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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NCAPH Gene

protein-coding   GIFtS: 55
GCID: GC02P097001

non-SMC condensin I complex, subunit H

(Previous names: barren (Drosophila) homolog, barren homolog (Drosophila),...)
(Previous symbol: BRRN1)
  Search for NCAPH
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Biological research products
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Aliases
for NCAPH gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Non-SMC Condensin I Complex, Subunit H1 2     Barren Homolog 1 (Drosophila)1
BRRN11 2 3 5     HCAP-H2
CAP-H1 2     Barren Homolog 12
HCAP-H2     Condensin Complex Subunit 22
Barren Homolog Protein 12 3     BRRN3
Chromosome-Associated Protein H2 3     CAPH3
XCAP-H Homolog2 3     KIAA00743
Barren (Drosophila) Homolog1     Non-SMC Condensin I Complex Subunit H3
Barren Homolog (Drosophila)1     

External Ids:    HGNC: 11121   Entrez Gene: 233972   Ensembl: ENSG000001211527   OMIM: 6023325   UniProtKB: Q150033   

Export aliases for NCAPH gene to outside databases

Previous GC identifers: GC02P096365 GC02P090962


Summaries
for NCAPH gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for NCAPH:
This gene encodes a member of the barr gene family and a regulatory subunit of the condensin complex. This complex is
required for the conversion of interphase chromatin into condensed chromosomes. The protein encoded by this gene is
associated with mitotic chromosomes, except during the early phase of chromosome condensation. During interphase, the
protein has a distinct punctate nucleolar localization. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: CND2_HUMAN, Q15003
Function: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into
mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in
the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II
topoisomerases

Gene Wiki entry for NCAPH


Genomic Views
for NCAPH gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.1  NT_022171.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NCAPH gene promoter:
         AREB6   RP58   Tal-1   MyoD   FOXD1   c-Myb   Zic3   LCR-F1   E47   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: NCAPH promoter sequence
   Search SABiosciences Chromatin IP Primers for NCAPH

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NCAPH


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q11.2   Ensembl cytogenetic band:  2q11.2   HGNC cytogenetic band: 2q11.2

NCAPH Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NCAPH gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P097001:  view genomic region     (about GC identifiers)

Start:
 97,001,484 bp from pter      End:
 97,041,274 bp from pter
Size:
 39,791 bases      Orientation:
 plus strand

Proteins
for NCAPH gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: CND2_HUMAN, Q15003 (See protein sequence)
Recommended Name: Condensin complex subunit 2  
Size: 741 amino acids; 82563 Da
Subunit: Component of the condensin complex, which contains the SMC2 and SMC4 heterodimer, and three non SMC subunits
that probably regulate the complex: NCAPH/BRRN1, NCAPD2/CAPD2 and NCAPG
Subcellular location: Nucleus. Cytoplasm. Chromosome. Note=In interphase cells, the majority of the condensin complex
is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the
complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin
complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are
phosphorylated by CDK1, leading to condensin's association with chromosome arms and to chromosome condensation.
Dissociation from chromosomes is observed in late telophase
Sequence caution: Sequence=BAA07556.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: Q8TB87

Explore the universe of human proteins at neXtProt for NCAPH: NX_Q15003

Post-translational modifications:

  • Phosphorylated by CDK1. Its phosphorylation, as well as that of NCAPD2 and NCAPG subunits, activates the condensin
    • complex and is required for chromosome condensation (By similarity)1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q15003

    • NCAPH Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_056156.2  
    ENSEMBL proteins: 
     ENSP00000240423   ENSP00000400774   ENSP00000405237   ENSP00000401227   ENSP00000407308  
     ENSP00000415162  
    Reactome Protein details: Q15003
    Human Recombinant Protein Products: 
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    Novus Biologicals NCAPH Proteins
    Novus Biologicals NCAPH Lysates
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    Uscn Proteins for NCAPH

