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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NCAPG Gene

protein-coding   GIFtS: 61
GCID: GC04P017812

non-SMC condensin I complex, subunit G
 Explore 7 diseases affiliated with
NCAPG via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for NCAPG    

Aliases
for NCAPG gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Non-SMC Condensin I Complex, Subunit G1 2     FLJ124501
CAPG2 3 5     CHCG2
HCAP-G1     NY-MEL-32
Chromosome-Associated Protein G2 3     Chromosome Condensation Protein G2
Condensin Subunit CAP-G2 3     Condensin Complex Subunit 32
Melanoma Antigen NY-MEL-32 3     NYMEL33
XCAP-G Homolog2 3     Non-SMC Condensin I Complex Subunit G3
CAP-G1     

External Ids:    HGNC: 243041   Entrez Gene: 641512   Ensembl: ENSG000001098057   OMIM: 6062805   UniProtKB: Q9BPX33   

Export aliases for NCAPG gene to outside databases

Previous GC identifers: GC04P017421 GC04P017167


Summaries
for NCAPG gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for NCAPG:
This gene encodes a subunit of the condensin complex, which is responsible for the condensation and stabilization of
chromosomes during mitosis and meiosis. Phosphorylation of the encoded protein activates the condensin complex. There
are pseudogenes for this gene on chromosomes 8 and 15. Alternative splicing results in multiple transcript variants.
(provided by RefSeq, Aug 2012)

UniProtKB/Swiss-Prot: CND3_HUMAN, Q9BPX3
Function: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into
mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in
the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II
topoisomerases

Gene Wiki entry for NCAPG


Genomic Views
for NCAPG gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NC_018915.1  NT_006316.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NCAPG gene promoter:
         HSF1 (long)   Tal-1beta   GATA-2   GATA-1   E47   FOXL1   HSF1short   Pax-4a   Hlf   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: NCAPG promoter sequence
   Search SABiosciences Chromatin IP Primers for NCAPG

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NCAPG


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4p15.33   Ensembl cytogenetic band:  4p15.31   HGNC cytogenetic band: 4p15.32

NCAPG Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NCAPG gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P017812:  view genomic region     (about GC identifiers)

Start:
 17,812,525 bp from pter      End:
 17,846,488 bp from pter
Size:
 33,964 bases      Orientation:
 plus strand

Proteins
for NCAPG gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: CND3_HUMAN, Q9BPX3 (See protein sequence)
Recommended Name: Condensin complex subunit 3  
Size: 1015 amino acids; 114334 Da
Subunit: Component of the condensin complex, which contains the SMC2 and SMC4 heterodimer, and three non SMC subunits
that probably regulate the complex: NCAPH/BRRN1, NCAPD2/CAPD2 and NCAPG
Subcellular location: Nucleus. Cytoplasm. Chromosome. Note=In interphase cells, the majority of the condensin complex
is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the
complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin
complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are
phosphorylated by CDK1, leading to condensin's association with chromosome arms and to chromosome condensation.
Dissociation from chromosomes is observed in late telophase
Miscellaneous: Overexpressed in some cancer lines and some tumor cells
Sequence caution: Sequence=AAH00827.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAB14429.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAB55165.1;
Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: Q3MJE0 Q96SV9 Q9BUR3 Q9BVY1 Q9H914 Q9H9Z6 Q9HBI9

Explore the universe of human proteins at neXtProt for NCAPG: NX_Q9BPX3

Post-translational modifications:

  • Phosphorylated by CDK1. Its phosphorylation, as well as that of NCAPD2 and NCAPH subunits, activates the condensin
    • complex and is required for chromosome condensation (By similarity)1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9BPX3

    • NCAPG Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_071741.2  
    ENSEMBL proteins: 
     ENSP00000251496   ENSP00000423042   ENSP00000425625  
    Reactome Protein details: Q9BPX3
    Human Recombinant Protein Products: 
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    Novus Biologicals NCAPG Protein
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    Uscn Proteins for NCAPG

