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NCAPG2 Gene

protein-coding   GIFtS: 52
GCID: GC07M158424

Non-SMC Condensin II Complex, Subunit G2

(Previous name: leucine zipper protein 5)
(Previous symbol: LUZP5)
  Search for NCAPG2
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Non-SMC Condensin II Complex, Subunit G21 2     CAPG22 5
Leucine Zipper Protein 51 2 3     MTB2 5
LUZP51 2 3     Condensin-2 Complex Subunit G22
Chromosome-Associated Protein G22 3     More Than Blood Homolog2
CAP-G22 3     Non-SMC Condensin II Complex Subunit G23
hCAP-G22 3     

External Ids:    HGNC: 219041   Entrez Gene: 548922   Ensembl: ENSG000001469187   OMIM: 6085325   UniProtKB: Q86XI23   

Export aliases for NCAPG2 gene to outside databases

Previous GC identifers: GC07M158116 GC07M152163


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for NCAPG2 Gene:
This gene encodes a protein that belongs to the Condensin2nSMC family of proteins. The encoded protein is a
regulatory subunit of the condensin II complex which, along with the condensin I complex, plays a role in
chromosome assembly and segregation during mitosis. A similar protein in mouse is required for early development
of the embryo. Alternate splicing results in multiple transcript variants. (provided by RefSeq, Aug 2013)

GeneCards Summary for NCAPG2 Gene:
NCAPG2 (non-SMC condensin II complex, subunit G2) is a protein-coding gene. GO annotations related to this gene include methylated histone residue binding.

UniProtKB/Swiss-Prot: CNDG2_HUMAN, Q86XI2
Function: Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome
architecture and is involved in physical rigidity of the chromatid axis

Gene Wiki entry for NCAPG2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000007.13  NT_007933.16  NC_018918.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the NCAPG2 gene promoter:
         STAT1   Sp1   ATF-2   STAT1beta   STAT1alpha   Evi-1   FOXL1   STAT2   STAT3   MRF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 4): NCAPG2 promoter sequence
   Search Chromatin IP Primers for NCAPG2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NCAPG2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q36.3   Ensembl cytogenetic band:  7q36.3   HGNC cytogenetic band: 7q36.3

NCAPG2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NCAPG2 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M158424:  view genomic region     (about GC identifiers)

Start:
158,424,003 bp from pter      End:
158,497,520 bp from pter
Size:
73,518 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 157,628,658-157,701,735     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CNDG2_HUMAN, Q86XI2 (See protein sequence)
Recommended Name: Condensin-2 complex subunit G2  
Size: 1143 amino acids; 130960 Da
Subunit: Component of the condensin-2 complex, which contains the SMC2 and SMC4 heterodimer, and 3 non SMC
subunits that probably regulate the complex: NCAPH2, NCAPD3 and NCAPG2
Sequence caution: Sequence=AAH20560.1; Type=Erroneous initiation; Sequence=BAB14219.1; Type=Erroneous initiation;
Sequence=BAB14534.1; Type=Erroneous initiation;
Secondary accessions: A4D228 Q7Z3J9 Q8WUG8 Q9BRX6 Q9H8S2 Q9H9K6
Alternative splicing: 2 isoforms:  Q86XI2-1   Q86XI2-2   

Explore the universe of human proteins at neXtProt for NCAPG2: NX_Q86XI2

Explore proteomics data for NCAPG2 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys45, Lys139, Lys178, Lys332, Lys402, Lys406, Lys422, Lys451, Lys474, Lys496,
                                 Lys650, Lys660, Lys796, Lys809, Lys1025, Lys1054
  • Modification sites at PhosphoSitePlus

  • See NCAPG2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001268861.1  NP_001268862.1  NP_060230.5  

    ENSEMBL proteins: 
     ENSP00000414337   ENSP00000348657   ENSP00000386569   ENSP00000408080   ENSP00000387007  
     ENSP00000275830   ENSP00000442337   ENSP00000388326  
    Reactome Protein details: Q86XI2

    NCAPG2 Human Recombinant Protein Products:

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    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR011989 ARM-like
     IPR024741 Condensin2_G2
     IPR016024 ARM-type_fold

    Graphical View of Domain Structure for InterPro Entry Q86XI2

    ProtoNet protein and cluster: Q86XI2

    UniProtKB/Swiss-Prot: CNDG2_HUMAN, Q86XI2
    Similarity: Contains 1 HEAT repeat


    Find genes that share domains with NCAPG2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CNDG2_HUMAN, Q86XI2
    Function: Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome
    architecture and is involved in physical rigidity of the chromatid axis

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005488binding ----
    GO:0005515protein binding IPI17268547
    GO:0035064methylated histone residue binding IDA--
         
    Find genes that share ontologies with NCAPG2           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for NCAPG2:
     Increased G2M DNA content 

         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Ncapg2):
     cellular  embryogenesis  mortality/aging 

