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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NAT6 Gene

protein-coding   GIFtS: 47
GCID: GC03M050333

N-Acetyltransferase 6 (GCN5-Related)

(Previous name: N-acetyltransferase 6)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
N-Acetyltransferase 6 (GCN5-Related)1 2     FUS-22
FUS22 3 5     EC 2.3.1.-3
N-Acetyltransferase 61 2     Protein Fus-23
Protein Fusion-22 3     

External Ids:    HGNC: 302521   Entrez Gene: 241422   Ensembl: ENSG000002434777   OMIM: 6070735   UniProtKB: Q930153   

Export aliases for NAT6 gene to outside databases

Previous GC identifers: GC03M050293 GC03M050300 GC03M050308


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NAT6 Gene:
This gene encodes a member of the N-acetyltransferase family. N-acetyltransferases modify proteins by transferring
acetyl groups from acetyl CoA to the N-termini of protein substrates. The encoded protein is a cytoplasmic
N-acetyltransferase with a substrate specificity for proteins with an N-terminal methionine. This gene is located
in the tumor suppressor gene region on chromosome 3p21.3 and the encoded protein may play a role in cancer.
Alternatively spliced transcript variants encoding multiple isoforms have been observed. This gene overlaps and
is on the same strand as hyaluronoglucosaminidase 3, and some transcripts of each gene share a portion of the
first exon. (provided by RefSeq, Jan 2011)

GeneCards Summary for NAT6 Gene: 
NAT6 (N-acetyltransferase 6 (GCN5-related)) is a protein-coding gene. Diseases associated with NAT6 include mucopolysaccharidosis type ix, and alveolar soft part sarcoma. GO annotations related to this gene include N-acetyltransferase activity.

UniProtKB/Swiss-Prot: NAT6_HUMAN, Q93015
Function: Seems to be involved in N-acetylation. Acts on peptides with a N-terminal Met followed by Asp/Glu/Asn.
May act as a tumor suppressor




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NAT6 gene promoter:
         ATF-2   c-Jun   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for NAT6

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NAT6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p21.3   Ensembl cytogenetic band:  3p21.31   HGNC cytogenetic band: 3p21.3

NAT6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NAT6 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M050333:  view genomic region     (about GC identifiers)

Start:
50,333,833 bp from pter      End:
50,336,852 bp from pter
Size:
3,020 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NAT6_HUMAN, Q93015 (See protein sequence)
Recommended Name: N-acetyltransferase 6  
Size: 286 amino acids; 31445 Da
Subcellular location: Cytoplasm
Secondary accessions: Q93014
Alternative splicing: 2 isoforms:  Q93015-1   Q93015-2   

Explore the universe of human proteins at neXtProt for NAT6: NX_Q93015

Explore proteomics data for NAT6 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q93015

  • NAT6 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NAT6 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001186945.1  NP_001186947.1  NP_036323.2  

    ENSEMBL proteins: 
     ENSP00000346927   ENSP00000391893   ENSP00000410610   ENSP00000400559   ENSP00000388316  
     ENSP00000391158   ENSP00000413623  

    Human Recombinant Protein Products for NAT6: 
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    OriGene Purified Protein for NAT6
    OriGene Protein Over-expression Lysate for NAT6
    OriGene MassSpec for NAT6 
    OriGene Custom Protein Services for NAT6
    GenScript Custom Purified and Recombinant Proteins Services for NAT6
    Novus Biologicals NAT6 Proteins
    Novus Biologicals NAT6 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    ProSpec Recombinant Protein for NAT6
    Cloud-Clone Corp. Proteins for NAT6 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA--
    GO:0005739mitochondrion IDA--

    NAT6 for ontologies           About GeneDecksing



    NAT6 Antibody Products: 
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    ThermoFisher Antibodies for NAT6
    LSBio Antibodies in human, mouse, rat for NAT6 

