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Aliases for NATD1 Gene

Aliases for NATD1 Gene

  • N-Acetyltransferase Domain Containing 1 2 3 5
  • N-Acetyltransferase Domain-Containing Protein 1 3 4
  • Transcript Expressed During Hematopoiesis 2 2 3
  • Gene Trap Locus F3b 2 3
  • C17orf103 3 4
  • Gtlf3b 3 4
  • Chromosome 17 Open Reading Frame 103 2
  • Protein GTLF3B 3
  • Protein NATD1 3

External Ids for NATD1 Gene

Previous HGNC Symbols for NATD1 Gene

  • C17orf103

Summaries for NATD1 Gene

GeneCards Summary for NATD1 Gene

NATD1 (N-Acetyltransferase Domain Containing 1) is a Protein Coding gene.

Additional gene information for NATD1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NATD1 Gene

Genomics for NATD1 Gene

Regulatory Elements for NATD1 Gene

Enhancers for NATD1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17H021252 1.2 ENCODE dbSUPER 10.2 -0.2 -153 1.4 TBP ARID4B SIN3A FEZF1 GLIS2 THAP11 NFYC USF2 REST SNIP1 ENSG00000235530 TMEM11 NATD1 EIF1P5
GH17H021274 1.9 FANTOM5 Ensembl ENCODE dbSUPER 5.7 -22.5 -22461 1.9 FOXA2 ARID4B SIN3A DMAP1 FOS SP3 SP5 MXD4 NFYC REST ENSG00000235530 KCNJ12 NATD1 MAP2K3 CCDC144NL PIR52124
GH17H021275 1.2 FANTOM5 dbSUPER 8.1 -19.7 -19745 0.3 HDAC1 PKNOX1 ATF1 ARNT KLF17 CHAMP1 TCF12 GATA2 EGR1 ATF7 NATD1 PIR52124 MAP2K3
GH17H021208 1.6 Ensembl ENCODE dbSUPER 5.2 +40.7 40673 7.6 PKNOX1 MLX ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF766 ZNF207 ZNF143 DHRS7B TMEM11 ENSG00000235530 FAM106B NATD1 GC17M021160
GH17H021281 1.8 FANTOM5 ENCODE dbSUPER 4.5 -32.8 -32751 9.2 HDGF PKNOX1 FOXA2 MLX ARID4B SIN3A DMAP1 YY1 ZNF143 ZNF548 MAP2K3 KCNJ12 DHRS7B NATD1 GC17P023984
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around NATD1 on UCSC Golden Path with GeneCards custom track

Promoters for NATD1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Locations for NATD1 Gene

Genomic Locations for NATD1 Gene
14,541 bases
Minus strand

Genomic View for NATD1 Gene

Genes around NATD1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NATD1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NATD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NATD1 Gene

Proteins for NATD1 Gene

  • Protein details for NATD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein NATD1
    Protein Accession:
    Secondary Accessions:
    • A8MWQ7
    • B3KX70

    Protein attributes for NATD1 Gene

    113 amino acids
    Molecular mass:
    13032 Da
    Quaternary structure:
    No Data Available

neXtProt entry for NATD1 Gene

Post-translational modifications for NATD1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for NATD1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for NATD1 Gene

Domains & Families for NATD1 Gene

Gene Families for NATD1 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for NATD1 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the NATD1 family.
  • Belongs to the NATD1 family.
genes like me logo Genes that share domains with NATD1: view

No data available for Suggested Antigen Peptide Sequences for NATD1 Gene

Function for NATD1 Gene

Phenotypes From GWAS Catalog for NATD1 Gene

Gene Ontology (GO) - Molecular Function for NATD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with NATD1: view
genes like me logo Genes that share phenotypes with NATD1: view

Animal Models for NATD1 Gene

MGI Knock Outs for NATD1:

Animal Model Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for NATD1 Gene

Localization for NATD1 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for NATD1 gene
Compartment Confidence
extracellular 2
cytosol 2
mitochondrion 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for NATD1 Gene

Pathways & Interactions for NATD1 Gene

SuperPathways for NATD1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for NATD1 Gene


No data available for Pathways by source and SIGNOR curated interactions for NATD1 Gene

Drugs & Compounds for NATD1 Gene

No Compound Related Data Available

Transcripts for NATD1 Gene

mRNA/cDNA for NATD1 Gene

(1) REFSEQ mRNAs :
(288) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for NATD1 Gene

No ASD Table

Relevant External Links for NATD1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for NATD1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for NATD1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for NATD1 Gene

This gene is overexpressed in Bone (60.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for NATD1 Gene

Protein tissue co-expression partners for NATD1 Gene

NURSA nuclear receptor signaling pathways regulating expression of NATD1 Gene:

genes like me logo Genes that share expression patterns with NATD1: view

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for NATD1 Gene

Orthologs for NATD1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for NATD1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C17H17orf103 33
  • 98.82 (n)
(Rattus norvegicus)
Mammalia Gtlf3b 33
  • 91.21 (n)
(Mus musculus)
Mammalia Gm16515 33
  • 90.91 (n)
Natd1 16
(Bos Taurus)
Mammalia C19H17orf103 33
  • 90.86 (n)
(Gallus gallus)
Aves C14H17ORF103 33
  • 84.24 (n)
tropical clawed frog
(Silurana tropicalis)
Amphibia c17orf103 33
  • 72.17 (n)
Str.20480 33
African clawed frog
(Xenopus laevis)
Amphibia Xl.3877 33
(Danio rerio)
Actinopterygii zgc:110779 33
  • 71.65 (n)
Species where no ortholog for NATD1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for NATD1 Gene

Gene Tree for NATD1 (if available)
Gene Tree for NATD1 (if available)

Paralogs for NATD1 Gene

No data available for Paralogs for NATD1 Gene

Variants for NATD1 Gene

Sequence variations from dbSNP and Humsavar for NATD1 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs1000032782 -- 21,251,766(+) CCACC(G/T)TTCAG intron-variant
rs1000129931 -- 21,246,222(+) TATAA(A/G)TAATA intron-variant
rs1000191915 -- 21,254,533(+) CGGAG(-/TCTC)TCTCT upstream-variant-2KB
rs1000250086 -- 21,238,596(+) ATCTG(A/C)CTGGA downstream-variant-500B
rs1000270880 -- 21,241,122(+) TGCTA(C/G)AACAC utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for NATD1 Gene

Variant ID Type Subtype PubMed ID
nsv1059146 CNV gain 25217958
nsv1078306 OTHER inversion 25765185
nsv953852 CNV deletion 24416366

Variation tolerance for NATD1 Gene

Gene Damage Index Score: 3.01; 49.97% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for NATD1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NATD1 Gene

Disorders for NATD1 Gene

Relevant External Links for NATD1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for NATD1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NATD1 Gene

Publications for NATD1 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 60
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 60
  3. Next-generation sequencing to generate interactome datasets. (PMID: 21516116) Yu H … Vidal M (Nature methods 2011) 3 60
  4. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody MC … Nusbaum C (Nature 2006) 4 60
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 4 60

Products for NATD1 Gene

Sources for NATD1 Gene

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