Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NCAM1 Gene

protein-coding   GIFtS: 73
GCID: GC11P112831

Neural Cell Adhesion Molecule 1

Alzheimer's & Parkinson's Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Neural Cell Adhesion Molecule 11 2     Neural Cell Adhesion Molecule, NCAM2
NCAM2 3     N-CAM-13
MSK392 5     NCAM-13
CD562     CD56 Antigen3
Antigen Recognized By Monoclonal Antibody 5.1H112     

External Ids:    HGNC: 76561   Entrez Gene: 46842   Ensembl: ENSG000001492947   OMIM: 1169305   UniProtKB: P135913   

Export aliases for NCAM1 gene to outside databases

Previous GC identifers: GC11P115185 GC11P114344 GC11P112866 GC11P112369 GC11P112337 GC11P108759


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NCAM1 Gene:
This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein
is involved in cell-to-cell interactions as well as cell-matrix interactions during development and
differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for
cells involved in the expansion of T cells and dendritic cells which play an important role in immune
surveillance. Alternative splicing results in multiple transcript variants. (provided by RefSeq, Jun 2011)

GeneCards Summary for NCAM1 Gene: 
NCAM1 (neural cell adhesion molecule 1) is a protein-coding gene. Diseases associated with NCAM1 include small cell carcinoma, and lethal midline granuloma, and among its related super-pathways are Axon guidance and Interferon Signaling. An important paralog of this gene is IGSF10.

UniProtKB/Swiss-Prot: NCAM1_HUMAN, P13591
Function: This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation,
outgrowth of neurites, etc

Gene Wiki entry for NCAM1 (Neural cell adhesion molecule) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.2  NT_033899.8  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NCAM1 gene promoter:
         AML1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNCAM1 promoter sequence
   Search SABiosciences Chromatin IP Primers for NCAM1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NCAM1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q23.1   Ensembl cytogenetic band:  11q23.2   HGNC cytogenetic band: 11q23.2

NCAM1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NCAM1 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P112831:  view genomic region     (about GC identifiers)

Start:
112,831,969 bp from pter      End:
113,149,158 bp from pter
Size:
317,190 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NCAM1_HUMAN, P13591 (See protein sequence)
Recommended Name: Neural cell adhesion molecule 1 precursor  
Size: 858 amino acids; 94574 Da
Subcellular location: Isoform 1: Cell membrane; Single-pass type I membrane protein
Subcellular location: Isoform 2: Cell membrane; Single-pass type I membrane protein
Subcellular location: Isoform 3: Cell membrane; Lipid-anchor, GPI-anchor
Subcellular location: Isoform 4: Cell membrane; Lipid-anchor, GPI-anchor (Potential)
Subcellular location: Isoform 5: Secreted
Subcellular location: Isoform 6: Secreted (Potential)
Sequence caution: Sequence=BAD92680.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
5 PDB 3D structures from and Proteopedia for NCAM1:
2E3V (3D)        2HAZ (3D)        2VKW (3D)        2VKX (3D)        3MTR (3D)    
Secondary accessions: A8K8T8 P13592 P13593 Q05C58 Q15829 Q16180 Q16209 Q59FL7 Q86X47 Q96CJ3
Alternative splicing: 6 isoforms:  P13591-2   P13591-1   P13591-3, P13592-2   P13591-4   P13591-5, P13592-1   P13591-6   (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for NCAM1: NX_P13591

Explore proteomics data for NCAM1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P13591

  • NCAM1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NCAM1 Protein Expression
    REFSEQ proteins (5 alternative transcripts): 
    NP_000606.3  NP_001070150.1  NP_001229536.1  NP_001229537.1  NP_851996.2  

    ENSEMBL proteins: 
     ENSP00000473281   ENSP00000474028   ENSP00000474891   ENSP00000475074   ENSP00000384055  
     ENSP00000318472  
    Reactome Protein details: P13591
    Human Recombinant Protein Products for NCAM1: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    R&D Systems Recombinant & Natural Proteins for NCAM1 (NCAM-1/CD56)
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for NCAM1
    OriGene Protein Over-expression Lysate for NCAM1
    OriGene MassSpec for NCAM1 
    OriGene Custom Protein Services for NCAM1
    GenScript Custom Purified and Recombinant Proteins Services for NCAM1
    Novus Biologicals NCAM1 Proteins
    Novus Biologicals NCAM1 Lysates
    Sino Biological Recombinant Protein for NCAM1
    Sino Biological Cell Lysate for NCAM1 
    ProSpec Recombinant Protein for NCAM1
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 5/11 cellular component terms (GO ID links to tree view) (see all 11):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane TAS--
    GO:0005576extracellular region IEA--
    GO:0005886plasma membrane TAS--
    GO:0009897external side of plasma membrane IDA17213291
    GO:0009986cell surface IDA10766765

