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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NAP1L4 Gene

protein-coding   GIFtS: 55
GCID: GC11M002965

Nucleosome Assembly Protein 1-Like 4

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Nucleosome Assembly Protein 1-Like 41 2     NAP2L2 5
NAP22 3 5     NAP1L4b2
Nucleosome Assembly Protein 22 3     hNAP22
NAP-22 3     Nucleosome Assembly Protein 1-Like 4b2

External Ids:    HGNC: 76401   Entrez Gene: 46762   Ensembl: ENSG000002055317   OMIM: 6016515   UniProtKB: Q997333   

Export aliases for NAP1L4 gene to outside databases

Previous GC identifers: GC11M003025 GC11M003216 GC11M002924 GC11M002929 GC11M002919 GC11M002922 GC11M002754


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NAP1L4 Gene:
This gene encodes a member of the nucleosome assembly protein (NAP) family which can interact with both core and
linker histones. It can shuttle between the cytoplasm and nucleus, suggesting a role as a histone chaperone. This
gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene
region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor,
rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. (provided by RefSeq, Jul 2008)

GeneCards Summary for NAP1L4 Gene: 
NAP1L4 (nucleosome assembly protein 1-like 4) is a protein-coding gene. Diseases associated with NAP1L4 include beckwith-wiedemann syndrome, and wilms tumor. GO annotations related to this gene include unfolded protein binding and protein binding. An important paralog of this gene is NAP1L3.

Gene Wiki entry for NAP1L4 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NT_009237.18  NC_018922.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NAP1L4 gene promoter:
         NF-YA   CBF-C   C/EBPalpha   CHOP-10   CBF-A   CBF-B   CP1A   CP1C   NF-Y   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNAP1L4 promoter sequence
   Search SABiosciences Chromatin IP Primers for NAP1L4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NAP1L4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p15.5   Ensembl cytogenetic band:  11p15.4   HGNC cytogenetic band: 11p15.5

NAP1L4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NAP1L4 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M002965:  view genomic region     (about GC identifiers)

Start:
2,965,660 bp from pter      End:
3,013,607 bp from pter
Size:
47,948 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NP1L4_HUMAN, Q99733 (See protein sequence)
Recommended Name: Nucleosome assembly protein 1-like 4  
Size: 375 amino acids; 42823 Da
Subcellular location: Nucleus

Explore the universe of human proteins at neXtProt for NAP1L4: NX_Q99733

Explore proteomics data for NAP1L4 at MOPED 

Post-translational modifications:

  • UniProtKB: Polyglutamylated by TTLL4, a modification that occurs exclusively on glutamate residues and results in
    polyglutamate chains on the gamma-carboxyl group. Some residues may also be monoglycylated but not polyglycylated
    due to the absence of functional TTLL10 in human (By similarity)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q99733

  • NAP1L4 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NAP1L4 Protein Expression
    REFSEQ proteins: NP_005960.1  
    ENSEMBL proteins: 
     ENSP00000369915   ENSP00000436397   ENSP00000431644   ENSP00000436488   ENSP00000387783  
     ENSP00000382523   ENSP00000405912   ENSP00000435327   ENSP00000434759   ENSP00000432126  
     ENSP00000431799   ENSP00000437130   ENSP00000412048   ENSP00000433512  

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    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for NAP1L4 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm TAS9325046

    NAP1L4 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR002164 NAP_family

    Graphical View of Domain Structure for InterPro Entry Q99733

    ProtoNet protein and cluster: Q99733

    1 Blocks protein domain: IPB002164 Nucleosome assembly protein (NAP)

    UniProtKB/Swiss-Prot: NP1L4_HUMAN, Q99733
    Similarity: Belongs to the nucleosome assembly protein (NAP) family


    NAP1L4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:
         Genatlas biochemistry entry for NAP1L4:
    nucleosome assembly protein 1-like 4, excluded of the imprinting domain,interacting with core and linker
    histones,putative chaperone

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0051082unfolded protein binding TAS9325046
         
    NAP1L4 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for NAP1L4 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for NAP1L4

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NAP1L4 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NAP1L4 

    miRNA
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    hsa-miR-26a-2* hsa-miR-520d-5p hsa-miR-570 hsa-miR-633 hsa-miR-4325 hsa-miR-33b hsa-miR-3148 hsa-miR-203
    SwitchGear 3'UTR luciferase reporter plasmidNAP1L4 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NAP1L4

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/227 Interacting proteins for NAP1L4 (Q997331, 3 ENSP000003699154) via UniProtKB, MINT, STRING, and/or I2D (see all 227)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053, ENSP000003529804I2D: score=7 STRING: ENSP00000352980
    HIST2H4AP628053, ENSP000003581624I2D: score=7 STRING: ENSP00000358162
    HIST1H4BP628053I2D: score=7 
    HIST1H4CP628053I2D: score=7 
    HIST1H4DP628053I2D: score=7 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006334nucleosome assembly IEA--