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000796condensin complex IDA11136719
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IDA--
    GO:0015630microtubule cytoskeleton IDA--


    NCAPH for ontologies           About GeneDecksing



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    ThermoFisher Antibodies for NCAPH

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    Protein Domains /
    Families
    for NCAPH gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    NCAPH for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR022816 Condensin_barren_su2

    Graphical View of Domain Structure for InterPro Entry Q15003

    ProtoNet protein and cluster: Q15003

    1 Blocks protein family: IPB008418 Barren

    UniProtKB/Swiss-Prot: CND2_HUMAN, Q15003
    Similarity: Belongs to the CND2 (condensin subunit 2) family


    Function
    for NCAPH gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: CND2_HUMAN, Q15003
    Function: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into
    mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in
    the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II
    topoisomerases

    miRNA
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    3 QIAGEN miScript miRNA Assays for microRNAs that regulate NCAPH:
    hsa-miR-493* hsa-miR-3924 hsa-miR-628-5p
    SwitchGear 3'UTR luciferase reporter plasmid: NCAPH 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    In Situ Assay
    Products:       
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    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--


    NCAPH for ontologies           About GeneDecksing


    Animal Models:
         3 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Ncaph):
     immune system  mortality/aging  vision/eye 

    NCAPH for phenotypes           About GeneDecksing


    Pathways & Interactions
    for NCAPH gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Cell cycle Chromosome condensation in prometaphase
    		Cell cycle_Chromosome condensation in prometaphase1.00
    		Condensation of Prometaphase Chromosomes0.22
    		Cell cycle Chromosome condensation in prometaphase1.00
    2M Phase
    		M Phase1.00
    		Mitotic M-M/G1 phases0.88
    3Cell Cycle
    		Cell Cycle1.00
    		Cell Cycle, Mitotic0.84
    4Aurora B signaling
    		Aurora B signaling1.00
    5Resolution of Sister Chromatid Cohesion
    		Mitotic Prometaphase0.93

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for NCAPH
        Cell cycle Chromosome condensation in prometaphase


    1 GeneGo (Thomson Reuters) Pathway for NCAPH
        Cell cycle Chromosome condensation in prometaphase

    1 BioSystems Pathway for NCAPH 
        Aurora B signaling

    5/6        Reactome Pathways for NCAPH (see all 6)
        Mitotic Prometaphase
    Cell Cycle
    Condensation of Prometaphase Chromosomes
    M Phase
    Mitotic M-M/G1 phases



    NCAPH for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NCAPH

    STRING Interaction Network Preview (showing 5 interactants - click image to see 17)

    5/753 Interacting proteins for NCAPH (Q150031, 2, 3 ENSP000002404234) via UniProtKB, MINT, STRING, and/or I2D (see all 753)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NCAPD2Q150212, 3, ENSP000003250174MINT-7945693 MINT-4330136 MINT-4330190 MINT-4329880 MINT-4330147 MINT-7947479 I2D: score=1 STRING: ENSP00000325017
    SMC4Q9NTJ32, 3, ENSP000003413824MINT-7945693 MINT-4330064 MINT-7947479 I2D: score=1 STRING: ENSP00000341382
    CAPGP401212, 3, ENSP000002638674MINT-7945693 MINT-7947479 I2D: score=2 STRING: ENSP00000263867
    DDX3XO005711, 2EBI-1046410,EBI-353779 MINT-7945693 MINT-7947479
    AURKAO149652, 3MINT-7945693 I2D: score=1 
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007067mitosis ----
    GO:0007076mitotic chromosome condensation IDA11136719
    GO:0030261chromosome condensation ----
    GO:0051301cell division IEA--


    NCAPH for ontologies           About GeneDecksing



    Drugs & Compounds
    for NCAPH gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NCAPH
    Search CenterWatch for drugs/clinical trials and news about NCAPH / CND2 

    Transcripts
    for NCAPH gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for NCAPH gene: 
    NM_015341.3  

    Unigene Cluster for NCAPH:

