NAPEPLD Gene
protein-coding GIFtS: 53
GCID: GC07M102742
|
|
N-acyl phosphatidylethanolamine phospholipase D
| |
Aliases
for NAPEPLD gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| N-Acyl Phosphatidylethanolamine Phospholipase D1 2 3 | | NAPE-Hydrolyzing Phospholipase D2 3 | | NAPE-PLD1 2 3 | | N-Acyl-Phosphatidylethanolamine-Hydrolyzing Phospholipase D2 | | FMP301 2 | | EC 3.1.4.543 | | C7orf181 3 | | EC 3.1.48 |
Export aliases for NAPEPLD gene to outside databasesPrevious GC identifers: GC07M102528 GC07M097103 |
Summaries
for NAPEPLD gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for NAPEPLD:
NAPEPLD is a phospholipase D type enzyme that catalyzes the release of N-acylethanolamine (NAE) fromN-acyl-phosphatidylethanolamine (NAPE) in the second step of the biosynthesis of N-acylethanolamine (Okamoto et al.,2004 (PubMed 14634025)).(supplied by OMIM, Oct 2008)
UniProtKB/Swiss-Prot: NAPEP_HUMAN, Q6IQ20Function: Hydrolyzes N-acyl-phosphatidylethanolamines (NAPEs) to produce N-acylethanolamines (NAEs) and phosphatidicacid. Responsible for the generation of anandamide (N-arachidonoylethanolamine), the ligand of cannabinoid andvanilloid receptors (By similarity)
|
Genomic Views
for NAPEPLD gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007933.15 NT_079596.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the NAPEPLD gene promoter:
TBP COUP-TF1 SRF SRF (504 AA) COUP HNF-4alpha2 AP-4 POU6F1 (c2) HNF-4alpha1 COUP-TF
Other transcription factors
Search SABiosciences Chromatin IP Primers for NAPEPLD
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NAPEPLD |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7q22.1 Ensembl cytogenetic band: 7q22.1 HGNC cytogenetic band: 7q22.1NAPEPLD Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07M102742: view genomic region
(about GC identifiers)
Start:
|
102,740,023 bp from pter |
End:
|
102,790,007 bp from pter |
Size:
|
49,985 bases |
Orientation:
|
minus strand |
1 alternative location:
| Chr7-,CRA_TCAG 102,100,389-102,149,935 |
|
Proteins
for NAPEPLD gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: NAPEP_HUMAN, Q6IQ20 (See
protein sequence)Recommended Name: N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D Size: 393 amino acids; 45596 Da
Cofactor: Binds 1 or 2 zinc ions per subunit (By similarity)
Subunit: Monomer (By similarity)
Subcellular location: Membrane (By similarity)
Secondary accessions: Q5CZ87 Q769K1Explore the universe of human proteins at neXtProt for NAPEPLD: NX_Q6IQ20
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6IQ20
4/7 DME Specific Peptides for NAPEPLD (Q6IQ20) (see all 7)
NAPEPLD Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001116310.1 NP_945341.3
ENSEMBL proteins: ENSP00000340093 ENSP00000407112 ENSP00000412376 ENSP00000419188 ENSP00000395138 ENSP00000392775 ENSP00000404391 ENSP00000414778 ENSP00000414364 Reactome Protein details: Q6IQ20
Human Recombinant Protein Products for NAPEPLD:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016020 | membrane |
IEA | -- |
NAPEPLD for ontologies About GeneDecksing
NAPEPLD Antibody Products:
Assay Products for NAPEPLD: |
Protein
Domains /
Families
for NAPEPLD gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NAPEPLD for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q6IQ20ProtoNet protein and cluster: Q6IQ20 UniProtKB/Swiss-Prot: NAPEP_HUMAN, Q6IQ20Similarity: Belongs to the NAPE-PLD family |
Function
for NAPEPLD gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: NAPEP_HUMAN, Q6IQ20Function: Hydrolyzes N-acyl-phosphatidylethanolamines (NAPEs) to produce N-acylethanolamines (NAEs) and phosphatidicacid. Responsible for the generation of anandamide (N-arachidonoylethanolamine), the ligand of cannabinoid andvanilloid receptors (By similarity)Catalytic activity: An N-acylphosphatidylethanolamine + H(2)O = an N-acylethanolamine + a 1,2-diacylglycerol3-phosphateEnzyme regulation: Activity is stimulated by divalent cations (By similarity) Enzyme Numbers (IUBMB): EC 3.1.42 EC 3.1.4.541
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004620 | phospholipase activity |
-- | -- | | GO:0008270 | zinc ion binding |
IEA | -- | | GO:0070290 | NAPE-specific phospholipase D activity |
IEA | -- |
NAPEPLD for ontologies About GeneDecksing
Phenotypes:
3 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Napepld):
NAPEPLD for phenotypes About GeneDecksing
Animal Models:
Mouse knock-outs for NAPEPLD: Napepldtm1.1Rpa Napepldtm1Crv Napepldtm1.2Itl
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NAPEPLD (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NAPEPLD (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): NAPEPLD (NM_198990) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NAPEPLD | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NAPEPLD |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NAPEPLD |
|
Pathways & Interactions
for NAPEPLD gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Acyl chain remodelling of PE | | | 2 | Biosynthesis of A2E, implicated in retinal degradation | | | 3 | Disease | | | 4 | Retinoid metabolism and transport | | | 5 | Defective OPN1LW causes CBP | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for NAPEPLD
