Aliases for NAPB Gene
External Ids for NAPB Gene
Previous GeneCards Identifiers for NAPB Gene
This gene encodes a member of the soluble N-ethyl-maleimide-sensitive fusion attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. This gene encodes the SNAP beta isoform which has been shown to be preferentially expressed in brain tissue. The encoded protein also interacts with the GluR2 α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptor subunit C-terminus and may play a role as a chaperone in the molecular processing of the AMPA receptor. [provided by RefSeq, Mar 2017]
GeneCards Summary for NAPB Gene
NAPB (NSF Attachment Protein Beta) is a Protein Coding gene. Diseases associated with NAPB include Neurodegeneration With Brain Iron Accumulation 6. Among its related pathways are Intra-Golgi traffic and Vesicle-mediated transport. GO annotations related to this gene include syntaxin binding and soluble NSF attachment protein activity. An important paralog of this gene is NAPA.
UniProtKB/Swiss-Prot for NAPB Gene
Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.