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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NAV3 Gene

protein-coding   GIFtS: 50
GCID: GC12P078250

neuron navigator 3
 Explore 14 diseases affiliated with
NAV3 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for NAV3    

Aliases
for NAV3 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Neuron Navigator 31 2     Unc53H31
POMFIL11 2 3     Pore Membrane And/Or Filament Interacting Like Protein 12
KIAA09381 3 5     Steerin 32
Pore Membrane And/Or Filament-Interacting-Like Protein 12 3     Steerin-33
Unc-53 Homolog 32 3     Steerin-33
STEERIN32 3     POMFIl15

External Ids:    HGNC: 159981   Entrez Gene: 897952   Ensembl: ENSG000000677987   OMIM: 6116295   UniProtKB: Q8IVL03   

Export aliases for NAV3 gene to outside databases

Previous GC identifers: GC12P078567 GC12P076727 GC12P075278


Summaries
for NAV3 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for NAV3:
This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded
protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety
of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance.
Multiple alternatively spliced transcript variants for this gene have been described but only one has had its
full-length nature determined. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: NAV3_HUMAN, Q8IVL0
Function: May regulate IL2 production by T-cells. May be involved in neuron regeneration




Genomic Views
for NAV3 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NC_018923.1  NT_029419.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NAV3 gene promoter:
         STAT1   Elk-1   STAT1alpha   C/EBPalpha   NF-AT   NF-AT4   NF-AT2   NF-AT3   NF-AT1   RSRFC4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: NAV3 promoter sequence
   Search SABiosciences Chromatin IP Primers for NAV3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NAV3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q14.3   Ensembl cytogenetic band:  12q21.2   HGNC cytogenetic band: 12q14.3

NAV3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NAV3 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P078250:  view genomic region     (about GC identifiers)

Start:
 78,224,685 bp from pter      End:
 78,606,790 bp from pter
Size:
 382,106 bases      Orientation:
 plus strand

Proteins
for NAV3 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: NAV3_HUMAN, Q8IVL0 (See protein sequence)
Recommended Name: Neuron navigator 3  
Size: 2385 amino acids; 255648 Da
Subcellular location: Nucleus outer membrane (By similarity)
Developmental stage: Expressed in fetal brain
Secondary accessions: Q8NFW7 Q9Y2E7
Alternative splicing: 3 isoforms:  Q8IVL0-1   Q8IVL0-2   Q8IVL0-3   

Explore the universe of human proteins at neXtProt for NAV3: NX_Q8IVL0

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8IVL0

    • NAV3 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_055718.4  
    ENSEMBL proteins: 
     ENSP00000446628   ENSP00000446132   ENSP00000381007   ENSP00000448037   ENSP00000446644  
     ENSP00000448303   ENSP00000448243   ENSP00000228327   ENSP00000266692   ENSP00000444918  

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    Uscn Proteins for NAV3

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ----
    GO:0005635nuclear envelope ----
    GO:0005640nuclear outer membrane IEA--


    NAV3 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for NAV3

    Protein Domains /
    Families
    for NAV3 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    NAV3 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR001715 CH-domain
     IPR026863 Nav3
     IPR003593 AAA+_ATPase

    Graphical View of Domain Structure for InterPro Entry Q8IVL0

    ProtoNet protein and cluster: Q8IVL0

    1 Blocks protein family: IPB001715 Calponin-like actin-binding

    UniProtKB/Swiss-Prot: NAV3_HUMAN, Q8IVL0
    Similarity: Belongs to the Nav/unc-53 family
    Similarity: Contains 1 CH (calponin-homology) domain


    Function
    for NAV3 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: NAV3_HUMAN, Q8IVL0
    Function: May regulate IL2 production by T-cells. May be involved in neuron regeneration

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NAV3
    8/98 QIAGEN miScript miRNA Assays for microRNAs that regulate NAV3 (see all 98):
    hsa-miR-548j hsa-miR-411 hsa-miR-128 hsa-miR-30d hsa-miR-3916 hsa-miR-877* hsa-miR-30a hsa-miR-3613-3p
    SwitchGear 3'UTR luciferase reporter plasmid: NAV3 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NAV3 (see all 3)
    OriGene siRNA: NAV3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NAV3

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for NAV3

    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NAV3 (see all 2)
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    Cell Line
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    Search LifeMap BioReagents cell lines for NAV3

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NAV3

    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0005524ATP binding ----
    GO:0017111nucleoside-triphosphatase activity IEA--


    NAV3 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for NAV3:
     Synthetic lethal with Ras 


    Pathways & Interactions
    for NAV3 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NAV3

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for NAV3 (Q8IVL03 ENSP000003810074) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    APCP250543, ENSP000002574304I2D: score=3 STRING: ENSP00000257430
    MDM2Q009873, ENSP000004172814I2D: score=1 STRING: ENSP00000417281
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    About this table

