Aliases for NAPA Gene
External Ids for NAPA Gene
Previous GeneCards Identifiers for NAPA Gene
This gene encodes a member of the soluble NSF attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. The encoded protein plays a role in the completion of membrane fusion by mediating the interaction of N-ethylmaleimide-sensitive factor (NSF) with the vesicle-associated and membrane-associated SNAP receptor (SNARE) complex, and stimulating the ATPase activity of NSF. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jun 2011]
GeneCards Summary for NAPA Gene
NAPA (NSF Attachment Protein Alpha) is a Protein Coding gene. Among its related pathways are Golgi-to-ER retrograde transport and Retrograde transport at the Trans-Golgi-Network. GO annotations related to this gene include syntaxin binding and soluble NSF attachment protein activity. An important paralog of this gene is NAPB.
UniProtKB/Swiss-Prot for NAPA Gene
Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (Probable). Together with GNA12 promotes CDH5 localization to plasma membrane (PubMed:15980433).