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Aliases for NCBP2L Gene

Aliases for NCBP2L Gene

  • Nuclear Cap Binding Protein Subunit 2 Like 2 3
  • Nuclear Cap-Binding Protein Subunit 2-Like 3
  • Nuclear Cap Binding Protein Subunit 2-Like 5
  • DJ820B18.1 3

External Ids for NCBP2L Gene

Previous GeneCards Identifiers for NCBP2L Gene

  • GC0XP106825
  • GC0XU900756
  • GC0XP107037

Summaries for NCBP2L Gene

GeneCards Summary for NCBP2L Gene

NCBP2L (Nuclear Cap Binding Protein Subunit 2 Like) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and RNA cap binding. An important paralog of this gene is NCBP2.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NCBP2L Gene

Genomics for NCBP2L Gene

Regulatory Elements for NCBP2L Gene

Enhancers for NCBP2L Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XG107825 1.1 FANTOM5 ENCODE 5.3 +51.6 51566 2.7 PKNOX1 ARNT ZSCAN4 SIN3A FEZF1 ZNF366 SP3 PRDM6 GLIS1 WT1 NCBP2L LOC101928335 MID2 GC0XM107885
GH0XG107774 1.5 Ensembl ENCODE dbSUPER 0.7 +0.8 825 3.0 PKNOX1 ATF1 ZFP64 SIN3A FEZF1 GLIS2 DEK ZNF263 SP3 REST MID2 NCBP2L TSC22D3
GH0XG107733 1.9 FANTOM5 Ensembl ENCODE dbSUPER 0.3 -36.0 -36003 10.9 HDGF PKNOX1 FOXA2 ARNT SIN3A FEZF1 ZNF2 YY1 ZNF263 SP3 TSC22D3 GC0XM107728 NCBP2L
GH0XG107773 0.7 ENCODE dbSUPER 0.7 -1.5 -1494 0.2 ZNF547 BCL6B NCBP2L GC0XM107728
GH0XG107727 1.5 Ensembl ENCODE dbSUPER 0.3 -44.4 -44430 5.3 HDGF PKNOX1 FOXA2 FEZF1 YY1 GLIS2 FOS KLF7 ZNF263 SP3 GC0XM107728 NCBP2L
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around NCBP2L on UCSC Golden Path with GeneCards custom track

Promoters for NCBP2L Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000247871 1401 2201 PKNOX1 ATF1 ZFP64 FEZF1 GLIS2 DEK ZNF263 SP3 REST GLIS1

Genomic Location for NCBP2L Gene

Chromosome:
X
Start:
107,774,899 bp from pter
End:
107,795,829 bp from pter
Size:
20,931 bases
Orientation:
Plus strand

Genomic View for NCBP2L Gene

Genes around NCBP2L on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NCBP2L Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NCBP2L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NCBP2L Gene

Proteins for NCBP2L Gene

  • Protein details for NCBP2L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6PVI3-NCB2L_HUMAN
    Recommended name:
    Nuclear cap-binding protein subunit 2-like
    Protein Accession:
    A6PVI3

    Protein attributes for NCBP2L Gene

    Size:
    153 amino acids
    Molecular mass:
    17685 Da
    Quaternary structure:
    No Data Available

neXtProt entry for NCBP2L Gene

Post-translational modifications for NCBP2L Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for NCBP2L Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for NCBP2L Gene

Domains & Families for NCBP2L Gene

Gene Families for NCBP2L Gene

Protein Domains for NCBP2L Gene

Suggested Antigen Peptide Sequences for NCBP2L Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6PVI3

UniProtKB/Swiss-Prot:

NCB2L_HUMAN :
  • Belongs to the RRM NCBP2 family.
Family:
  • Belongs to the RRM NCBP2 family.
genes like me logo Genes that share domains with NCBP2L: view

Function for NCBP2L Gene

Gene Ontology (GO) - Molecular Function for NCBP2L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000339 RNA cap binding IBA,IEA --
GO:0003676 nucleic acid binding IEA --
genes like me logo Genes that share ontologies with NCBP2L: view

