Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NBPF3 Gene

protein-coding   GIFtS: 46
GCID: GC01P021766

Neuroblastoma Breakpoint Family, Member 3

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Neuroblastoma Breakpoint Family, Member 31 2
Protein SHIIIa42 3
AE22
Neuroblastoma Breakpoint Family Member 32
Protein AE23

External Ids:    HGNC: 250761   Entrez Gene: 842242   Ensembl: ENSG000001427947   OMIM: 6129925   UniProtKB: Q9H0943   

Export aliases for NBPF3 gene to outside databases

Previous GC identifers: GC01P021512 GC01P021639 GC01P020010


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NBPF3 Gene:
This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently
duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has
experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates
in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains.
DUF1220 copy number variations in human chromosomal region 1q21.1, where most DUF1220 domains are located, have
been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly,
autism, schizophrenia, mental retardation, congenital heart disease, neuroblastoma, and congenital kidney and
urinary tract anomalies. Altered expression of some gene family members is associated with several types of
cancer. This gene family contains numerous pseudogenes. (provided by RefSeq, Feb 2013)

GeneCards Summary for NBPF3 Gene: 
NBPF3 (neuroblastoma breakpoint family, member 3) is a protein-coding gene. Diseases associated with NBPF3 include neuroblastoma, and non-small cell lung carcinoma. An important paralog of this gene is NBPF6.

Gene Wiki entry for NBPF3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.2  NT_004610.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NBPF3 gene promoter:
         Max1   p53   AP-4   AREB6   CREB   HEN1   deltaCREB   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNBPF3 promoter sequence
   Search SABiosciences Chromatin IP Primers for NBPF3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NBPF3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p36.12   Ensembl cytogenetic band:  1p36.12   HGNC cytogenetic band: 1p36.12

NBPF3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NBPF3 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P021766:  view genomic region     (about GC identifiers)

Start:
21,766,621 bp from pter      End:
21,811,498 bp from pter
Size:
44,878 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NBPF3_HUMAN, Q9H094 (See protein sequence)
Recommended Name: Neuroblastoma breakpoint family member 3  
Size: 633 amino acids; 72951 Da
Subcellular location: Cytoplasm (Probable)
Miscellaneous: Encoded by one of the numerous copies of NBPF genes clustered in the p36, p12 and q21 region of the
chromosome 1
Sequence caution: Sequence=AAH24011.1; Type=Frameshift; Positions=252; Sequence=CAH72077.1; Type=Erroneous gene
model prediction; Sequence=CAH72078.1; Type=Erroneous gene model prediction;
Secondary accessions: A8K965 B4DSP2 I3L0I8 Q3BBW1 Q5VTG2 Q5VTG3 Q5VTG4 Q8IX78 Q8ND86 Q8TC96
Alternative splicing: 5 isoforms:  Q9H094-1   Q9H094-2   Q9H094-3   Q9H094-4   Q9H094-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NBPF3: NX_Q9H094

Explore proteomics data for NBPF3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9H094

  • NBPF3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NBPF3 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001243345.1  NP_001243346.1  NP_115640.1  

    ENSEMBL proteins: 
     ENSP00000316739   ENSP00000340336   ENSP00000391865   ENSP00000415711   ENSP00000316782  

    Human Recombinant Protein Products for NBPF3: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for NBPF3
    GenScript Custom Purified and Recombinant Proteins Services for NBPF3
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for NBPF3 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--

    NBPF3 for ontologies           About GeneDecksing



    NBPF3 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for NBPF3
    GenScript Custom Superior Antibodies Services for NBPF3
    Search for Antibodies for NBPF3 at Abcam
    Cloud-Clone Corp. Antibodies for NBPF3 
    ThermoFisher Antibodies for NBPF3
    Search LSBio for Antibodies for NBPF3 

    Assay Products for NBPF3: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for NBPF3
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for NBPF3
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for NBPF3 
    Cloud-Clone Corp. CLIAs for NBPF3


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    NBPF: neuroblastoma breakpoint family

