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Aliases & Descriptions for NAPB
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| Aliases |
|---|
| MGC26066 2 | | MGC48335 2 | | MSF 5 | | MSF1 5 | | OTTHUMP00000030424 2 | | SEPT9 5 | | SNAP-BETA 1, 2 | | SNAP-beta 3 | | SNAPB 1, 2, 3 |
| | | Descriptions |
|---|
| N-ethylmaleimide-sensitive factor attachment protein beta 3 | | N-ethylmaleimide-sensitive factor attachment protein, beta 2 | | beta-soluble NSF attachment protein 2 |
|
| | Search outside databases for aliases for NAPB genePrevious GC identifers: GC17U990129 GC20M023350 |
Summaries for NAPB(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: SNAB_HUMAN, Q9H115Function: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (By similarity)Gene Wiki entry for NAPB |
Genomic Location for NAPB
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences) About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Transcription factor binding sites upstream to the NAPB gene 
Entrez Gene cytogenetic band: 20p12.3-p11.21 Ensembl cytogenetic band: 20p11.21 HGNC cytogenetic band: 20p12.3-p11.21NAPB Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)
 GeneLoc gene densities for chromosome 20 GeneLoc Exon Structure GeneLoc location for GC20M023303:
(about GC identifiers)
Start:
|
23,303,165 bp from pter |
End:
|
23,350,081 bp from pter |
Size:
|
46,917 bases |
Orientation:
|
minus strand |
RefSeq DNA sequence:- NC_000020.9 NT_011387.8
| Proteins for NAPB
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: SNAB_HUMAN, Q9H115 (See
protein sequence)Recommended Name: Beta-soluble NSF attachment protein Size: 298 amino acids; 33557 Da
Subunit: Interacts with PRKCABP, and disrupts the interaction between GRIA2 and PRKCABP, leading to the internalization of GRIA2 (By similarity)
Subcellular location: Membrane; Peripheral membrane protein (By similarity)
Secondary accessions: Q4G187 Q5JXF9 Q8N3C4REFSEQ proteins: NP_071363.1
ENSEMBL proteins: ENSP00000366225 ENSP00000381459
Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 
3 Gene Ontology (GO) cellular component terms (links to tree view): About this table
Antibodies for NAPB: Assays for NAPB: | Protein
Domains/ Families for NAPB(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry Q9H115
ProtoNet protein and cluster: Q9H115 1 Blocks protein family: IPB000744 NSF attachment protein signature
UniProtKB/Swiss-Prot: SNAB_HUMAN, Q9H115Similarity: Belongs to the SNAP family | Gene Function for NAPB
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_022080
Applied Biosystems Silencer® siRNAs for NAPB
Sigma-Aldrich siRNA for NAPB  Sigma-Aldrich shRNA for NAPB  Explore Sigma-Aldrich super-pooled esiRNAs 
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_022080                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_022080                                  untagged cDNA clones in CMV expression vector (see all 2): NM_022080 
Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_022080
UniProtKB/Swiss-Prot: SNAB_HUMAN, Q9H115Function: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (By similarity)1 Gene Ontology (GO) molecular function term (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005488 | binding |
IEA | -- | About this table | Pathways & Interactions for NAPB
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
| 1 Sigma-Aldrich "Your Favorite Gene" Pathway for NAPB (Your Favorite Gene powered by Ingenuity) 
--2 Gene Ontology (GO) biological process terms (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006886 | intracellular protein transport |
IEA | -- | | GO:0016192 | vesicle-mediated transport |
IEA | -- | About this table
|
Drugs & Compounds for NAPB(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
Browse Tocris compounds for NAPB
|
Transcripts for NAPB(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene, Expression Assays from Applied Biosystems) About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_022080
Sigma-Aldrich siRNA for NAPB  Sigma-Aldrich shRNA for NAPB  Explore Sigma-Aldrich super-pooled esiRNAs 
Applied Biosystems Silencer® siRNAs: NM_022080 REFSEQ mRNAs for NAPB gene: NM_022080.2
Applied Biosystems TaqMan ® Gene Expression Assays: NM_022080               OriGene GFP tagged cDNA clone in CMV expression vector: NM_022080                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_022080                                  untagged cDNA clones in CMV expression vector (see all 2): NM_022080  Additional cDNA sequence: AK022817.1 AK124876.1 AK294703.1 AK295791.1 AK296385.1 AK307709.1 AL834445.1 BC008463.1 BC026310.1 BC047426.1 BC060840.1 BX648330.1 15 DOTS entries: DT.449099 DT.101983121 DT.101983122 DT.99946862 DT.101983124 DT.100031457 DT.100781796 DT.97786086 DT.120839147 DT.120839159 DT.97842873 DT.120839158 DT.120839173 DT.120839174 DT.120839182 24/203 AceView cDNA sequences (see all 203
):BE327058 AI278427 AK124876 BM717893 BM128314 AK125811 CB069717 BU184334 BM699534 BM704222 AA351671 AA953489 AL834445 H91664 CK819291 CB127322 AW207670 BM930893 AI692909 BQ694031 F13158 F09971 T33462 AI305251
highest scoring ESTs for NAPB:AA083398 AI915331 AL713203 AW207670 AW207721 BG704245 BG704312 BI458311 BI544957 BI545009 Unigene Cluster for NAPB: N-ethylmaleimide-sensitive factor attachment protein, beta Hs.269471 [show with all ESTs]Unigene Representative Sequence: NM_022080
GeneLoc Exon Structure
5/16 Alternative Splicing Database (ASD) splice patterns (SP) for NAPB (see all 16
)
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2a | · | 2b | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | ^ | 9a | · | 9b | · | 9c | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13a | · | |
| SP1: | |   | |   | |   | |   | |   | |   | - |   | |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | - |   | |   | |   | - |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | - |   | |   | |   | - |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | - |   | |   | |   | - |   | |   | |   | - |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | - |   | |   | |   | - |   | |   | |   | - |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | - |   | |   | |   | - |   | |   |
| ExUns: | 13b | · | 13c | · | 13d | |
| SP1: | |   | |   | |   | |
| SP2: | |   | |   | |   | |
| SP3: | |   | |   | |   | |
| SP4: | |   | |   | |   | |
| SP5: | |   | |   | |   |
About this scheme
ECgene alternative splicing isoforms for NAPB
2 Ensembl transcripts including schematic representations: ENST00000377026
ENST00000398425
|
Expression for NAPB
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| NAPB expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for NAPB
1 / 2 / 3 4 probe-sets matching NAPB gene Data from
(Publications) and GNF BioGPS About these images About these images
CGAP SAGE TAG: TGTAACAATA
SOURCE GeneReport for Unigene cluster: Hs.269471
|
Orthologs for NAPB
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for NAPB gene from 5/12 species (see all 12
)
About this table Species with no ortholog for NAPB
ENSEMBL Gene Tree for NAPB | Paralogs for NAPB(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| Paralogs for NAPB gene
- NAPA2
|
SNPs/Variants for NAPB(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for NAPB (up to first 250kb)
|
Disorders & Mutations for NAPB
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 604061 |
Medical News for NAPB(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications for NAPB (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 9 PubMed articles for NAPB gene: |
Search for NAPB
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing NAPB
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing NAPB
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NAPB(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| About This Section
| --
| Services for NAPB(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals, Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience) About This Section
| 
 Products for NAPB:

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| | | | Search Tocris compounds for NAPB |
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GeneCards Homepage - Last full update: 1 Jul 2009
Incremental update: 13 Oct 2009
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