    NCAM1 for ontologies           About GeneDecksing



    NCAM1 Antibody Products: 
    EMD Millipore Mono- and Polyclonal Antibodies for the study of NCAM1
    R&D Systems Antibodies for NCAM1 (NCAM-1/CD56)
    Cell Signaling Technology (CST) Antibodies for NCAM1 
    OriGene Antibodies for NCAM1
    OriGene Custom Antibody Services for NCAM1
    GenScript Superior Antibodies for NCAM1
    Novus Biologicals NCAM1 Antibodies
    Abcam antibodies for NCAM1
    Browse Antibodies at Cloud-Clone Corp. 
    ThermoFisher Antibody for NCAM1
    LSBio Antibodies in human, mouse, rat for NCAM1 

    Assay Products for NCAM1: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for NCAM1
    R&D Systems ELISAs for NCAM1 (NCAM-1/CD56)         (see all)
    GenScript Custom Assay Services for NCAM1
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp. 
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    FN3: Fibronectin type III domain containing
    CD: CD molecules
    ISET: Immunoglobulin superfamily / I-set domain containing

    5/6 InterPro protein domains (see all 6):
     IPR003598 Ig_sub2
     IPR003961 Fibronectin_type3
     IPR013098 Ig_I-set
     IPR009138 Neural_cell_adh
     IPR013783 Ig-like_fold

    Graphical View of Domain Structure for InterPro Entry P13591

    ProtoNet protein and cluster: P13591

    3 Blocks protein domains:
    IPB003598 Immunoglobulin C-2 type
    IPB009138 Neural cell adhesion molecule signature
    IPB013098 Immunoglobulin I-set


    UniProtKB/Swiss-Prot: NCAM1_HUMAN, P13591
    Similarity: Contains 2 fibronectin type-III domains
    Similarity: Contains 5 Ig-like C2-type (immunoglobulin-like) domains


    NCAM1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NCAM1_HUMAN, P13591
    Function: This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation,
    outgrowth of neurites, etc

         Genatlas biochemistry entry for NCAM1:
    cell adhesion molecule,neural,1,immunoglobulin superfamily

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0042802identical protein binding IPI--
         
    NCAM1 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for NCAM1:
     Decreased cell number, increas  Synthetic lethal with Ras  Synthetic lethal with c-Myc af 

         6 MGI mutant phenotypes (inferred from 6 alleles(MGI details for Ncam1):
     behavior/neurological  cellular  growth/size  mortality/aging  nervous system 
     vision/eye 

    NCAM1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for NCAM1: Ncam1tm2Mag Ncam1tm1.1Mag Ncam1tm1Cgn Ncam1tm1Mag

       inGenious Targeting Laboratory - Custom generated mouse model solutions for NCAM1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for NCAM1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NCAM1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NCAM1 

    miRNA
    Products:
        
    miRTarBase miRNAs that target NCAM1:
    hsa-mir-210 (MIRT003159), hsa-mir-122 (MIRT003090)

    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NCAM1
    8/37 QIAGEN miScript miRNA Assays for microRNAs that regulate NCAM1 (see all 37):
    hsa-miR-124* hsa-miR-100* hsa-miR-429 hsa-miR-128 hsa-miR-200a hsa-miR-16-1* hsa-miR-30d hsa-miR-141
    SwitchGear 3'UTR luciferase reporter plasmidNCAM1 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for NCAM1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NCAM1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for NCAM1
    Sirion Biotech Customized adenovirus for overexpression of NCAM1

