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NCAPH Gene

protein-coding   GIFtS: 58
GCID: GC02P097001

Non-SMC Condensin I Complex, Subunit H

(Previous names: barren (Drosophila) homolog, barren homolog (Drosophila),...)
(Previous symbol: BRRN1)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Non-SMC Condensin I Complex, Subunit H1 2     Condensin Complex Subunit 22
BRRN11 2 3 5     BRRN3
Chromosome-Associated Protein H2 3     CAPH3
Barren (Drosophila) Homolog1     KIAA00743
Barren Homolog (Drosophila)1     Barren Homolog Protein 13
Barren Homolog 1 (Drosophila)1     hCAP-H3
CAP-H2     Non-SMC Condensin I Complex Subunit H3
Barren Homolog 12     XCAP-H Homolog3

External Ids:    HGNC: 11121   Entrez Gene: 233972   Ensembl: ENSG000001211527   OMIM: 6023325   UniProtKB: Q150033   

Export aliases for NCAPH gene to outside databases

Previous GC identifers: GC02P096365 GC02P090962


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for NCAPH Gene:
This gene encodes a member of the barr gene family and a regulatory subunit of the condensin complex. This complex
is required for the conversion of interphase chromatin into condensed chromosomes. The protein encoded by this
gene is associated with mitotic chromosomes, except during the early phase of chromosome condensation. During
interphase, the protein has a distinct punctate nucleolar localization. Alternatively spliced transcript variants
encoding different proteins have been described. (provided by RefSeq, Jul 2013)

GeneCards Summary for NCAPH Gene:
NCAPH (non-SMC condensin I complex, subunit H) is a protein-coding gene.

UniProtKB/Swiss-Prot: CND2_HUMAN, Q15003
Function: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin
into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into
relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the
presence of type II topoisomerases

Gene Wiki entry for NCAPH Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NT_005403.18  NC_018913.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the NCAPH gene promoter:
         AREB6   RP58   Tal-1   MyoD   FOXD1   c-Myb   Zic3   LCR-F1   E47   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNCAPH promoter sequence
   Search Chromatin IP Primers for NCAPH

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NCAPH


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q11.2   Ensembl cytogenetic band:  2q11.2   HGNC cytogenetic band: 2q11.2

NCAPH Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NCAPH gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P097001:  view genomic region     (about GC identifiers)

Start:
97,001,484 bp from pter      End:
97,041,274 bp from pter
Size:
39,791 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: CND2_HUMAN, Q15003 (See protein sequence)
Recommended Name: Condensin complex subunit 2  
Size: 741 amino acids; 82563 Da
Subunit: Component of the condensin complex, which contains the SMC2 and SMC4 heterodimer, and three non SMC
subunits that probably regulate the complex: NCAPH/BRRN1, NCAPD2/CAPD2 and NCAPG
Sequence caution: Sequence=BAA07556.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: Q8TB87

Explore the universe of human proteins at neXtProt for NCAPH: NX_Q15003

Explore proteomics data for NCAPH at MOPED

Post-translational modifications: 

  • Phosphorylated by CDK1. Its phosphorylation, as well as that of NCAPD2 and NCAPG subunits, activates the condensin
    complex and is required for chromosome condensation (By similarity)1
  • Ubiquitination2 at Lys41, Lys394, Lys424, Lys495, Lys648
  • Modification sites at PhosphoSitePlus

  • See NCAPH Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001268639.1  NP_001268640.1  NP_001268641.1  NP_056156.2  

    ENSEMBL proteins: 
     ENSP00000240423   ENSP00000400774   ENSP00000405237   ENSP00000401227   ENSP00000407308  
     ENSP00000415162  
    Reactome Protein details: Q15003

    NCAPH Human Recombinant Protein Products:

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    Novus Biologicals NCAPH Proteins
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    antibodies-online peptides for NCAPH

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR022816 Condensin_barren_su2

    Graphical View of Domain Structure for InterPro Entry Q15003

    ProtoNet protein and cluster: Q15003

    1 Blocks protein domain: IPB008418 Barren

    UniProtKB/Swiss-Prot: CND2_HUMAN, Q15003
    Similarity: Belongs to the CND2 (condensin subunit 2) family


    Find genes that share domains with NCAPH           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CND2_HUMAN, Q15003
    Function: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin
    into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into
    relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the
    presence of type II topoisomerases

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI17268547
         
    Find genes that share ontologies with NCAPH           About GenesLikeMe


    Phenotypes:
         4 MGI mutant phenotypes (inferred from 1 allele(MGI details for Ncaph):
     cellular  immune system  mortality/aging  vision/eye 

    Find genes that share phenotypes with NCAPH           About GenesLikeMe

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for NCAPH

    miRNA
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    miRTarBase miRNAs that target NCAPH:
    hsa-mir-92a-3p (MIRT049342), hsa-mir-192-5p (MIRT026338), hsa-mir-215-5p (MIRT024329), hsa-mir-484 (MIRT041751), hsa-mir-193b-3p (MIRT016393)