1  GeneGo (Thomson Reuters) Pathway for NAPEPLD
4 
Reactome Pathways for NAPEPLD
NAPEPLD for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NAPEPLD
STRING Interaction
Network Preview (showing 5 interactants - click image to see 9)
5/28 Interacting proteins for NAPEPLD (Q6IQ203 ENSP000003400934) via UniProtKB, MINT, STRING, and/or I2D (see all 28)About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0009395 | phospholipid catabolic process |
IEA | -- |
NAPEPLD for ontologies About GeneDecksing
|
Drugs & Compounds
for NAPEPLD gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for NAPEPLD
10/1088 HMDB Compounds for NAPEPLD (see all 1088) About this table
| Compound | Synonyms |
CAS
# | PubMed Ids |
|---|
| PE(O-16:1(1Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) | 1-alkenyl-2-acyl-glycerophosphoethanolamine (see all 15) | -- | 12486725 | | PE(O-18:1(1Z)/20:4(5Z,8Z,11Z,14Z)) | 1-alkenyl-2-acyl-glycerophosphoethanolamine (see all 19) | 103597-60-0 | 12486725 | | PE(P-16:0e/0:0) | 2-azaniumylethyl [(2R)-3-[(E)-hexadec-1-enoxy]-2-hydroxy-propyl] phosphate;1-(1Z-hexadecenyl)-sn-glycero-3-phosphoethanolamine ;LysoPE(dm16:0e) | -- | 12486725 | | PE(P-16:0e/18:1(9Z)) | 2-(9Z-octadecanoyl)-1-hexadecyl-sn-glycero-3-phosphoethanolamine | -- | 12486725 | | Anandamide | Anandamide (20.4, n-6) (see all 13) | 94421-68-8 | -- | | PA(16:0/16:0) | Dipalmitoylphosphatidic acid (see all 25) | 7091-44-3 | -- | | PA(16:0/18:1(11Z)) | PA(16:0/18:1n7) (see all 10) | -- | -- | | PA(16:0/18:1(9Z)) | PA(16:0/18:1n9) (see all 10) | -- | -- | | PA(16:0/18:2(9Z,12Z)) | PA(34:2) (see all 10) | -- | -- | | PA(16:0e/18:0) | 2-octadecanoyl-1-hexadecyl-sn-glycero-3-phosphate ;PA(o-16:0/18:0) | -- | -- |
Search CenterWatch for drugs/clinical trials and news about NAPEPLD / NAPEP
|
Transcripts
for NAPEPLD gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for NAPEPLD gene (2 alternative transcripts): NM_001122838.1 NM_198990.4 Unigene Cluster for NAPEPLD: N-acyl phosphatidylethanolamine phospholipase D Hs.324271 [show with all ESTs]Unigene Representative Sequence: NM_00112283811 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000414118 ENST00000341533(uc003vbc.2 uc003vbe.2) ENST00000417955(uc003vbd.2 uc011klj.1)
ENST00000422589 ENST00000465647 ENST00000420631 ENST00000427257 ENST00000418294
ENST00000479761(uc003vbf.3) ENST00000425379 ENST00000455523
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NAPEPLD (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NAPEPLD (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): NAPEPLD (NM_198990) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NAPEPLD | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NAPEPLD |
Additional cDNA sequence: AB112352.1 AK000801.1 AK023244.1 AK304644.1 AY357337.1 BC037350.2 BC057294.1 BC071604.1 CR936639.1 12 DOTS entries: DT.100686975 DT.100670302 DT.99983730 DT.100710941 DT.101969415 DT.91798318 DT.102842703 DT.422759 DT.121073908 DT.121073766 DT.40131984 DT.86841791 24/108 AceView cDNA sequences (see all 108): AY357337 Z40218 BX091822 AW445108 AW072626 BU507368 CR615836 AI209134 BM148178 AA360843 AI460037 AA864799 AI369945 AA322501 AB112352 AI399802 BU169519 BG426843 BG742468 BX952200 CB962113 AA488956 AU132248 BF112206
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for NAPEPLD About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5 | ^ | 6 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | - | | - | | - | | | | | | | | | | | | | | |
| SP3: | | | | | | | - | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for NAPEPLD
|
Expression
for NAPEPLD gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| NAPEPLD expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCAGGGGTTA
About this image
See NAPEPLD Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NAPEPLD
SOURCE GeneReport for Unigene cluster: Hs.324271
SABiosciences Custom PCR Arrays for NAPEPLD
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NAPEPLD
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NAPEPLD | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NAPEPLD | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NAPEPLD | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NAPEPLD |
Orthologs
for NAPEPLD gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for NAPEPLD gene from 6/23 species (see all 23) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Napepld1 , 5 |
N-acyl phosphatidylethanolamine phospholipase D1, 5 |
83.97(n)1
89.31(a)1 |
|
5 (9.97 cM)5
2428641 NM_178728.51 NP_848843.11
216629015 |
chicken
(Gallus gallus) |
Aves |
NAPEPLD1 |
N-acyl phosphatidylethanolamine phospholipase D |
76.69(n)
80.98(a) |
|
417719 NM_001030730.1 NP_001025901.1 |
lizard
(Anolis carolinensis) |
Reptilia |
NAPEPLD6 |
-- |
77(a) |
1 ↔ 1 |
5(95316212-95332540) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.339582 |
Xenopus laevis transcribed sequence with weak similarity more |
