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Aliases for NAP1L5 Gene

Aliases for NAP1L5 Gene

  • Nucleosome Assembly Protein 1-Like 5 2 3
  • DRLM 3 4 6
  • Down-Regulated In Liver Malignancy 3 4

External Ids for NAP1L5 Gene

Previous GeneCards Identifiers for NAP1L5 Gene

  • GC04M090075
  • GC04M089974
  • GC04M089836
  • GC04M089617
  • GC04M085368

Summaries for NAP1L5 Gene

GeneCards Summary for NAP1L5 Gene

NAP1L5 (Nucleosome Assembly Protein 1-Like 5) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NAP1L5 Gene

Genomics for NAP1L5 Gene

Regulatory Elements for NAP1L5 Gene

Genomic Location for NAP1L5 Gene

Start:
88,695,915 bp from pter
End:
88,698,235 bp from pter
Size:
2,321 bases
Orientation:
Minus strand

Genomic View for NAP1L5 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for NAP1L5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NAP1L5 Gene

Proteins for NAP1L5 Gene

  • Protein details for NAP1L5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96NT1-NP1L5_HUMAN
    Recommended name:
    Nucleosome assembly protein 1-like 5
    Protein Accession:
    Q96NT1
    Secondary Accessions:

    Protein attributes for NAP1L5 Gene

    Size:
    182 amino acids
    Molecular mass:
    19593 Da
    Quaternary structure:
    No Data Available

neXtProt entry for NAP1L5 Gene

Proteomics data for NAP1L5 Gene at MOPED

Post-translational modifications for NAP1L5 Gene

  • Ubiquitination at Lys78
  • Modification sites at PhosphoSitePlus

Other Protein References for NAP1L5 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for NAP1L5 Gene

Domains for NAP1L5 Gene

Protein Domains for NAP1L5 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for NAP1L5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96NT1

UniProtKB/Swiss-Prot:

NP1L5_HUMAN :
  • Q96NT1
Family:
  • Belongs to the nucleosome assembly protein (NAP) family.
genes like me logo Genes that share domains with NAP1L5: view

No data available for Gene Families for NAP1L5 Gene

Function for NAP1L5 Gene

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for NAP1L5

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for NAP1L5 Gene

Localization for NAP1L5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for NAP1L5 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for NAP1L5 Gene COMPARTMENTS Subcellular localization image for NAP1L5 gene
Compartment Confidence
cytosol 3
nucleus 3
extracellular 1

Gene Ontology (GO) - Cellular Components for NAP1L5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with NAP1L5: view

Pathways for NAP1L5 Gene

SuperPathways for NAP1L5 Gene

No Data Available

Gene Ontology (GO) - Biological Process for NAP1L5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006334 nucleosome assembly IEA --
genes like me logo Genes that share ontologies with NAP1L5: view

No data available for Pathways by source for NAP1L5 Gene

Transcripts for NAP1L5 Gene

mRNA/cDNA for NAP1L5 Gene

(88) Selected AceView cDNA sequences:
(5) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for NAP1L5 Gene

Nucleosome assembly protein 1-like 5:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for NAP1L5

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for NAP1L5 Gene

No ASD Table

Relevant External Links for NAP1L5 Gene

GeneLoc Exon Structure for
NAP1L5
ECgene alternative splicing isoforms for
NAP1L5

Expression for NAP1L5 Gene

mRNA expression in normal human tissues for NAP1L5 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for NAP1L5 Gene

This gene is overexpressed in Brain - Hypothalamus (6.3), Brain - Frontal Cortex (BA9) (5.6), and Brain - Anterior cingulate cortex (BA24) (5.6).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for NAP1L5 Gene

SOURCE GeneReport for Unigene cluster for NAP1L5 Gene Hs.12554

mRNA Expression by UniProt/SwissProt for NAP1L5 Gene

Q96NT1-NP1L5_HUMAN
Tissue specificity: Predominantly expressed in brain.
genes like me logo Genes that share expressions with NAP1L5: view

In Situ Assay Products

Orthologs for NAP1L5 Gene

This gene was present in the common ancestor of mammals.

Orthologs for NAP1L5 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia NAP1L5 35
  • 98.35 (n)
  • 96.15 (a)
NAP1L5 36
  • 96 (a)
OneToOne
cow
(Bos Taurus)
Mammalia NAP1L5 35
  • 89.05 (n)
  • 91.04 (a)
NAP1L5 36
  • 77 (a)
OneToOne
dog
(Canis familiaris)
Mammalia NAP1L5 35
  • 89.52 (n)
  • 91.13 (a)
NAP1L5 36
  • 84 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Nap1l5 35
  • 79.34 (n)
  • 84.3 (a)
Nap1l5 16
Nap1l5 36
  • 78 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Nap1l5 35
  • 78.79 (n)
  • 84.3 (a)
Species with no ortholog for NAP1L5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for NAP1L5 Gene

ENSEMBL:
Gene Tree for NAP1L5 (if available)
TreeFam:
Gene Tree for NAP1L5 (if available)

Paralogs for NAP1L5 Gene

Selected SIMAP similar genes for NAP1L5 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for NAP1L5 Gene

genes like me logo Genes that share paralogs with NAP1L5: view

No data available for Paralogs for NAP1L5 Gene

Variants for NAP1L5 Gene

Sequence variations from dbSNP and Humsavar for NAP1L5 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type MAF
VAR_050227 -

Structural Variations from Database of Genomic Variants (DGV) for NAP1L5 Gene

Variant ID Type Subtype PubMed ID
nsv461576 CNV Gain 19166990

Relevant External Links for NAP1L5 Gene

HapMap Linkage Disequilibrium report
NAP1L5

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NAP1L5 Gene

Disorders for NAP1L5 Gene

Relevant External Links for NAP1L5

Genetic Association Database (GAD)
NAP1L5
Human Genome Epidemiology (HuGE) Navigator
NAP1L5
genes like me logo Genes that share disorders with NAP1L5: view

No data available for UniProtKB/Swiss-Prot for NAP1L5 Gene

Publications for NAP1L5 Gene

  1. Down-regulation of a novel gene, DRLM, in human liver malignancy from 4q22 that encodes a NAP-like protein. (PMID: 12383514) Harada H. … Emi M. (Gene 2002) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Large copy-number variations are enriched in cases with moderate to extreme obesity. (PMID: 20622171) Wang K. … Price R.A. (Diabetes 2010) 3 48
  4. A human MAP kinase interactome. (PMID: 20936779) Bandyopadhyay S. … Ideker T. (Nat. Methods 2010) 3
  5. A high-throughput approach for measuring temporal changes in the interactome. (PMID: 22863883) Kristensen A.R. … Foster L.J. (Nat. Methods 2012) 3

Products for NAP1L5 Gene

Sources for NAP1L5 Gene

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