    Block miRNA regulation of human, mouse, rat NCAPH using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate NCAPH:
    hsa-miR-493* hsa-miR-3924 hsa-miR-628-5p
    SwitchGear 3'UTR luciferase reporter plasmidNCAPH 3' UTR sequence
    Inhib. RNA
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    Addgene plasmids for NCAPH 

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CND2_HUMAN, Q15003: Nucleus. Cytoplasm. Chromosome. Note=In interphase cells, the majority of the condensin
    complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation
    of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the
    condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the
    complex are phosphorylated by CDK1, leading to condensin's association with chromosome arms and to chromosome
    condensation. Dissociation from chromosomes is observed in late telophase
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytoskeleton4
    cytosol4

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000796condensin complex IDA11136719
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IDA--
    GO:0005829cytosol TAS--
    GO:0015630microtubule cytoskeleton IDA--

    Find genes that share ontologies with NCAPH           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for NCAPH About    
    See pathways by source

    SuperPathContained pathways About
    1Cell Cycle, Mitotic
    Cell Cycle, Mitotic0.90
    M Phase0.62
    Cell Cycle0.90
    2Mitotic Prometaphase
    Mitotic Prometaphase0.92
    Condensation of Prometaphase Chromosomes0.00
    3Cell cycle Chromosome condensation in prometaphase
    Cell cycle Chromosome condensation in prometaphase
    4Aurora B signaling
    Aurora B signaling


    Find genes that share SuperPaths with NCAPH           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for NCAPH
        Cell cycle Chromosome condensation in prometaphase

    1 BioSystems Pathway for NCAPH
        Aurora B signaling

    1 Reactome Pathway for NCAPH
        Condensation of Prometaphase Chromosomes


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NCAPH
    Interactions:

        Search GeneGlobe Interaction Network for NCAPH

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for NCAPH (Q150031, 2, 3 ENSP000002404234) via UniProtKB, MINT, STRING, and/or I2D (see all 852)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NCAPD2Q150211, 2, 3, ENSP000003250174EBI-1046410,EBI-1044041 MINT-7945693 MINT-4330136 MINT-4330190 MINT-4329880 MINT-4330147 MINT-7947479 I2D: score=1 STRING: ENSP00000325017
    SMC4Q9NTJ32, 3, ENSP000003413824MINT-7945693 MINT-4330064 MINT-7947479 I2D: score=1 STRING: ENSP00000341382
    CAPGP401212, 3, ENSP000002638674MINT-7945693 MINT-7947479 I2D: score=2 STRING: ENSP00000263867
    DDX3XO005711, 2EBI-1046410,EBI-353779 MINT-7945693 MINT-7947479
    AURKAO149652, 3MINT-7945693 I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000278mitotic cell cycle TAS--
    GO:0007076mitotic chromosome condensation IDA11136719

    Find genes that share ontologies with NCAPH           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NCAPH (CND2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for NCAPH gene (4 alternative transcripts): 
    NM_001281710.1  NM_001281711.1  NM_001281712.1  NM_015341.4  

    Unigene Cluster for NCAPH:

    Non-SMC condensin I complex, subunit H
    Hs.308045  [show with all ESTs]
    Unigene Representative Sequence: NM_015341
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000240423(uc010fhv.1 uc002svz.1 uc010yum.1 uc010yun.1)
    ENST00000427946 ENST00000477409(uc010fhu.1) ENST00000435975 ENST00000456906
    ENST00000455200 ENST00000435349
    miRNA
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    hsa-miR-493* hsa-miR-3924 hsa-miR-628-5p
    SwitchGear 3'UTR luciferase reporter plasmidNCAPH 3' UTR sequence
    Inhib. RNA
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      QuantiFast Probe-based Assays in human, mouse, rat NCAPH

    Additional mRNA sequence: 

    AK291053.1 AK299248.1 AK303725.1 AK308050.1 AK310649.1 BC024211.2 D38553.1 

    8 DOTS entries:

    DT.214623  DT.92432537  DT.86853974  DT.95345110  DT.100783319  DT.100783313  DT.95070228  DT.97822656 

    Selected AceView cDNA sequences (see all 207):

    BU163449 BQ689458 AI802280 BU157863 BQ691959 BM970326 BI861182 CR620375 
    AU131710 AI220961 BQ689107 BU185416 AL120899 BQ691965 BU163090 D38553 
    BX399369 BQ689571 BQ901040 BQ689336 BQ691275 BU196656 NM_015341 BQ882507 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for NCAPH (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c · 2d · 2e ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15 ^
    SP1:                    -                                                                                                                                       
    SP2:                    -     -                 -     -     -     -     -     -     -     -     -                                                               
    SP3:                    -     -                                                                                                                                 
    SP4:                    -     -     -                                                                                                                           
    SP5:                                                                                                                                            -               

    ExUns: 16 ^ 17 ^ 18a · 18b
    SP1:                        
    SP2:                        
    SP3:                        
    SP4:                        
    SP5:                        


