NBPF14 Gene
protein-coding GIFtS: 41
GCID: GC01M148003 (predicted)
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|
neuroblastoma breakpoint family, member 14
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Aliases
for NBPF14 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Neuroblastoma Breakpoint Family, Member 141 2 | | DJ328E19.C1.11 2 | | AE52 | | NBPF2 | | Neuroblastoma Breakpoint Family Member 142 |
Export aliases for NBPF14 gene to outside databasesPrevious GC identifers: GC01M145120 GC01M146470 |
Summaries
for NBPF14 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for NBPF14 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_167185.1
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for NBPF14
Other transcription factors
Search SABiosciences Chromatin IP Primers for NBPF14
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NBPF14 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q21.1 Ensembl cytogenetic band: 1q21.2 HGNC cytogenetic band: 1q21.1NBPF14 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M148003: view genomic region
(about GC identifiers)
Start:
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148,003,642 bp from pter |
End:
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148,025,863 bp from pter |
Size:
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22,222 bases |
Orientation:
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minus strand |
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Proteins
for NBPF14 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: NBPFE_HUMAN, Q5TI25 (See
protein sequence)Recommended Name: Neuroblastoma breakpoint family member 14 Size: 921 amino acids; 105853 Da
Subcellular location: Cytoplasm (Probable)
Miscellaneous: Encoded by one of the numerous copies of NBPF genes clustered in the p36, p12 and q21 region of thechromosome 1
Sequence caution: Sequence=CAI20179.1; Type=Erroneous initiation; Sequence=CAI20180.1; Type=Erroneous gene modelprediction; Sequence=CAI20181.1; Type=Erroneous gene model prediction; Sequence=CAI20182.1; Type=Erroneous gene modelprediction; Sequence=CAI20183.1; Type=Erroneous gene model prediction; Sequence=CAI20184.1; Type=Erroneous gene modelprediction; Sequence=CAI20185.1; Type=Erroneous gene model prediction; Sequence=CAI20186.1; Type=Erroneous gene modelprediction;
Secondary accessions: Q5TI23 Q8IX76 Q9UJI9Explore the universe of human proteins at neXtProt for NBPF14: NX_Q5TI25
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q5TI25
NBPF14 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_056198.1
ENSEMBL proteins: ENSP00000309907 ENSP00000397707 ENSP00000403155 ENSP00000411975 ENSP00000416860 ENSP00000410336 ENSP00000376698 ENSP00000396201 ENSP00000358221 ENSP00000358375 ENSP00000387934 ENSP00000402144
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005737 | cytoplasm |
IEA | -- |
NBPF14 for ontologies About GeneDecksing
NBPF14 Antibody Products:
Assay Products for NBPF14: |
Protein
Domains /
Families
for NBPF14 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NBPF14 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q5TI25ProtoNet protein and cluster: Q5TI25 UniProtKB/Swiss-Prot: NBPFE_HUMAN, Q5TI25Similarity: Belongs to the NBPF familySimilarity: Contains 10 NBPF domains |
Function
for NBPF14 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NBPF14
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NBPF14
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: NBPF14 (NM_015383) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NBPF14 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat NBPF14 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NBPF14 |
|
Pathways & Interactions
for NBPF14 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NBPF14
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
3 Interacting proteins for NBPF14 (Q5TI253 ENSP000003582214) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for NBPF14 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for NBPF14
Search CenterWatch for drugs/clinical trials and news about NBPF14 / NBPFE
|
Transcripts
for NBPF14 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for NBPF14 gene: NM_015383.1 Unigene Cluster for NBPF14: Neuroblastoma breakpoint family, member 14 Hs.744720 Unigene Representative Sequence: AF37962212 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000310701(uc001eqq.3 uc021ovz.1 uc021owa.1) ENST00000444640(uc021owd.1)
ENST00000431121 ENST00000436356 ENST00000448574 ENST00000458135 ENST00000392972
ENST00000426874 ENST00000369219(uc010pad.1 uc021owc.1 uc021owe.1)
ENST00000369368 ENST00000415551 ENST00000434489
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NBPF14
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NBPF14
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: NBPF14 (NM_015383) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NBPF14 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat NBPF14 |
