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Aliases for NAT9 Gene

Aliases for NAT9 Gene

  • N-Acetyltransferase 9 (GCN5-Related, Putative) 2 3
  • Embryo Brain-Specific Protein 4
  • N-Acetyltransferase 9 2
  • EC 2.3.1.- 4
  • EBS 4

External Ids for NAT9 Gene

Previous GeneCards Identifiers for NAT9 Gene

  • GC17M070279
  • GC17M072766
  • GC17M068177

Summaries for NAT9 Gene

GeneCards Summary for NAT9 Gene

NAT9 (N-Acetyltransferase 9 (GCN5-Related, Putative)) is a Protein Coding gene. Diseases associated with NAT9 include conjunctival folliculosis and ophthalmia neonatorum. Among its related pathways are Biological oxidations. GO annotations related to this gene include transferase activity, transferring acyl groups other than amino-acyl groups and N-acetyltransferase activity.

Gene Wiki entry for NAT9 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NAT9 Gene

Genomics for NAT9 Gene

Regulatory Elements for NAT9 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for NAT9 Gene

Chromosome:
17
Start:
74,770,547 bp from pter
End:
74,776,395 bp from pter
Size:
5,849 bases
Orientation:
Minus strand

Genomic View for NAT9 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for NAT9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NAT9 Gene

Proteins for NAT9 Gene

  • Protein details for NAT9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BTE0-NAT9_HUMAN
    Recommended name:
    N-acetyltransferase 9
    Protein Accession:
    Q9BTE0
    Secondary Accessions:
    • B2R7F0
    • Q9BTD0
    • Q9Y3T3

    Protein attributes for NAT9 Gene

    Size:
    207 amino acids
    Molecular mass:
    23361 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for NAT9 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for NAT9 Gene

Proteomics data for NAT9 Gene at MOPED

Post-translational modifications for NAT9 Gene

  • Ubiquitination at Lys 118
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for NAT9 Gene

Domains & Families for NAT9 Gene

Gene Families for NAT9 Gene

Protein Domains for NAT9 Gene

Suggested Antigen Peptide Sequences for NAT9 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9BTE0

UniProtKB/Swiss-Prot:

NAT9_HUMAN :
  • Contains 1 N-acetyltransferase domain.
  • Belongs to the acetyltransferase family. GNAT subfamily.
Domain:
  • Contains 1 N-acetyltransferase domain.
Family:
  • Belongs to the acetyltransferase family. GNAT subfamily.
genes like me logo Genes that share domains with NAT9: view

Function for NAT9 Gene

Enzyme Numbers (IUBMB) for NAT9 Gene

Gene Ontology (GO) - Molecular Function for NAT9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 21516116
GO:0008080 N-acetyltransferase activity IBA --
genes like me logo Genes that share ontologies with NAT9: view

Phenotypes for NAT9 Gene

genes like me logo Genes that share phenotypes with NAT9: view

Animal Model Products

No data available for Molecular function , Animal Models , Transcription Factor Targets and HOMER Transcription for NAT9 Gene

Localization for NAT9 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for NAT9 Gene COMPARTMENTS Subcellular localization image for NAT9 gene
Compartment Confidence
cytoskeleton 2
extracellular 2
nucleus 2
plasma membrane 2
cytosol 1
endoplasmic reticulum 1
lysosome 1
mitochondrion 1
vacuole 1

Gene Ontology (GO) - Cellular Components for NAT9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0043234 protein complex IDA --
genes like me logo Genes that share ontologies with NAT9: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for NAT9 Gene

Pathways & Interactions for NAT9 Gene

SuperPathways for NAT9 Gene

Superpath Contained pathways
1 Biological oxidations
genes like me logo Genes that share pathways with NAT9: view

Pathways by source for NAT9 Gene

1 BioSystems pathway for NAT9 Gene

Gene Ontology (GO) - Biological Process for NAT9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006474 N-terminal protein amino acid acetylation IBA --
GO:0008152 metabolic process --
genes like me logo Genes that share ontologies with NAT9: view