    Find genes that share phenotypes with NCAPG2           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Ncapg2tm1Jdc for NCAPG2

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NCAPG2
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NCAPG2

    miRNA
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    miRTarBase miRNAs that target NCAPG2:
    hsa-mir-1260b (MIRT052754), hsa-let-7b-5p (MIRT005219), hsa-mir-26b-5p (MIRT030328)

    Block miRNA regulation of human, mouse, rat NCAPG2 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate NCAPG2:
    hsa-miR-656
    SwitchGear 3'UTR luciferase reporter plasmidNCAPG2 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat NCAPG2

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector: NCAPG2 (NM_017760)
    Browse Sino Biological Human cDNA Clones
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NCAPG2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CNDG2_HUMAN, Q86XI2: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    plasma membrane3
    cytosol1
    endoplasmic reticulum1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005654nucleoplasm TAS--
    GO:0005730NOT nucleolus IDA--

    Find genes that share ontologies with NCAPG2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for NCAPG2 About    
    See pathways by source

    SuperPathContained pathways About
    1Cell Cycle, Mitotic
    Cell Cycle, Mitotic0.90
    M Phase0.62
    Cell Cycle0.90
    2RNA Polymerase I Promoter Opening
    Condensation of Prophase Chromosomes0.78
    Mitotic Prophase0.56
    3Cell cycle Chromosome condensation in prometaphase
    Cell cycle Chromosome condensation in prometaphase


    Find genes that share SuperPaths with NCAPG2           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for NCAPG2
        Cell cycle Chromosome condensation in prometaphase

    1 Reactome Pathway for NCAPG2
        Condensation of Prophase Chromosomes


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NCAPG2
    Interactions:

        Search GeneGlobe Interaction Network for NCAPG2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    Selected Interacting proteins for NCAPG2 (Q86XI21, 2, 3 ENSP000003486574) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NCAPH2Q6IBW41, 2, 3, ENSP000004100884EBI-1047404,EBI-2548296 MINT-4329926 MINT-4330086 I2D: score=1 STRING: ENSP00000410088
    SMC2O953472, 3, ENSP000002863984MINT-4329970 I2D: score=1 STRING: ENSP00000286398
    TAL1P175423, ENSP000002943394I2D: score=2 STRING: ENSP00000294339
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    NEK6Q9HC983, ENSP000003627024I2D: score=1 STRING: ENSP00000362702
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000278mitotic cell cycle TAS--
    GO:0001833inner cell mass cell proliferation IEA--
    GO:0007067mitosis IEA--
    GO:0030261chromosome condensation IEA--

    Find genes that share ontologies with NCAPG2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NCAPG2 (CNDG2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for NCAPG2 gene (3 alternative transcripts): 
    NM_001281932.1  NM_001281933.1  NM_017760.6  

    Unigene Cluster for NCAPG2:

    Non-SMC condensin II complex, subunit G2
    Hs.18616  [show with all ESTs]
    Unigene Representative Sequence: BX537845
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000432615(uc003wnw.1) ENST00000356309(uc010lqu.1 uc003wnv.1)
    ENST00000409423(uc003wnx.1) ENST00000441982 ENST00000467785 ENST00000409339(uc011kwd.1 uc011kwe.1)
    ENST00000474940 ENST00000475918 ENST00000491792 ENST00000472591 ENST00000479022
    ENST00000275830 ENST00000541468(uc011kwc.1) ENST00000449727
    miRNA
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    Block miRNA regulation of human, mouse, rat NCAPG2 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate NCAPG2:
    hsa-miR-656
    SwitchGear 3'UTR luciferase reporter plasmidNCAPG2 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for NCAPG2
    Predesigned siRNA for gene silencing in human, mouse, rat NCAPG2
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    GenScript: all cDNA clones in your preferred vector: NCAPG2 (NM_017760)
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      QuantiTect SYBR Green Assays in human, mouse, rat NCAPG2
      QuantiFast Probe-based Assays in human, mouse, rat NCAPG2

    Additional mRNA sequence: 

    AK000318.1 AK022744.1 AK023347.1 AK092008.1 AK295057.1 AK301901.1 AK315699.1 BC005878.2 
    BC020560.1 BC028618.1 BC043404.1 BX537845.1 

    11 DOTS entries:

    DT.100815400  DT.409002  DT.100815399  DT.92437242  DT.95374146  DT.91675997  DT.100815392  DT.40109088 
    DT.121065183  DT.100815391  DT.121065184 

    Selected AceView cDNA sequences (see all 146):

    BX643469 AL536911 BM761189 BM844054 BQ010722 BM844351 AK022744 BQ641868 
    CB152157 BM541414 AI478936 BE893730 BE875296 BM917073 BC020560 BI086346 
    BM987954 AK023347 AK000318 BM561852 CR594919 BF331660 BE869313 BC043404 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for NCAPG2 (see all 10)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19a · 19b ^ 20a · 20b ^ 21 ^
    SP1:                          -           -                                                                                   -     -     -                     
    SP2:                    -     -           -                                                                                   -     -     -                     
    SP3:                    -     -           -                                                                                   -     -     -                     
    SP4:                                      -                                                                                                                     
    SP5:                                                                                                                                -                           

