NAT16 Gene
protein-coding GIFtS: 37
GCID: GC07M100814
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N-acetyltransferase 16 (GCN5-related, putative)(Previous name: chromosome 7 open reading frame 52 )
(Previous symbol: C7orf52)
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Aliases
for NAT16 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| N-Acetyltransferase 16 (GCN5-Related, Putative)1 2 | | Putative N-Acetyltransferase 162 | | C7orf521 2 3 | | Putative N-Acetyltransferase C7orf522 | | FLJ392371 | | EC 2.3.1.-3 | | Chromosome 7 Open Reading Frame 521 | | |
Export aliases for NAT16 gene to outside databases |
Summaries
for NAT16 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for NAT16 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007933.15 NT_079596.2
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for NAT16
Other transcription factors
Search SABiosciences Chromatin IP Primers for NAT16
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NAT16 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7q22.1 Ensembl cytogenetic band: 7q22.1 HGNC cytogenetic band: 7q22.1NAT16 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07M100814: view genomic region
(about GC identifiers)
Start:
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100,813,774 bp from pter |
End:
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100,823,557 bp from pter |
Size:
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9,784 bases |
Orientation:
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minus strand |
1 alternative location:
| Chr7-,CRA_TCAG 100,172,161-100,181,944 |
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Proteins
for NAT16 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: NAT16_HUMAN, Q8N8M0 (See
protein sequence)Recommended Name: Putative N-acetyltransferase 16 Size: 369 amino acids; 40521 Da
Secondary accessions: Q8NDR1Explore the universe of human proteins at neXtProt for NAT16: NX_Q8N8M0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8N8M0
NAT16 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_940973.2
ENSEMBL proteins: ENSP00000300303 ENSP00000395125 ENSP00000391769 ENSP00000394435
Human Recombinant Protein Products:
NAT16 Antibody Products:
Assay Products for NAT16: |
Protein
Domains /
Families
for NAT16 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NAT16 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8N8M0ProtoNet protein and cluster: Q8N8M0 UniProtKB/Swiss-Prot: NAT16_HUMAN, Q8N8M0Similarity: Contains 1 N-acetyltransferase domain |
Function
for NAT16 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Enzyme Number (IUBMB): EC 2.3.1.-1
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NAT16
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NAT16
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for NAT16 | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NAT16 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NAT16 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NAT16 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008080 | N-acetyltransferase activity |
IEA | -- |
NAT16 for ontologies About GeneDecksing
|
Pathways & Interactions
for NAT16 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NAT16
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
2 Interacting proteins for NAT16 (ENSP000003003034) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for NAT16 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for NAT16
Search CenterWatch for drugs/clinical trials and news about NAT16
|
Transcripts
for NAT16 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for NAT16 gene: NM_198571.2 Unigene Cluster for NAT16: N-acetyltransferase 16 (GCN5-related, putative) Hs.213044 [show with all ESTs]Unigene Representative Sequence: NM_1985714 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000300303(uc003uxy.2 uc003uxz.2) ENST00000455377 ENST00000444446
ENST00000443096(uc003uya.1 uc003uyb.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NAT16
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NAT16
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for NAT16 | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NAT16 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NAT16 |
Additional cDNA sequence: AK092119.1 AK096556.1 AL831911.1 BC037583.1 BC104841.1 5 DOTS entries: DT.65288621 DT.100018599 DT.97834535 DT.95355329 DT.121126563 20 AceView cDNA sequences: BQ640011 AK092119 BV185387 BG327091 NM_198571 AK096556 BI916227 AX747364 BE218557 AI912271 AL831911 BM727073 AI914085 BX119484 BC037583 BF346450 BE549627 BM726057 H83792 H83934
GeneLoc Exon Structure
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Expression
for NAT16 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| NAT16 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CGAGACCCCT
About this image
See NAT16 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NAT16
SOURCE GeneReport for Unigene cluster: Hs.213044
SABiosciences Custom PCR Arrays for NAT16
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NAT16
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat NAT16 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NAT16 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NAT16 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NAT16 |
Orthologs
for NAT16 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for NAT16 gene from 2/5 species (see all 5) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
African clawed frog
(Xenopus laevis) |
Amphibia |
BQ736518.12 |
-- |
73.45(n) |
|
BQ736518.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
LOC1000032451 |
putative N-acetyltransferase C7orf52-like |
59.4(n)
55.45(a) |
|
100003245 XM_001342820.1 XP_001342856.1 |
Species with no ortholog for NAT16
ENSEMBL Gene Tree for NAT16 (if available)
TreeFam Gene Tree for NAT16 (if available) |
Paralogs
for NAT16 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for NAT16 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for NAT16 (100813774 - 100823557 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for NAT16: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NAT16 |
|
Disorders
/ Diseases
for NAT16 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for NAT16 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for NAT16 gene integrated from 9 sources:
(articles sorted by number of sources associating them with NAT16) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The ubiquitin ligase XIAP recruits LUBAC for NOD2 sign aling in inflammation and innate immunity. (PubMed id 22607974)1 Damgaard R.B....Gyrd-Hansen M. (2012)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- The DNA sequence of human chromosome 7. (PubMed id 12853948)2 Hillier L.W.... Wilson R.K. (2003)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)
|
External Searches for NAT16 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing NAT16 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing NAT16 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NAT16 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for NAT16 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for NAT16 gene:
Search GeneIP for patents involving NAT16
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for NAT16 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for NAT16 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NAT16 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NAT16 | | | OriGene Protein Over-expression Lysate for NAT16 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for NAT16 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NAT16 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NAT16 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for NAT16 | | OriGene Custom Protein Services for NAT16 | | | OriGene Custom Immunoassay Development | | |
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 | | | NAT16 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NAT16 |
|  |  |  | | | | Search ThermoFisher Antibodies for NAT16 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NAT16 |
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