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for NCAM1 (see all 15)
    OriGene ORF clones in mouse, rat for NCAM1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): NCAM1 (NM_001076682)
    Sino Biological Human cDNA Clone for NCAM1
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NCAM1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NCAM1
    Sirion Biotech Customized lentivirus for stable overexpression of NCAM1 
                         Customized lentivirus expression plasmids for stable overexpression of NCAM1 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for NCAM1
    LifeMap BioReagents: cell line associated with NCAM1: PureStem 4D20.8, NCr-fac Progenitor
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NCAM1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for NCAM1 About   (see all 16)                                                                                              See pathways by source

    SuperPathContained pathways About
    1Axon guidance
    Axon guidance0.69
    L1CAM interactions0.39
    Developmental Biology0.69
    Signal transduction by L10.32
    2Interferon Signaling
    Interferon Signaling0.61
    Interferon gamma signaling0.41
    Cytokine Signaling in Immune system0.61
    3NCAM signaling for neurite out-growth
    NCAM signaling for neurite out-growth0.62
    NCAM1 interactions0.62
    4Cell adhesion Cell-matrix glycoconjugates
    Cell adhesion Cell-matrix glycoconjugates0.97
    5Immune System
    Immune System0.56

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 EMD Millipore Pathway for NCAM1
        Cell adhesion Cell-matrix glycoconjugates


    3 Cell Signaling Technology (CST) Pathways for NCAM1
        Neuroscience
    Lymphocyte Signaling
    Adhesion

    1 GeneGo (Thomson Reuters) Pathway for NCAM1
        Cell adhesion Cell-matrix glycoconjugates

    3 BioSystems Pathways for NCAM1
        BDNF signaling pathway
    Cardiac Progenitor Differentiation
    FGF signaling pathway

    1 Sino Biological Pathway for NCAM1 
        TGF-beta Signaling Pathway

    5/12        Reactome Pathways for NCAM1 (see all 12)
        L1CAM interactions
    Developmental Biology
    Interferon gamma signaling
    Cytokine Signaling in Immune system
    NCAM1 interactions


    2         Kegg Pathways  (Kegg details for NCAM1):
        Cell adhesion molecules (CAMs)
    Prion diseases


    NCAM1 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for NCAM1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/91 Interacting proteins for NCAM1 (P135912, 3 ENSP000003184724) via UniProtKB, MINT, STRING, and/or I2D (see all 91)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    BDNFP235603, ENSP000004143034I2D: score=1 STRING: ENSP00000414303
    GDNFP399053, ENSP000003171454I2D: score=1 STRING: ENSP00000317145
    MDKP217413, ENSP000003528524I2D: score=1 STRING: ENSP00000352852
    PRKCBP057713, ENSP000003053554I2D: score=1 STRING: ENSP00000305355
    SPTBP112773, ENSP000003743724I2D: score=1 STRING: ENSP00000374372
    About this table

    Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001928regulation of exocyst assembly ----
    GO:0007155cell adhesion IEA--
    GO:0007166cell surface receptor signaling pathway ----
    GO:0007411axon guidance TAS--
    GO:0019221cytokine-mediated signaling pathway TAS--

    NCAM1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    NCAM1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Compounds for NCAM1 available from Tocris Bioscience    About this table
    CompoundAction CAS #
    ThiolutinBacterial RNA polymerase inhibitor[87-11-6]
    Heparin sodium saltAnticoagulant[9041-08-1]
    Echistatin, alpha1 isoform alphaVbeta3 and glycoprotein IIb/IIIa (integrin alphaIIbbeta3) inhibitor[154303-05-6]
    RGDS peptideIntegrin binding sequence; inhibits integrin receptor function[91037-65-9]
    Ac2-26Annexin/lipocortin 1-mimetic; inhibits leukocyte extravasation[151988-33-9]

    10/57 Novoseek inferred chemical compound relationships for NCAM1 gene (see all 57)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    nkh 1 75.8 1 1706237 (1)
    fuc-gm1 64.6 1 7982239 (1)
    sialic acid 53.4 32 17986141 (3), 9774483 (2), 8567623 (2), 1891065 (1) (see all 21)
    neurocan 49.9 17 8910306 (5), 7513709 (4), 8663515 (2), 11766883 (1)
    smcc 38.1 3 15010880 (1), 14652811 (1)
    retinoic acid 36.1 21 7522652 (3), 10222420 (3), 9222276 (2), 16469417 (2) (see all 8)
    chondroitin sulfate 33.1 13 16181411 (3), 8663515 (2), 8910306 (2), 7513709 (2) (see all 6)
    paraffin 28 9 9416693 (2), 14959847 (2), 10821486 (1), 15309466 (1) (see all 6)
    tyrosine 27.7 17 9559292 (1), 9168199 (1), 11520897 (1), 18772882 (1) (see all 16)
    polysaccharide 17 12 12791681 (3), 18981104 (2), 7726560 (2), 11598089 (1) (see all 8)

