NAP1L5 Gene
protein-coding GIFtS : 47
GCID: GC04 M089617
nucleosome assembly protein 1-like 5
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Aliasesfor NAP1L5 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Nucleosome Assembly Protein 1-Like 5 1 2 DRLM1 2 3 5 Down-Regulated In Liver Malignancy2 3
Export aliases for NAP1L5 gene to outside databases Previous GC identifers: GC04M090075 GC04M089974 GC04M089836 GC04M085368
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Summariesfor NAP1L5 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
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Genomic Viewsfor NAP1L5 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000004.11 NC_018915.1 NT_016354.19 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the NAP1L5 gene promoter: c-Fos TBP AP-1 JunB FosB Fra-1 Lmo2 POU2F1 POU2F1a c-Jun Other transcription factors Search SABiosciences Chromatin IP Primers for NAP1L5 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NAP1L5
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 4q22.1|4q21-q22 Ensembl cytogenetic band: 4q22.1 HGNC cytogenetic band: 4q21-q22 NAP1L5 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 4 GeneLoc Exon Structure
GeneLoc location for GC04M089617: view genomic region
(about GC identifiers )
Start:
89,617,066 bp from pter
End:
89,619,386 bp from pter
Size:
2,321 bases
Orientation:
minus strand
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Proteinsfor NAP1L5 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: NP1L5_HUMAN, Q96NT1 (See
protein sequence )Recommended Name: Nucleosome assembly protein 1-like 5 Size : 182 amino acids; 19593 Da
Subcellular location : Nucleus (Potential)Explore the universe of human proteins at neXtProt for NAP1L5: NX_Q96NT1 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q96NT1 NAP1L5 Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins: NP_715638.1 ENSEMBL proteins: ENSP00000320488 Human Recombinant Protein Products: Gene Ontology (GO): 1 cellular component term (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0005634 nucleus
IEA --
NAP1L5 for ontologies About GeneDecksing NAP1L5 Antibody Products: Assay Products for NAP1L5:
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Protein
Domains / Familiesfor NAP1L5 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
NAP1L5 for domains About GeneDecksing 1 InterPro domain/family :
Graphical View of Domain Structure for InterPro Entry Q96NT1 ProtoNet protein and cluster: Q96NT1
UniProtKB/Swiss-Prot: NP1L5_HUMAN, Q96NT1 Similarity : Belongs to the nucleosome assembly protein (NAP) family
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Functionfor NAP1L5 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for NAP1L5 (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for NAP1L5OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: NAP1L5 (NM_153757 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NAP1L5 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat NAP1L5
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NAP1L5
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Pathways & Interactionsfor NAP1L5 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NAP1L5 STRING Interaction
Network Preview (showing 5 interactants - click image to see more details)5/11 Interacting proteins for NAP1L5 (Q96NT1 2 , 3 ENSP00000320488 4 ) via UniProtKB, MINT, STRING , and/or I2D (see all 11 )About this table Gene Ontology (GO): 1 biological process term (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0006334 nucleosome assembly
IEA --
NAP1L5 for ontologies About GeneDecksing
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Drugs & Compoundsfor NAP1L5 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for NAP1L5 Search CenterWatch for drugs/clinical trials and news about NAP1L5 / NP1L5
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Transcriptsfor NAP1L5 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for NAP1L5 gene: NM_153757.2 Unigene Cluster for NAP1L5:
Nucleosome assembly protein 1-like 5 Hs.12554 [show with all ESTs ] Unigene Representative Sequence: NM_153757 1 Ensembl transcript including schematic representation, and UCSC links where relevant : ENST00000323061 (uc003hrx.3 ) Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for NAP1L5 (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for NAP1L5OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: NAP1L5 (NM_153757 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NAP1L5 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat NAP1L5
Additional cDNA sequence: AK054689.1 AL834329.1 BC022544.1 BC039416.1 BC104883.1
5 DOTS entries : DT.214207 DT.428686
DT.100774043 DT.121250597 DT.100722910 24/88 AceView cDNA sequences (see all 88 ):
BQ771809 AI090144 CB047189 F10839 AA954245 AI816344 Z38846 AI431867 AA838733 Z42684 BQ010322 N21977 AI040731 AI246169 AI816263 CR591413 AA772367 AW161560 AI364276 CA393605 CK300824 AI744533 BE503105 BX452219 GeneLoc Exon Structure
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Expression for NAP1L5 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section NAP1L5 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: TAGCTTTTAG
About this image NAP1L5 expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table See NAP1L5 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for NAP1L5 SOURCE GeneReport for Unigene cluster: Hs.12554 UniProtKB/Swiss-Prot: NP1L5_HUMAN, Q96NT1 Tissue specificity : Predominantly expressed in brain SABiosciences Custom PCR Arrays for NAP1L5 Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for NAP1L5Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat NAP1L5 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat NAP1L5 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat NAP1L5 In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NAP1L5
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Orthologsfor NAP1L5 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of eukaryotes.