    Drugs & Compounds
    for NAV3 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NAV3
    Search CenterWatch for drugs/clinical trials and news about NAV3 

    Transcripts
    for NAV3 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for NAV3 gene: 
    NM_014903.4  

    Unigene Cluster for NAV3:

    Neuron navigator 3
    Hs.655301  [show with all ESTs]
    Unigene Representative Sequence: NM_014903
    17 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000549464 ENST00000536525 ENST00000397909(uc001syo.3 uc001syp.3 uc010sub.2 uc009zsf.3)
    ENST00000549369 ENST00000551277 ENST00000547725 ENST00000550503 ENST00000550673
    ENST00000552895 ENST00000550788 ENST00000548948 ENST00000552300 ENST00000551162
    ENST00000547884 ENST00000228327 ENST00000266692 ENST00000541270

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NAV3
    8/98 QIAGEN miScript miRNA Assays for microRNAs that regulate NAV3 (see all 98):
    hsa-miR-548j hsa-miR-411 hsa-miR-128 hsa-miR-30d hsa-miR-3916 hsa-miR-877* hsa-miR-30a hsa-miR-3613-3p
    SwitchGear 3'UTR luciferase reporter plasmid: NAV3 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NAV3 (see all 3)
    OriGene siRNA: NAV3
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    Clone
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    Primer
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    Additional cDNA sequence: 

    AB023155.2 AF397731.1 AJ488201.1 AK022070.1 AK294988.1 AK298525.1 AL080104.1 BC017667.2 

    8 DOTS entries:

    DT.91854748  DT.113105  DT.100644871  DT.121121108  DT.121121103  DT.121121105  DT.121121129  DT.427570 

    24/93 AceView cDNA sequences (see all 93):

    BU735926 AI929563 Z42103 NM_014903 Z44883 AU120878 AA374301 Z38462 
    F10608 AI539348 AA082052 BM684673 F13011 AA716602 AB023155 AJ488201 
    AI929520 BM713910 AA910041 AF397731 BM714931 AI814858 M85495 R42053 

    GeneLoc Exon Structure


    Expression
    for NAV3 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NAV3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    NAV3 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 3 LifeMap Cells 
    NameCategory
    Line H7 (WA07) (Embryonic Stem Cell)Early Embryo, Inner Cell Mass
    Line H9 (WA09) (Embryonic Stem Cell)Early Embryo, Inner Cell Mass
    Adult human kidney epithelial cells (Primary Cell)Kidney
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See NAV3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NAV3

    SOURCE GeneReport for Unigene cluster: Hs.655301

    UniProtKB/Swiss-Prot: NAV3_HUMAN, Q8IVL0
    Tissue specificity: Highly expressed in brain. Expressed at low levels in heart and placenta. Present in activated
    T-cells but not in resting T-cells (at protein level). Down-regulated in primary neuroblastoma

        SABiosciences Custom PCR Arrays for NAV3
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NAV3

    Orthologs
    for NAV3 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for NAV3 gene from 6/19 species (see all 19)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Nav31 , 5 neuron navigator 31, 5 87.67(n)1
    94.03(a)1    		   10 (57.18 cM)5
    2603151  NM_001081035.11  NP_001074504.11 
     1096826605 
    chicken
    (Gallus gallus)    		 Aves NAV31 neuron navigator 3 81.35(n)
    88.21(a)    		   417869  NM_001159347.1  NP_001152819.1 
    lizard
    (Anolis carolinensis)    		 Reptilia NAV36
    		 --
    		 86(a)
    		 1 ↔ 1
    		 5(41520446-41739785)
    zebrafish
    (Danio rerio)    		 Actinopterygii nav31 neuron navigator 3 66.41(n)
    68.65(a)    		   567779  NM_001045143.2  NP_001038608.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta sick6
    		 sickie
    		 22(a)
    		 1 → many
    		 2L(19796365-19958424)
    worm
    (Caenorhabditis elegans)    		 Secernentea unc-536
    		 Adapter protein unc-53
    		 24(a)
    		 1 → many
    		 II(11058043-11089398)


    ENSEMBL Gene Tree for NAV3 (if available)
    TreeFam Gene Tree for NAV3 (if available) 

    Paralogs
    for NAV3 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NAV3 gene
    NAV12  NAV22  
    4 SIMAP similar genes for NAV3 using alignment to 11 protein entries:     NAV3_HUMAN (see all proteins):
    NAV2    ACTN1    NAV1    DKFZp434O2321