No data available for SIGNOR curated interactions for NAT9 Gene

Drugs & Compounds for NAT9 Gene

No Compound Related Data Available

Transcripts for NAT9 Gene

Unigene Clusters for NAT9 Gene

N-acetyltransferase 9 (GCN5-related, putative):
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for NAT9

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for NAT9 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b · 3c · 3d ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c · 6d ^ 7a · 7b · 7c · 7d · 7e ^ 8 ^ 9 ^ 10a · 10b · 10c ^
SP1: - - - - - - - - - - - - - - - - - -
SP2: - - - - - - - - - - - - - - - - - -
SP3: - - - - - - - - - - - - - - - - - -
SP4: - - - - - - - - - - - - - - - - - -
SP5: - - - - - - - - - - - - - - - - - -
SP6: - - - - - - - - - - - - - -
SP7: - - - - - - - - - - - - - - -
SP8: - - - - - - - - - - - - - - - - - -
SP9: - - - - - - - - - - - - - - - - - -
SP10: - - - - - - - - - - - - - - -
SP11: - - - - - - - - - - - - - -
SP12: - - - - - - - - - - - - - - - - -
SP13: - - - - - - - - - - - - - - - - -
SP14: - - - - - - - - - - - - - - - - -
SP15: - - - - - - - - - - - - - - - - - -
SP16: - - - - - - - - - - - - - - - - - -
SP17: - - - - - - - - - - - - - - -
SP18: - - - - - - - - - - - - - - - - - -
SP19: - - - - - - - - - - - - - - - - -
SP20: - - - - - - - - - - - - - - -
SP21: - - - - - - - - - - - - -
SP22: - - - - - - - - - - - - - - - - - -
SP23: - - - - - - - - -
SP24: - - - - - - - -
SP25: - - - - - - - - - - - - - - - -
SP26: - - - - - - - - - -
SP27: - - - - - - - - - -
SP28: - - - - - -
SP29: - - - - - - - - - - - - - - - -
SP30: - - - - - - - - - - - - - - - -
SP31: - - - - - - - - -
SP32: - - - - - - - - - - - - - - - - - - -
SP33: - - - - - - - - -
SP34: - - - - - - -
SP35: - - - - - - -
SP36: - - -
SP37: - -
SP38:

ExUns: 11a · 11b · 11c · 11d · 11e ^ 12a · 12b · 12c · 12d · 12e · 12f · 12g ^ 13a · 13b · 13c · 13d · 13e · 13f · 13g · 13h · 13i · 13j · 13k · 13l
SP1: - - - -
SP2: - - - -
SP3: - - - - -
SP4: - - - -
SP5: - - - - - - - - - -
SP6:
SP7: -
SP8: - - -
SP9: - - - - - - - - - -
SP10: -
SP11:
SP12: - - -
SP13: - - - - - - - - - -
SP14: - - -
SP15: -
SP16: - - -
SP17:
SP18:
SP19:
SP20:
SP21:
SP22:
SP23:
SP24:
SP25: - - - - - -
SP26:
SP27:
SP28:
SP29:
SP30:
SP31:
SP32:
SP33:
SP34:
SP35:
SP36:
SP37:
SP38: -

Relevant External Links for NAT9 Gene

GeneLoc Exon Structure for
NAT9
ECgene alternative splicing isoforms for
NAT9

Expression for NAT9 Gene

mRNA expression in normal human tissues for NAT9 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for NAT9 Gene



SOURCE GeneReport for Unigene cluster for NAT9 Gene Hs.144058

genes like me logo Genes that share expression patterns with NAT9: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for NAT9 Gene

