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NBAS Gene

protein-coding   GIFtS: 52
GCID: GC02M015224

Neuroblastoma Amplified Sequence

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Neuroblastoma Amplified Sequence1 2     NAG/FAM49A Fusion2
NAG2 3 5     Neuroblastoma-Amplified Sequence2
Neuroblastoma-Amplified Gene Protein2 3     EC 1.1.1.948
SOPH2 5     EC 1.2.1.598
NAG/BC035112 Fusion2     

External Ids:    HGNC: 156251   Entrez Gene: 515942   Ensembl: ENSG000001517797   OMIM: 6080255   UniProtKB: A2RRP13   

Export aliases for NBAS gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for NBAS Gene:
This gene encodes a protein with two leucine zipper domains, a ribosomal protein S14 signature domain and a Sec39
like domain. The protein is thought to be involved in Golgi-to-ER transport. Mutations in this gene are
associated with short stature, optic nerve atrophy, and Pelger-Huet anomaly. (provided by RefSeq, Oct 2012)

GeneCards Summary for NBAS Gene:
NBAS (neuroblastoma amplified sequence) is a protein-coding gene. Diseases associated with NBAS include short stature, optic nerve atrophy, and pelger-huet anomaly, and pelger-huet anomaly.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000002.12  NC_018913.2  NT_005334.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the NBAS gene promoter:
         Nkx3-1   USF1   USF2   Nkx3-1 v1   USF-1:USF-2   POU3F2   GATA-1   Nkx3-1 v2   USF-1   Nkx3-1 v3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNBAS promoter sequence
   Search Chromatin IP Primers for NBAS

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NBAS


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p24   Ensembl cytogenetic band:  2p24.3   HGNC cytogenetic band: 2p24.3

NBAS Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NBAS gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M015224:  view genomic region     (about GC identifiers)

Start:
15,307,032 bp from pter      End:
15,701,454 bp from pter
Size:
394,423 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: NBAS_HUMAN, A2RRP1 (See protein sequence)
Recommended Name: Neuroblastoma-amplified sequence  
Size: 2371 amino acids; 268571 Da
Sequence caution: Sequence=AAD18133.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=AAD18133.1; Type=Erroneous termination; Positions=2372; Note=Translated as stop; Sequence=CAB43382.1;
Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: O95790 Q2VPJ7 Q53TK6 Q86V39 Q8NFY8 Q9Y3W5
Alternative splicing: 2 isoforms:  A2RRP1-1   A2RRP1-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NBAS: NX_A2RRP1

Explore proteomics data for NBAS at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys265, Lys284, Lys673, Lys799, Lys1246, Lys1452, Lys1667
  • Modification sites at PhosphoSitePlus
  • 2 DME Specific Peptides for NBAS (A2RRP1)
     DAAKELL  VPENVDA 


    See NBAS Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_056993.2  
    ENSEMBL proteins: 
     ENSP00000281513   ENSP00000392421   ENSP00000390920   ENSP00000398411   ENSP00000403119  
     ENSP00000396501   ENSP00000391476   ENSP00000402458   ENSP00000413201  

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    Novus Biologicals NBAS Protein
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    Cloud-Clone Corp. CLIAs for NBAS


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR013244 Sec39
     IPR015943 WD40/YVTN_repeat-like_dom
     IPR011044 Quino_amine_DH_bsu

    Graphical View of Domain Structure for InterPro Entry A2RRP1

    ProtoNet protein and cluster: A2RRP1

    UniProtKB/Swiss-Prot: NBAS_HUMAN, A2RRP1
    Similarity: Contains 2 WD repeats


    NBAS for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Enzyme Numbers (IUBMB): EC 1.1.1.942 EC 1.2.1.592

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    NBAS for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for NBAS:
     Increased gamma-H2AX phosphory 

         1 MGI phenotypic allele for Nbas (no phenotypes)

    NBAS for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NBAS
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for NBAS

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NBAS
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NBAS

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    SwitchGear 3'UTR luciferase reporter plasmidNBAS 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat NBAS

    Gene Editing
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NBAS

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NBAS


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NBAS_HUMAN, A2RRP1: Cytoplasm
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    golgi apparatus1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--

    NBAS for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NBAS
    Interactions:

        Search GeneGlobe Interaction Network for NBAS

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    Selected Interacting proteins for NBAS (A2RRP12, 3 ENSP000002815134) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    OLFM2O958972, 3MINT-63329 I2D: score=4 
    TLE4Q047273I2D: score=2 
    RINT1ENSP000002577004STRING: ENSP00000257700
    ZW10ENSP000002001354STRING: ENSP00000200135
    NUF2ENSP000002714524STRING: ENSP00000271452
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000956nuclear-transcribed mRNA catabolic process IMP--
    GO:2000623negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IMP--

    NBAS for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NBAS



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for NBAS gene: 
    NM_015909.3  

