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NAV1 Gene

protein-coding GIFtS: 54

GC01P199859

neuron navigator 1
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
DKFZp781D0314 ^¹, ²
FLJ12560 ^¹, ²
FLJ14203 ^¹, ²
KIAA1151 ^¹, ², ³, ⁵
KIAA1213 ^³
MGC14961 ^¹, ²
POMFIL3 ^¹, ², ³, ⁵
STEERIN1 ^³
Steerin-1 ^³
steerin-1 ^¹, ²
unc53H1 ^³

Descriptions
Pore membrane and/or filament-interacting-like protein 3 ^³
Unc-53 homolog 1 ^³
neuron navigator 1 ^²
neuron navigator-1 ^²
pore membrane and/or filament interacting like protein 3 ^²

External Ids
HGNC: 15989¹
Entrez Gene: 89796²
UniProtKB: Q8NEY1³
Ensembl: ENSG00000134369⁷

Search outside databases for aliases for NAV1 gene

Previous GC identifers: GC01P199392 GC01P197115 GC01P198083 GC01P198905 GC01P198349

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for NAV1:

This gene belongs to the neuron navigator family and is expressed predominantly in the nervous

system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic

for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a

Caenorhabditis elegans gene involved in axon guidance. The exact function of this gene is not

known. [provided by RefSeq]

UniProtKB/Swiss-Prot: NAV1_HUMAN, Q8NEY1

Function: May be involved in neuronal migration (By similarity)

Gene Wiki entry for NAV1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the NAV1 gene

Entrez Gene cytogenetic band: 1q32.3 Ensembl cytogenetic band: 1q32.1 HGNC cytogenetic band: 1q32.3

NAV1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01P199859: (about GC identifiers)

Start:	199,859,224 bp from pter
End:	200,062,720 bp from pter
Size:	203,497 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000001.9 NT_004487.18

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: NAV1_HUMAN, Q8NEY1 (See protein sequence)

Recommended Name: Neuron navigator 1

Size: 1877 amino acids; 202472 Da

Subunit: Interacts with tubulin (By similarity)

Subcellular location: Cytoplasm, cytoskeleton (By similarity). Note=Associates with a subset of

microtubule plus ends. Enriched in neuronal growth cones (By similarity)

Developmental stage: Expressed in fetal brain and heart

Sequence caution: Sequence=CAH71925.1; Type=Erroneous gene model prediction; Sequence=CAI17010.1;

Type=Erroneous gene model prediction;

Secondary accessions: Q5SVH1 Q5SVH2 Q5SVH3 Q5SVH7 Q5VUY9 Q8IVL2 Q96II1 Q9H7V9 Q9H9S9 Q9H9T5 Q9UGI1

Q9ULK7 Q9ULR9

Alternative splicing: 7 isoforms: Q8NEY1-1 Q8NEY1-2 Q8NEY1-3 Q8NEY1-4 Q8NEY1-5 Q8NEY1-6 Q8NEY1-7

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_065176.2

ENSEMBL proteins:

ENSP00000356271 ENSP00000356269 ENSP00000356265 ENSP00000295624 ENSP00000356264 ENSP00000356266

ENSP00000375828 ENSP00000356270

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Neuron navigator 1)
	Human Recombinant Proteins from Abnova (NAV1)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IEA	--
GO:0005856	cytoskeleton	IEA	--
GO:0005874	microtubule	IEA	--

About this table

Antibodies for NAV1:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for NAV1
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (Neuron navigator 1), each with their Abpromise^SM
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Search Novus for antibodies for NAV1

Assays for NAV1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q8NEY1

ProtoNet protein and cluster: Q8NEY1

1 Blocks protein family: IPB008162 Inorganic pyrophosphatase

UniProtKB/Swiss-Prot: NAV1_HUMAN, Q8NEY1

Similarity: Belongs to the Nav/unc-53 family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (NAV1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (NAV1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_020443

Applied Biosystems Silencer® siRNAs for NAV1

Sigma-Aldrich siRNA for NAV1

Sigma-Aldrich shRNA for NAV1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for NAV1
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_020443
Myc/DDK tagged cDNA clone in CMV expression vector: NM_020443
untagged cDNA clones in CMV expression vector (see all 2): AK056158

