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Aliases for NAT14 Gene

Aliases for NAT14 Gene

  • N-Acetyltransferase 14 (GCN5-Related, Putative) 2 3
  • K562 Cells-Derived Leucine Zipper-Like Protein 1 2 3
  • K562 Cell-Derived Leucine-Zipper-Like Protein 1 3 4
  • N-Acetyltransferase 14 2 3
  • KLP1 3 4
  • K562 Cells-Derived Leucine-Zipper-Like Protein 1 3
  • EC 2.3.1.- 4
  • EC 2.3.1 63

External Ids for NAT14 Gene

Summaries for NAT14 Gene

GeneCards Summary for NAT14 Gene

NAT14 (N-Acetyltransferase 14 (GCN5-Related, Putative)) is a Protein Coding gene. Among its related pathways are Biological oxidations. GO annotations related to this gene include N-acetyltransferase activity.

UniProtKB/Swiss-Prot for NAT14 Gene

  • Probable acetyltransferase that binds the 5-GGACTACAG-3 sequence of coproporphyrinogen oxidase promoter. Able to activate transcription of a reporter construct in vitro

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NAT14 Gene

Genomics for NAT14 Gene

Genomic Location for NAT14 Gene

55,485,004 bp from pter
55,487,568 bp from pter
2,565 bases
Plus strand

Genomic View for NAT14 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for NAT14 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NAT14 Gene

Regulatory Elements for NAT14 Gene

Proteins for NAT14 Gene

  • Protein details for NAT14 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    N-acetyltransferase 14
    Protein Accession:
    Secondary Accessions:
    • Q8TDY7
    • Q9NS72

    Protein attributes for NAT14 Gene

    206 amino acids
    Molecular mass:
    21650 Da
    Quaternary structure:
    No Data Available

neXtProt entry for NAT14 Gene

Proteomics data for NAT14 Gene at MOPED

Selected DME Specific Peptides for NAT14 Gene

Post-translational modifications for NAT14 Gene

No Post-translational modifications

Other Protein References for NAT14 Gene

Domains for NAT14 Gene

Protein Domains for NAT14 Gene

Suggested Antigen Peptide Sequences for NAT14 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 N-acetyltransferase domain.:
    • Q8WUY8
  • Belongs to the camello family.:
    • Q8WUY8
genes like me logo Genes that share domains with NAT14: view

No data available for Gene Families for NAT14 Gene

Function for NAT14 Gene

Molecular function for NAT14 Gene

UniProtKB/Swiss-Prot Function: Probable acetyltransferase that binds the 5-GGACTACAG-3 sequence of coproporphyrinogen oxidase promoter. Able to activate transcription of a reporter construct in vitro

Enzyme Numbers (IUBMB) for NAT14 Gene

Gene Ontology (GO) - Molecular Function for NAT14 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0008080 N-acetyltransferase activity IEA --
genes like me logo Genes that share ontologies with NAT14: view

Phenotypes for NAT14 Gene

GenomeRNAi human phenotypes for NAT14:
genes like me logo Genes that share phenotypes with NAT14: view

miRNA for NAT14 Gene

miRTarBase miRNAs that target NAT14

No data available for Animal Models , Transcription Factor Targeting and HOMER Transcription for NAT14 Gene

Localization for NAT14 Gene

Subcellular locations from UniProtKB/Swiss-Prot for NAT14 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

Jensen Localization Image for NAT14 Gene COMPARTMENTS Subcellular localization image for NAT14 gene
Compartment Confidence
nucleus 5
plasma membrane 2
cytosol 1
endoplasmic reticulum 1
extracellular 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for NAT14 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus NAS 10873651
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with NAT14: view

Pathways for NAT14 Gene

SuperPathways for NAT14 Gene

Superpath Contained pathways
1 Biological oxidations
genes like me logo Genes that share pathways with NAT14: view

Pathways by source for NAT14 Gene

1 BioSystems pathway for NAT14 Gene

Gene Ontology (GO) - Biological Process for NAT14 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006352 DNA-templated transcription, initiation NAS 10873651
GO:0045893 positive regulation of transcription, DNA-templated NAS 10873651
genes like me logo Genes that share ontologies with NAT14: view