    Assay Products for NAT6: 
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    GenScript Custom Assay Services for NAT6
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for NAT6 
    Cloud-Clone Corp. CLIAs for NAT6


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR000182 GNAT_dom
     IPR016181 Acyl_CoA_acyltransferase

    Graphical View of Domain Structure for InterPro Entry Q93015

    ProtoNet protein and cluster: Q93015

    1 Blocks protein domain: IPB000182 GCN5-related N-acetyltransferase

    UniProtKB/Swiss-Prot: NAT6_HUMAN, Q93015
    Similarity: Belongs to the acetyltransferase family
    Similarity: Contains 1 N-acetyltransferase domain


    NAT6 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NAT6_HUMAN, Q93015
    Function: Seems to be involved in N-acetylation. Acts on peptides with a N-terminal Met followed by Asp/Glu/Asn.
    May act as a tumor suppressor

         Enzyme Number (IUBMB): EC 2.3.1.-1

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008080N-acetyltransferase activity IEA--
         
    NAT6 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for NAT6 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for NAT6

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NAT6 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NAT6 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NAT6
    4 QIAGEN miScript miRNA Assays for microRNAs that regulate NAT6:
    hsa-miR-4303 hsa-miR-3157-5p hsa-miR-3921 hsa-miR-874
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for NAT6
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NAT6

    Gene Editing
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    Sirion Biotech Customized adenovirus for overexpression of NAT6

    Clone
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    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for NAT6 (see all 8)
    OriGene ORF clones in mouse, rat for NAT6
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): NAT6 (NM_001200018)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NAT6
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NAT6
    Sirion Biotech Customized lentivirus for stable overexpression of NAT6 
                         Customized lentivirus expression plasmids for stable overexpression of NAT6 

    Cell Line
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    Search LifeMap BioReagents cell lines for NAT6
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NAT6


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NAT6

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    4 Interacting proteins for NAT6 (Q930153 ENSP000003469274) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    EMG1Q929793I2D: score=3 
    SUSD4Q5VX713I2D: score=1 
    FAM107BENSP000001817964STRING: ENSP00000181796
    --ENSP000002614064STRING: ENSP00000261406
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NAT6

    1 HMDB Compound for NAT6    About this table
    CompoundSynonyms CAS #PubMed Ids
    4-Hydroxyphenylacetyl-CoA[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-[[hydroxy-[hydroxy-[3-hydroxy-3-[2-[2-[2-(4-hydroxyphenyl)acetyl]sulfanylethylcarbamoyl]ethylcarbamoyl]-2,2-dimethyl-propoxy]phosphoryl]oxy-phosphoryl]oxymethyl]oxolan-3-yl]oxyphosphonic acid 117411-05-9--

    Search CenterWatch for drugs/clinical trials and news about NAT6

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NAT6 gene (3 alternative transcripts): 
    NM_001200016.1  NM_001200018.1  NM_012191.3  

    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000354862(uc003czj.3) ENST00000417393(uc003czi.3) ENST00000443094(uc003czk.4)
    ENST00000443842 ENST00000450489 ENST00000442620 ENST00000452674
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NAT6
    4 QIAGEN miScript miRNA Assays for microRNAs that regulate NAT6:
    hsa-miR-4303 hsa-miR-3157-5p hsa-miR-3921 hsa-miR-874
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for NAT6
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NAT6
    Clone
    Products:
         
    OriGene clones in human, mouse for NAT6 (see all 8)
    OriGene ORF clones in mouse, rat for NAT6
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): NAT6 (NM_001200018)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NAT6
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NAT6
    Sirion Biotech Customized lentivirus for stable overexpression of NAT6 
                         Customized lentivirus expression plasmids for stable overexpression of NAT6 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for NAT6
    OriGene qSTAR qPCR primer pairs in human, mouse for NAT6
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NAT6
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NAT6
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NAT6

    24/510 AceView cDNA sequences (see all 510):