    1 InterPro protein domain:
     IPR010630 NBPF_dom

    Graphical View of Domain Structure for InterPro Entry Q9H094

    ProtoNet protein and cluster: Q9H094

    UniProtKB/Swiss-Prot: NBPF3_HUMAN, Q9H094
    Similarity: Belongs to the NBPF family
    Similarity: Contains 5 NBPF domains


    NBPF3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Phenotypes:
         1 GenomeRNAi human phenotype for NBPF3:
     Increased G1 DNA content 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for NBPF3 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for NBPF3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NBPF3 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NBPF3 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NBPF3
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate NBPF3
    SwitchGear 3'UTR luciferase reporter plasmidNBPF3 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for NBPF3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NBPF3

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for NBPF3
    Sirion Biotech Customized adenovirus for overexpression of NBPF3

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for NBPF3 (see all 4)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NBPF3 (NM_032264)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NBPF3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NBPF3
    Sirion Biotech Customized lentivirus for stable overexpression of NBPF3 
                         Customized lentivirus expression plasmids for stable overexpression of NBPF3 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for NBPF3
    Search LifeMap BioReagents cell lines for NBPF3
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NBPF3


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for NBPF3

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5/8 Interacting proteins for NBPF3 (Q9H0942, 3 ENSP000003167824) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TSEN15Q8WW013, ENSP000003552994I2D: score=3 STRING: ENSP00000355299
    ANK1P161573, ENSP000002657094I2D: score=1 STRING: ENSP00000265709
    EWSR1Q018443, ENSP000003810314I2D: score=3 STRING: ENSP00000381031
    UBCENSP000003448184STRING: ENSP00000344818
    --Q9BWA23, 2MINT-67372 I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NBPF3

    Search CenterWatch for drugs/clinical trials and news about NBPF3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NBPF3 gene (3 alternative transcripts): 
    NM_001256416.2  NM_001256417.2  NM_032264.4  

    Unigene Cluster for NBPF3:

    Neuroblastoma breakpoint family, member 3
    Hs.325422  [show with all ESTs]
    Unigene Representative Sequence: NR_046176
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000475869 ENST00000318220(uc001ber.3 uc001bes.3 uc010odm.2)
    ENST00000478653 ENST00000485941 ENST00000342104(uc009vqb.3) ENST00000486229
    ENST00000434838 ENST00000467103 ENST00000469876 ENST00000477050 ENST00000454000
    ENST00000318249
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NBPF3
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate NBPF3
    SwitchGear 3'UTR luciferase reporter plasmidNBPF3 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for NBPF3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NBPF3
    Clone
    Products:
         
    OriGene clones in human, mouse for NBPF3 (see all 4)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NBPF3 (NM_032264)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NBPF3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NBPF3
    Sirion Biotech Customized lentivirus for stable overexpression of NBPF3 
                         Customized lentivirus expression plasmids for stable overexpression of NBPF3 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for NBPF3
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat NBPF3
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NBPF3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NBPF3

    Additional mRNA sequence: 

    AF379629.1 AK095602.1 AK098438.1 AK292580.1 AK299840.1 AK314597.1 AL136890.1 AL834330.1 
    AY598326.1 BC024011.2 NR_046176.2 

    17 DOTS entries:

    DT.102844330  DT.100642381  DT.121451686  DT.121451697  DT.121451700  DT.121451706  DT.91661120  DT.95071746 
    DT.121451666  DT.121451691  DT.121451711  DT.121346666  DT.121451670  DT.121451675  DT.121451677  DT.121451710 
    DT.449222 

    24/59 AceView cDNA sequences (see all 59):

    CB148704 AY598326 BG028790 NM_032264 AL136890 AI273699 AA256559 AA768120 
    BX339658 AI378933 BF431439 BE615086 BM971126 BX283934 AL834330 AK095602 
    BX418943 CA428576 AA338107 BE615260 AW401596 BX339657 BV179408 BG028439 