Orthologs for NAT9 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for NAT9 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia NAT9 35
  • 92.49 (n)
  • 90.99 (a)
NAT9 36
  • 87 (a)
OneToOne
dog
(Canis familiaris)
Mammalia NAT9 35
  • 87.42 (n)
  • 88.24 (a)
NAT9 36
  • 87 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Nat9 35
  • 85.2 (n)
  • 82.44 (a)
Nat9 16
Nat9 36
  • 70 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia NAT9 35
  • 99.68 (n)
  • 99.02 (a)
NAT9 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Nat9 35
  • 86.34 (n)
  • 83.9 (a)
oppossum
(Monodelphis domestica)
Mammalia NAT9 36
  • 80 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia NAT9 36
  • 73 (a)
OneToOne
chicken
(Gallus gallus)
Aves NAT9 35
  • 73.77 (n)
  • 73.1 (a)
NAT9 36
  • 61 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia NAT9 36
  • 64 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia nat9 35
  • 67.91 (n)
  • 68.62 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC100004826 35
  • 63.28 (n)
  • 57.87 (a)
nat9 36
  • 53 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP007378 35
  • 49.49 (n)
  • 44.9 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG11539 35
  • 54.32 (n)
  • 50.26 (a)
CG11539 36
  • 47 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea Y67D2.5 35
  • 52.11 (n)
  • 45.26 (a)
Y67D2.5 36
  • 41 (a)
OneToOne
thale cress
(Arabidopsis thaliana)
eudicotyledons AT2G04845 35
  • 55.97 (n)
  • 49.73 (a)
bread mold
(Neurospora crassa)
Ascomycetes NCU03760 35
  • 47.92 (n)
  • 44.89 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes SPBC577.03c 35
  • 52.19 (n)
  • 52 (a)
Species with no ortholog for NAT9:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for NAT9 Gene

ENSEMBL:
Gene Tree for NAT9 (if available)
TreeFam:
Gene Tree for NAT9 (if available)

Paralogs for NAT9 Gene

No data available for Paralogs for NAT9 Gene

Variants for NAT9 Gene

Sequence variations from dbSNP and Humsavar for NAT9 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs12797 -- 74,770,854(-) GCACC(C/T)TATGG utr-variant-3-prime, nc-transcript-variant
rs878905 -- 74,773,272(-) GACTG(C/T)CCTCC intron-variant
rs878906 -- 74,773,195(-) TTGGA(A/G)TTTTG intron-variant
rs878907 -- 74,773,555(-) CCACT(C/T)CCCCT intron-variant
rs880827 -- 74,771,296(+) TCACA(C/T)GGACC utr-variant-3-prime, nc-transcript-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for NAT9 Gene

Variant ID Type Subtype PubMed ID
nsv908743 CNV Loss 21882294

Variation tolerance for NAT9 Gene

Residual Variation Intolerance Score: 35.57% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.13; 75.61% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for NAT9 Gene

HapMap Linkage Disequilibrium report
NAT9

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NAT9 Gene

Disorders for NAT9 Gene

MalaCards: The human disease database

(4) MalaCards diseases for NAT9 Gene - From: DISEASES

Disorder Aliases PubMed IDs
conjunctival folliculosis
  • acute follicular conjunctivitis
ophthalmia neonatorum
  • gonococcal conjunctivitis
germ cell and embryonal cancer
inclusion conjunctivitis
  • inclusion blenorrhea
- elite association
Search NAT9 in MalaCards View complete list of genes associated with diseases

Relevant External Links for NAT9

Genetic Association Database (GAD)
NAT9
Human Genome Epidemiology (HuGE) Navigator
NAT9
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
NAT9
genes like me logo Genes that share disorders with NAT9: view

No data available for UniProtKB/Swiss-Prot and Genatlas for NAT9 Gene

Publications for NAT9 Gene

  1. Investigation of the chromosome 17q25 PSORS2 locus in atopic dermatitis. (PMID: 16374479) Morar N. … Moffatt M.F. (J. Invest. Dermatol. 2006) 23 67
  2. A putative RUNX1 binding site variant between SLC9A3R1 and NAT9 is associated with susceptibility to psoriasis. (PMID: 14608357) Helms C. … Bowcock A.M. (Nat. Genet. 2003) 2 67
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 67
  4. Next-generation sequencing to generate interactome datasets. (PMID: 21516116) Yu H. … Vidal M. (Nat. Methods 2011) 67
  5. A directed protein interaction network for investigating intracellular signal transduction. (PMID: 21900206) Vinayagam A. … Wanker E.E. (Sci Signal 2011) 67

Products for NAT9 Gene

Sources for NAT9 Gene

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