    Search CenterWatch for drugs/clinical trials and news about NCAM1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NCAM1 gene (5 alternative transcripts): 
    NM_000615.6  NM_001076682.3  NM_001242607.1  NM_001242608.1  NM_181351.4  

    Unigene Clusters for NCAM1:

    Neural cell adhesion molecule 1
    Hs.503878  [show with all ESTs], Hs.733031  [show with all ESTs]
    Unigene Representative Sequences: NM_001242607, X55322
    18/30 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 30):
    ENST00000531915 ENST00000527506 ENST00000533760(uc001pnp.3 uc021qqo.1)
    ENST00000528742 ENST00000397957(uc021qqp.1 uc001pnq.3 uc001pnr.3 uc001pns.3)
    ENST00000534618 ENST00000526427 ENST00000524665 ENST00000529420(uc001pno.3)
    ENST00000531838 ENST00000534015 ENST00000525973 ENST00000531044 ENST00000529356
    ENST00000534046 ENST00000530543 ENST00000526322 ENST00000531817

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NCAM1
    8/37 QIAGEN miScript miRNA Assays for microRNAs that regulate NCAM1 (see all 37):
    hsa-miR-124* hsa-miR-100* hsa-miR-429 hsa-miR-128 hsa-miR-200a hsa-miR-16-1* hsa-miR-30d hsa-miR-141
    SwitchGear 3'UTR luciferase reporter plasmidNCAM1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for NCAM1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NCAM1
    Clone
    Products:
         
    OriGene clones in human, mouse for NCAM1 (see all 15)
    OriGene ORF clones in mouse, rat for NCAM1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): NCAM1 (NM_001076682)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NCAM1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NCAM1
    Sirion Biotech Customized lentivirus for stable overexpression of NCAM1 
                         Customized lentivirus expression plasmids for stable overexpression of NCAM1 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for NCAM1
    OriGene qSTAR qPCR primer pairs in human, mouse for NCAM1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NCAM1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NCAM1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NCAM1

    Additional mRNA sequence: X55322.1 

    24/26 DOTS entries (see all 26):

    DT.120699894  DT.100786315  DT.91779848  DT.91947069  DT.120699994  DT.95243682  DT.87017842  DT.305278 
    DT.100786313  DT.101973402  DT.319668  DT.120700032  DT.100677975  DT.120699897  DT.120699900  DT.120699934 
    DT.120699940  DT.120699950  DT.120699974  DT.120699977  DT.40262367  DT.423052  DT.95267640  DT.120699938 

    24/303 AceView cDNA sequences (see all 303):

    AW007527 AU124625 AW129092 AA814497 BM709462 BM784425 BM706422 R58905 
    AI274486 BM692477 AI127688 AV725113 BI493304 BE205776 AA130100 AI273489 
    AI264045 AW768954 AA082299 CR600745 BF341180 BQ720682 M22094 AW016503 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for NCAM1    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15a · 15b ^ 16a · 16b ^ 17a · 17b ^ 18 ^ 19 ^ 20
    SP1:                                                                                      -           -     -     -                 -         
    SP2:                                            -                                         -                                                   
    SP3:                                                                                                                                          
    SP4:                                                                                                                                          
    SP5:                                                                                                                                          


    ECgene alternative splicing isoforms for NCAM1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NCAM1 expression in normal human tissues (normalized intensities)      NCAM1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAAGAGTTTT
    NCAM1 Expression
    About this image


    NCAM1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/34 selected tissues (see all 34) fully expand
     
     Bone (Muscoskeletal System)    fully expand to see all 18 entries
             Prechondrocytes Synchondroses
             Human Mesenchymal Stem Cell-bone marrow (HMSC-Bone Marrow)   
     
     Brain (Nervous System)    fully expand to see all 13 entries
             Cerebral Cortex
             GABA neuron-like cells ( Generation of motor and gamma-aminobutyric acid (GABA)...
             Olfactory Bulb   
     