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000796condensin complex IDA11136719
    GO:0005634nucleus NAS10910072
    GO:0005737cytoplasm IDA--
    GO:0005813centrosome IDA--
    GO:0015629actin cytoskeleton IDA--


    NCAPG for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for NCAPG

    Protein Domains /
    Families
    for NCAPG gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    NCAPG for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR011989 ARM-like
     IPR027165 CND3
     IPR025977 Cnd3_C
     IPR016024 ARM-type_fold

    Graphical View of Domain Structure for InterPro Entry Q9BPX3

    ProtoNet protein and cluster: Q9BPX3

    1 Blocks protein family: IPB000357 HEAT repeat

    UniProtKB/Swiss-Prot: CND3_HUMAN, Q9BPX3
    Similarity: Belongs to the CND3 (condensin subunit 3) family
    Similarity: Contains 10 HEAT repeats


    Function
    for NCAPG gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: CND3_HUMAN, Q9BPX3
    Function: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into
    mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in
    the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II
    topoisomerases

    miRNA
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    hsa-mir-21 (MIRT000171)

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    Browse MicroRNA Expression Plasmids
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    8/10 QIAGEN miScript miRNA Assays for microRNAs that regulate NCAPG (see all 10):
    hsa-miR-548d-3p hsa-miR-1258 hsa-miR-944 hsa-miR-3907 hsa-miR-105 hsa-miR-182* hsa-miR-659 hsa-miR-3168
    SwitchGear 3'UTR luciferase reporter plasmid: NCAPG 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NCAPG (see all 4)
    OriGene shRNA RFP: NCAPG
    OriGene siRNA: NCAPG
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NCAPG

    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI12138188


    NCAPG for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for NCAPG:
     Synthetic lethal with Ras 


    Pathways & Interactions
    for NCAPG gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Cell cycle Chromosome condensation in prometaphase
    		Cell cycle_Chromosome condensation in prometaphase1.00
    		Condensation of Prometaphase Chromosomes0.22
    		Cell cycle Chromosome condensation in prometaphase1.00
    2M Phase
    		M Phase1.00
    		Mitotic M-M/G1 phases0.88
    3Cell Cycle
    		Cell Cycle1.00
    		Cell Cycle, Mitotic0.84
    4Aurora B signaling
    		Aurora B signaling1.00
    5Resolution of Sister Chromatid Cohesion
    		Mitotic Prometaphase0.93

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for NCAPG
        Cell cycle Chromosome condensation in prometaphase


    1 GeneGo (Thomson Reuters) Pathway for NCAPG
        Cell cycle Chromosome condensation in prometaphase

    1 BioSystems Pathway for NCAPG 
        Aurora B signaling

    5/6        Reactome Pathways for NCAPG (see all 6)
        Mitotic Prometaphase
    Cell Cycle
    Condensation of Prometaphase Chromosomes
    M Phase
    Mitotic M-M/G1 phases



    NCAPG for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NCAPG

    STRING Interaction Network Preview (showing 5 interactants - click image to see 21)

    5/572 Interacting proteins for NCAPG (Q9BPX32, 3 ENSP000002514964) via UniProtKB, MINT, STRING, and/or I2D (see all 572)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SMC2O953472, 3, ENSP000002863984MINT-7945693 MINT-4329981 I2D: score=1 STRING: ENSP00000286398
    POLD1P283402, 3MINT-7945693 I2D: score=1 
    UBA5Q9GZZ92, 3MINT-7945693 I2D: score=1 
    NCAPD2Q150212, 3, ENSP000003250174MINT-7945693 MINT-4329892 MINT-4330111 I2D: score=1 STRING: ENSP00000325017
    NCAPHQ150032, 3, ENSP000002404234MINT-4330165 MINT-7945693 MINT-4330125 I2D: score=1 STRING: ENSP00000240423
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007076mitotic chromosome condensation NAS10910072
    GO:0051301cell division IEA--