    NAP1L4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    NAP1L4 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NAP1L4 (NP1L4)

    2 Novoseek inferred chemical compound relationships for NAP1L4 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    nap-2 94.3 3 9268640 (1), 9618174 (1)
    heparin 23 2 10764593 (1), 15368365 (1)

    Search CenterWatch for drugs/clinical trials and news about NAP1L4 / NP1L4

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NAP1L4 gene: 
    NM_005969.3  

    Unigene Cluster for NAP1L4:

    Nucleosome assembly protein 1-like 4
    Hs.731784  [show with all ESTs]
    Unigene Representative Sequence: NM_005969
    18/21 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 21):
    ENST00000380542(uc001lxc.3 uc010qxm.2 uc010qxn.2) ENST00000469805(uc001lxb.3)
    ENST00000469089 ENST00000526115 ENST00000492594 ENST00000526023 ENST00000492685
    ENST00000528363 ENST00000483643 ENST00000528261 ENST00000532325 ENST00000448187
    ENST00000399614 ENST00000430811 ENST00000529361 ENST00000528968 ENST00000530064
    ENST00000526842
    miRNA
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    8/19 QIAGEN miScript miRNA Assays for microRNAs that regulate NAP1L4 (see all 19):
    hsa-miR-26a-2* hsa-miR-520d-5p hsa-miR-570 hsa-miR-633 hsa-miR-4325 hsa-miR-33b hsa-miR-3148 hsa-miR-203
    SwitchGear 3'UTR luciferase reporter plasmidNAP1L4 3' UTR sequence
    Inhib. RNA
    Products:
         
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NAP1L4
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NAP1L4

    Additional mRNA sequence: 

    AB500094.1 AK299515.1 AK311098.1 AK312599.1 AK316242.1 AK316324.1 AK316548.1 BC022090.2 
    U77456.1 XR_158864.1 XR_159203.1 XR_171882.1 

    24/30 DOTS entries (see all 30):

    DT.448916  DT.95197346  DT.100798067  DT.92462968  DT.120697094  DT.97769343  DT.100811147  DT.92462973 
    DT.86854900  DT.439912  DT.120697081  DT.120697111  DT.101968316  DT.92063326  DT.95192027  DT.120697077 
    DT.40298417  DT.95197340  DT.100798070  DT.102842833  DT.120697088  DT.120697115  DT.120697146  DT.120697152 

    24/569 AceView cDNA sequences (see all 569):

    BM987913 H92201 AU131612 BM724553 BX644512 AW250177 BG253418 AI950804 
    AK095320 BE385383 AI290669 AW246975 BM458422 BX394357 BQ014770 CR624939 
    BQ219178 H96204 BQ008969 H92347 AA243551 AW274745 BM834137 BQ051319 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NAP1L4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACGCAGGCGC
    NAP1L4 Expression
    About this image


    See NAP1L4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NAP1L4

    SOURCE GeneReport for Unigene cluster: Hs.731784

    UniProtKB/Swiss-Prot: NP1L4_HUMAN, Q99733
    Tissue specificity: Ubiquitous. Biallelically expressed in fetal and adult tissues. Highest levels in testis

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for NAP1L4 gene from 9/19 species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nap1l41 , 5 nucleosome assembly protein 1-like 41, 5 85.87(n)1
    94.67(a)1
      7 (88.24 cM)5
    179551  NM_008672.21  NP_032698.11 
     1435135795 
    chicken
    (Gallus gallus)
    Aves NAP1L41 nucleosome assembly protein 1-like 4 83.29(n)
    87.94(a)
      423087  NM_001006469.1  NP_001006469.1 
    lizard
    (Anolis carolinensis)
    Reptilia NAP1L46
    nucleosome assembly protein 1-like 4
    87(a)
    1 ↔ 1
    1(68646490-68699662)
    zebrafish
    (Danio rerio)
    Actinopterygii nap1l4b1 nucleosome assembly protein 1-like 4b 71.35(n)
    71.93(a)
      492812  NM_001007453.1  NP_001007454.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Nap13 nucleosome assembly histone-specific
    chaperone
    51(a)
    (best of 2)
      60A9   --
    worm
    (Caenorhabditis elegans)
    Secernentea D2096.83   -- 37(a)   IV(8378271-8379497)   --
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes NAP1(YKR048C)4
    NAP11
    Protein that interacts with mitotic cyclin Clb2p; required more4
    Nap1p1
    47.19(n)1
    37.95(a)1
      11(526640-525387)4
    8539221, 4  NP_012974.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons NAP1;11 nucleosome assembly protein 1-like 1 54.69(n)
    44.37(a)
      828717  NM_118744.2  NP_194341.1 
    rice
    (Oryza sativa)
    Liliopsida Os06g01494001 hypothetical protein 54.46(n)
    44.55(a)
      4340137  NM_001063351.1  NP_001056816.1 