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_020443

UniProtKB/Swiss-Prot: NAV1_HUMAN, Q8NEY1

Function: May be involved in neuronal migration (By similarity)

2 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000166	nucleotide binding	IEA	--
GO:0017111	nucleoside-triphosphatase activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

5/7 Interacting proteins for NAV1 (ENSP00000356270³) via UniProtKB, MINT, and/or STRING (see all 7 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
SCN1A	ENSP00000303540³	STRING (score=.889)
SCN8A	ENSP00000346534³	STRING (score=.874)
KRIT1	ENSP00000344668³	STRING (score=.866)
SCN2A	ENSP00000364586³	STRING (score=.781)
SCN4A	ENSP00000006839³	STRING (score=.744)

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3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007275	multicellular organismal development	IEA	--
GO:0007399	nervous system development	IEA	--
GO:0030154	cell differentiation	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for NAV1

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (NAV1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (NAV1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_020443

Sigma-Aldrich siRNA for NAV1

Sigma-Aldrich shRNA for NAV1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_020443

REFSEQ mRNAs for NAV1 gene:

NM_020443.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_020443

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_020443
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_020443
                                 untagged cDNA clones in CMV expression vector (see all 2): AK056158

Additional cDNA sequence:

AB032977.3 AB033039.1 AF086348.1 AJ488101.1 AK022622.1 AK022631.1 AK024265.1 AK056158.1

AK091567.1 AL133664.1 AY043013.1 BC007523.1 BC069250.1 BC117683.1 BX648460.1 CR936811.1

21 DOTS entries:

DT.95311045 DT.95143036 DT.100017088 DT.205340 DT.101983412 DT.121338801 DT.95343066 DT.95131868

DT.100794609 DT.91826624 DT.95086544 DT.87046235 DT.91710046 DT.121338860 DT.75169939 DT.91954325

DT.86841911 DT.95311047 DT.40112361 DT.75110211 DT.97824207

24/293 AceView cDNA sequences (see all 293 ):

T16632 F03942 BM549511 BG118553 AI379115 BP344765 Z44991 AA564854

BQ185652 BM558821 AI272296 AK091567 AA043878 BU742933 BM052858 BU742921

BE326555 BC069250 AI937060 AA233277 Z41591 CB159133 AK056158 BU731888

highest scoring ESTs for NAV1:

AA128296 AI003520 AI858038 Z78399 AA011315 AA043878 AA043997 AA128315 AA232974 AA233277

Unigene Cluster for NAV1:

Neuron navigator 1

Hs.585374 [show with all ESTs]

Unigene Representative Sequence: NM_020443

GeneLoc Exon Structure

5/7 Alternative Splicing Database (ASD) splice patterns (SP) for NAV1 (see all 7 )

ExUns:	1	^	2a	·	2b	^	3	^	4	^	5	^	6a	·	6b	^	7a	·	7b	^	8	^	9	^	10	^	11	^	12	^	13	^	14	^	15	^	16	^	17a	·	17b	^	18	^	19	^	20a	·	20b	^	21	^
SP1:																																																	-
SP2:
SP3:									-
SP4:
SP5:							-		-

ExUns:	22	^	23
SP1:
SP2:
SP3:
SP4:
SP5:

