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Aliases for NAPSB Gene

Aliases for NAPSB Gene

  • Napsin B Aspartic Peptidase, Pseudogene 2 3
  • Napsin A Aspartic Peptidase Pseudogene 3
  • Napsin B Aspartic Peptidase Pseudogene 3
  • Napsin B Pseudogene 3
  • Napsin-A Pseudogene 3
  • Pronapsin B 3
  • Napsin 2 3
  • NAPSBP 3
  • NAP1L 3
  • NAP2 3
  • NAPB 3

External Ids for NAPSB Gene

Previous GeneCards Identifiers for NAPSB Gene

  • GC19M055530
  • GC19M055531
  • GC19M050837
  • GC19M047175

Summaries for NAPSB Gene

GeneCards Summary for NAPSB Gene

NAPSB (Napsin B Aspartic Peptidase, Pseudogene) is a Pseudogene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NAPSB Gene

Genomics for NAPSB Gene

Regulatory Elements for NAPSB Gene

Genomic Location for NAPSB Gene

50,333,796 bp from pter
50,344,767 bp from pter
10,972 bases
Minus strand

Genomic View for NAPSB Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for NAPSB Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NAPSB Gene

Proteins for NAPSB Gene

Post-translational modifications for NAPSB Gene

No Post-translational modifications

No data available for DME Specific Peptides for NAPSB Gene

Domains for NAPSB Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for NAPSB Gene

Function for NAPSB Gene

Animal Model Products

miRNA for NAPSB Gene

miRTarBase miRNAs that target NAPSB

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for NAPSB Gene

Localization for NAPSB Gene

Subcellular locations from

Jensen Localization Image for NAPSB Gene COMPARTMENTS Subcellular localization image for NAPSB gene
Compartment Confidence
endoplasmic reticulum 3
lysosome 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for NAPSB Gene

Pathways for NAPSB Gene

SuperPathways for NAPSB Gene

No Data Available

Interacting Proteins for NAPSB Gene

Gene Ontology (GO) - Biological Process for NAPSB Gene


No data available for Pathways by source for NAPSB Gene

Transcripts for NAPSB Gene

Unigene Clusters for NAPSB Gene

Napsin B aspartic peptidase, pseudogene:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for NAPSB Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7a · 7b ^ 8
SP1: - - -
SP3: - - - - -

Relevant External Links for NAPSB Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for NAPSB Gene

mRNA expression in normal human tissues for NAPSB Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for NAPSB Gene

This gene is overexpressed in Spleen (11.0), Whole Blood (9.0), and Small Intestine - Terminal Ileum (4.3).

Protein differential expression in normal tissues for NAPSB Gene

This gene is overexpressed in Lung (65.1).

Integrated Proteomics: protein expression from for NAPSB Gene

SOURCE GeneReport for Unigene cluster for NAPSB Gene Hs.636624

genes like me logo Genes that share expressions with NAPSB: view

Expression partners for NAPSB Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for NAPSB Gene

Orthologs for NAPSB Gene

Evolution for NAPSB Gene

Gene Tree for NAPSB (if available)
Gene Tree for NAPSB (if available)

No data available for Orthologs for NAPSB Gene

Paralogs for NAPSB Gene

No data available for Paralogs for NAPSB Gene

Variants for NAPSB Gene

Sequence variations from dbSNP and Humsavar for NAPSB Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs590653 -- 50,343,174(-) aagac(C/T)agctt intron-variant
rs591161 -- 50,343,024(-) tatga(C/T)tgagc intron-variant
rs607307 -- 50,341,764(-) CCCTG(C/T)GTGCT intron-variant
rs612302 -- 50,340,054(-) GGTTG(G/T)GTTAA intron-variant
rs613694 -- 50,340,962(+) tgcct(C/G)ggcct intron-variant

Structural Variations from Database of Genomic Variants (DGV) for NAPSB Gene

Variant ID Type Subtype PubMed ID
nsv523948 CNV Gain 19592680
dgv3976n71 CNV Loss 21882294
nsv2529 CNV Insertion 18451855

Relevant External Links for NAPSB Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NAPSB Gene

Disorders for NAPSB Gene

No disorders were found for NAPSB Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for NAPSB Gene

Publications for NAPSB Gene

  1. Pronapsin A and B gene expression in normal and malignant human lung and mononuclear blood cells. (PMID: 12151090) Cook M. … Kay J. (Biochim. Biophys. Acta 2002) 3 23
  2. Napsins: new human aspartic proteinases. Distinction between two closely related genes. (PMID: 9877162) Tatnell P.J. … Kay J. (FEBS Lett. 1998) 2 3
  3. Membrane-anchored aspartyl protease with Alzheimer's disease beta- secretase activity. (PMID: 10591213) Yan R. … Gurney M.E. (Nature 1999) 2 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Structural and phylogenetic comparison of napsin genes: the duplication, loss of function and human-specific pseudogenization of napsin B. (PMID: 23333608) Nishishita K. … Tsukuba T. (Gene 2013) 3

Products for NAPSB Gene

Sources for NAPSB Gene

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