    Unigene Cluster for NBAS:

    Neuroblastoma amplified sequence
    Hs.467759  [show with all ESTs]
    Unigene Representative Sequence: NM_015909
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000281513(uc002rcc.1 uc002rcd.1) ENST00000417461 ENST00000433283
    ENST00000442506 ENST00000485694 ENST00000423602 ENST00000441755 ENST00000429842
    ENST00000427792 ENST00000441750(uc002rcb.1 uc010exl.1)
    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidNBAS 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat NBAS
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    Primer
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    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat NBAS
      QuantiTect SYBR Green Assays in human, mouse, rat NBAS
      QuantiFast Probe-based Assays in human, mouse, rat NBAS

    Additional mRNA sequence: 

    AB621813.1 AF056195.1 AF388385.1 AK057915.1 AK097726.1 AK126995.1 AL050281.1 AL832774.1 
    AL833270.1 BC040345.1 BC051792.1 BC108693.1 BC131735.1 HM243530.1 HM243531.1 HM243532.1 
    NR_052013.2 

    21 DOTS entries:

    DT.100036969  DT.116378  DT.100792113  DT.92444647  DT.95272029  DT.121032857  DT.87016313  DT.100792110 
    DT.208502  DT.40108630  DT.92033401  DT.92444657  DT.403952  DT.91724239  DT.95272031  DT.97781493 
    DT.100642571  DT.121033018  DT.208503  DT.75145785  DT.97762091 

    Selected AceView cDNA sequences (see all 280):

    BU188118 L43349 AA703606 Z38290 AK057915 AI631427 BQ008181 AI198165 
    BU181487 AI420316 BF972877 AW453025 BU632388 BM471503 AA236868 AI884956 
    BG474548 CB135921 BQ017172 AL832774 BM712322 BQ921702 BQ927383 AL050281 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for NBAS    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^ 25 ^
    SP1:                          -     -                                                                                                                           
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 26 ^ 27 ^ 28 ^ 29 ^ 30 ^ 31a · 31b ^ 32
    SP1:                                -               
    SP2:                                -               
    SP3:              -                 -               
    SP4:                                -     -         
    SP5:                                                


    ECgene alternative splicing isoforms for NBAS

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NBAS expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTTCCAACAA
    NBAS Expression
    About this image

    NBAS Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NBAS Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.467759

    UniProtKB/Swiss-Prot: NBAS_HUMAN, A2RRP1
    Tissue specificity: Broadly expressed, with highest levels in heart and skeletal muscle, and lowest levels in
    liver, small intestine and thymus. Well expressed in retinal ganglion cells, epidermal skin cells, and
    leukocytes. Up-regulated together with N-myc in some neuroblastoma cell lines

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for NBAS gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nbas1 , 5 neuroblastoma amplified sequence1, 5 84.56(n)1
    85.91(a)1
      12 (6.45 cM)5
    711691  NM_027706.11  NP_081982.11 
     132691275 
    chicken
    (Gallus gallus)
    Aves NBAS1 neuroblastoma amplified sequence 73.75(n)
    74.53(a)
      421947  XM_419959.4  XP_419959.3 
    lizard
    (Anolis carolinensis)
    Reptilia NBAS6
    neuroblastoma amplified sequence
    73(a)
    1 ↔ 1
    1(144564424-144751417)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia nbas1 neuroblastoma amplified sequence 68.64(n)
    69.18(a)
      100489377  XM_002941372.2  XP_002941418.2 
    zebrafish
    (Danio rerio)
    Actinopterygii CF998629.12   -- 71.67(n)    CF998629.1 
    worm
    (Caenorhabditis elegans)
    Secernentea smgl-16
    Protein SMGL-1 (smgl-1) mRNA, complete cds
    20(a)
    1 ↔ 1
    I(7918442-7926337) WBGene00008990


    ENSEMBL Gene Tree for NBAS (if available)
    TreeFam Gene Tree for NBAS (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for NBAS gene
    1 SIMAP similar gene for NBAS using alignment to 10 protein entries:     NBAS_HUMAN (see all proteins):
    NAG

    NBAS for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for NBAS
    PGOHUM00000246079


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NBAS (see all 8388)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0689574
    Short stature, optic nerve atrophy, and Pelger-Huet anomaly (SOPH)4--see VAR_0689572 R H mis40--------
    rs741732421,2
    C--15211116(+) TGGCCA/GGGCGG 2 -- int11Minor allele frequency- G:0.00NA 2
    rs1451343051,2
    --15274556(+) TTCATA/GTACTG 2 -- ds50010--------
    rs1851686841,2
    C--15274562(+) TACTGC/TGACAC 2 -- ds50010--------
    rs116743371,2
    C,F,H--15274664(+) CTTTAC/TGAGAC 2 -- ds50015Minor allele frequency- T:0.01NS EA NA 424
    rs101894501,2
    C,F,A,H--15274705(+) TAGACT/ATAGGT 2 -- ds500132Minor allele frequency- A:0.30NS EA NA WA CSA 3196
    rs1896377291,2
    --15274806(+) TGACCG/TCCAGG 2 -- ds50010--------
    rs22413481,2
    C,F,A,H--15274856(+) CACCAG/CCACAT 2 -- ds500126Minor allele frequency- C:0.48EA NA NS WA CSA 2915
    rs1424939561,2
    --15274970(+) CAATAA/TGAAAA 2 -- ds50010--------
    rs1430162381,2
    --15275091(+) GGCAGA/GTACAC 2 -- nc-transcript-variantut310--------