    NAV3 for paralogs           About GeneDecksing



    Genomic Variants
    for NAV3 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/6954 NCBI SNPs in NAV3 are shown (see all 6954)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 12 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1438390531,2
    		--78223104(+) TTCCTG/TGAGTG 1 -- us2k10--------
    rs1875538761,2
    		--78223149(+) TTGCTA/GGCAAT 1 -- us2k10--------
    rs1384134521,2
    		--78223176(+) ATATGC/TTTTGA 1 -- us2k10--------
    rs1932835381,2
    		--78223200(+) AATCAA/GTTTTT 1 -- us2k10--------
    rs15690281,2
    		C,F,O,A,--78223287(+) CTAAAC/ACTCAT 1 -- us2k110Minor allele frequency- A:0.26EA NA WA 580
    rs122312961,2
    		C,F,H,--78223346(+) AAGTTA/GTAATG 1 -- us2k111Minor allele frequency- N:0.01NS EA NA CSA 760
    rs1429889891,2
    		--78223422(+) ACCACC/TAGTGT 1 -- us2k10--------
    rs1176968321,2
    		F,--78223452(+) CCCGCT/GGTGTA 1 -- us2k11Minor allele frequency- G:0.02EA 120
    rs1855097171,2
    		--78223465(+) GCCCAC/TTTGGG 1 -- us2k10--------
    rs170443121,2
    		C,F,H,--78223572(+) CTATAA/CATTAC 1 -- us2k18Minor allele frequency- C:0.04NA NS EA WA 680

    HapMap Linkage Disequilibrium report for NAV3 (78224685 - 78474685 bp, first 250kb of NAV3)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 7 variations for NAV3
         2 CNVs: 101566 53152
         5 Indels: 45081 101567 60100 39912 41596

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    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NAV3
    DNA2.0 Custom Variant and Variant Library Synthesis for NAV3

    Disorders / Diseases
    for NAV3 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    NAV3 for disorders           About GeneDecksing

    OMIM gene information: 611629    OMIM disorders: --

    UniProtKB/Swiss-Prot: NAV3_HUMAN, Q8IVL0
  • Note=A chromosomal aberration disrupting NAV3 has been found in patients with Sezary syndrome. Translocation
    • t(12;18)(q21;q21.2)

    14 diseases for NAV3:    About MalaCards
    subcutaneous panniculitis-like t-cell lymphoma    neuronitis    panniculitis    adult t-cell leukemia
    fanconi's anemia    leukemia/lymphoma    cutaneous t cell lymphoma    familial colorectal cancer
    t-cell leukemia    colorectal cancer    anemia    leukemia
    influenza    neuroblastoma

    2 diseases from the University of Copenhagen DISEASES database for NAV3:
    Cutaneous T cell lymphoma     Influenza
    Human Genome Epidemiology (HuGE) Navigator: NAV3 (6 documents)

    Export disorders for NAV3 gene to outside databases

    Publications
    for NAV3 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NAV3 gene, integrated from 9 sources (see all 22):
    (articles sorted by number of sources associating them with NAV3)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Neuron navigator: a human gene family with homology to unc-53, a cell guidance gene from Caenorhabditis elegans. (PubMed id 12079279)1, 2, 3 Maes T.... Buesa C. (2002)
    2. Pore membrane and/or filament interacting like protein 1 (POMFIL1) is predominantly expressed in the nervous system and encodes different protein isoforms. (PubMed id 12062803)1, 2, 3 Coy J.F....Poustka A. (2002)
    3. Sensory deficits in mice hypomorphic for a mammalian homologue of unc-53. (PubMed id 15158073)1, 2 Peeters P.J.... Moechars D.W.E. (2004)
    4. Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10231032)1, 2 Nagase T.... Ohara O. (1999)
    5. Primary cutaneous T-cell lymphomas show a deletion or translocation affecting NAV3, the human UNC-53 homologue. (PubMed id 16166283)2, 9 Karenko L.... Ranki A. (2005)
    6. Potential role of a navigator gene NAV3 in colorectal cancer. (PubMed id 22173670)1 Carlsson E....Krohn K. (2012)
    7. NAV3 copy number changes and target genes in basal and squamous cell cancers. (PubMed id 21995814)1 Maliniemi P....Ranki A. (2011)
    8. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    9. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    10. Cutaneous-type adult T-cell leukemia/lymphoma does no t primarily show deletion of NAV3 gene. (PubMed id 19626031)1 Kawai K....Kanekura T. (2010)

    External Searches for NAV3 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing NAV3 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 89795 HGNC: 15998 AceView: NAV3 Ensembl:ENSG00000067798 euGenes: HUgn89795
    ECgene: NAV3 H-InvDB: NAV3

    Other Databases showing NAV3 gene

    (According to HUGE)
    About This Section
    HUGE: KIAA0938

    Specialized Databases showing NAV3 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NAV3 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for NAV3 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for NAV3 gene:
    Search GeneIP for patents involving NAV3

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