    Non-SMC condensin I complex, subunit H
    Hs.308045  [show with all ESTs]
    Unigene Representative Sequence: NM_015341
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000240423(uc010fhv.1 uc002svz.1 uc010yum.1 uc010yun.1)
    ENST00000427946 ENST00000477409(uc010fhu.1) ENST00000435975 ENST00000456906
    ENST00000455200 ENST00000435349

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NCAPH
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate NCAPH:
    hsa-miR-493* hsa-miR-3924 hsa-miR-628-5p
    SwitchGear 3'UTR luciferase reporter plasmid: NCAPH 3' UTR sequence
    Inhib. RNA
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    OriGene shRNA RFP: NCAPH
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NCAPH
    Clone
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    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: NCAPH (NM_015341)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NCAPH
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NCAPH
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NCAPH

    Additional cDNA sequence: 

    AK291053.1 AK299248.1 AK303725.1 AK308050.1 AK310649.1 BC024211.2 D38553.1 

    8 DOTS entries:

    DT.214623  DT.92432537  DT.86853974  DT.95345110  DT.100783319  DT.100783313  DT.95070228  DT.97822656 

    24/207 AceView cDNA sequences (see all 207):

    BQ691168 AA808892 CA423478 BQ882507 BU163090 BQ689571 BM970326 BU157863 
    BQ691965 BQ689458 BQ961582 BU163449 BQ689336 BU185219 NM_015341 BM468688 
    AI802280 BQ690930 BQ687347 AW079231 BU180407 BF513300 BQ690837 BQ685302 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for NCAPH (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c · 2d · 2e ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15 ^
    SP1:                    -                                                                                                                                       
    SP2:                    -     -                 -     -     -     -     -     -     -     -     -                                                               
    SP3:                    -     -                                                                                                                                 
    SP4:                    -     -     -                                                                                                                           
    SP5:                                                                                                                                            -               

    ExUns: 16 ^ 17 ^ 18a · 18b
    SP1:                        
    SP2:                        
    SP3:                        
    SP4:                        
    SP5:                        


    ECgene alternative splicing isoforms for NCAPH

    Expression
    for NCAPH gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NCAPH expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    NCAPH expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Neural TubeMesencephalic Ventricular ZoneNeural Tube
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See NCAPH Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NCAPH

    SOURCE GeneReport for Unigene cluster: Hs.308045

    UniProtKB/Swiss-Prot: CND2_HUMAN, Q15003
    Tissue specificity: Widely expressed at low level. Expressed in proliferating cells

        SABiosciences Custom PCR Arrays for NCAPH
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    In Situ
    Assay Products:     
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    Orthologs
    for NCAPH gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for NCAPH gene from 9/29 species (see all 29)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Ncaph1 , 5 non-SMC condensin I complex, subunit H1, 5 81.74(n)1
    79.81(a)1    		   2 (61.76 cM)5
    2153871  NM_144818.31  NP_659067.21 
     1271038095 
    chicken
    (Gallus gallus)    		 Aves NCAPH6
    		 --
    		 62(a)
    		 1 ↔ 1
    		 22(145314-149770)
    lizard
    (Anolis carolinensis)    		 Reptilia NCAPH6
    		 --
    		 56(a)
    		 1 ↔ 1
    		 GL343608.1(44589-68061)
    African clawed frog
    (Xenopus laevis)    		 Amphibia brrn1-prov2 barren homolog (Drosophila) 77.5(n)    BC056095.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii wufc69h062 Transcribed sequence with weak similarity to protein more 76.95(n)    BM265158.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta barr6
    		 barren
    		 20(a)
    		 1 ↔ 1
    		 2L(20058163-20060975)
    baker's yeast
    (Saccharomyces cerevisiae)    		 Saccharomycetes BRN1(YBL097W)4
    BRN11    		 Subunit of the condensin complex; required for chromosome more4
    Brn1p1    		 41.75(n)1
    25.88(a)1    		   2(40831-43095)4
    8521801, 4  NP_009455.31  NP_009455.24 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT2G325901 condensin complex subunit 2 45.83(n)
    32.06(a)    		   817819  NM_128818.2  NP_180818.2 
    rice
    (Oryza sativa)    		 Liliopsida Os01g05328001 hypothetical protein 45.75(n)
    36.84(a)    		   4327806  NM_001049785.1  NP_001043250.2 


