NCBP2L Gene
protein-coding GIFtS: 26
GCID: GC0XP107037
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nuclear cap binding protein subunit 2-like
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Aliases
for NCBP2L gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Nuclear Cap Binding Protein Subunit 2-Like1 2 | | DJ820B18.11 |
Export aliases for NCBP2L gene to outside databasesPrevious GC identifers: GC0XP106825 GC0XU900756 |
Summaries
for NCBP2L gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for NCBP2L gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for NCBP2L
Other transcription factors
Search SABiosciences Chromatin IP Primers for NCBP2L
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NCBP2L |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xq22.3 Ensembl cytogenetic band: Xq22.3 HGNC cytogenetic band: Xq22.3NCBP2L Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XP107037: view genomic region
(about GC identifiers)
Start:
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107,037,451 bp from pter |
End:
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107,037,912 bp from pter |
Size:
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462 bases |
Orientation:
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plus strand |
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Proteins
for NCBP2L gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: NCB2L_HUMAN, A6PVI3 (See
protein sequence)Recommended Name: Nuclear cap-binding protein subunit 2-like Size: 153 amino acids; 17685 DaExplore the universe of human proteins at neXtProt for NCBP2L: NX_A6PVI3
NCBP2L Protein expression data from MOPED and PaxDb: About this image 
ENSEMBL proteins: ENSP00000361454
Human Recombinant Protein Products:
NCBP2L Antibody Products:
Assay Products for NCBP2L: |
Protein
Domains /
Families
for NCBP2L gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NCBP2L for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry A6PVI3ProtoNet protein and cluster: A6PVI3 UniProtKB/Swiss-Prot: NCB2L_HUMAN, A6PVI3Similarity: Belongs to the RRM NCBP2 familySimilarity: Contains 1 RRM (RNA recognition motif) domain |
Function
for NCBP2L gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
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Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000166 | nucleotide binding |
IEA | -- | | GO:0003676 | nucleic acid binding |
IEA | -- |
NCBP2L for ontologies About GeneDecksing
|
Pathways & Interactions
for NCBP2L gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NCBP2L
STRING Interaction
Network Preview (showing 5 interactants - click image to see 24)
5/24 Interacting proteins for NCBP2L (ENSP000003614544) via UniProtKB, MINT, STRING, and/or I2D (see all 24)About this table
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Drugs & Compounds
for NCBP2L gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for NCBP2L
Search CenterWatch for drugs/clinical trials and news about NCBP2L / NCB2L 
|
Transcripts
for NCBP2L gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
1 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000372379
1 AceView cDNA sequence: AI209084
GeneLoc Exon Structure
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Expression
for NCBP2L gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| NCBP2L expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See NCBP2L Protein Expression from SPIRE MOPED and PaxDB SABiosciences Custom PCR Arrays for NCBP2L
Primer
Products: |  | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat NCBP2L | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NCBP2L | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NCBP2L |
Orthologs
for NCBP2L gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of eukaryotes.
Orthologs for NCBP2L gene from 6/18 species (see all 18) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
NCBP2_CHICK6 |
Nuclear cap-binding protein subunit 2 |
59(a) |
1 ↔ 1 |
4(2426113-2428867) |
lizard
(Anolis carolinensis) |
Reptilia |
-- |
-- |
57(a) |
1 ↔ 1 |
GL343758.1(73652-77886) |
fruit fly
(Drosophila melanogaster) |
Insecta |
Cbp206 |
cap binding protein 20 |
58(a) |
1 → many |
3R(13990385-13991161) |
worm
(Caenorhabditis elegans) |
Secernentea |
ncbp-26 |
Nuclear cap-binding protein subunit 2 |
47(a) |
1 → many |
I(7642423-7643324) |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
CBP206 |
nuclear cap-binding protein subunit 2 |
30(a) |
1 → many |
5(17801814-17804130) |
rice
(Oryza sativa) |
Liliopsida |
-- |
RNA recognition motif containing protein, putative... |
33(a) |
1 → many |
2(24094209-24097624) |
ENSEMBL Gene Tree for NCBP2L (if available)
TreeFam Gene Tree for NCBP2L (if available) |
Paralogs
for NCBP2L gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for NCBP2L gene
- NCBP22
2 SIMAP similar genes for NCBP2L using alignment to 1 protein entry: NCB2L_HUMAN:NCBP2 DKFZp686G18222
NCBP2L for paralogs About GeneDecksing
|
Genomic Variants
for NCBP2L gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
Locus Specific Mutation Databases (LSDB): NCBP2L
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NCBP2L |
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Disorders
/ Diseases
for NCBP2L gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
NCBP2L for disorders About GeneDecksing
1  disease for NCBP2L: About MalaCardsmalaria
Export disorders for NCBP2L gene to outside databases
|
Publications
for NCBP2L gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for NCBP2L gene integrated from 9 sources:
(articles sorted by number of sources associating them with NCBP2L) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
- The DNA sequence of the human X chromosome. (PubMed id 15772651)2 Ross M.T.... Bentley D.R. (2005)
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External Searches for NCBP2L gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing NCBP2L gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing NCBP2L gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NCBP2L gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for NCBP2L | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for NCBP2L gene:
Search GeneIP for patents involving NCBP2L
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for NCBP2L gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NCBP2L | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NCBP2L | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NCBP2L | | | Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NCBP2L | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NCBP2L | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NCBP2L |
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 |  |  |  | |
| | | | Search Tocris compounds for NCBP2L |
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 | | | NCBP2L Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | Search ThermoFisher Antibodies for NCBP2L |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat NCBP2L |
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