NBPF15 Gene
protein-coding GIFtS: 41
GCID: GC01P148555
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neuroblastoma breakpoint family, member 15
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Aliases
for NBPF15 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Neuroblastoma Breakpoint Family, Member 151 2 | | MGC89021 5 | | AB142 | | Neuroblastoma Breakpoint Family Member 152 |
Export aliases for NBPF15 gene to outside databasesPrevious GC identifers: GC01P145341 GC01P146827 GC01P119791 |
Summaries
for NBPF15 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for NBPF15 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004487.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the NBPF15 gene promoter:
GATA-3 Tal-1beta ITF-2 Evi-1 GATA-2 GATA-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for NBPF15
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NBPF15 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q21.2 Ensembl cytogenetic band: 1q21.2 HGNC cytogenetic band: 1q21.1NBPF15 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P148555: view genomic region
(about GC identifiers)
Start:
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148,555,979 bp from pter |
End:
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148,596,267 bp from pter |
Size:
|
40,289 bases |
Orientation:
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plus strand |
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Proteins
for NBPF15 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: NBPFF_HUMAN, Q8N660 (See
protein sequence)Recommended Name: Neuroblastoma breakpoint family member 15 Size: 670 amino acids; 77563 Da
Subcellular location: Cytoplasm (Probable)
Miscellaneous: Encoded by one of the numerous copies of NBPF genes clustered in the p36, p12 and q21 region of thechromosome 1
Secondary accessions: Q3BBV9 Q8IX77Explore the universe of human proteins at neXtProt for NBPF15: NX_Q8N660
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8N660
NBPF15 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001164226.1 NP_775909.2
ENSEMBL proteins: ENSP00000358188 ENSP00000416864
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005737 | cytoplasm |
IEA | -- |
NBPF15 for ontologies About GeneDecksing
NBPF15 Antibody Products:
Assay Products for NBPF15: |
Protein
Domains /
Families
for NBPF15 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NBPF15 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q8N660ProtoNet protein and cluster: Q8N660 UniProtKB/Swiss-Prot: NBPFF_HUMAN, Q8N660Similarity: Belongs to the NBPF familySimilarity: Contains 6 NBPF domains |
Function
for NBPF15 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NBPF15 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NBPF15 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): NBPF15 (NM_173638) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NBPF15 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NBPF15 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NBPF15 |
2 GenomeRNAi human phenotypes for NBPF15:
|
Pathways & Interactions
for NBPF15 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NBPF15
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for NBPF15 (ENSP000003581884) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for NBPF15 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for NBPF15
Search CenterWatch for drugs/clinical trials and news about NBPF15 / NBPFF
|
Transcripts
for NBPF15 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for NBPF15 gene (2 alternative transcripts): NM_001170755.1 NM_173638.3 Unigene Cluster for NBPF15: Neuroblastoma breakpoint family, member 15 Hs.656782 [show with all ESTs]Unigene Representative Sequence: NM_0011707556 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000464336 ENST00000478419 ENST00000488031 ENST00000492711 ENST00000369187
ENST00000442702(uc001esb.2 uc001esc.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NBPF15 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NBPF15 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): NBPF15 (NM_173638) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NBPF15 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NBPF15 |
Additional cDNA sequence: AF379630.1 AK097180.1 AK290142.1 AK290302.1 AK299360.1 AY894566.1 BC023087.1 XR_159175.1 XR_171213.1 24/42 DOTS entries (see all 42): DT.100058829 DT.100059221 DT.87078282 DT.92411509 DT.100800519 DT.95247186 DT.87017630 DT.99963054 DT.305473 DT.100861446 DT.95230911 DT.100646648 DT.121460520 DT.121460586 DT.95301339 DT.100807097 DT.121460210 DT.121460287 DT.121460342 DT.121460601 DT.121644796 DT.95296607 DT.97759819 DT.100059352 24/149 AceView cDNA sequences (see all 149): BX280725 BU734684 BQ215282 AI654244 AL556016 BV200708 BM738280 BM796852 AI003102 BV194613 BG121940 AW196804 BU170083 BM477098 CD172082 CA941244 N69326 CA416083 BU632535 W92875 BU581490 AI080172 BM738462 BE841124
GeneLoc Exon Structure
|
Expression
for NBPF15 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| NBPF15 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATTAAATTCA
About this image
See NBPF15 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NBPF15
SOURCE GeneReport for Unigene cluster: Hs.656782
UniProtKB/Swiss-Prot: NBPFF_HUMAN, Q8N660Tissue specificity: Ubiquitously expressed with a higher expression observed in breast and liver. Also expressed inneuroblastoma cell line
SABiosciences Custom PCR Arrays for NBPF15
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NBPF15
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat NBPF15 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NBPF15 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NBPF15 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NBPF15 |
Orthologs
for NBPF15 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for NBPF15 (if available)
TreeFam Gene Tree for NBPF15 (if available) |
Paralogs
for NBPF15 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for NBPF15 gene
- NBPF161 2 NBPF91 2 NBPF121 2 NBPF1 NBPF141 2 NBPF241 2 NBPF111 2 NBPF101 2
- NBPF32 NBPF62 NBPF202 NBPF82 ENSG000002326372 NBPF42
18 SIMAP similar genes for NBPF15 using alignment to 1 protein entry: NBPFF_HUMAN:NBPF16 NBPF21 NBPF8 AL592307.2 NBPF1 NBPF14
NBPF20 NBPF24 NBPF12 NBPF10 NBPF11 LOC101059961
NBPF9 NBPF7 NBPF5 NBPF3 NBPF4 NBPF6
NBPF15 for paralogs About GeneDecksing
|
Genomic Variants
for NBPF15 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for NBPF15 (148555979 - 148596267 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 18 variations for NBPF15
15/18 CNVs (see all 18): 48119 8924 6785 48120 2326 31658 30427 38856 34420 8329 48118 3313 30428 8328 69988 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NBPF15 |
|
Disorders
/ Diseases
for NBPF15 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
NBPF15 for disorders About GeneDecksing
OMIM gene information: 610414
OMIM disorders: --
1  disease for NBPF15: About MalaCardsneuroblastoma
Export disorders for NBPF15 gene to outside databases
|
Publications
for NBPF15 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for NBPF15 gene integrated from 9 sources:
(articles sorted by number of sources associating them with NBPF15) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution. (PubMed id 16079250)1, 2, 3 Vandepoele K.... van Roy F. (2005)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Genome-wide association study implicates PARD3B-based AIDS restriction. (PubMed id 21502085)1 Troyer J.L....O'Brien S.J. (2011)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for NBPF15 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing NBPF15 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing NBPF15 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NBPF15 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for NBPF15 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for NBPF15 gene:
Search GeneIP for patents involving NBPF15
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for NBPF15 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
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| |  |  |  |  | | | | |
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| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NBPF15 |
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| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NBPF15 |
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