    ExUns: 22a · 22b · 22c ^ 23 ^ 24 ^ 25 ^ 26 ^ 27 ^ 28 ^ 29 ^ 30 ^ 31 ^ 32 ^ 33 ^ 34 ^ 35
    SP1:                                                                                      -         
    SP2:                                                                                                
    SP3:                                                                                      -         
    SP4:                                                                                                
    SP5:                                                                                                


    ECgene alternative splicing isoforms for NCAPG2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NCAPG2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATTCCAAGAA
    NCAPG2 Expression
    About this image

    NCAPG2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NCAPG2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.18616
        Custom PCR Arrays for NCAPG2
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NCAPG2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for NCAPG2 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ncapg21 , 5 non-SMC condensin II complex, subunit G21, 5 83.11(n)1
    81.27(a)1
      12 (62.65 cM)5
    760441  NM_133762.31  NP_598523.31 
     1164054025 
    chicken
    (Gallus gallus)
    Aves LOC1008595571 condensin-2 complex subunit G2-like 67.37(n)
    62.01(a)
      100859557  XM_003640678.2  XP_003640726.1 
    lizard
    (Anolis carolinensis)
    Reptilia NCAPG26
    non-SMC condensin II complex, subunit G2
    57(a)
    1 ↔ 1
    6(7299032-7329341)
    African clawed frog
    (Xenopus laevis)
    Amphibia BJ059476.12   -- 76.78(n)    BJ059476.1 
    zebrafish
    (Danio rerio)
    Actinopterygii ncapg21 non-SMC condensin II complex, subunit G2 54.5(n)
    46.86(a)
      100037337  NM_001089492.2  NP_001082961.2 
    worm
    (Caenorhabditis elegans)
    Secernentea capg-26
    Protein CAPG-2 (capg-2) mRNA, complete cds
    19(a)
    1 ↔ 1
    V(12271884-12275663) WBGene00010093


    ENSEMBL Gene Tree for NCAPG2 (if available)
    TreeFam Gene Tree for NCAPG2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NCAPG2 (see all 1773)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1492905891,2
    C--158423608(+) GAGGC-/AAAACAT 1 -- int10--------
    rs1877863091,2
    --158423614(+) AACATC/GAAGGT 1 -- int10--------
    rs737304701,2
    C,F--158423664(+) CACTCA/CGGGAG 1 -- int12Minor allele frequency- C:0.06WA 120
    rs1927234381,2
    --158423680(+) CAGCAC/TCTCAC 1 -- int10--------
    rs1448269831,2
    --158423800(+) TTCCTG/TAGTAG 1 -- int10--------
    rs1482492921,2
    --158423812(+) TGGGAC/TTACAG 1 -- int10--------
    rs2004911191,2
    --158423816(+) ATTAC-/AGGCAT 1 -- int10--------
    rs1413112461,2
    --158423937(+) CCTCCC/GAAAGT 1 -- int10--------
    rs1508042031,2
    C--158423995(+) AAATAA/CACAAA 1 -- int10--------
    rs1841619731,2
    --158424023(+) TTATTA/CCTCAT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for NCAPG2 (158424003 - 158497520 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for NCAPG2 (see all 21):    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv1217e201CNV Deletion23290073
    esv2736029CNV Deletion23290073
    esv2736018CNV Deletion23290073
    esv2229751CNV Deletion18987734
    esv2736026CNV Deletion23290073
    esv993130CNV Deletion20482838
    esv2736017CNV Deletion23290073
    dgv1216e201CNV Deletion23290073
    esv2736019CNV Deletion23290073
    esv2736021CNV Deletion23290073

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NCAPG2
    DNA2.0 Custom Variant and Variant Library Synthesis for NCAPG2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 608532    OMIM disorders: --


    Find genes that share disorders with NCAPG2           About GenesLikeMe


    Export disorders for NCAPG2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NCAPG2 gene, integrated from 10 sources (see all 26):
    (articles sorted by number of sources associating them with NCAPG2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Differential contributions of condensin I and condensin II to mitotic chromosome architecture in vertebrate cells. (PubMed id 14532007)1, 2, 3 Ono T.... Hirano T. (Cell 2003)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (Science 2003)
    5. Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics. (PubMed id 23956138)1 Foerster S....Ritter C.A. (Proteomics 2013)
    6. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    7. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    9. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    10. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 54892 HGNC: 21904 AceView: MTB Ensembl:ENSG00000146918 euGenes: HUgn54892
    ECgene: NCAPG2 H-InvDB: NCAPG2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for NCAPG2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NCAPG2 gene:
    Search GeneIP for patents involving NCAPG2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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