78.28(n) |
|
CA793413.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufc56b112 |
wufc56b11 |
74.71(n) |
|
325131 57051008 |
worm
(Caenorhabditis elegans) |
Secernentea |
nape-21 |
Protein NAPE-2 |
51.6(n)
44.58(a) |
|
177136 NM_171307.2 NP_741361.1 |
ENSEMBL Gene Tree for NAPEPLD (if available)
TreeFam Gene Tree for NAPEPLD (if available) |
Paralogs
for NAPEPLD gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for NAPEPLD gene
NAPEPLD for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for NAPEPLD
PGOHUM00000236354
|
Genomic Variants
for NAPEPLD gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for NAPEPLD (102740023 - 102790007 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 10 variations for NAPEPLD
9 CNVs: 94768 82127 94778 82131 36598 94772 9065 82134 82133
1 Indel: 94769 | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for NAPEPLD gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
NAPEPLD for disorders About GeneDecksing
OMIM gene information: 612334
OMIM disorders: --
5  diseases for NAPEPLD: About MalaCardsmultiple sclerosis obesity tuberculosis malaria
mycobacterium tuberculosis
Human Genome Epidemiology (HuGE) Navigator: NAPEPLD (1 document)
Export disorders for NAPEPLD gene to outside databases
|
Publications
for NAPEPLD gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for NAPEPLD gene, integrated from 9 sources (see all 16):
(articles sorted by number of sources associating them with NAPEPLD) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Isolation and analysis of candidate myeloid tumor suppressor genes from a commonly deleted segment of 7q22. (PubMed id 15820312)1, 2, 3 Curtiss N.P.... Shannon K.M. (2005)
- Molecular characterization of a phospholipase D generating anandamide and its congeners. (PubMed id 14634025)1, 2, 3 Okamoto Y.... Ueda N. (2004)
- Localization of N-acyl phosphatidylethanolamine phospholipase D (NAPE-PLD) expression in mouse brain: A new perspective on N-acylethanolamines as neural signaling molecules. (PubMed id 18067139)1, 3 Egertova M....Elphick M.R. (2008)
- Cannabinoid receptor and N-acyl phosphatidylethanolam ine phospholipase D--evidence for altered expression in multiple sclerosis. (PubMed id 21251115)1 Zhang H....Zajicek J. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- A Common Haplotype in NAPEPLD Is Associated With Seve re Obesity in a Norwegian Population-Based Cohort (the HUNT Study). (PubMed id 20885390)1 Wangensteen T....l L. (2010)
- Histomorphometric evaluation of cannabinoid receptor and anandamide modulating enzyme expression in the human endometrium through th e menstrual cycle. (PubMed id 20369362)1 Taylor A.H....Konje J.C. (2010)
- Effect of synthetic and natural phospholipids on N-ac ylphosphatidylethanolamine-hydrolyzing phospholipase D activity. (PubMed id 19715685)1 Petersen G....Hansen H.S. (2009)
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
|
External Searches for NAPEPLD gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing NAPEPLD gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing NAPEPLD gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NAPEPLD gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for NAPEPLD | Pharmacogenomics, SNPs, Pathways | | Wikipedia | http://en.wikipedia.org/wiki/N-acyl_phosphatidylethanolamine-specific_phospholipase_D |
|
| | |
About This Section
| Patent Information for NAPEPLD gene:
Search GeneIP for patents involving NAPEPLD
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for NAPEPLD gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
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| | |  | OriGene Antibodies for NAPEPLD | | OriGene shRNA RFP for NAPEPLD | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NAPEPLD | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NAPEPLD | | | OriGene Protein Over-expression Lysate for NAPEPLD | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for NAPEPLD | | OriGene 3'-UTR Clone for NAPEPLD | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NAPEPLD | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NAPEPLD | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for NAPEPLD | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for NAPEPLD | | OriGene Custom Protein Services for NAPEPLD | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NAPEPLD | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NAPEPLD | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NAPEPLD | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NAPEPLD | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NAPEPLD | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NAPEPLD |
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| | | | Search Tocris compounds for NAPEPLD |
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 | | | NAPEPLD Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NAPEPLD |
|  |  |  |  | | | | Search ThermoFisher Antibodies for NAPEPLD |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NAPEPLD |
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