    GeneLoc Exon Structure

    5/15 Alternative Splicing Database (ASD) splice patterns (SP) for NBPF3 (see all 15)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b · 2c ^ 3a · 3b ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b · 9c ^ 10a · 10b ^ 11a · 11b ^
    SP1:                                                  -     -     -                       -     -                                                               
    SP2:                                                        -     -                                                                                             
    SP3:                                                                                                                                                            
    SP4:                                                        -     -                                                                                             
    SP5:                                                  -     -                                                                                                   

    ExUns: 12 ^ 13a · 13b · 13c ^ 14 ^ 15
    SP1:                                    
    SP2:                                    
    SP3:                                    
    SP4:                                    
    SP5:                                    


    ECgene alternative splicing isoforms for NBPF3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NBPF3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    NBPF3 Expression
    About this image


    See NBPF3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NBPF3

    SOURCE GeneReport for Unigene cluster: Hs.325422

    UniProtKB/Swiss-Prot: NBPF3_HUMAN, Q9H094
    Tissue specificity: Expressed in testis and fetal heart, as well as in non small cell lung carcinoma and
    neuroblastoma cell line

        SABiosciences Custom PCR Arrays for NBPF3
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for NBPF3
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat NBPF3
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NBPF3
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NBPF3
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NBPF3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of mammals.

    Orthologs for NBPF3 gene from 1/3 species (see all 3)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    dog
    (Canis familiaris)
    Mammalia --
    --
    34(a)
    possible ortholog
    17(57512543-57515264)


    ENSEMBL Gene Tree for NBPF3 (if available)
    TreeFam Gene Tree for NBPF3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NBPF3 gene
    NBPF62  NBPF202  NBPF82  NBPF162  NBPF92  NBPF42  NBPF112  NBPF242  
    NBPF152  NBPF12  NBPF142  NBPF102  NBPF122  
    18/19 SIMAP similar genes for NBPF3 using alignment to 1 protein entry:     NBPF3_HUMAN(see all similar genes):
    NBPF21    NBPF14    NBPF24    NBPF8    NBPF8P    NBPF10
    LOC101059961    NBPF20    NBPF12    NBPF9    NBPF1    AL592307.2
    NBPF7    NBPF11    NBPF15    NBPF16    NBPF5P    NBPF4

    NBPF3 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for NBPF3
    PGOHUM00000243928


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1296 SNPs in NBPF3 are shown (see all 1296)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1469448171,2
    --21764708(+) TCAAGC/GAATTC 4 -- us2k10--------
    rs1913614301,2
    --21764942(+) CATGCC/TTCATT 4 -- us2k10--------
    rs752411821,2
    F--21765069(+) AAGTGC/TTCACT 4 -- us2k12Minor allele frequency- T:0.04CSA NA 121
    rs764833321,2
    F--21765147(+) TATTTA/CATCCT 4 -- us2k11Minor allele frequency- C:0.03NA 120
    rs66806281,2
    C,F--21765211(+) gaatgG/Aaaact 4 -- us2k111Minor allele frequency- A:0.32NA WA CSA EA 372
    rs66681411,2
    C,F--21765268(+) TAGGGG/CCTGGG 4 -- us2k111Minor allele frequency- C:0.23NA WA CSA EA 373
    rs66808421,2
    C,F--21765428(+) CCTTCG/AGAAGG 4 -- us2k1 tfbs31Minor allele frequency- A:0.50WA 2
    rs1830641541,2
    --21765500(+) GTGTCA/GCCCAC 4 -- us2k10--------
    rs1149278991,2
    --21765531(+) GAACTA/TCTGTG 4 -- us2k10--------
    rs1142034361,2
    --21765532(+) AACTTA/CTGTGT 4 -- us2k10--------

