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NCAPD3 Gene

protein-coding   GIFtS: 55
GCID: GC11M134022

Non-SMC Condensin II Complex, Subunit D3

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Non-SMC Condensin II Complex, Subunit D31 2     Condensin-2 Complex Subunit D32
CAPD32 3 5     hHCP-62
hCAP-D32 3     hcp-62
KIAA00563 5     Non-SMC Condensin II Complex Subunit D33
CAP-D32     

External Ids:    HGNC: 289521   Entrez Gene: 233102   Ensembl: ENSG000001515037   OMIM: 6092765   UniProtKB: P426953   

Export aliases for NCAPD3 gene to outside databases

Previous GC identifers: GC11M133529 GC11M129976


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for NCAPD3 Gene:
Condensin complexes I and II play essential roles in mitotic chromosome assembly and segregation. Both condensins
contain 2 invariant structural maintenance of chromosome (SMC) subunits, SMC2 (MIM 605576) and SMC4 (MIM 605575),
but they contain different sets of non-SMC subunits. NCAPD3 is 1 of 3 non-SMC subunits that define condensin II
(Ono et al., 2003 (PubMed 14532007)).(supplied by OMIM, Mar 2008)

GeneCards Summary for NCAPD3 Gene:
NCAPD3 (non-SMC condensin II complex, subunit D3) is a protein-coding gene. GO annotations related to this gene include methylated histone residue binding.

UniProtKB/Swiss-Prot: CNDD3_HUMAN, P42695
Function: Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome
architecture and is involved in physical rigidity of the chromatid axis

Gene Wiki entry for NCAPD3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NC_018922.2  NT_033899.9  
Regulatory elements:
   Regulatory transcription factor binding sites in the NCAPD3 gene promoter:
         MAZR   Pax-2   HNF-4alpha2   Pax-2a   HNF-4alpha1   POU2F1   COMP1   POU2F1a   c-Myb   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): NCAPD3 promoter sequence
   Search Chromatin IP Primers for NCAPD3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NCAPD3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q25   Ensembl cytogenetic band:  11q25   HGNC cytogenetic band: 11q25

NCAPD3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NCAPD3 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M134022:  view genomic region     (about GC identifiers)

Start:
134,020,014 bp from pter      End:
134,095,348 bp from pter
Size:
75,335 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: CNDD3_HUMAN, P42695 (See protein sequence)
Recommended Name: Condensin-2 complex subunit D3  
Size: 1498 amino acids; 168891 Da
Subunit: Component of the condensin-2 complex, which contains the SMC2 and SMC4 heterodimer, and 3 non SMC
subunits that probably regulate the complex: NCAPH2, NCAPD3 and NCAPG2. Interacts with BRD4 (isoform B), leading
to insulate chromatin from DNA damage response pathway
Secondary accessions: A6NFS2 Q4KMQ9

Explore the universe of human proteins at neXtProt for NCAPD3: NX_P42695

Explore proteomics data for NCAPD3 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys149, Lys442, Lys559, Lys597, Lys618, Lys743, Lys841, Lys929, Lys1258
  • Modification sites at PhosphoSitePlus

  • See NCAPD3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_056076.1  
    ENSEMBL proteins: 
     ENSP00000434168   ENSP00000433681   ENSP00000431612   ENSP00000432532   ENSP00000435173  
     ENSP00000431413   ENSP00000436037   ENSP00000431436   ENSP00000435586   ENSP00000435655  
    Reactome Protein details: P42695

    NCAPD3 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    5 InterPro protein domains:
     IPR011989 ARM-like
     IPR026003 Cohesin_HEAT
     IPR026971 CND1/NCAPD3
     IPR012371 NCAPD3
     IPR016024 ARM-type_fold

    Graphical View of Domain Structure for InterPro Entry P42695

    ProtoNet protein and cluster: P42695

    UniProtKB/Swiss-Prot: CNDD3_HUMAN, P42695
    Similarity: Contains 4 HEAT repeats


    Find genes that share domains with NCAPD3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CNDD3_HUMAN, P42695
    Function: Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome
    architecture and is involved in physical rigidity of the chromatid axis

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005488binding ----
    GO:0005515protein binding IPI17268547
    GO:0035064methylated histone residue binding IDA--
         
    Find genes that share ontologies with NCAPD3           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for NCAPD3

    miRNA
    Products:
        
    miRTarBase miRNAs that target NCAPD3:
    hsa-mir-186-5p (MIRT045217), hsa-mir-320a (MIRT044595), hsa-mir-1 (MIRT023702)

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    5 qRT-PCR Assays for microRNAs that regulate NCAPD3:
    hsa-miR-320a hsa-miR-320b hsa-miR-607 hsa-miR-320d hsa-miR-340
    SwitchGear 3'UTR luciferase reporter plasmidNCAPD3 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CNDD3_HUMAN, P42695: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000793condensed chromosome ----
    GO:0000799nuclear condensin complex IDA14532007
    GO:0005654nucleoplasm TAS--
    GO:0031618nuclear centromeric heterochromatin IDA--
    GO:0042585germinal vesicle IEA--