    ENSEMBL Gene Tree for NAP1L4 (if available)
    TreeFam Gene Tree for NAP1L4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NAP1L4 gene
    NAP1L32  NAP1L62  NAP1L22  NAP1L12  
    6 SIMAP similar genes for NAP1L4 using alignment to 14 protein entries:     NP1L4_HUMAN (see all proteins):
    NAP1L4b    NAP1L1    NAP1L6    NAP1L2    DKFZp434K0835    NAP1L5

    NAP1L4 for paralogs           About GeneDecksing


    3 Pseudogenes.org Pseudogenes for NAP1L4
    PGOHUM00000244155 PGOHUM00000241492 PGOHUM00000241522


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1088 SNPs in NAP1L4 are shown (see all 1088)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs587553331,2
    C--2796158(+) AGAAA-/AAGAAA
            
    GGAAA
    1 -- int11Minor allele frequency- AAGAAA:0.00NA 2
    rs740504421,2
    C,F--2965191(+) ACAGCG/ATTTCA 1 -- ds50012Minor allele frequency- A:0.08WA 120
    rs122861201,2
    C,F,A--2965252(+) GTGCCG/TGTGCA 1 -- ds500111Minor allele frequency- T:0.12NA WA CSA EA 371
    rs1845906091,2
    --2965275(+) TGCCTC/TCTCTC 1 -- ds50010--------
    rs1876493161,2
    --2965313(+) AGCTTC/TAGAGA 1 -- ds50010--------
    rs1438534251,2
    --2965422(+) CCTGGC/GGGCAG 1 -- ds50010--------
    rs1925593591,2
    --2965449(+) GGCCCC/GCAGTG 1 -- ds50010--------
    rs10505541,2
    --2965705(-) GTACAG/TAATAG 1 -- ut31 ese32Minor allele frequency- T:0.00NA 4
    rs106701,2
    C,F--2965728(+) CTGTAT/ATCAGT 1 -- ut31 ese34Minor allele frequency- A:0.03MN NA WA 306
    rs10505531,2
    --2965736(-) CATTTG/ATAACT 1 -- ut312Minor allele frequency- A:0.00NA 4

    HapMap Linkage Disequilibrium report for NAP1L4 (2965660 - 3013607 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for NAP1L4:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2744026CNV Deletion23290073
    nsv7648CNV Insertion18451855
    dgv1009n71CNV Loss21882294
    dgv1013n71CNV Loss21882294
    nsv832050CNV Loss17160897
    nsv8766CNV Loss18304495

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 601651    OMIM disorders: --

    7 diseases for NAP1L4:    About MalaCards
    beckwith-wiedemann syndrome    wilms tumor    adrenocortical carcinoma    rhabdomyosarcoma
    breast cancer    alcohol dependence    alcoholism

    1 disease from the University of Copenhagen DISEASES database for NAP1L4:
    Beckwith-Wiedemann syndrome

    NAP1L4 for disorders           About GeneDecksing

    3 Novoseek inferred disease relationships for NAP1L4 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    beckwith-wiedemann syndrome 88.2 1 10777363 (1)
    wilms tumor 67.6 1 9325046 (1)
    tumors 7.48 1 9325046 (1)

    Genetic Association Database (GAD): NAP1L4
    Human Genome Epidemiology (HuGE) Navigator: NAP1L4 (1 document)

    Export disorders for NAP1L4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NAP1L4 gene, integrated from 9 sources (see all 50):
    (articles sorted by number of sources associating them with NAP1L4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A novel human homologue of yeast nucleosome assembly protein, 65 kb centromeric to the p57KIP2 gene, is biallelically expressed in fetal and adult tissues. (PubMed id 8923002)1, 2, 3 Hu R.-J.... Feinberg A.P. (1996)
    2. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Functional characterization of human nucleosome assembly protein-2 (NAP1L4) suggests a role as a histone chaperone. (PubMed id 9325046)1, 9 Rodriguez P....Pelletier J. (1997)
    5. NAP-2: histone chaperone function and phosphorylation state through the cell cycle. (PubMed id 10764593)1, 9 Rodriguez P....Zannis-Hadjopoulos M. (2000)
    6. NAP-2 is part of multi-protein complexes in HeLa cells. (PubMed id 15368365)1, 9 Rodriguez P....Zannis-Hadjopoulos M. (2004)
    7. The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells. (PubMed id 23667531)1 Cox J.L....Rizzino A. (2013)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    9. Host cell interactome of HIV-1 Rev includes RNA helica ses involved in multiple facets of virus production. (PubMed id 22174317)1 Naji S....Gerace L. (2012)
    10. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
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      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 4676 HGNC: 7640 AceView: NAP1L4 Ensembl:ENSG00000205531 euGenes: HUgn4676
    ECgene: NAP1L4 H-InvDB: NAP1L4

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NAP1L4 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for NAP1L4 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NAP1L4 gene:
    Search GeneIP for patents involving NAP1L4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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