About this scheme

ECgene alternative splicing isoforms for NAV1

8 Ensembl transcripts including schematic representations:

ENST00000367302 ENST00000367300 ENST00000367296 ENST00000295624 ENST00000367295 ENST00000367297

ENST00000391966 ENST00000367301

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

NAV1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for NAV1

¹ / ² / ³

19 probe-sets matching NAV1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
53975_at²^{, 3}	U95-B	1	1.00	1.00	0.93	1.20	Z78399	1.00	1.00	1.00	1
52850_at²^{, 3}	U95-B	1	1.00	1.00	0.91	1.06	AA128296	1.00	1.00	1.00	1
47419_at²^{, 3}	U95-B	1	1.00	1.00	0.92	1.13	AI858038	1.00	1.00	1.00	1
86612_at²^{, 3}	U95-E	1	1.00	1.00	-0.12	0.58	AI937060	0.80	1.00	0.91	1
58305_at²^{, 3}	U95-B	1	1.00	1.00	0.71	1.07	AI003520	1.00	1.00	1.00	1
224773_at²^{, 3}	U133-B	1	1.00	1.00	--	--	N57538	0.80	1.00	0.91	1
227584_at²^{, 3}	U133-B	1	1.00	1.00	--	--	BF339566	0.80	1.00	0.91	1
224770_s_at²^{, 3}	U133-B	1	1.00	1.00	--	--	AI937060	0.80	1.00	0.91	1
224772_at²^{, 3}	U133-B	1	1.00	1.00	--	--	AB032977	0.60	0.78	0.69	1
224771_at²^{, 3}	U133-B	1	1.00	1.00	--	--	AI937060	0.80	1.00	0.91	1
233870_at²^{, 3}	U133-B	2	1.00	0.95	--	--	AB033039	0.60	1.00	0.82	1
224774_s_at²^{, 3}	U133-B	2	1.00	0.73	--	--	AK022622	0.80	1.00	0.91	1
224773_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
227584_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
224770_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
224772_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
224771_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
233870_at²	U133Plus2	2	1.00	0.95	--	--	--	--	--	--	--
224774_s_at²	U133Plus2	2	1.00	0.73	--	--	--	--	--	--	--

GeneDecks NAV1 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TCTCCTCCCA

SOURCE GeneReport for Unigene cluster: Hs.585374
UniProtKB/Swiss-Prot: NAV1_HUMAN, Q8NEY1
Tissue specificity: Broadly expressed at low levels. Expressed at high levels in heart, skeletal
muscle and placenta

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for NAV1 gene from 3 species

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	NAV1¹	--	neuron navigator 1	90.83(n) 96.53(a)	490238 XM_843488.1 XP_848581.1
mouse (Mus musculus)	Nav1^{1, 5}	1⁵	neuron navigator 1^{1, 5}	90.12(n)¹ 96.36(a)¹	215690¹ NM_173437.1¹ NP_775613.1¹ AA399795⁵ AA968123⁵ (see all 24)
zebrafish (Danio rerio)	LOC100005000¹	--	similar to neuron navigator 1	62.56(n) 62.46(a)	100005000 XM_001920952.1 XP_001920987.1

About this table Species with no ortholog for NAV1

ENSEMBL Gene Tree for NAV1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for NAV1 gene

NAV3² NAV2²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/1014 NCBI SNPs in NAV1 are shown (see all 1014 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 309)

AB	SNP ID	Valid	Chr 1 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs1022361^1,2	A,C,F,H,O	200056893(-)	`AAAGCT/CCGGAG`	1	--	ut3¹		17	MN EU EA WA NA	1654
	rs2820289^1,2	A,C,F,H,O	200043873(+)	`CACCTC/TGTCCT`	1	S/L	mis¹ ese³		12	EU EA WA NA	1054
	rs1032524^1,2	A,C,F,H,O	200057449(-)	`ATTGTA/GCATCT`	1	--	ut3¹ ese³		13	MN EU EA WA NA	2658
	rs2644128^1,2	A,C,F,H	200060063(-)	`AGCCAG/CAACTT`	1	--	ut3¹		8	EU EA WA	838
	rs10464^1,2	A,C,F,H	200058929(+)	`TGAATC/TCAATA`	1	--	ut3¹ ese³		10	MN EA NA EU WA	1000
--	rs2644129^1,2	A,C,F,H	200059123(-)	`acacaC/Tacaca`	1	--	ut3¹ ese³		4	EU EA WA	406
--	rs7364578^1,2	A,C,F,H	199883250(+)	`AGAGGG/AGTTCA`	1	--	ng5¹		4	EU EA WA	412
	rs659470^1,2	A,C,F,H	199882142(+)	`ATGTCT/CGTCTA`	1	--	ng5¹		5	MN EU EA WA	596
	rs1736450^1,2	A,C,F,H	199883458(+)	`TAGGGT/CGGGAC`	1	--	ng5¹		9	MN EU EA WA	1020
	rs16849342^1,2	C,F,H	200021067(+)	`AATCAG/CCGGGA`	1	H/Q	mis¹ ese³		12	NA EU EA WA	1050

About this table

HapMap Linkage Disequilibrium images for NAV1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 611628

1 PharmGKB disease relationship for NAV1 gene

Disease	PharmGKB Relations	PubMed IDs for articles supporting these relationships
Leukemia, Lymphocytic, Acute, L1	FA GN	12730115