    Find genes that share ontologies with NCAPD3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for NCAPD3 About    
    See pathways by source

    SuperPathContained pathways About
    1Cell Cycle, Mitotic
    Cell Cycle, Mitotic0.90
    M Phase0.62
    Cell Cycle0.90
    2RNA Polymerase I Promoter Opening
    Condensation of Prophase Chromosomes0.78
    Mitotic Prophase0.56
    3Cell cycle Chromosome condensation in prometaphase
    Cell cycle Chromosome condensation in prometaphase


    Find genes that share SuperPaths with NCAPD3           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for NCAPD3
        Cell cycle Chromosome condensation in prometaphase

    1 Reactome Pathway for NCAPD3
        Condensation of Prophase Chromosomes


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NCAPD3
    Interactions:

        Search GeneGlobe Interaction Network for NCAPD3

    5 Interacting proteins for NCAPD3 (P426951, 2, 3) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NCAPH2Q6IBW41, 2, 3EBI-722805,EBI-2548296 MINT-4329904 MINT-4330100 I2D: score=1 
    PRSS23O950842, 3MINT-63245 I2D: score=5 
    MYCP011063I2D: score=1 
    SLX4Q8IY923I2D: score=1 
    UBCP0CG483I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000278mitotic cell cycle TAS--
    GO:0007076mitotic chromosome condensation IDA14532007

    Find genes that share ontologies with NCAPD3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NCAPD3 (CNDD3)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for NCAPD3 gene: 
    NM_015261.2  

    Unigene Cluster for NCAPD3:

    Non-SMC condensin II complex, subunit D3
    Hs.438550  [show with all ESTs]
    Unigene Representative Sequence: NM_015261
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000526787 ENST00000534532(uc001qhd.1 uc010scm.1 uc009zda.1)
    ENST00000534548 ENST00000525964 ENST00000525432 ENST00000527944 ENST00000530396
    ENST00000534290 ENST00000533155 ENST00000528065 ENST00000525485 ENST00000534227
    ENST00000526422 ENST00000532445
    miRNA
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    5 qRT-PCR Assays for microRNAs that regulate NCAPD3:
    hsa-miR-320a hsa-miR-320b hsa-miR-607 hsa-miR-320d hsa-miR-340
    SwitchGear 3'UTR luciferase reporter plasmidNCAPD3 3' UTR sequence
    Inhib. RNA
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    GenScript: all cDNA clones in your preferred vector: NCAPD3 (NM_015261)
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      QuantiTect SYBR Green Assays in human, mouse, rat NCAPD3
      QuantiFast Probe-based Assays in human, mouse, rat NCAPD3

    Additional mRNA sequence: 

    AF070553.1 AK025549.1 AK025667.1 AK095267.1 AK124878.1 BC011408.1 BC098398.1 BC144524.1 
    D29954.1 

    12 DOTS entries:

    DT.101968954  DT.215804  DT.99991702  DT.100754143  DT.92025751  DT.75128450  DT.97845008  DT.102833339 
    DT.120684392  DT.91747623  DT.95372608  DT.91754970 

    Selected AceView cDNA sequences (see all 177):

    AA430546 BM457351 BX436985 BF063720 D29954 BQ213070 BQ049693 AW205021 
    CR614818 N59634 BU177081 AI292183 BQ775870 BU172931 AI439728 BC011408 
    AW664344 CR601575 AL556801 BU176774 AL134281 AA412170 BE245345 AA778459 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for NCAPD3 (see all 9)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b · 9c ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19a · 19b ^
    SP1:                                -                       -                                                                                                   
    SP2:                                -                       -                                                                                                   
    SP3:                                -           -           -                                                                                                   
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 20 ^ 21 ^ 22 ^ 23a · 23b ^ 24 ^ 25 ^ 26 ^ 27 ^ 28 ^ 29a · 29b ^ 30 ^ 31 ^ 32 ^ 33 ^ 34a · 34b ^ 35a · 35b ^ 36 ^ 37 ^ 38 ^ 39a · 39b
    SP1:              -                                               -                                                     -     -                           
    SP2:              -                                                                                                     -     -                           
    SP3:                                                                                                                                                      
    SP4:                                                                                                                                                      
    SP5:                                                                                                                    -                                 


    ECgene alternative splicing isoforms for NCAPD3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NCAPD3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCCCTGAGCA
    NCAPD3 Expression
    About this image