Orthologs for NAP1L5 gene from 5/21 species (see all 21 ) About this table
ENSEMBL Gene Tree for NAP1L5 (if available)TreeFam Gene Tree for NAP1L5 (if available)
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Paralogsfor NAP1L5 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for NAP1L5 gene NAP1L3 2 NAP1L6 2 NAP1L2 2 NAP1L4 2 NAP1L1 2 5 SIMAP similar genes for NAP1L5 using alignment to 1 protein entry: NP1L5_HUMAN :DKFZp434K0835 NAP1L4 NAP1L4b NAP1L3 NAP1L2
NAP1L5 for paralogs About GeneDecksing 1 Pseudogenes.org Pseudogene for NAP1L5 PGOHUM00000238271
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Genomic Variantsfor NAP1L5 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing NAP1L5
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Disorders
/ Diseasesfor NAP1L5 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
NAP1L5 for disorders About GeneDecksing
OMIM gene information: 612203
OMIM disorders : --2 diseases for NAP1L5 : About MalaCards obesity malaria Human Genome Epidemiology (HuGE) Navigator: NAP1L5 (1 document)Export disorders for NAP1L5 gene to outside databases
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Publicationsfor NAP1L5 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for NAP1L5 gene, integrated from 9 sources (see all 13 ): (articles sorted by number of sources associating them with NAP1L5) Utopia : connect your pdf to the dynamic world of online information
Down-regulation of a novel gene, DRLM, in human liver malignancy from 4q22 that encodes a NAP-like protein. (PubMed id 12383514) 1 , 2 , 3 Harada H....Emi M. (2002) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 Ota T.... Sugano S. (2004) A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883) 1 Kristensen A.R....Foster L.J. (2012) A human MAP kinase interactome. (PubMed id 20936779) 1 Bandyopadhyay S....Ideker T. (2010) Large copy-number variations are enriched in cases wi th moderate to extreme obesity. (PubMed id 20622171) 1 Wang K....Price R.A. (2010) Expanding the substantial interactome of NEMO using p rotein microarrays. (PubMed id 20098747) 1 Fenner B.J....Prehn J.H. (2010) A screen for retrotransposed imprinted genes reveals an association between X chromosome homology and maternal germ-line methylation. (PubMed id 17291163) 1 Wood A.J....Oakey R.J. (2007) Large-scale mapping of human protein-protein interactions by mass spectrometry. (PubMed id 17353931) 1 Ewing R.M.... Figeys D. (2007) Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560) 1 Kimura K.... Sugano S. (2006) A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070) 1 Stelzl U.... Wanker E.E. (2005)
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External Searches for NAP1L5 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing NAP1L5 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing NAP1L5 gene
(According to HUGE )
About This Section --
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Specialized Databases showing NAP1L5 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
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About This Section Patent Information for NAP1L5 gene: Search GeneIP for patents involving NAP1L5 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor NAP1L5 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
Browse OriGene Antibodies OriGene shRNA RFP for NAP1L5 OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for NAP1L5 OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for NAP1L5 OriGene Protein Over-expression Lysate for NAP1L5 Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for NAP1L5 OriGene 3'-UTR Clone for NAP1L5 OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for NAP1L5 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for NAP1L5 Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for NAP1L5 OriGene Custom Protein Services for NAP1L5 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NAP1L5 QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing NAP1L5 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NAP1L5 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat NAP1L5 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat NAP1L5 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat NAP1L5
Search Tocris compounds for NAP1L5
NAP1L5 Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NAP1L5
ThermoFisher Antibodies for NAP1L5
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat NAP1L5
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Databases for NAP1L5
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Drugs / Compounds for NAP1L5
Expression for NAP1L5
Function for NAP1L5
Genomic Views for NAP1L5
Intellectual Property for NAP1L5
Orthologs for NAP1L5
Paralogs for NAP1L5
Pathways / Interactions for NAP1L5
Products for NAP1L5
Proteins for NAP1L5
Publications for NAP1L5
Search Box for NAP1L5
Summaries for NAP1L5
Transcripts for NAP1L5
Variants for NAP1L5
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