) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Cytoskeleton remodeling_Reverse signaling by ephrin B | | | 2 | Activation of Rac | | | 3 | Axon guidance | | | 4 | Cell adhesion_Ephrins signaling | | | 5 | Pathogenic Escherichia coli infection | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3 EMD Millipore Pathways for NCK2
5/13 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for NCK2 (see all 13)
3  GeneGo (Thomson Reuters) Pathways for NCK2
5/9  BioSystems Pathways for NCK2 (see all 9)
5/9 
Reactome Pathways for NCK2 (see all 9)
4 
Kegg Pathways (Kegg details for NCK2):
NCK2 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for NCK2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/136 Interacting proteins for NCK2 (O436391, 2, 3 ENSP000002331544) via UniProtKB, MINT, STRING, and/or I2D (see all 136)About this table
Gene Ontology (GO): 5/14 biological process terms (GO ID links to tree view) (see all 14): About this table
NCK2 for ontologies About GeneDecksing
|
Drugs & Compounds
for NCK2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
NCK2 for compounds About GeneDecksing
 Browse Tocris compounds for NCK2
1 Novoseek chemical compound relationship for NCK2 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| tyrosine |
33.8 |
2 |
10026169 (1), 11950595 (1) |
Search CenterWatch for drugs/clinical trials and news about NCK2
|
Transcripts
for NCK2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for NCK2 gene (3 alternative transcripts): NM_001004720.2 NM_001004722.3 NM_003581.4 Unigene Cluster for NCK2: NCK adaptor protein 2 Hs.529244 [show with all ESTs]Unigene Representative Sequence: NM_0035816 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000233154(uc002tdg.3) ENST00000393348 ENST00000522586 ENST00000425756
ENST00000393349(uc002tdi.3) ENST00000451463(uc002tdh.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NCK2 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NCK2 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): NCK2 (NM_003581) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NCK2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NCK2 |
Additional cDNA sequence: AF043119.1 AF047487.1 BC000103.2 BC007195.1 BC033176.1 8 DOTS entries: DT.100793391 DT.95206648 DT.99946387 DT.91832436 DT.100793392 DT.95206654 DT.97787126 DT.97796366 24/270 AceView cDNA sequences (see all 270): BM967154 BM560362 BM912771 BG479122 BQ887822 BG763695 CD674606 BM557586 AW009661 BQ423876 CK906244 BQ897760 BM559035 BM423369 BM911479 BQ070774 BM811586 BU162526 BE279723 AI383371 BU163786 BE302645 CR594525 BM550470
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for NCK2 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b |
|---|
|
| SP1: | | | | | | | | | | | |
| SP2: | | | | | - | | | | | |
ECgene alternative splicing isoforms for NCK2
|
Expression
for NCK2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| NCK2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCTCCCGGAC
About this image
See NCK2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NCK2
SOURCE GeneReport for Unigene cluster: Hs.529244
UniProtKB/Swiss-Prot: NCK2_HUMAN, O43639Tissue specificity: Ubiquitous
SABiosciences Expression via Pathway-Focused PCR Arrays including NCK2:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NCK2
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NCK2 |
Orthologs
for NCK2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for NCK2 gene from 6/19 species (see all 19) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
NCK21 |
NCK adaptor protein 2 |
78.33(n)
92.89(a) |
|
418727 NM_001030814.1 NP_001025985.1 |
lizard
(Anolis carolinensis) |
Reptilia |
NCK26 |
-- |
92(a) |
1 ↔ 1 |
3(108603203-108627966) |
African clawed frog
(Xenopus laevis) |
Amphibia |
AY354455.12 |
-- |
75.5(n) |
|
AY354455.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
BC046872.12 |
-- |
78.44(n) |
|
393972 BC046872.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
dock3 |
axon guidance SH3/SH2 adaptor protein |
42(a) |
|
2 21D3 -- |
worm
(Caenorhabditis elegans) |
Secernentea |
ZK470.5b3
nck-11 |
Protein NCK-11 |
42(a)
(best of 2)3
51.15(n)1
48.21(a)1 |
|
X(4184350-4185897)3
1806901 NM_076305.41 NP_508706.21 |
ENSEMBL Gene Tree for NCK2 (if available)
TreeFam Gene Tree for NCK2 (if available) |
Paralogs
for NCK2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for NCK2 gene
- GRAP2 GRAPL2 NCK12 GRAP22 GRB22
18/19 SIMAP similar genes for NCK2 using alignment to 6 protein entries: NCK2_HUMAN (see all proteins)
(see all similar genes):NCK1 EPS8 EPS8L2 FYN EPS8L1 HCK