    AI584127 AA594445 BM673924 BE327260 AI583621 AF502911 AI003352 BU621396 
    BU952179 AF502910 CR595994 AA948544 BE563312 AW410513 BM989194 NM_003549 
    BE264254 BM841031 AW059669 BQ927332 AF040710 AI290004 BX283184 NM_006764 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NAT6 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    NAT6 Expression
    About this image


    See NAT6 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NAT6

    UniProtKB/Swiss-Prot: NAT6_HUMAN, Q93015
    Tissue specificity: Strongly expressed in heart and skeletal muscle, followed by brain and pancreas, with weak
    expression in kidney, liver, and lung and no expression in placenta

        SABiosciences Custom PCR Arrays for NAT6
    Primer
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    OriGene qPCR primer pairs and template standards for NAT6
    OriGene qSTAR qPCR primer pairs in human, mouse for NAT6
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NAT6
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NAT6
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NAT6
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NAT6

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for NAT6 gene from 5/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nat61 , 5 N-acetyltransferase 61, 5 81.14(n)1
    73.36(a)1
      9 (58.18 cM)5
    564411  NM_019750.31  NP_062724.11 
     1075788875 
    lizard
    (Anolis carolinensis)
    Reptilia NAT66
    Uncharacterized protein
    47(a)
    1 ↔ 1
    2(149872157-149873095)
    zebrafish
    (Danio rerio)
    Actinopterygii NAT66
    N-acetyltransferase 6 (GCN5-related)
    40(a)
    1 ↔ 1
    8(27225193-27229241)
    fruit fly
    (Drosophila melanogaster)
    Insecta CG84816
    --
    32(a)
    1 ↔ 1
    3R(5593573-5595749)
    worm
    (Caenorhabditis elegans)
    Secernentea C56G2.156
    Protein C56G2.15
    29(a)
    1 ↔ 1
    III(6366581-6367822)


    ENSEMBL Gene Tree for NAT6 (if available)
    TreeFam Gene Tree for NAT6 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NAT6 gene
    1 SIMAP similar gene for NAT6 using alignment to 3 protein entries:     NAT6_HUMAN (see all proteins):
    HYAL3

    NAT6 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    2 SNPs in NAT6 are shown    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0142254
    Non-small cell lung cancer cell lines4--see VAR_0142252 T S mis40--------
    VAR_0142244
    Non-small cell lung cancer cell lines4--see VAR_0142242 R S mis40--------

    HapMap Linkage Disequilibrium report for NAT6 (50333833 - 50336852 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/12 variations for NAT6 (see all 12):    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv5132n71CNV Loss21882294
    nsv523662CNV Loss19592680
    nsv876770CNV Loss21882294
    nsv3813CNV Loss18451855
    dgv5131n71CNV Loss21882294
    nsv876769CNV Loss21882294
    nsv834692CNV Loss17160897
    nsv470561CNV Loss18288195
    nsv834693CNV Loss17160897
    nsv523560CNV Loss19592680

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing NAT6
    DNA2.0 Custom Variant and Variant Library Synthesis for NAT6

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 607073    OMIM disorders: --

    7 diseases for NAT6:    About MalaCards
    mucopolysaccharidosis type ix    alveolar soft part sarcoma    nasopharyngitis    lung cancer
    sarcoma    esophagitis    arthritis


    NAT6 for disorders           About GeneDecksing

    2 Novoseek inferred disease relationships for NAT6 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    cancer 0.79 2 10644992 (1)
    tumors 0 3 15276206 (1), 15036368 (1)

    Genetic Association Database (GAD): NAT6
    Human Genome Epidemiology (HuGE) Navigator: NAT6 (4 documents)

