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Aliases for NBEAP1 Gene

Aliases for NBEAP1 Gene

  • Neurobeachin Pseudogene 1 2 3 4 5
  • B-Cell CLL/Lymphoma 8 2 3
  • BCL8A 3 4
  • BCL8 3 4

External Ids for NBEAP1 Gene

Previous HGNC Symbols for NBEAP1 Gene

  • BCL8

Previous GeneCards Identifiers for NBEAP1 Gene

  • GC15M020875

Summaries for NBEAP1 Gene

GeneCards Summary for NBEAP1 Gene

NBEAP1 (Neurobeachin Pseudogene 1) is a Pseudogene.

Additional gene information for NBEAP1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NBEAP1 Gene

Genomics for NBEAP1 Gene

Regulatory Elements for NBEAP1 Gene


Promoters for NBEAP1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000073936 150 1199 NRF1

Genomic Location for NBEAP1 Gene

Chromosome:
15
Start:
20,657,638 bp from pter
End:
20,756,151 bp from pter
Size:
98,514 bases
Orientation:
Minus strand

Genomic View for NBEAP1 Gene

Genes around NBEAP1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NBEAP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NBEAP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NBEAP1 Gene

Proteins for NBEAP1 Gene

  • Protein details for NBEAP1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0C6P0-BCL8_HUMAN
    Recommended name:
    Putative protein BCL8
    Protein Accession:
    P0C6P0

    Protein attributes for NBEAP1 Gene

    Size:
    100 amino acids
    Molecular mass:
    11233 Da
    Quaternary structure:
    No Data Available

neXtProt entry for NBEAP1 Gene

Post-translational modifications for NBEAP1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for NBEAP1 Gene

Domains & Families for NBEAP1 Gene

Protein Domains for NBEAP1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for NBEAP1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with NBEAP1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for NBEAP1 Gene

Function for NBEAP1 Gene

Animal Model Products

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for NBEAP1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NBEAP1 Gene

Localization for NBEAP1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for NBEAP1 Gene

Pathways & Interactions for NBEAP1 Gene

SuperPathways for NBEAP1 Gene

No Data Available

Interacting Proteins for NBEAP1 Gene

Gene Ontology (GO) - Biological Process for NBEAP1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for NBEAP1 Gene

Drugs & Compounds for NBEAP1 Gene

No Compound Related Data Available

Transcripts for NBEAP1 Gene

mRNA/cDNA for NBEAP1 Gene

(4) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for NBEAP1 Gene

Neurobeachin pseudogene 1:
Representative Sequences:

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for NBEAP1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for NBEAP1 Gene

No ASD Table

Relevant External Links for NBEAP1 Gene

GeneLoc Exon Structure for
NBEAP1
ECgene alternative splicing isoforms for
NBEAP1

Expression for NBEAP1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for NBEAP1 Gene

mRNA differential expression in normal tissues according to GTEx for NBEAP1 Gene

This gene is overexpressed in Testis (x12.8).

NURSA nuclear receptor signaling pathways regulating expression of NBEAP1 Gene:

NBEAP1

SOURCE GeneReport for Unigene cluster for NBEAP1 Gene:

Hs.657985

mRNA Expression by UniProt/SwissProt for NBEAP1 Gene:

P0C6P0-BCL8_HUMAN
Tissue specificity: Expressed in prostate and testis.
genes like me logo Genes that share expression patterns with NBEAP1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for NBEAP1 Gene

Orthologs for NBEAP1 Gene

Evolution for NBEAP1 Gene

ENSEMBL:
Gene Tree for NBEAP1 (if available)
TreeFam:
Gene Tree for NBEAP1 (if available)

No data available for Orthologs for NBEAP1 Gene

Paralogs for NBEAP1 Gene

(2) SIMAP similar genes for NBEAP1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with NBEAP1: view

No data available for Paralogs for NBEAP1 Gene

Variants for NBEAP1 Gene

Sequence variations from dbSNP and Humsavar for NBEAP1 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs1000585696 -- 20,736,134(+) ACAGA(C/T)TATTC intron-variant
rs1001039638 -- 20,738,392(+) AAAGC(C/T)AAAAG intron-variant
rs1001643999 -- 20,749,318(+) TTCTC(C/T)GTGCG intron-variant
rs1001989909 -- 20,746,880(+) GACCT(C/T)GTGAT intron-variant
rs1002414740 -- 20,678,508(+) AATTG(A/G)TAAAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for NBEAP1 Gene