BLK FGR YES1 STAC2 SPTAN1 LYN
BTK LCK CSK SH3BP4 ARHGEF7 BCR/ABL fusion
NCK2 for paralogs About GeneDecksing
|
Genomic Variants
for NCK2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for NCK2 (106361354 - 106510730 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 12 variations for NCK2
11 CNVs: 32339 89857 97930 89858 78678 0021 78679 68104 89859 89856 68103
1 Indel: 74187 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NCK2 |
|
Disorders
/ Diseases
for NCK2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
NCK2 for disorders About GeneDecksing
OMIM gene information: 604930
OMIM disorders: --
10  diseases for NCK2: About MalaCardslow tension glaucoma craniofrontonasal syndrome glaucoma down syndrome
hepatitis b ataxia hepatitis cerebritis
melanoma neuronitis
2 diseases from the University of Copenhagen DISEASES database for NCK2:Low tension glaucoma Craniofrontonasal syndrome Human Genome Epidemiology (HuGE) Navigator: NCK2 (3 documents)
Export disorders for NCK2 gene to outside databases
|
Publications
for NCK2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for NCK2 gene, integrated from 9 sources (see all 56):
(articles sorted by number of sources associating them with NCK2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification of Nck family genes, chromosomal localization, expression, and signaling specificity. (PubMed id 9737977)1, 2, 3 Chen M....Li W. (1998)
- Identification of Grb4/Nckbeta, a src homology 2 and 3 domain-containing adapter protein having similar binding and biological properties to Nck. (PubMed id 10026169)1, 2, 9 Braverman L.E. and Quilliam L.A. (1999)
- Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening. (PubMed id 19807924)1, 2 Voss M....Janssen O. (2009)
- Structural insight into the binding diversity between the human Nck2 SH3 domains and proline-rich proteins. (PubMed id 16752908)1, 3 Liu J....Song J. (2006)
- Nck in a complex containing the catalytic subunit of protein phosphatase 1 regulates eukaryotic initiation factor 2alpha signaling and cell survival to endoplasmic reticulum stress. (PubMed id 16835242)1, 2 Latreille M. and Larose L. (2006)
- Pinpointing phosphotyrosine-dependent interactions downstream of the collagen receptor DDR1. (PubMed id 16337946)1, 2 Koo D.H....Vogel W.F. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Interaction of Axl receptor tyrosine kinase with C1-TEN, a novel C1 domain-containing protein with homology to tensin. (PubMed id 12470648)1, 2 Hafizi S.... Dahlbaeck B. (2002)
- Identification and kinetic analysis of the interaction between Nck-2 and DOCK180. (PubMed id 11240126)1, 2 Tu Y.... Wu C. (2001)
- Nck-2, a novel Src homology2/3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathways. (PubMed id 9843575)1, 2 Tu Y.... Wu C. (1998)
|
External Searches for NCK2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing NCK2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing NCK2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NCK2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for NCK2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for NCK2 gene:
Search GeneIP for patents involving NCK2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for NCK2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for NCK2 | | OriGene shRNA RFP for NCK2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NCK2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NCK2 | | | OriGene Protein Over-expression Lysate for NCK2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for NCK2 | | OriGene 3'-UTR Clone for NCK2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NCK2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NCK2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for NCK2 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for NCK2 | | OriGene Custom Protein Services for NCK2 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NCK2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NCK2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NCK2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NCK2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NCK2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NCK2 |
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| | | | Search Tocris compounds for NCK2 |
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 | | | NCK2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NCK2 |
|  |  |  | | | | ThermoFisher Antibodies for NCK2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NCK2 |
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