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Aliases for NAP1L6 Gene

Aliases for NAP1L6 Gene

  • Nucleosome Assembly Protein 1 Like 6 2 3 5
  • Nucleosome Assembly Protein 1-Like 6 2

External Ids for NAP1L6 Gene

Previous GeneCards Identifiers for NAP1L6 Gene

  • GC0XM072262
  • GC0XM072345
  • GC0XM065979

Summaries for NAP1L6 Gene

GeneCards Summary for NAP1L6 Gene

NAP1L6 (Nucleosome Assembly Protein 1 Like 6) is a Pseudogene.

Additional gene information for NAP1L6 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NAP1L6 Gene

Genomics for NAP1L6 Gene

Regulatory Elements for NAP1L6 Gene

Enhancers for NAP1L6 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XH073576 0.6 ENCODE 4.1 -449.4 -449375 1 RFX1 JUN CEBPB BMI1 EP300 RFX5 JUND MAFK TCF7L2 CHIC1 FAM226B NAP1L6 PIR39676
GH0XH073128 0.5 ENCODE 0.7 -0.1 -97 0 PKNOX1 RFX1 POLR2A DDX20 CREB1 ERCC6L JPX NAP1L6 PIR55030
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around NAP1L6 on UCSC Golden Path with GeneCards custom track

Genomic Location for NAP1L6 Gene

Chromosome:
X
Start:
73,126,037 bp from pter
End:
73,128,080 bp from pter
Size:
2,044 bases
Orientation:
Minus strand

Genomic View for NAP1L6 Gene

Genes around NAP1L6 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NAP1L6 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NAP1L6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NAP1L6 Gene

Proteins for NAP1L6 Gene

  • Protein details for NAP1L6 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NFF2-NP1L6_HUMAN
    Recommended name:
    Putative nucleosome assembly protein 1-like 6
    Protein Accession:
    A6NFF2

    Protein attributes for NAP1L6 Gene

    Size:
    107 amino acids
    Molecular mass:
    12045 Da
    Quaternary structure:
    No Data Available

neXtProt entry for NAP1L6 Gene

Post-translational modifications for NAP1L6 Gene

No Post-translational modifications

No data available for DME Specific Peptides for NAP1L6 Gene

Domains & Families for NAP1L6 Gene

Gene Families for NAP1L6 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for NAP1L6 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for NAP1L6 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6NFF2

UniProtKB/Swiss-Prot:

NP1L6_HUMAN :
  • Belongs to the nucleosome assembly protein (NAP) family.
Family:
  • Belongs to the nucleosome assembly protein (NAP) family.
genes like me logo Genes that share domains with NAP1L6: view

Function for NAP1L6 Gene

Phenotypes for NAP1L6 Gene

GenomeRNAi human phenotypes for NAP1L6:
genes like me logo Genes that share phenotypes with NAP1L6: view

Animal Model Products

CRISPR Products

miRNA for NAP1L6 Gene

miRTarBase miRNAs that target NAP1L6

Clone Products

  • Applied Biological Materials Clones for NAP1L6
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for NAP1L6 Gene

Localization for NAP1L6 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for NAP1L6 gene
Compartment Confidence
nucleus 3
cytosol 2
mitochondrion 1

Gene Ontology (GO) - Cellular Components for NAP1L6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with NAP1L6: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for NAP1L6 Gene

Pathways & Interactions for NAP1L6 Gene

SuperPathways for NAP1L6 Gene

No Data Available

Interacting Proteins for NAP1L6 Gene

Gene Ontology (GO) - Biological Process for NAP1L6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006334 nucleosome assembly IEA --
genes like me logo Genes that share ontologies with NAP1L6: view

No data available for Pathways by source and SIGNOR curated interactions for NAP1L6 Gene

Drugs & Compounds for NAP1L6 Gene

No Compound Related Data Available

Transcripts for NAP1L6 Gene

mRNA/cDNA for NAP1L6 Gene

(2) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for NAP1L6 Gene

Nucleosome assembly protein 1-like 6:
Representative Sequences:

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for NAP1L6
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for NAP1L6 Gene

No ASD Table

Relevant External Links for NAP1L6 Gene

GeneLoc Exon Structure for
NAP1L6
ECgene alternative splicing isoforms for
NAP1L6

Expression for NAP1L6 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for NAP1L6 Gene

mRNA differential expression in normal tissues according to GTEx for NAP1L6 Gene

This gene is overexpressed in Brain - Spinal cord (cervical c-1) (x7.8).

NURSA nuclear receptor signaling pathways regulating expression of NAP1L6 Gene:

NAP1L6

SOURCE GeneReport for Unigene cluster for NAP1L6 Gene:

Hs.617486

Evidence on tissue expression from TISSUES for NAP1L6 Gene

  • Nervous system(4.2)
  • Eye(2.4)
genes like me logo Genes that share expression patterns with NAP1L6: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for NAP1L6 Gene

Orthologs for NAP1L6 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for NAP1L6 Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
Mammalia Gm4204 34
  • 13 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 12 (a)
ManyToMany
-- 34
  • 11 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 11 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 34
  • 9 (a)
ManyToMany
-- 34
  • 9 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia NAP1L6 34
OneToOne
chicken
(Gallus gallus)
Aves -- 34
  • 11 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 11 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii nap1l1 34
  • 11 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta Nap1 34
  • 6 (a)
ManyToMany
CG5017 34
  • 6 (a)
ManyToMany
CG3708 34
  • 5 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea nap-1 34
  • 9 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes NAP1 34
  • 5 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.925 34
  • 9 (a)
OneToMany
Species where no ortholog for NAP1L6 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for NAP1L6 Gene

ENSEMBL:
Gene Tree for NAP1L6 (if available)
TreeFam:
Gene Tree for NAP1L6 (if available)

Paralogs for NAP1L6 Gene

(4) SIMAP similar genes for NAP1L6 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with NAP1L6: view

No data available for Paralogs for NAP1L6 Gene

Variants for NAP1L6 Gene

Sequence variations from dbSNP and Humsavar for NAP1L6 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs1000252755 -- 73,127,104(+) TGGGC(A/C)GCTGG nc-transcript-variant
rs1000631680 -- 73,128,401(+) TTATA(A/T)TTAAA upstream-variant-2KB
rs1000982386 -- 73,129,118(+) TGTGT(G/T)TGTGT upstream-variant-2KB
rs1001523143 -- 73,127,836(+) GTAAT(A/G)GGCCC nc-transcript-variant
rs1001700010 -- 73,127,457(+) ACGAT(C/G)CTCCA nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for NAP1L6 Gene

Variant ID Type Subtype PubMed ID
esv3574047 CNV loss 25503493

Variation tolerance for NAP1L6 Gene

Gene Damage Index Score: 0.41; 8.93% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for NAP1L6 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
NAP1L6

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NAP1L6 Gene

Disorders for NAP1L6 Gene

Relevant External Links for NAP1L6

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
NAP1L6

No disorders were found for NAP1L6 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NAP1L6 Gene

Publications for NAP1L6 Gene

  1. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross MT … Bentley DR (Nature 2005) 3 4 60
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  3. A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene. (PMID: 19490893) Luo J … Elledge SJ (Cell 2009) 3 60

Products for NAP1L6 Gene

Sources for NAP1L6 Gene

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