NBPF24 Gene
protein-coding GIFtS: 33
GCID: GC01M147575
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neuroblastoma breakpoint family, member 24
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Aliases
for NBPF24 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Neuroblastoma Breakpoint Family, Member 241 2 |
Export aliases for NBPF24 gene to outside databases |
Summaries
for NBPF24 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for NBPF24 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for NBPF24
Other transcription factors
Search SABiosciences Chromatin IP Primers for NBPF24
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NBPF24 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q21.2 Ensembl cytogenetic band: 1q21.2 HGNC cytogenetic band: 1q21.1NBPF24 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M147575: view genomic region
(about GC identifiers)
Start:
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147,574,428 bp from pter |
End:
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147,624,601 bp from pter |
Size:
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50,174 bases |
Orientation:
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minus strand |
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Proteins
for NBPF24 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: NBPFN_HUMAN, Q5RGN0 (See
protein sequence)Recommended Name: Putative neuroblastoma breakpoint family member 24 Size: 790 amino acids; 90230 Da
Miscellaneous: Encoded by one of the numerous copies of NBPF genes clustered in the p36, p12 and q21 region of thechromosome 1
Caution: Could be the product of a pseudogeneExplore the universe of human proteins at neXtProt for NBPF24: NX_Q5RGN0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q5RGN0
NBPF24 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001095133.2
ENSEMBL proteins: ENSP00000464250 ENSP00000462777 ENSP00000358228 ENSP00000358230
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005737 | cytoplasm |
IEA | -- |
NBPF24 for ontologies About GeneDecksing
NBPF24 Antibody Products:
Assay Products for NBPF24: |
Protein
Domains /
Families
for NBPF24 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NBPF24 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q5RGN0ProtoNet protein and cluster: Q5RGN0 UniProtKB/Swiss-Prot: NBPFN_HUMAN, Q5RGN0Similarity: Belongs to the NBPF familySimilarity: Contains 6 NBPF domains |
Function
for NBPF24 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NBPF24
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NBPF24
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: NBPF24 (NM_001101663) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NBPF24 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NBPF24 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NBPF24 |
|
Pathways & Interactions
for NBPF24 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NBPF24
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for NBPF24 (ENSP000003582284) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for NBPF24 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for NBPF24
Search CenterWatch for drugs/clinical trials and news about NBPF24 / NBPFN
|
Transcripts
for NBPF24 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for NBPF24 gene: NM_001101663.2 8 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000480568(uc001eqa.3 uc010ozx.2 uc009wjr.3 uc001eqb.3 uc001eqc.3 uc010ozy.2 uc001eqd.3 uc001eqe.3 uc001eqf.3 uc001eqg.3)
ENST00000474625 ENST00000369226 ENST00000369228 ENST00000481201 ENST00000475597
ENST00000469181 ENST00000470042
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NBPF24
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NBPF24
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: NBPF24 (NM_001101663) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NBPF24 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NBPF24 |
GeneLoc Exon Structure
|
Expression
for NBPF24 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| NBPF24 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See NBPF24 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NBPF24
SABiosciences Custom PCR Arrays for NBPF24
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NBPF24
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat NBPF24 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NBPF24 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NBPF24 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NBPF24 |
Orthologs
for NBPF24 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for NBPF24 (if available)
TreeFam Gene Tree for NBPF24 (if available) |
Paralogs
for NBPF24 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for NBPF24 gene
- NBPF111 2 NBPF1 NBPF91 2 NBPF121 2 NBPF141 2 NBPF161 2 NBPF151 2 NBPF101 2
- NBPF32 NBPF62 NBPF202 NBPF82 ENSG000002326372 NBPF42
18 SIMAP similar genes for NBPF24 using alignment to 3 protein entries: NBPFN_HUMAN (see all proteins):NBPF21 NBPF15 NBPF16 NBPF20 NBPF8 NBPF1
NBPF14 NBPF11 AL592307.2 NBPF9 LOC101059961 NBPF12
NBPF10 NBPF3 NBPF7 NBPF5 NBPF6 NBPF4
NBPF24 for paralogs About GeneDecksing
|
Genomic Variants
for NBPF24 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for NBPF24 (147574428 - 147624601 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for NBPF24: -- | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for NBPF24 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
NBPF24 for disorders About GeneDecksing
1  disease for NBPF24: About MalaCardsneuroblastoma
Export disorders for NBPF24 gene to outside databases
|
Publications
for NBPF24 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for NBPF24 gene integrated from 9 sources:
(articles sorted by number of sources associating them with NBPF24) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Distinct class of putative 'non-conserved' promoters in humans: comparative studies of alternative promoters of human and mouse genes. (PubMed id 17567985)1 Tsuritani K....Suzuki Y. (2007)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (2006)
- A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution. (PubMed id 16079250)1 Vandepoele K.... van Roy F. (2005)
- Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197)1 Brandenberger R.... Stanton L.W. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for NBPF24 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing NBPF24 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing NBPF24 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NBPF24 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for NBPF24 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for NBPF24 gene:
Search GeneIP for patents involving NBPF24
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for NBPF24 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for NBPF24 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NBPF24 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NBPF24 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for NBPF24 | | OriGene 3'-UTR Clone for NBPF24 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NBPF24 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NBPF24 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for NBPF24 | | OriGene Custom Protein Services for NBPF24 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NBPF24 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NBPF24 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NBPF24 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NBPF24 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NBPF24 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NBPF24 |
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| | | | Search Tocris compounds for NBPF24 |
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 | | | NBPF24 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NBPF24 |
|  |  |  | | | | Search ThermoFisher Antibodies for NBPF24 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NBPF24 |
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