    NCAPD3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NCAPD3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.438550
        Custom PCR Arrays for NCAPD3
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NCAPD3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for NCAPD3 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ncapd31 , 5 non-SMC condensin II complex, subunit D31, 5 79.22(n)1
    74.87(a)1
      9 (12.12 cM)5
    786581  NM_178113.31  NP_835214.21 
     270301755 
    chicken
    (Gallus gallus)
    Aves NCAPD31 non-SMC condensin II complex, subunit D3 65.02(n)
    61.46(a)
      419737  XM_004948008.1  XP_004948065.1 
    lizard
    (Anolis carolinensis)
    Reptilia NCAPD36
    non-SMC condensin II complex, subunit D3
    56(a)
    1 ↔ 1
    GL343396.1(860256-887631)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia ncapd31 non-SMC condensin II complex, subunit D3 61.87(n)
    59.74(a)
      100495597  XM_002937980.2  XP_002938026.2 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc555492 hypothetical protein MGC55549 72.93(n)   393301  BC052478.1 
    worm
    (Caenorhabditis elegans)
    Secernentea hcp-66
    Protein HCP-6, isoform b
    14(a)
    1 ↔ 1
    I(5165091-5171314) WBGene00001833
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT4G158901 AT4G15890 43.51(n)
    28.77(a)
      827271  NM_117681.2  NP_193324.1 
    rice
    (Oryza sativa)
    Liliopsida Os12g05481001 Os12g0548100 44.47(n)
    30.97(a)
      4352458  NM_001073501.1  NP_001066969.1 


    ENSEMBL Gene Tree for NCAPD3 (if available)
    TreeFam Gene Tree for NCAPD3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NCAPD3 (see all 1964)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1407241021,2
    C,Funtested1134023081(+) ACTCCG/AGCCTT 2 /R /W mis12Minor allele frequency- A:0.00NA EU 5677
    rs1870162071,2
    --134022187(+) CACAGA/CTGAAC 1 -- int10--------
    rs1915030861,2
    --134022215(+) ATCTTC/TTTTCT 1 -- int10--------
    rs1848192481,2
    --134022223(+) TCTAAC/TAGGGA 1 -- int10--------
    rs1893288481,2
    --134022322(+) AATCCC/TATTGA 1 -- int10--------
    rs1450051041,2
    --134022343(+) GCTGTA/GTTTAT 1 -- ut310--------
    rs112237171,2
    C,F,H--134022388(+) TTTTTT/AAAAAA 1 -- ut315Minor allele frequency- A:0.05NS EA NA 540
    rs1475714911,2
    C--134022439(+) ATTTCA/GTCATT 1 -- ut310--------
    rs1169760001,2
    F--134022495(+) CTTGAT/CTTATA 1 -- ut311Minor allele frequency- C:0.01EA 120
    rs1809737651,2
    --134022544(+) GACCAC/GATTAT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for NCAPD3 (134020014 - 134095348 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for NCAPD3:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2745322CNV Deletion23290073
    nsv898474CNV Loss21882294
    nsv832299CNV Loss17160897
    esv28602CNV Loss19812545
    nsv826147CNV Gain20364138
    nsv521581CNV Gain19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NCAPD3
    DNA2.0 Custom Variant and Variant Library Synthesis for NCAPD3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609276    OMIM disorders: --


    Find genes that share disorders with NCAPD3           About GenesLikeMe

    Genetic Association Database (GAD): NCAPD3
    Human Genome Epidemiology (HuGE) Navigator: NCAPD3 (1 document)

    Export disorders for NCAPD3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NCAPD3 gene, integrated from 10 sources (see all 37):
    (articles sorted by number of sources associating them with NCAPD3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Differential contributions of condensin I and condensin II to mitotic chromosome architecture in vertebrate cells. (PubMed id 14532007)1, 2, 3 Ono T.... Hirano T. (Cell 2003)
    2. Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 7584044)1, 2, 3 Nomura N.... Tabata S. (DNA Res. 1994)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. Genetic correlates of brain aging on MRI and cognitive test measures: a genome-wide association and linkage analysis in the Framingham Study. (PubMed id 17903297)1, 4 Seshadri S....Wolf P.A. (BMC Med. Genet. 2007)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. A "double adaptor" method for improved shotgun library construction. (PubMed id 8619474)1, 3 Andersson B.... Gibbs R.A. (Anal. Biochem. 1996)
    7. Identification of the hypoxia-inducible factor 2I+ nuclear interactome in melanoma cells reveals master proteins involved in melanoma development. (PubMed id 23275444)1 Steunou A.L....Nieto L. (amp 2013)
    8. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    9. The bromodomain protein Brd4 insulates chromatin from DNA damage signalling. (PubMed id 23728299)2 Floyd S.R.... Yaffe M.B. (Nature 2013)
    10. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (Sci Signal 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 23310 HGNC: 28952 AceView: KIAA0056 Ensembl:ENSG00000151503 euGenes: HUgn23310
    ECgene: NCAPD3 H-InvDB: NCAPD3

    (According to HUGE)
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    HUGE: KIAA0056

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for NCAPD3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NCAPD3 gene:
    Search GeneIP for patents involving NCAPD3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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