Variant ID Type Subtype PubMed ID
dgv1360e59 CNV duplication 20981092
dgv1n1 OTHER inversion 15895083
dgv2174n100 CNV gain 25217958
dgv2175n100 CNV gain 25217958
dgv2179n100 CNV gain 25217958
dgv2181n100 CNV gain 25217958
dgv2182n100 CNV gain 25217958
dgv2183n100 CNV loss 25217958
dgv2186n100 CNV gain+loss 25217958
dgv2187n100 CNV gain 25217958
dgv2188n100 CNV loss 25217958
dgv2189n100 CNV gain+loss 25217958
dgv2190n100 CNV gain+loss 25217958
dgv2191n100 CNV gain+loss 25217958
dgv2192n100 CNV loss 25217958
dgv2193n100 CNV gain+loss 25217958
dgv2195n100 CNV loss 25217958
dgv2201n100 CNV gain 25217958
dgv2207n100 CNV loss 25217958
dgv2208n100 CNV gain 25217958
dgv2209n100 CNV gain+loss 25217958
dgv2210n100 CNV gain 25217958
dgv2211n100 CNV loss 25217958
dgv2212n100 CNV gain 25217958
dgv2213n100 CNV loss 25217958
dgv2214n100 CNV gain 25217958
dgv2222n100 CNV gain+loss 25217958
dgv2228n100 CNV gain 25217958
dgv2231n100 CNV gain+loss 25217958
dgv2232n100 CNV loss 25217958
dgv2233n100 CNV loss 25217958
dgv2237n100 CNV gain 25217958
dgv2238n100 CNV gain 25217958
dgv2244n100 CNV loss 25217958
dgv2245n100 CNV loss 25217958
dgv2246n100 CNV gain+loss 25217958
dgv2250n100 CNV gain+loss 25217958
dgv2257n100 CNV gain 25217958
dgv2278n100 CNV gain 25217958
dgv2279n100 CNV loss 25217958
dgv2280n100 CNV loss 25217958
dgv2281n100 CNV gain+loss 25217958
dgv2282n100 CNV gain 25217958
dgv2283n100 CNV gain 25217958
dgv2284n100 CNV gain 25217958
dgv2287n100 CNV gain+loss 25217958
dgv2288n100 CNV gain 25217958
dgv2289n100 CNV loss 25217958
dgv2290n100 CNV gain+loss 25217958
dgv2291n100 CNV loss 25217958
dgv2292n100 CNV loss 25217958
dgv2293n100 CNV loss 25217958
dgv2294n100 CNV loss 25217958
dgv2295n100 CNV loss 25217958
dgv2296n100 CNV loss 25217958
dgv2297n100 CNV gain 25217958
dgv2298n100 CNV gain+loss 25217958
dgv2300n100 CNV loss 25217958
dgv2301n100 CNV loss 25217958
dgv2304n100 CNV gain 25217958
dgv2308n100 CNV loss 25217958
dgv2309n100 CNV gain 25217958
dgv2310n100 CNV gain 25217958
dgv2311n100 CNV loss 25217958
dgv2312n100 CNV gain 25217958
dgv2313n100 CNV loss 25217958
dgv2314n100 CNV loss 25217958
dgv2315n100 CNV gain 25217958
dgv2316n100 CNV loss 25217958
dgv2317n100 CNV gain 25217958
dgv2318n100 CNV loss 25217958
dgv2319n100 CNV loss 25217958
dgv2320n100 CNV loss 25217958
dgv2321n100 CNV gain+loss 25217958
dgv4162n54 CNV loss 21841781
dgv4164n54 CNV loss 21841781
dgv4166n54 CNV gain 21841781
dgv4174n54 CNV loss 21841781
dgv4180n54 CNV gain 21841781
dgv4182n54 CNV loss 21841781
dgv4183n54 CNV loss 21841781
dgv418n67 CNV gain 20364138
dgv4194n54 CNV loss 21841781
dgv4210n54 CNV gain 21841781
dgv4211n54 CNV gain 21841781
dgv4213n54 CNV loss 21841781
dgv4214n54 CNV loss 21841781
dgv4217n54 CNV loss 21841781
dgv4220n54 CNV gain+loss 21841781
dgv4221n54 CNV loss 21841781
dgv4222n54 CNV gain 21841781
dgv4223n54 CNV gain+loss 21841781
dgv4224n54 CNV loss 21841781
dgv4225n54 CNV loss 21841781
dgv4226n54 CNV loss 21841781
dgv4230n54 CNV loss 21841781
dgv4231n54 CNV gain 21841781
dgv43n16 CNV insertion 17901297
dgv91e55 CNV gain 17911159
dgv92e55 CNV gain 17911159
dgv93e55 CNV gain 17911159
dgv95e55 CNV loss 17911159
dgv96e55 CNV loss 17911159
esv1004259 OTHER inversion 20482838
esv1033058 CNV insertion 17803354
esv21579 CNV gain+loss 19812545
esv2664547 CNV deletion 23128226
esv2751488 CNV loss 17911159
esv29956 CNV loss 18421352
esv33051 CNV gain+loss 17666407
esv3395938 CNV duplication 20981092
esv3552169 CNV deletion 23714750
esv3584679 CNV loss 24956385
esv3584810 CNV gain 24956385
esv3584832 CNV gain 24956385
esv3584854 CNV gain 24956385
esv3584865 CNV gain 24956385
esv3892595 CNV gain+loss 25118596
esv3892607 CNV gain 25118596
esv3892609 CNV gain 25118596
esv988919 CNV loss 20482838
esv998148 CNV insertion 20482838
nsv1037076 CNV gain 25217958
nsv1043213 CNV gain+loss 25217958
nsv1044760 CNV gain 25217958
nsv1051753 CNV loss 25217958
nsv1075468 CNV duplication 25765185
nsv1075876 CNV duplication 25765185
nsv1077792 CNV duplication 25765185
nsv1110247 CNV duplication 24896259
nsv1110248 CNV duplication 24896259
nsv1128709 CNV duplication 24896259
nsv1132394 CNV duplication 24896259
nsv1141250 CNV duplication 24896259
nsv1146032 CNV duplication 26484159
nsv1147293 CNV duplication 26484159
nsv1149540 CNV duplication 26484159
nsv1160218 CNV duplication 26073780
nsv1456 CNV insertion 18451855
nsv428296 CNV gain+loss 18775914
nsv433281 CNV loss 18776910
nsv435662 CNV deletion 17901297
nsv436198 CNV deletion 17901297
nsv469642 CNV gain 16826518
nsv471537 CNV gain 19718026
nsv471675 CNV gain+loss 15918152
nsv511040 OTHER inversion 20534489
nsv513752 CNV insertion 21212237
nsv514764 CNV gain 21397061
nsv567312 CNV gain 21841781
nsv567487 CNV gain+loss 21841781
nsv7260 OTHER inversion 18451855
nsv819612 CNV gain 19587683
nsv819770 CNV gain 19587683
nsv821678 CNV loss 15273396
nsv827221 CNV gain 20364138
nsv832911 CNV gain+loss 17160897
nsv832915 CNV gain+loss 17160897
nsv9179 CNV gain+loss 18304495
nsv952315 CNV duplication 24416366
nsv952317 CNV duplication 24416366
nsv976879 CNV duplication 23825009