    HapMap Linkage Disequilibrium report for NBPF3 (21766621 - 21811498 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/18 variations for NBPF3 (see all 18):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2661318CNV Deletion23128226
    esv2745042CNV Deletion23290073
    esv2745053CNV Deletion23290073
    esv2456631CNV Deletion19546169
    esv2745064CNV Deletion23290073
    esv1213372CNV Deletion17803354
    esv989724CNV Deletion20482838
    esv2195718CNV Deletion18987734
    esv1311289CNV Deletion17803354
    nsv820559CNV Duplication20802225

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing NBPF3
    DNA2.0 Custom Variant and Variant Library Synthesis for NBPF3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 612992    OMIM disorders: --

    3 diseases for NBPF3:    About MalaCards
    neuroblastoma    non-small cell lung carcinoma    lung cancer


    NBPF3 for disorders           About GeneDecksing

    Genetic Association Database (GAD): NBPF3

    Export disorders for NBPF3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NBPF3 gene, integrated from 9 sources (see all 25):
    (articles sorted by number of sources associating them with NBPF3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution. (PubMed id 16079250)1, 2, 3 Vandepoele K.... van Roy F. (2005)
    2. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2, 3 Wiemann S.... Poustka A. (2001)
    3. Genome-wide association study identifies loci influenc ing concentrations of liver enzymes in plasma. (PubMed id 22001757)1, 4 Chambers J.C....Kooner J.S. (2011)
    4. Common genetic variants associate with serum phosphor us concentration. (PubMed id 20558539)1, 4 Kestenbaum B....Fox C.S. (2010)
    5. Genome-wide association study of vitamin B6, vitamin B12, folate, and homocysteine blood concentrations. (PubMed id 19303062)1, 4 Tanaka T....Ferrucci L. (2009)
    6. Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes. (PubMed id 18940312)1, 4 Yuan X....Mooser V. (2008)
    7. Suppression subtractive hybridization and expression profiling identifies a unique set of genes overexpressed in non-small-cell lung cancer. (PubMed id 15334068)1, 2 Petroziello J.... Carter P. (2004)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    9. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (2012)
    10. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 84224 HGNC: 25076 AceView: AE2 Ensembl:ENSG00000142794 euGenes: HUgn84224
    ECgene: NBPF3 H-InvDB: NBPF3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NBPF3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NBPF3 gene:
    Search GeneIP for patents involving NBPF3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for NBPF3  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for NBPF3  
     OriGene qSTAR qPCR primer pairs in human, mouse for NBPF3   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for NBPF3   OriGene Custom Protein Services for NBPF3  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NBPF3
     QIAGEN SeqTarget long-range PCR primers for resequencing NBPF3
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NBPF3
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NBPF3
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NBPF3
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NBPF3
     GenScript Custom Purified and Recombinant Proteins Services for NBPF3 GenScript cDNA clones with any tag delivered in your preferred vector for NBPF3
     GenScript Custom Assay Services for NBPF3 GenScript Custom Superior Antibodies Services for NBPF3
     GenScript Custom overexpressing Cell Line Services for NBPF3 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in NBPF3 promoter
     Search Chromatin IP Primers for NBPF3
     RT2 qPCR Primer Assay in human, mouse / rat NBPF3
     GNC Network for NBPF3
     SABiosciences Custom PCR Arrays for NBPF3
     Search Tocris compounds for NBPF3
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Biologicals
     Novus Tissue Slides
     Search for Antibodies for NBPF3 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for NBPF3
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for NBPF3
     Antibodies for NBPF3
     ELISAs for NBPF3
     CLIAs for NBPF3
     Search LifeMap BioReagents cell lines for NBPF3
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NBPF3
     SwitchGear 3'UTR luciferase reporter plasmids for NBPF3
     SwitchGear Promoter luciferase reporter plasmids for NBPF3
     ThermoFisher Antibodies for NBPF3
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NBPF3
     inGenious Targeting Laboratory - Custom generated mouse model solutions for NBPF3
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for NBPF3
    Customized:
     lentivirus for stable overexpression of NBPF3
     lentivirus expression plasmids for stable overexpression of NBPF3
     adenovirus for overexpression of NBPF3
     Search LSBio for Antibodies for NBPF3
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      NBPF3 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4