Aliases for NCAM1 Gene
External Ids for NCAM1 Gene
Previous GeneCards Identifiers for NCAM1 Gene
This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]
GeneCards Summary for NCAM1 Gene
NCAM1 (Neural Cell Adhesion Molecule 1) is a Protein Coding gene. Diseases associated with NCAM1 include Rabies and Hypoganglionosis. Among its related pathways are Interleukin-3, 5 and GM-CSF signaling and TGF-beta Signaling Pathway (sino). GO annotations related to this gene include identical protein binding. An important paralog of this gene is NCAM2.
UniProtKB/Swiss-Prot for NCAM1 Gene
This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.
(Microbial infection) Acts as a receptor for rabies virus.
Cell adhesion molecules (CAMs) are a large family of transmembrane proteins that are involved in the binding of a cell to another cell or to the extracellular matrix. They have roles in cell proliferation, differentiation, motility, trafficking, apoptosis and tissue architecture.