    NCAPG for ontologies           About GeneDecksing



    Drugs & Compounds
    for NCAPG gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NCAPG
    Search CenterWatch for drugs/clinical trials and news about NCAPG / CND3 

    Transcripts
    for NCAPG gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for NCAPG gene: 
    NM_022346.4  

    Unigene Cluster for NCAPG:

    Non-SMC condensin I complex, subunit G
    Hs.567567  [show with all ESTs]
    Unigene Representative Sequence: NM_022346
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000251496(uc003gpp.3 uc011bxj.2) ENST00000514176 ENST00000513226
    ENST00000509719 ENST00000510063

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NCAPG
    8/10 QIAGEN miScript miRNA Assays for microRNAs that regulate NCAPG (see all 10):
    hsa-miR-548d-3p hsa-miR-1258 hsa-miR-944 hsa-miR-3907 hsa-miR-105 hsa-miR-182* hsa-miR-659 hsa-miR-3168
    SwitchGear 3'UTR luciferase reporter plasmid: NCAPG 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NCAPG (see all 4)
    OriGene shRNA RFP: NCAPG
    OriGene siRNA: NCAPG
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NCAPG
    Clone
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    GenScript: all cDNA clones in your preferred vector: NCAPG (NM_017760)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NCAPG
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NCAPG 
    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NCAPG
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NCAPG

    Additional cDNA sequence: 

    AB013299.1 AF235023.1 AF331796.1 AK022512.1 AK023147.1 AK027511.1 BC000827.1 BC002337.2 
    BC068467.1 BC101476.1 BC143383.1 NR_073124.1 

    9 DOTS entries:

    DT.106739  DT.99947850  DT.100818993  DT.427779  DT.121231908  DT.121231951  DT.121231954  DT.95173678 
    DT.102827054 

    24/201 AceView cDNA sequences (see all 201):

    BE278549 AA640134 AU125409 BM756908 BF034032 AW468663 BM874416 CA423579 
    AF331796 BM767268 BI253340 BQ951725 CA335931 AU119856 BF795312 NM_022346 
    BM987728 CB127449 AI954042 BC002337 BU509786 BE542926 BM873985 AI341607 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for NCAPG    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18a · 18b ^ 19 ^ 20 ^
    SP1:                          -                 -                       -                                                                       -               
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 21
    SP1:      
    SP2:      
    SP3:      
    SP4:      
    SP5:      


    ECgene alternative splicing isoforms for NCAPG

    Expression
    for NCAPG gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NCAPG expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AAGTTCCAGA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    NCAPG expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    10/11 LifeMap In Vivo Development Anatomical Compartments/Cells (see all 11) 
    Tissue Anatomical Compartment CellCategory (developmental path)
    BrainBlood Brain BarrierEndothelial CellsBlood Brain Barrier, Endothelium
    BrainBlood Brain BarrierPostnatal Endothelial CellsBlood Brain Barrier, Endothelium
    HeartMyocardiumCardiac FibroblastsEpicardium
    KidneyS-shaped BodyKidney Endothelial CellsEndothelium
    BrainMedulla OblongataBrain
    KidneyMetanephrosKidney
    Neural TubeDiencephalic Ventricular ZoneNeural Tube
    Neural TubeMesencephalic Ventricular ZoneNeural Tube
    Neural TubeMetencephalonNeural Tube
    Neural TubeTelencephalonNeural Tube
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 2 LifeMap Cells 
    NameCategory
    PureStem™ progenitor E44 (Embryonic Progenitor Cell)
    PureStem™ progenitor F15 (Embryonic Progenitor Cell)

    See NCAPG Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NCAPG

    SOURCE GeneReport for Unigene cluster: Hs.567567

    UniProtKB/Swiss-Prot: CND3_HUMAN, Q9BPX3
    Tissue specificity: Highly expressed in testis

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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NCAPG