    ENSEMBL Gene Tree for NCAPH (if available)
    TreeFam Gene Tree for NCAPH (if available) 

    Paralogs
    for NCAPH gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    		  --

    Genomic Variants
    for NCAPH gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/678 NCBI SNPs in NCAPH are shown (see all 678)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 2 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1808865751,2
    		--96999576(+) CCTTCC/TAGGAC 1 -- us2k10--------
    rs119034611,2
    		C,F,A,H,--96999580(+) CCAGGA/GCCTTG 1 -- us2k122Minor allele frequency- G:0.33NS EA NA WA CSA 2351
    rs1491886031,2
    		--96999595(+) ACGCTC/TAGAGG 1 -- us2k10--------
    rs1143880141,2
    		F,--96999658(+) GGGGAC/TAAGTG 1 -- us2k11Minor allele frequency- T:0.03WA 118
    rs1149335041,2
    		--96999713(+) CTGAGG/CGGGGG 1 -- us2k11Minor allele frequency- C:0.01WA 118
    rs1872168851,2
    		--96999878(+) CTTGGG/TTGGCT 1 -- us2k10--------
    rs1920373021,2
    		--96999915(+) GTGTCA/GACCTG 1 -- us2k10--------
    rs1423811161,2
    		--97000017(+) GGTTTA/TCAGCC 1 -- us2k10--------
    rs1841675281,2
    		--97000227(+) ACTTGC/GGAGGT 1 -- us2k10--------
    rs1513263161,2
    		--97000262(+) TGCCAC/TTGCAC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for NCAPH (97001484 - 97041274 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for NCAPH
         1 CNV: 4300
         1 Indel: 59014

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NCAPH
    DNA2.0 Custom Variant and Variant Library Synthesis for NCAPH

    Disorders / Diseases
    for NCAPH gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    NCAPH for disorders           About MalaCards

    NCAPH for disorders           About GeneDecksing

    OMIM gene information: 602332    OMIM disorders: --


    Export disorders for NCAPH gene to outside databases

    Publications
    for NCAPH gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NCAPH gene, integrated from 9 sources (see all 31):
    (articles sorted by number of sources associating them with NCAPH)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. Cell cycle-dependent expression and nucleolar localization of hCAP- H. (PubMed id 11694586)1, 2 Cabello O.A.... Belmont J.W. (2001)
    3. Chromosome condensation by a human condensin complex in Xenopus egg extracts. (PubMed id 11136719)1, 2 Kimura K....Hirano T. (2001)
    4. Localization of BRRN1, the human homologue of Drosophila barr, to 2q11.2. (PubMed id 9417923)1, 3 Cabello O.A....Belmont J.W. (1997)
    5. Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 7584044)1, 2 Nomura N....Tabata S. (1994)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    7. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    8. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    9. Condensin association with histone H2A shapes mitotic chromosomes. (PubMed id 21633354)1 Tada K....Watanabe Y. (2011)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)

    External Searches for NCAPH gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing NCAPH gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 23397 HGNC: 1112 AceView: BRRN1 Ensembl:ENSG00000121152 euGenes: HUgn23397
    ECgene: NCAPH H-InvDB: NCAPH

    Other Databases showing NCAPH gene

    (According to HUGE)
    About This Section
    HUGE: KIAA0074

    Specialized Databases showing NCAPH gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NCAPH Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for NCAPH gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for NCAPH gene:
    Search GeneIP for patents involving NCAPH

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
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    About This Section

     
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