NBPF8 Gene
protein-coding GIFtS: 32
GCID: GC01P144166
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NBPF8
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Aliases
for NBPF8 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| NBPF212 | | Hypothetical Protein LOC7288412 | | Neuroblastoma Breakpoint Family, Member 82 |
Export aliases for NBPF8 gene to outside databasesPrevious GC identifers: GC01U901189 GC01M144745 GC01P142861 GC01P143315 GC01P144147 GC01P144150 GC01P144154 |
Summaries
for NBPF8 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for NBPF8 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NT_079497.3 NC_018912.1
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for NBPF8
Other transcription factors
Search SABiosciences Chromatin IP Primers for NBPF8
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NBPF8 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q21.1 Ensembl cytogenetic band: 1q21.1 NBPF8 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P144166: view genomic region
(about GC identifiers)
Start:
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144,146,787 bp from pter |
End:
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144,224,481 bp from pter |
Size:
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77,695 bases |
Orientation:
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plus strand |
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Proteins
for NBPF8 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: NBPF8_HUMAN, Q3BBV2 (See
protein sequence)Recommended Name: Neuroblastoma breakpoint family member 8 Size: 869 amino acids; 99215 Da
Subcellular location: Cytoplasm (Probable)
Miscellaneous: Encoded by one of the numerous copies of NBPF genes clustered in the p36, p12 and q21 region of thechromosome 1Explore the universe of human proteins at neXtProt for NBPF8: NX_Q3BBV2
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q3BBV2
NBPF8 Protein expression data from MOPED and PaxDb: About this image 
ENSEMBL proteins: ENSP00000404564 ENSP00000358372 ENSP00000358191 ENSP00000358379 ENSP00000349255 ENSP00000412038 ENSP00000358380
Human Recombinant Protein Products for NBPF8:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005737 | cytoplasm |
IEA | -- |
NBPF8 for ontologies About GeneDecksing
NBPF8 Antibody Products:
Assay Products for NBPF8: |
Protein
Domains /
Families
for NBPF8 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
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NBPF8 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q3BBV2ProtoNet protein and cluster: Q3BBV2 UniProtKB/Swiss-Prot: NBPF8_HUMAN, Q3BBV2Similarity: Belongs to the NBPF familySimilarity: Contains 7 NBPF domains |
Function
for NBPF8 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
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Animal Models:
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Pathways & Interactions
for NBPF8 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
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Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NBPF8
STRING Interaction
Network Preview (showing 4 interactants - click image to see more details)
4 Interacting proteins for NBPF8 (Q3BBV23 ENSP000003583724) via UniProtKB, MINT, STRING, and/or I2DAbout this table
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Drugs & Compounds
for NBPF8 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for NBPF8
Search CenterWatch for drugs/clinical trials and news about NBPF8 
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Transcripts
for NBPF8 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for NBPF8 gene: NM_001037501.1 Unigene Clusters for NBPF8: Neuroblastoma breakpoint family, member 8 Hs.534675 [show with all ESTs], Hs.744197 [show with all ESTs]Unigene Representative Sequences: XR_110613, XR_1712407 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000412624 ENST00000369365(uc021oti.1 uc001ejz.1 uc021otn.1 uc021otm.1 uc021otl.1 uc021otq.1 uc021ott.1 uc021otk.1 uc001ekl.2 uc010oyb.2 uc021otw.1 uc021otx.1 uc021otp.1 uc021otu.1 uc021otv.1 uc010oxn.1 uc021oth.1 uc021otj.1 uc021oto.1 uc021otr.1 uc001ekk.1 uc021ots.1)
ENST00000369190 ENST00000369372 ENST00000356801 ENST00000421555 ENST00000369373
Additional cDNA sequence: XR_171240.1 24/49 DOTS entries (see all 49): DT.87017630 DT.100650944 DT.97782066 DT.121435708 DT.92387747 DT.121435547 DT.102841682 DT.91708312 DT.121435771 DT.87017632 DT.95083311 DT.100861446 DT.121435658 DT.40260980 DT.100058829 DT.97759826 DT.100059221 DT.100646648 DT.87078282 DT.91974142 DT.95247186 DT.95378315 DT.100059352 DT.121460329
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for NBPF8 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5 | ^ | 6 |
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| SP1: | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | - | | - | | - | | | | |
| SP3: | | | | | | | | | | | | | | | | | | |
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Expression
for NBPF8 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| NBPF8 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See NBPF8 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NBPF8
SOURCE GeneReport for Unigene clusters: Hs.534675 Hs.744197
UniProtKB/Swiss-Prot: NBPF8_HUMAN, Q3BBV2Tissue specificity: Expressed in the mammary gland
SABiosciences Custom PCR Arrays for NBPF8
Primer
Products: |  | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat NBPF8 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NBPF8 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NBPF8 |
Orthologs
for NBPF8 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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--
ENSEMBL Gene Tree for NBPF8 (if available)
TreeFam Gene Tree for NBPF8 (if available) |
Paralogs
for NBPF8 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for NBPF8 gene
- NBPF32 NBPF62 NBPF202 ENSG000002326372 NBPF162 NBPF92 NBPF42 NBPF112
- NBPF242 NBPF152 NBPF142 NBPF102 NBPF122
18 SIMAP similar genes for NBPF8 using alignment to 2 protein entries: NBPF8_HUMAN (see all proteins):NBPF15 NBPF16 NBPF1 NBPF14 AL592307.2 LOC101059961
NBPF24 NBPF20 NBPF21 NBPF12 NBPF9 NBPF11
NBPF10 NBPF3 NBPF7 NBPF5 NBPF6 NBPF4
NBPF8 for paralogs About GeneDecksing
5/10 Pseudogenes.org Pseudogenes for NBPF8 (see all 10)
PGOHUM00000259451 PGOHUM00000259452 PGOHUM00000259479 PGOHUM00000259480 PGOHUM00000244217
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Genomic Variants
for NBPF8 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
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| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for NBPF8 (144146787 - 144224481 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for NBPF8: -- | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for NBPF8 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
NBPF8 for disorders About GeneDecksing
OMIM gene information: 613998
OMIM disorders: --
1  disease for NBPF8: About MalaCardsneuroblastoma
1 disease from the University of Copenhagen DISEASES database for NBPF8:Genital herpes Export disorders for NBPF8 gene to outside databases
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Publications
for NBPF8 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for NBPF8 gene integrated from 9 sources:
(articles sorted by number of sources associating them with NBPF8) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution. (PubMed id 16079250)1, 2 Vandepoele K.... van Roy F. (2005)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for NBPF8 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing NBPF8 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing NBPF8 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NBPF8 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for NBPF8 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for NBPF8 gene:
Search GeneIP for patents involving NBPF8
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for NBPF8 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NBPF8 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NBPF8 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NBPF8 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NBPF8 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NBPF8 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NBPF8 |
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| | | | Search Tocris compounds for NBPF8 |
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 | | | NBPF8 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  |  | | | | Search ThermoFisher Antibodies for NBPF8 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NBPF8 |
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