Phenotypes for NCBP2L Gene

genes like me logo Genes that share phenotypes with NCBP2L: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NCBP2L Gene

Localization for NCBP2L Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for NCBP2L gene
Compartment Confidence
extracellular 3
cytosol 3
nucleus 1

Gene Ontology (GO) - Cellular Components for NCBP2L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005846 nuclear cap binding complex IEA,IBA --
genes like me logo Genes that share ontologies with NCBP2L: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for NCBP2L Gene

Pathways & Interactions for NCBP2L Gene

SuperPathways for NCBP2L Gene

No Data Available

Interacting Proteins for NCBP2L Gene

Selected Interacting proteins: A6PVI3-NCB2L_HUMAN for NCBP2L Gene via IID

Gene Ontology (GO) - Biological Process for NCBP2L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000398 mRNA splicing, via spliceosome IBA --
GO:0045292 mRNA cis splicing, via spliceosome IEA --
genes like me logo Genes that share ontologies with NCBP2L: view

No data available for Pathways by source and SIGNOR curated interactions for NCBP2L Gene

Drugs & Compounds for NCBP2L Gene

No Compound Related Data Available

Transcripts for NCBP2L Gene

mRNA/cDNA for NCBP2L Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for NCBP2L Gene

No ASD Table

Relevant External Links for NCBP2L Gene

GeneLoc Exon Structure for
NCBP2L
ECgene alternative splicing isoforms for
NCBP2L

Expression for NCBP2L Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for NCBP2L Gene

mRNA differential expression in normal tissues according to GTEx for NCBP2L Gene

This gene is overexpressed in Testis (x12.3) and Adrenal Gland (x9.1).

Protein differential expression in normal tissues from HIPED for NCBP2L Gene

This gene is overexpressed in Peripheral blood mononuclear cells (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for NCBP2L Gene



Protein tissue co-expression partners for NCBP2L Gene

NURSA nuclear receptor signaling pathways regulating expression of NCBP2L Gene:

NCBP2L
genes like me logo Genes that share expression patterns with NCBP2L: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for NCBP2L Gene

Orthologs for NCBP2L Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for NCBP2L Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia NCBP2L 35
  • 66 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 63 (a)
ManyToMany
-- 35
  • 63 (a)
ManyToMany
-- 35
  • 62 (a)
ManyToMany
-- 35
  • 60 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 44 (a)
OneToMany
chicken
(Gallus gallus)
Aves NCBP2 35
  • 56 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 56 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii ncbp2 35
  • 61 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta Cbp20 35
  • 55 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea ncbp-2 35
  • 47 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes CBC2 35
  • 31 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.10672 35
  • 47 (a)
OneToMany
Species where no ortholog for NCBP2L was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for NCBP2L Gene

ENSEMBL:
Gene Tree for NCBP2L (if available)
TreeFam:
Gene Tree for NCBP2L (if available)

Paralogs for NCBP2L Gene

Paralogs for NCBP2L Gene

(2) SIMAP similar genes for NCBP2L Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with NCBP2L: view

Variants for NCBP2L Gene

Sequence variations from dbSNP and Humsavar for NCBP2L Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs183595448 -- 107,781,656(+) CATCT(A/C/G)TCTAT intron-variant
rs185884038 -- 107,781,746(+) GATAT(A/C/T)TATAT intron-variant
rs191488997 -- 107,781,408(+) TCAAG(A/C/T)GATCC intron-variant
rs2295374 -- 107,794,199(+) CCATC(A/C/G/T)GCATG utr-variant-5-prime
rs5962885 -- 107,794,565(+) GATGT(A/C/T)GGTTT reference, synonymous-codon

Variation tolerance for NCBP2L Gene

Gene Damage Index Score: 2.95; 49.35% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for NCBP2L Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
NCBP2L

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for NCBP2L Gene

Disorders for NCBP2L Gene

No disorders were found for NCBP2L Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for NCBP2L Gene

Publications for NCBP2L Gene

  1. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3 64
  2. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 4 64

Products for NCBP2L Gene

Sources for NCBP2L Gene

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