About this table

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/14 PubMed articles for NAV1 gene (see all 14 ):

Neuron navigator: a human gene family with homology to unc-53, a cell guidance gene from Caenorhabditis elegans. (PubMed id 12079279)^{2, 3, 4} Maes T.... Buesa C. (2002)
Pore membrane and/or filament interacting like protein 1 (POMFIL1) is predominantly expressed in the nervous system and encodes different protein isoforms. (PubMed id 12062803)^{2, 3, 4} Coy J.F....Poustka A. (2002)
Sensory deficits in mice hypomorphic for a mammalian homologue of unc-53. (PubMed id 15158073)^{3, 4} Peeters P.J.... Moechars D.W.E. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{3, 4} Ota T....Sugano S. (2004)
Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. (PubMed id 10574461)^{3, 4} Hirosawa M....Ohara O. (1999)
A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)⁴ Dephoure N.... Gygi S.P. (2008)
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)³ Kimura K.... Sugano S. (2006)
The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)⁴ Gregory S.G.... Bentley D.R. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)⁴ Gerhard D.S....Malek J. (2004)
Classification of pediatric acute lymphoblastic leukemia by gene expression profiling. (PubMed id 12730115)⁷ Ross M.E....Downing J.R. (2003)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 89796	HGNC: 15989	AceView: NAV1	Ensembl:ENSG00000134369	euGenes: HUgn89796
ECgene: NAV1	H-InvDB: NAV1

(According to HUGE)
About This Section

HUGE: KIAA1151 KIAA1213

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for NAV1
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for NAV1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for NAV1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for NAV1		Antibodies for NAV1
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for NAV1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (NAV1)
	Search for Antibodies
	Chimera RNAi (NAV1)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

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	Recombinant Proteins (Neuron navigator 1)
	Antibodies (Neuron navigator 1)

Search OriGene for NAV1

Search Tocris compounds for NAV1

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Search Novus for antibodies for NAV1

GeneCards Homepage - Last full update: 1 Jul 2009 Incremental update: 13 Oct 2009

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NAV1 Gene

protein-coding GIFtS: 54

Aliases &
Descriptions
for NAV1

Summaries
for NAV1

Genomic Location
for NAV1

Proteins
for NAV1

Protein Domains/
Families
for NAV1

Gene Function
for NAV1

Pathways & Interactions
for NAV1

Drugs & Compounds
for NAV1

Transcripts
for NAV1

Expression
for NAV1

Orthologs
for NAV1

Paralogs
for NAV1

SNPs/Variants
for NAV1

Disorders & Mutations
for NAV1

Medical News
for NAV1

Publications
for NAV1

Search for NAV1

Genome Databases showing NAV1

Other Databases showing NAV1

Specialized Databases showing NAV1

Licensable Technologies
for NAV1

Services
for NAV1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

NAV1 Gene

protein-coding GIFtS: 54

Aliases & Descriptionsfor NAV1

Summariesfor NAV1

Genomic Locationfor NAV1

Proteinsfor NAV1

Protein Domains/Familiesfor NAV1

Gene Functionfor NAV1

Pathways & Interactionsfor NAV1

Drugs & Compoundsfor NAV1

Transcriptsfor NAV1

Expression for NAV1

Orthologsfor NAV1

Paralogsfor NAV1

SNPs/Variantsfor NAV1

Disorders & Mutationsfor NAV1

Medical Newsfor NAV1

Publicationsfor NAV1

Search for NAV1

Genome Databases showing NAV1

Other Databases showing NAV1

Specialized Databases showing NAV1

Licensable Technologiesfor NAV1

Servicesfor NAV1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for NAV1

Summaries
for NAV1

Genomic Location
for NAV1

Proteins
for NAV1

Protein Domains/
Families
for NAV1

Gene Function
for NAV1

Pathways & Interactions
for NAV1

Drugs & Compounds
for NAV1

Transcripts
for NAV1

Expression
for NAV1

Orthologs
for NAV1

Paralogs
for NAV1

SNPs/Variants
for NAV1

Disorders & Mutations
for NAV1

Medical News
for NAV1

Publications
for NAV1

Licensable Technologies
for NAV1

Services
for NAV1