    HapMap Linkage Disequilibrium report for NBAS (15307032 - 15557032 bp, first 250kb of NBAS)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for NBAS (see all 12):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2719726CNV Deletion23290073
    esv1330669CNV Insertion17803354
    esv2617488CNV Insertion19546169
    esv1243706CNV Insertion17803354
    esv274491CNV Insertion20981092
    esv268567CNV Insertion20981092
    dgv612n67CNV Gain20364138
    nsv819028CNV Gain19587683
    esv6386CNV Gain19470904
    dgv613n67CNV Gain20364138

    Human Gene Mutation Database (HGMD): NBAS
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NBAS
    DNA2.0 Custom Variant and Variant Library Synthesis for NBAS

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 608025   
    OMIM disorders: 614800  
    UniProtKB/Swiss-Prot: NBAS_HUMAN, A2RRP1
  • Short stature, optic nerve atrophy, and Pelger-Huet anomaly (SOPH) [MIM:614800]: An autosomal recessive
    syndrome characterized by severe postnatal growth retardation, facial dysmorphism with senile face, small hands
    and feet, normal intelligence, abnormal nuclear shape in neutrophil granulocytes (Pelger-Huet anomaly), and optic
    atrophy with loss of visual acuity and color vision. Note=The disease is caused by mutations affecting the gene
    represented in this entry

  • 16 diseases for NBAS:    
    About MalaCards
    short stature, optic nerve atrophy, and pelger-huet anomaly    pelger-huet anomaly    mirror-image polydactyly    short stature
    neuroblastoma    polydactyly    conduct disorder    optic atrophy
    medulloblastoma    myelodysplastic syndromes    acute myeloid leukemia    myeloid leukemia
    retinitis    leukemia    multiple myeloma    myeloma


    NBAS for disorders           About GeneDecksing

    Genetic Association Database (GAD): NBAS
    Human Genome Epidemiology (HuGE) Navigator: NBAS (2 documents)

    Export disorders for NBAS gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NBAS gene, integrated from 10 sources (see all 31):
    (articles sorted by number of sources associating them with NBAS)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The neuroblastoma amplified gene, NAG: genomic structure and characterisation of the 7.3 kb transcript predominantly expressed in neuroblastoma. (PubMed id 12706883)1, 2, 3 Scott D.K.... Lunec J. (Gene 2003)
    2. Co-amplification of a novel gene, NAG, with the N-myc gene in neuroblastoma. (PubMed id 9926938)1, 2, 3 Wimmer K.... Hanash S.M. (Oncogene 1999)
    3. Genome-wide association study of conduct disorder symptomatology. (PubMed id 20585324)1, 4 Dick D.M....Bierut L. (Mol. Psychiatry 2011)
    4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    5. Neuroblastoma amplified sequence gene is associated with a novel short stature syndrome characterised by optic nerve atrophy and Pelger-Huet anomaly. (PubMed id 20577004)1, 2 Maksimova N....Onodera O. (J. Med. Genet. 2010)
    6. Relationship of DDX1 and NAG gene amplification/overexpression to the prognosis of patients with MYCN-amplified neuroblastoma. (PubMed id 17028906)1, 9 Kaneko S....Kaneko M. (J. Cancer Res. Clin. Oncol. 2007)
    7. A novel gene is disrupted at a 14q13 breakpoint of t(2;14) in a patient with mirror-image polydactyly of hands and feet. (PubMed id 11954550)1, 9 Kondoh S.... Yoshiura K. (J. Hum. Genet. 2002)
    8. DHX34 and NBAS form part of an autoregulatory NMD circuit that regulates endogenous RNA targets in human cells, zebrafish and Caenorhabditis elegans. (PubMed id 23828042)1 Longman D....CA!ceres J.F. (Nucleic Acids Res. 2013)
    9. Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method. (PubMed id 21697133)1 Oshikawa M.... Kato S. (Invest. Ophthalmol. Vis. Sci. 2011)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
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      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 51594 HGNC: 15625 AceView: NAG Ensembl:ENSG00000151779 euGenes: HUgn51594
    ECgene: NBAS H-InvDB: NBAS

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for NBAS Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NBAS gene:
    Search GeneIP for patents involving NBAS

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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