     Cartilage (Muscoskeletal System)    fully expand to see all 13 entries
             Prechondrocytes Synchondroses
     
     Peripheral Nervous System (Nervous System)    fully expand to see all 7 entries
             Non-myelinating Schwann Cells Peripheral Nerve Domain
             colon ; peripheral nerve/ganglion   
             autonomic/sympathetic/ganglion   
     
     Blood (Hematopoietic System)    fully expand to see all 5 entries
             Natural Killer Cells Peripheral Blood
             Facilitating cells
             Natural killer-like cells ( Derivation of hematopoietic progenitor cells and natural...
             Human Mesenchymal Stem Cell-bone marrow (HMSC-Bone Marrow)   

    See NCAM1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NCAM1

    SOURCE GeneReport for Unigene clusters: Hs.503878 Hs.733031
        SABiosciences Expression via Pathway-Focused PCR Arrays including NCAM1 (see all 6): 
              cAMP / Ca2+ Signaling PathwayFinder in human mouse rat
              Extracellular Matrix & Adhesion Molecules in human mouse rat
              Cell Surface Markers in human mouse rat
              Lymphoma in human mouse rat
              Synaptic Plasticity in human mouse rat

    Primer
    Products:
    OriGene qPCR primer pairs and template standards for NCAM1
    OriGene qSTAR qPCR primer pairs in human, mouse for NCAM1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NCAM1
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NCAM1
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NCAM1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NCAM1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for NCAM1 gene from 7/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ncam11 , 5 neural cell adhesion molecule 11, 5 87.76(n)1
    92.59(a)1
      9 (26.83 cM)5
    179671  NM_001113204.11  NP_001106675.11 
     495043615 
    chicken
    (Gallus gallus)
    Aves NCAM11 neural cell adhesion molecule 1 81.93(n)
    88.37(a)
      428253  NM_001128828.1  NP_001122300.1 
    lizard
    (Anolis carolinensis)
    Reptilia NCAM16
    neural cell adhesion molecule 1
    64(a)
    1 ↔ 1
    GL343354.1(608176-754576)
    African clawed frog
    (Xenopus laevis)
    Amphibia NCAM2 cell adhesion molecule 76.27(n)    M76710.1 
    zebrafish
    (Danio rerio)
    Actinopterygii AY029402.12   -- 75.44(n)   30447  AY029402.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Fas23 homophilic cell adhesion 26(a)     --
    worm
    (Caenorhabditis elegans)
    Secernentea ncam-16
    wrk-16
    (see all 3)
    Protein WRK-1, isoform a
    (see all 3)
    19(a)
    17(a)
    (see all 3)
    1 ↔ many
    possible ortholog
    (see all 3)
    X(692978-703036)
    X(8387467-8392582)


    ENSEMBL Gene Tree for NCAM1 (if available)
    TreeFam Gene Tree for NCAM1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NCAM1 gene
    IGSF102  NCAM22  DSCAM2  ENSG000002154282  DSCAML12  MXRA52  
    5 SIMAP similar genes for NCAM1 using alignment to 5 protein entries:     NCAM1_HUMAN (see all proteins):
    NCAM2    NTM    OPCML    DCC    K-SAM

    NCAM1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/6600 SNPs in NCAM1 are shown (see all 6600)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0613314
    ----see VAR_0613312 L F mis40--------
    rs1997587531,2
    C--108762564(+) TTTTTG/TTGTTT 5 -- int10--------
    rs591781811,2
    C--108762567(+) TTTTT-/TTGGACT 5 -- int10--------
    rs677115321,2
    C--108810427(+) TCCTTC/TCTTTC 5 -- int11Minor allele frequency- T:0.50WA 2
    rs340017511,2
    C--108811840(+) AAAAA-/AGAAGC 5 -- int11Minor allele frequency- A:0.00NA 2
    rs359886811,2
    C--108849943(+) CACCT-/AAAAAA 5 -- int11Minor allele frequency- A:0.00NA 2
    rs113734491,2
    C--108871141(+) TCATC-/TTTTTT 5 -- int10--------
    rs678497371,2
    C--108871142(+) TTTTT-/TAACTT 5 -- int10--------
    rs105350041,2
    C--108876095(+) AGTAC-/T/TT  
            