Additional cDNA sequence: AF379622.1 1 DOTS entry: DT.121436046 24/219 AceView cDNA sequences (see all 219): AA478452 BM665124 D31148 AA447033 BM454751 AA577102 AI373099 AI671614 BV180621 AW675613 AA322028 BI917240 BX646450 AI149616 BX464746 BQ029514 W95853 BF793347 BG180222 AW474946 BG288809 AF379621 AA954844 BE274740
GeneLoc Exon Structure
|
Expression
for NBPF14 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| NBPF14 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See NBPF14 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NBPF14
SOURCE GeneReport for Unigene cluster: Hs.744720
UniProtKB/Swiss-Prot: NBPFE_HUMAN, Q5TI25Tissue specificity: Expressed in spleen and fetal liver
SABiosciences Custom PCR Arrays for NBPF14
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NBPF14
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat NBPF14 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NBPF14 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NBPF14 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NBPF14 |
Orthologs
for NBPF14 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for NBPF14 (if available)
TreeFam Gene Tree for NBPF14 (if available) |
Paralogs
for NBPF14 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for NBPF14 gene
- NBPF91 2 NBPF161 2 NBPF151 2 NBPF121 2 NBPF1 NBPF241 2 NBPF111 2 NBPF101 2
- NBPF32 NBPF62 NBPF202 NBPF82 ENSG000002326372 NBPF42
18 SIMAP similar genes for NBPF14 using alignment to 6 protein entries: NBPFE_HUMAN (see all proteins):NBPF21 NBPF8 NBPF1 AL592307.2 NBPF15 NBPF16
NBPF20 NBPF24 NBPF12 NBPF9 LOC101059961 NBPF11
NBPF10 NBPF3 NBPF7 NBPF5 NBPF6 NBPF4
NBPF14 for paralogs About GeneDecksing
|
Genomic Variants
for NBPF14 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for NBPF14 (148003642 - 148025863 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 16 variations for NBPF14
15/16 CNVs (see all 16): 48119 8924 3313 48120 2326 0390 69965 8328 34707 48117 69963 34706 30426 34420 8329 | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for NBPF14 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
NBPF14 for disorders About GeneDecksing
OMIM gene information: 614003
OMIM disorders: --
1  disease for NBPF14: About MalaCardsneuroblastoma
Export disorders for NBPF14 gene to outside databases
|
Publications
for NBPF14 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for NBPF14 gene, integrated from 9 sources (see all 36):
(articles sorted by number of sources associating them with NBPF14) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution. (PubMed id 16079250)1, 2, 3 Vandepoele K.... van Roy F. (2005)
- Large-scale concatenation cDNA sequencing. (PubMed id 9110174)1, 3 Yu W.... Gibbs R.A. (1997)
- A "double adaptor" method for improved shotgun library construction. (PubMed id 8619474)1, 3 Andersson B.... Gibbs R.A. (1996)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Genome-wide association study implicates PARD3B-based AIDS restriction. (PubMed id 21502085)1 Troyer J.L....O'Brien S.J. (2011)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
- Differentiation in cultured limbal epithelium as defined by keratin expression. (PubMed id 1718924)9 Kiritoshi A....Thoft R.A. (1991)
- [A pilot study on transdifferentiation of skin stem cell in reconstructing corneal epithelium] (PubMed id 15200889)9 Huang B....Guo F.F. (2004)
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External Searches for NBPF14 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing NBPF14 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing NBPF14 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NBPF14 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for NBPF14 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for NBPF14 gene:
Search GeneIP for patents involving NBPF14
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for NBPF14 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | Browse OriGene 29mer shRNA kits in GFP-retroviral vector | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NBPF14 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for NBPF14 | | OriGene 3'-UTR Clone for NBPF14 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NBPF14 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NBPF14 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for NBPF14 | | OriGene Custom Protein Services for NBPF14 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NBPF14 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NBPF14 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NBPF14 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NBPF14 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NBPF14 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NBPF14 |
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| |  |  |  |  | | | | |
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 | | | NBPF14 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NBPF14 |
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| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat NBPF14 |
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