Relevant External Links for NBEAP1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
NBEAP1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for NBEAP1 Gene

Disorders for NBEAP1 Gene

UniProtKB/Swiss-Prot

BCL8_HUMAN
  • Note=A chromosomal aberration involving BCL8 has been observed in diffuse large cell lymphoma (DLCL). Translocation t(14;15)(q32;q11-q13). The BCL8/IgH translocation leaves the coding region of BCL8 intact, but may have pathogenic effects due to alterations in the expression level of BCL8.

Relevant External Links for NBEAP1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
NBEAP1

No disorders were found for NBEAP1 Gene.

No data available for MalaCards and Genatlas for NBEAP1 Gene

Publications for NBEAP1 Gene

  1. BCL8, a novel gene involved in translocations affecting band 15q11-13 in diffuse large-cell lymphoma. (PMID: 9159141) Dyomin VG … Chaganti RS (Proceedings of the National Academy of Sciences of the United States of America 1997) 2 3 4 60
  2. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody MC … Nusbaum C (Nature 2006) 3 4 60
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  4. BCL8 is a novel, evolutionarily conserved human gene family encoding proteins with presumptive protein kinase A anchoring function. (PMID: 12160729) Dyomin VG … Chaganti RS (Genomics 2002) 3 4 60
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 60

Products for NBEAP1 Gene

Sources for NBEAP1 Gene

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