    TTTTT
    5 -- int11CSA 2
    rs344209401,2
    C--108879667(+) AGGAC-/GGGGGT 5 -- int12Minor allele frequency- G:0.25NA CSA 4

    HapMap Linkage Disequilibrium report for NCAM1 (112831969 - 113081969 bp, first 250kb of NCAM1)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for NCAM1:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2745085CNV Deletion23290073
    esv2664094CNV Deletion23128226
    nsv516224CNV Loss19592680
    nsv526604CNV Loss19592680
    esv24924CNV Loss19812545
    nsv468870CNV Loss19166990
    nsv515828CNV Loss19592680
    nsv832271CNV Gain17160897
    nsv832272CNV Gain17160897


    Human Gene Mutation Database (HGMD): NCAM1
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing NCAM1
    DNA2.0 Custom Variant and Variant Library Synthesis for NCAM1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 116930    OMIM disorders: --

    20/150 diseases for NCAM1 (see all 150):    About MalaCards
    small cell carcinoma    lethal midline granuloma    gastric small cell carcinoma    plasma cell leukemia
    bile duct disease    prostate small cell carcinoma    transitional meningioma    monoclonal gammopathy of uncertain significance
    chordoid meningioma    meninges hemangiopericytoma    pancreatic endocrine carcinoma    myeloid sarcoma
    reticulosarcoma    myxopapillary ependymoma    sarcoglycanopathies    pancreas adenocarcinoma
    primary pigmented nodular adrenocortical disease    panniculitis    ependymoma    centronuclear myopathy

    11 diseases from the University of Copenhagen DISEASES database for NCAM1:
    Lymphoma     Leukemia     Multiple myeloma     Carcinoma
    Lung cancer     Hemophagocytic lymphohistiocytosis     Leukopenia     Neuroblastoma
    Hypersensitivity reaction type II disease     Germ cell cancer     Myeloid sarcoma

    NCAM1 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    10/92 Novoseek inferred disease relationships for NCAM1 gene (see all 92)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    small cell lung cancer 65.1 37 16159442 (6), 9416693 (3), 2165922 (3), 1314069 (1) (see all 18)
    carcinoma neuroendocrine 58.5 4 18726606 (1), 8141431 (1), 7773512 (1)
    peripheral neuroepithelioma 49.6 1 1867319 (1)
    neuroendocrine tumors 49.2 9 10821486 (1), 12744370 (1), 16115052 (1), 15242781 (1) (see all 8)
    carcinoma merkel cell 49.1 5 16115052 (3), 7773512 (2)
    sma ii 47.4 1 8583219 (1)
    tumors 46.4 236 9587126 (7), 12744370 (6), 11249065 (5), 7523154 (5) (see all 99)
    plasma cell myeloma 43.9 7 1721526 (2), 8520507 (1), 17122631 (1), 18480010 (1)
    centronuclear myopathy 43.7 2 1517767 (1), 7969799 (1)
    hirschsprung disease 42.7 10 8689902 (3), 11854929 (2), 8176609 (2), 8405855 (2) (see all 5)

    Genetic Association Database (GAD): NCAM1
    Human Genome Epidemiology (HuGE) Navigator: NCAM1 (30 documents)

    Export disorders for NCAM1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NCAM1 gene, integrated from 9 sources (see all 804):
    (articles sorted by number of sources associating them with NCAM1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular and functional analysis of human natural killer cell- associated neural cell adhesion molecule (N-CAM/CD56). (PubMed id 1710251)1, 2, 9 Lanier L.L....Phillips J.H. (1991)
    2. Splicing of the VASE exon of neural cell adhesion molecule (NCAM) in human small-cell lung carcinoma (SCLC). (PubMed id 1339414)1, 2, 9 van Duijnhoven H.L.... Patel K. (1992)
    3. Genetic variation in NCAM1 contributes to left ventri cular wall thickness in hypertensive families. (PubMed id 21212386)1, 4 Arnett D.K....Kardia S.L. (2011)
    4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    5. Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease. (PubMed id 21116278)1, 4 Furney S.J....Lovestone S. (2010)
    6. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
    7. Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population. (PubMed id 19328558)1, 4 Yosifova A....Nakamura Y. (2009)
    8. No genetic association between NCAM1 gene polymorphisms and schizophrenia in the Chinese population. (PubMed id 18601968)1, 4 Xu Z....Shi Y. (2008)
    9. Haplotypic Variants in DRD2, ANKK1, TTC12, and NCAM1 are Associated With Comorbid Alcohol and Drug Dependence. (PubMed id 18828801)1, 4 Yang B.Z....Gelernter J. (2008)
    10. Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. (PubMed id 19086053)1, 4 GratacA^s M....Carracedo A. (2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 4684 HGNC: 7656 AceView: NCAM1 Ensembl:ENSG00000149294 euGenes: HUgn4684
    ECgene: NCAM1 Kegg: 4684 H-InvDB: NCAM1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NCAM1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for NCAM1 Genetics and Cytogenetics in Oncology and Haematology
    Wikipedia http://en.wikipedia.org/wiki/NCAM
    Functional Glycomics Gateway - Glycan Bindinghttp://www.functionalglycomics.org/glycomics/GBPServlet?&operationType=view&cbpId=cbp_hum_Itlect_264