    Orthologs
    for NCAPG gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for NCAPG gene from 9/32 species (see all 32)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Ncapg1 , 5 non-SMC condensin I complex, subunit G1, 5 86.45(n)1
    83.07(a)1    		   5 (25.23 cM)5
    543921  NM_019438.11  NP_062311.11 
     456699225 
    chicken
    (Gallus gallus)    		 Aves NCAPG1 non-SMC condensin I complex, subunit G 70.76(n)
    65.41(a)    		   422822  XM_420769.3  XP_420769.3 
    lizard
    (Anolis carolinensis)    		 Reptilia NCAPG6
    		 --
    		 61(a)
    		 1 ↔ 1
    		 5(76900992-76930891)
    African clawed frog
    (Xenopus laevis)    		 Amphibia LOC3980882 chromosome condensation protein XCAP-G 73.93(n)    BC041184.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii ncapg1 non-SMC condensin I complex, subunit G 58.94(n)
    53.2(a)    		   492707  XM_001921332.2  XP_001921367.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta Cap-G1 CG34438-PF 40.99(n)
    26.56(a)    		   36440  NM_001169664.1  NP_001163135.1 
    baker's yeast
    (Saccharomyces cerevisiae)    		 Saccharomycetes YCG1(YDR325W)4
    YCG11    		 Subunit of the condensin complex; required for establishment more4
    Ycg1p1    		 43.62(n)1
    26.64(a)1    		   4(1117126-1120233)4
    8519251, 4  NP_010612.21, 4 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons EMB26561 condensin complex subunit 3 42.4(n)
    28.6(a)    		   833741  NM_123122.3  NP_198579.2 
    rice
    (Oryza sativa)    		 Liliopsida Os06g02561001 hypothetical protein   --   9269856  NM_001187770.1  NP_001174699.1 


    ENSEMBL Gene Tree for NCAPG (if available)
    TreeFam Gene Tree for NCAPG (if available) 

    Paralogs
    for NCAPG gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NCAPG gene

    NCAPG for paralogs           About GeneDecksing


    3 Pseudogenes.org Pseudogenes for NCAPG
    PGOHUM00000247036 PGOHUM00000235163 PGOHUM00000249496


    Genomic Variants
    for NCAPG gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 3 variations for NCAPG
         2 CNVs: 98637 98638
         1 Indel: 59184
    SABiosciences Cancer Mutation PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NCAPG
    DNA2.0 Custom Variant and Variant Library Synthesis for NCAPG

    Disorders / Diseases
    for NCAPG gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    NCAPG for disorders           About GeneDecksing

    OMIM gene information: 606280    OMIM disorders: --

    7 diseases for NCAPG:    About MalaCards
    melanoma    croup    nasopharyngitis    pancreatic cancer
    pancreatitis    hypoxia    carcinoma

    1 disease from the University of Copenhagen DISEASES database for NCAPG:
    Croup
    Human Genome Epidemiology (HuGE) Navigator: NCAPG (1 document)

    Export disorders for NCAPG gene to outside databases

    Publications
    for NCAPG gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NCAPG gene, integrated from 9 sources (see all 45):
    (articles sorted by number of sources associating them with NCAPG)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Serological cloning of a melanocyte rab guanosine 5'-triphosphate- binding protein and a chromosome condensation protein from a melanoma complementary DNA library. (PubMed id 10910072)1, 2, 3, 9 Jaeger D.... Chen Y.-T. (2000)
    2. Chromosome condensation by a human condensin complex in Xenopus egg extracts. (PubMed id 11136719)1, 2, 3 Kimura K....Hirano T. (2001)
    3. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    7. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
    8. A cohesin-RAD21 interactome. (PubMed id 22145905)1 Panigrahi A.K....Pati D. (2012)
    9. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    10. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)

    External Searches for NCAPG gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing NCAPG gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 64151 HGNC: 24304 AceView: HCAP-G Ensembl:ENSG00000109805 euGenes: HUgn64151
    ECgene: NCAPG H-InvDB: NCAPG

    Other Databases showing NCAPG gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing NCAPG gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NCAPG Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for NCAPG gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for NCAPG gene:
    Search GeneIP for patents involving NCAPG

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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