Compounds for NAT14 Gene

(1) HMDB Compounds for NAT14 Gene

Compound Synonyms Cas Number PubMed IDs
Coproporphyrinogen III
  • 3,8,13,17-tetramethyl-5,10,15,20,22,24-hexahydroporphyrin-2,7,12,18-tetrapropanoate
genes like me logo Genes that share compounds with NAT14: view

Transcripts for NAT14 Gene

mRNA/cDNA for NAT14 Gene

Unigene Clusters for NAT14 Gene

N-acetyltransferase 14 (GCN5-related, putative):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for NAT14 Gene

No ASD Table

Relevant External Links for NAT14 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for NAT14 Gene

mRNA expression in normal human tissues for NAT14 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for NAT14 Gene

SOURCE GeneReport for Unigene cluster for NAT14 Gene Hs.31854

mRNA Expression by UniProt/SwissProt for NAT14 Gene

Tissue specificity: Expressed in K-562 and HeLa cell lines and in brain.
genes like me logo Genes that share expressions with NAT14: view

No data available for mRNA differential expression in normal tissues for NAT14 Gene

Orthologs for NAT14 Gene

This gene was present in the common ancestor of chordates.

Orthologs for NAT14 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia NAT14 35
  • 99.84 (n)
  • 99.51 (a)
NAT14 36
  • 100 (a)
(Bos Taurus)
Mammalia NAT14 35
  • 88.83 (n)
  • 96.12 (a)
NAT14 36
  • 96 (a)
(Canis familiaris)
Mammalia NAT14 35
  • 88.51 (n)
  • 95.63 (a)
NAT14 36
  • 96 (a)
(Mus musculus)
Mammalia Nat14 35
  • 87.06 (n)
  • 95.15 (a)
Nat14 16
Nat14 36
  • 95 (a)
(Rattus norvegicus)
Mammalia Nat14 35
  • 86.41 (n)
  • 93.69 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia nat14 35
  • 58.03 (n)
  • 51.81 (a)
(Danio rerio)
Actinopterygii NAT14 36
  • 28 (a)
Species with no ortholog for NAT14:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for NAT14 Gene

Gene Tree for NAT14 (if available)
Gene Tree for NAT14 (if available)

Paralogs for NAT14 Gene

No data available for Paralogs for NAT14 Gene

Variants for NAT14 Gene

Sequence variations from dbSNP and Humsavar for NAT14 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs3745450 -- 55,485,572(-) CTTCC(C/T)AGATC intron-variant
rs3745451 -- 55,485,536(-) CCAAG(A/C)GAGGA intron-variant
rs73608725 -- 55,485,092(+) CACAG(C/T)TCGGT upstream-variant-2KB
rs75176024 -- 55,485,317(+) GGGGC(A/G)CTGGG intron-variant
rs77617762 -- 55,485,312(+) GGGAG(C/G)GGGCG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for NAT14 Gene

Variant ID Type Subtype PubMed ID
nsv912457 CNV Loss 21882294
nsv912463 CNV Loss 21882294
nsv912473 CNV Loss 21882294
nsv912478 CNV Loss 21882294
dgv4022n71 CNV Loss 21882294
dgv4023n71 CNV Loss 21882294
dgv4024n71 CNV Loss 21882294
nsv458833 CNV Loss 19166990
nsv912486 CNV Loss 21882294
dgv4025n71 CNV Loss 21882294
nsv2552 CNV Insertion 18451855
nsv912489 CNV Loss 21882294

Relevant External Links for NAT14 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NAT14 Gene

Disorders for NAT14 Gene

No disorders were found for NAT14 Gene.

No data available for UniProtKB/Swiss-Prot for NAT14 Gene

Publications for NAT14 Gene

  1. Cloning of a coproporphyrinogen oxidase promoter regulatory element binding protein. (PMID: 10873651) Takahashi S. … Hayashi N. (Biochem. Biophys. Res. Commun. 2000) 2 3 4 23
  2. Genomic structure and regulation of a novel human gene, Klp1. (PMID: 11779635) Takahashi S. … Sasaki T. (Biochim. Biophys. Acta 2001) 3 4 23
  3. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Transcriptome analysis of human gastric cancer. (PMID: 16341674) Oh J.H. … Kim N.S. (Mamm. Genome 2005) 3

Products for NAT14 Gene

Sources for NAT14 Gene

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