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NCAM1 gene:
    Search GeneIP for patents involving NCAM1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     Browse Purified and Recombinant Proteins at EMD Millipore
     Browse for Gene Knock-down Tools from EMD Millipore
     EMD Millipore Mono- and Polyclonal Antibodies for the study of NCAM1
     Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
     Browse Small Molecules at EMD Millipore
     Browse Kits and Assays available from EMD Millipore
     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Antibodies for NCAM1 (NCAM-1/CD56)   Browse Cell Culture Products  
     ELISAs for NCAM1 (NCAM-1/CD56)   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Cell Selection/Detection Kits/Reagents for NCAM1 (NCAM-1/CD56)   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Recombinant/Natural Proteins for NCAM1 (NCAM-1/CD56)  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Proteome Profiler Antibody Arrays for NCAM1 (NCAM-1/CD56)  
     OriGene Antibodies for NCAM1   OriGene RNAi products in human, mouse, rat for NCAM1  
     OriGene qPCR primer pairs and template standards for NCAM1   OriGene Protein Over-expression Lysate for NCAM1  
     OriGene MassSpec something-or-other for NCAM1   OriGene clones in human, mouse for NCAM1  
     OriGene qSTAR qPCR primer pairs in human, mouse for NCAM1   OriGene Purified Protein for NCAM1  
     OriGene ORF clones in mouse, rat for NCAM1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for NCAM1   OriGene Custom Protein Services for NCAM1  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NCAM1
     QIAGEN SeqTarget long-range PCR primers for resequencing NCAM1
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NCAM1
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NCAM1
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NCAM1
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NCAM1
     GenScript Custom Purified and Recombinant Proteins Services for NCAM1 GenScript cDNA clones with any tag delivered in your preferred vector for NCAM1
     GenScript Custom Assay Services for NCAM1 GenScript Superior Antibodies for NCAM1
     GenScript Custom overexpressing Cell Line Services for NCAM1 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Antibodies & Assays for NCAM1 

     Regulatory tfbs in NCAM1 promoter
     Search Chromatin IP Primers for NCAM1
     RT2 qPCR Primer Assay in human, mouse, rat NCAM1
     GNC Network for NCAM1
     SABiosciences PCR Arrays including human, mouse, rat NCAM1
     Tocris compounds for NCAM1
     Proteins and Antibodies for NCAM1
     Cell Lysates for NCAM1
     cDNA Clones for NCAM1
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     NCAM1 antibodies
     NCAM1 proteins
     NCAM1 lysates
     Antibodies for NCAM1
     See all of Abcam's Antibodies, Kits and Proteins for NCAM1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Recombinant Protein for NCAM1




     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.
     Cell Line associated with NCAM1: PureStem 4D20.8, NCr-fac Progenitor
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NCAM1
     SwitchGear 3'UTR luciferase reporter plasmids for NCAM1
     SwitchGear Promoter luciferase reporter plasmids for NCAM1
     ThermoFisher Antibody for NCAM1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NCAM1
     inGenious Targeting Laboratory - Custom generated mouse model solutions for NCAM1
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for NCAM1
    Customized:
     lentivirus for stable overexpression of NCAM1
     lentivirus expression plasmids for stable overexpression of NCAM1
     adenovirus for overexpression of NCAM1
     LSBio Antibodies in human, mouse, rat for NCAM1
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      NCAM1 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4