    Export disorders for NAT6 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NAT6 gene, integrated from 9 sources (see all 20):
    (articles sorted by number of sources associating them with NAT6)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. (PubMed id 11085536)1, 2, 3 Lerman M.I. and Minna J.D. (2000)
    2. The putative tumour suppressor Fus-2 is an N-acetyltransferase. (PubMed id 10644992)1, 2, 9 Zegerman P.... Kouzarides T. (2000)
    3. Characterization of a new SNP c767A/T (Arg222Trp) in the candidate TSG FUS2 on human chromosome 3p21.3: prevalence in Asian populations and analysis of association with nasopharyngeal cancer. (PubMed id 15036368)1, 4, 9 Duh F.M....Lerman M.I. (2004)
    4. A gene-based risk score for lung cancer susceptibilit y in smokers and ex-smokers. (PubMed id 19789190)1, 4 Young R.P....Gamble G.D. (2009)
    5. The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)1, 2 Muzny D.M....Gibbs R.A. (2006)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Characterization of the murine hyaluronidase gene region reveals complex organization and cotranscription of Hyal1 with downstream genes, Fus2 and Hyal3. (PubMed id 11929860)1, 3 Shuttleworth T.L....Triggs-Raine B.L. (2002)
    8. Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
    9. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    10. Expression of candidate chromosome 3p21.3 tumor suppressor genes and down-regulation of BLU in some esophageal squamous cell carcino mas. (PubMed id 15885884)1 Yi Lo P.H....Lung M.L. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 24142 HGNC: 30252 AceView: HYAL3 Ensembl:ENSG00000243477 euGenes: HUgn24142
    ECgene: NAT6 H-InvDB: NAT6

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NAT6 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for NAT6 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NAT6 gene:
    Search GeneIP for patents involving NAT6

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
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     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
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     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
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     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for NAT6   OriGene RNAi products in human, mouse, rat for NAT6  
     OriGene qPCR primer pairs and template standards for NAT6   OriGene Protein Over-expression Lysate for NAT6  
     OriGene MassSpec something-or-other for NAT6   OriGene clones in human, mouse for NAT6  
     OriGene qSTAR qPCR primer pairs in human, mouse for NAT6   OriGene Purified Protein for NAT6  
     OriGene ORF clones in mouse, rat for NAT6   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for NAT6   OriGene Custom Protein Services for NAT6  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NAT6
     QIAGEN SeqTarget long-range PCR primers for resequencing NAT6
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NAT6
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NAT6
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NAT6
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NAT6
     GenScript Custom Purified and Recombinant Proteins Services for NAT6 GenScript cDNA clones with any tag delivered in your preferred vector for NAT6
     GenScript Custom Assay Services for NAT6 GenScript Custom Superior Antibodies Services for NAT6
     GenScript Custom overexpressing Cell Line Services for NAT6 CloneReady with Over 120,000 Genes
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     Search for Antibodies & Assays

     Regulatory tfbs in NAT6 promoter
     Search Chromatin IP Primers for NAT6
     RT2 qPCR Primer Assay in human, mouse, rat NAT6
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     SABiosciences Custom PCR Arrays for NAT6
     Search Tocris compounds for NAT6
     Browse Sino Biological Proteins and Antibodies
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     Search Sino Biological for antibodies, proteins & pathways
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     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
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     See all of Abcam's Antibodies, Kits and Proteins for NAT6
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     Abcam protocols and scientific support
     Recombinant Protein for NAT6




     Proteins for NAT6
     Antibodies for NAT6
     ELISAs for NAT6
     CLIAs for NAT6
     Search LifeMap BioReagents cell lines for NAT6
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
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     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NAT6
     Browse SwitchGear 3'UTR luciferase reporter plasmids for NAT6
     Browse SwitchGear Promoter luciferase reporter plasmids for NAT6
     ThermoFisher Antibodies for NAT6
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NAT6
     inGenious Targeting Laboratory - Custom generated mouse model solutions for NAT6
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for NAT6
    Customized:
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     lentivirus expression plasmids for stable overexpression of NAT6
     adenovirus for overexpression of NAT6
     LSBio Antibodies in human, mouse, rat for NAT6
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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    (GIFtS: 73)
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