    ECgene alternative splicing isoforms for NCAPH

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NCAPH expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    NCAPH Expression
    About this image


    NCAPH expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Neural Tube (Nervous System)
             Mesencephalic Ventricular Zone
     
     Pancreas (Endocrine System)
     
     Testis (Reproductive System)
    NCAPH Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NCAPH Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.308045

    UniProtKB/Swiss-Prot: CND2_HUMAN, Q15003
    Tissue specificity: Widely expressed at low level. Expressed in proliferating cells

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NCAPH

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for NCAPH gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ncaph1 , 5 non-SMC condensin I complex, subunit H1, 5 81.74(n)1
    79.81(a)1
      2 (61.76 cM)5
    2153871  NM_144818.31  NP_659067.21 
     1271038095 
    chicken
    (Gallus gallus)
    Aves NCAPH1 condensin complex subunit 2 65.96(n)
    61.19(a)
      425304  NM_001257332.1  NP_001244261.1 
    lizard
    (Anolis carolinensis)
    Reptilia NCAPH6
    non-SMC condensin I complex, subunit H
    57(a)
    1 ↔ 1
    GL343608.1(39752-69149)
    African clawed frog
    (Xenopus laevis)
    Amphibia brrn1-prov2 barren homolog (Drosophila) 77.5(n)    BC056095.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufc69h062 Transcribed sequence with weak similarity to protein more 76.95(n)    BM265158.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta barr1 barren 41.75(n)
    30.23(a)
      35287  NM_057758.4  NP_477106.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes BRN1(YBL097W)4 Subunit of the condensin complex; required for chromosome more   --   2(40831-43095) 852180  NP_009455.2 


    ENSEMBL Gene Tree for NCAPH (if available)
    TreeFam Gene Tree for NCAPH (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NCAPH (see all 817)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1808865751,2
    --96999576(+) CCTTCC/TAGGAC 1 -- us2k10--------
    rs119034611,2
    C,F,A,H--96999580(+) CCAGGA/GCCTTG 1 -- us2k122Minor allele frequency- G:0.33NS EA NA WA CSA 2351
    rs1491886031,2
    --96999595(+) ACGCTC/TAGAGG 1 -- us2k10--------
    rs1143880141,2
    F--96999658(+) GGGGAC/TAAGTG 1 -- us2k11Minor allele frequency- T:0.03WA 118
    rs1149335041,2
    C,F--96999713(+) CTGAGG/CGGGGG 1 -- us2k11Minor allele frequency- C:0.01WA 118
    rs1872168851,2
    --96999878(+) CTTGGG/TTGGCT 1 -- us2k10--------
    rs1920373021,2
    --96999915(+) GTGTCA/GACCTG 1 -- us2k10--------
    rs1423811161,2
    --97000017(+) GGTTTA/TCAGCC 1 -- us2k10--------
    rs1841675281,2
    --97000227(+) ACTTGC/GGAGGT 1 -- us2k10--------
    rs1513263161,2
    C--97000262(+) TGCCAC/TTGCAC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for NCAPH (97001484 - 97041274 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for NCAPH:    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv650e201CNV Deletion23290073
    nsv508155CNV Loss20534489
    nsv819311CNV Loss19587683
    nsv874677CNV Loss21882294
    nsv874679CNV Gain21882294
    nsv834305CNV Gain17160897
    esv5003CNV Complex18987735

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NCAPH
    DNA2.0 Custom Variant and Variant Library Synthesis for NCAPH

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 602332    OMIM disorders: --


    Find genes that share disorders with NCAPH           About GenesLikeMe


    Export disorders for NCAPH gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NCAPH gene, integrated from 10 sources (see all 35):
    (articles sorted by number of sources associating them with NCAPH)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. Cell cycle-dependent expression and nucleolar localization of hCAP- H. (PubMed id 11694586)1, 2 Cabello O.A.... Belmont J.W. (Mol. Biol. Cell 2001)
    3. Chromosome condensation by a human condensin complex in Xenopus egg extracts. (PubMed id 11136719)1, 2 Kimura K.... Hirano T. (J. Biol. Chem. 2001)
    4. Localization of BRRN1, the human homologue of Drosophila barr, to 2q11.2. (PubMed id 9417923)1, 3 Cabello O.A....Belmont J.W. (Genomics 1997)
    5. Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 7584044)1, 2 Nomura N.... Tabata S. (DNA Res. 1994)
    6. VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells. (PubMed id 23383273)1 Yu C.C....Chow L.P. (PLoS ONE 2013)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    8. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    9. A high-throughput approach for measuring temporal changes in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (Nat. Methods 2012)
    10. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 23397 HGNC: 1112 AceView: BRRN1 Ensembl:ENSG00000121152 euGenes: HUgn23397
    ECgene: NCAPH H-InvDB: NCAPH

    (According to HUGE)
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    HUGE: KIAA0074

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for NCAPH Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NCAPH gene:
    Search GeneIP for patents involving NCAPH

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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