Aliases for NBPF21P Gene
Aliases for NBPF21P Gene
External Ids for NBPF21P Gene
- HGNC: 32001
- Entrez Gene: 205655
- Ensembl: ENSG00000231382
Summaries for NBPF21P Gene
-
This pseudogene on chromosome 3 is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, cognitive disability, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene family contains numerous pseudogenes. [provided by RefSeq, Jun 2013]
GeneCards Summary for NBPF21P Gene
NBPF21P (NBPF Member 21, Pseudogene) is a Pseudogene. Diseases associated with NBPF21P include Neuroblastoma.
Additional gene information for NBPF21P Gene
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NBPF21P Gene
Genomics for NBPF21P Gene
GeneHancer (GH) Regulatory Elements for NBPF21P Gene
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH03I036635 | Enhancer | 0.2 | dbSUPER | 550.8 | +1.7 | 1687 | 0.9 | NBPF21P STAC | ||
GH03I036647 | Enhancer | 1 | ENCODE dbSUPER | 0.4 | -11.5 | -11474 | 3.7 | PKNOX1 ATF1 BATF ZBTB40 RFX5 RCOR1 FOS ATF7 CEBPB ZNF398 | NBPF21P GC03P036685 | |
GH03I036677 | Enhancer | 1.2 | Ensembl ENCODE dbSUPER | 0.3 | -41.3 | -41341 | 4.1 | GTF2E2 JUN TAL1 EBF1 CEBPG BATF ZBTB40 RFX5 FOSL1 ZNF547 | DCLK3 GC03P036685 NBPF21P | |
GH03I036652 | Enhancer | 0.5 | dbSUPER | 0.4 | -15.4 | -15356 | 0.8 | FOSL1 MEIS2 ZNF766 NFE2 ZFX NR2C2 | NBPF21P GC03P036685 | |
GH03I036380 | Promoter/Enhancer | 1.8 | EPDnew Ensembl ENCODE | 0.1 | +256.9 | 256948 | 1.7 | ZSCAN5A KLF1 ZNF449 ZNF133 MAX KLF17 ZNF76 HIC1 E2F1 ZNF335 | STAC NBPF21P |
Regulatory Element Products
Genomic Locations for NBPF21P Gene
- chr3:36,616,006-36,637,797
- (GRCh38/hg38)
- Size:
- 21,792 bases
- Orientation:
- Minus strand
- chr3:36,657,498-36,679,289
- (GRCh37/hg19)
Genomic View for NBPF21P Gene
- Cytogenetic band:
-
- 3p22.2 by Ensembl
- 3p22.2 by Entrez Gene
- 3p22.2 by HGNC


RefSeq DNA sequence for NBPF21P Gene
Proteins for NBPF21P Gene
Post-translational modifications for NBPF21P Gene
Antibody Products
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Protein Products
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No data available for DME Specific Peptides for NBPF21P Gene
Domains & Families for NBPF21P Gene
Gene Families for NBPF21P Gene
- HGNC:
Graphical View of Domain Structure for InterPro Entry
No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for NBPF21P Gene
Function for NBPF21P Gene
Phenotypes From GWAS Catalog for NBPF21P Gene
Animal Model Products
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CRISPR Products
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Vectors and viruses for KO, Activation, Repression, and more
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Clone Products
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- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
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-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NBPF21P Gene
Localization for NBPF21P Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for NBPF21P Gene
Transcripts for NBPF21P Gene
mRNA/cDNA for NBPF21P Gene
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
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Vectors and viruses for KO, Activation, Repression, and more
miRNA Products
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Inhibitory RNA Products
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Clone Products
- GenScript: Custom all cDNA clones Services for NBPF21P
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for NBPF21P
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for NBPF21P Gene
NURSA nuclear receptor signaling pathways regulating expression of NBPF21P Gene:
NBPF21PPrimer Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for NBPF21P Gene
Orthologs for NBPF21P Gene
No data available for Orthologs for NBPF21P Gene
Paralogs for NBPF21P Gene
No data available for Paralogs for NBPF21P Gene
Variants for NBPF21P Gene
Additional Variant Information for NBPF21P Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- NBPF21P
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for NBPF21P Gene
Disorders for NBPF21P Gene
Disorder | Aliases | PubMed IDs |
---|---|---|
neuroblastoma |
|
|
Additional Disease Information for NBPF21P
No data available for UniProtKB/Swiss-Prot and Genatlas for NBPF21P Gene
Publications for NBPF21P Gene
- A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution. (PMID: 16079250) Vandepoele K … van Roy F (Molecular biology and evolution 2005) 2 3 58
- Evolutionary history and genome organization of DUF1220 protein domains. (PMID: 22973535) O'Bleness MS … Sikela JM (G3 (Bethesda, Md.) 2012) 3 58
Products for NBPF21P Gene
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- VectorBuilder custom plasmid, inducible vectors for NBPF21P
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- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneTex for Antibodies for NBPF21P
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Sources for NBPF21P Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
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