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Aliases for NAP1L3 Gene

Aliases for NAP1L3 Gene

  • Nucleosome Assembly Protein 1-Like 3 2 3
  • Npl3 3
  • MB20 3
  • BNAP 4

External Ids for NAP1L3 Gene

Summaries for NAP1L3 Gene

Entrez Gene Summary for NAP1L3 Gene

  • This gene is intronless and encodes a member of the nucleosome assembly protein (NAP) family. This gene is linked closely to a region of genes responsible for several X-linked mental retardation syndromes. [provided by RefSeq, Dec 2010]

GeneCards Summary for NAP1L3 Gene

NAP1L3 (Nucleosome Assembly Protein 1-Like 3) is a Protein Coding gene. An important paralog of this gene is NAP1L4.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NAP1L3 Gene

Genomics for NAP1L3 Gene

Genomic Location for NAP1L3 Gene

Start:
93,670,926 bp from pter
End:
93,673,683 bp from pter
Size:
2,758 bases
Orientation:
Minus strand

Genomic View for NAP1L3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for NAP1L3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NAP1L3 Gene

Regulatory Elements for NAP1L3 Gene

Proteins for NAP1L3 Gene

  • Protein details for NAP1L3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q99457-NP1L3_HUMAN
    Recommended name:
    Nucleosome assembly protein 1-like 3
    Protein Accession:
    Q99457
    Secondary Accessions:
    • B2RCM0
    • O60788

    Protein attributes for NAP1L3 Gene

    Size:
    506 amino acids
    Molecular mass:
    57593 Da
    Quaternary structure:
    No Data Available

neXtProt entry for NAP1L3 Gene

Proteomics data for NAP1L3 Gene at MOPED

Post-translational modifications for NAP1L3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for NAP1L3 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for NAP1L3 Gene

Domains for NAP1L3 Gene

Protein Domains for NAP1L3 Gene

Suggested Antigen Peptide Sequences for NAP1L3 Gene

Graphical View of Domain Structure for InterPro Entry

Q99457

UniProtKB/Swiss-Prot:

NP1L3_HUMAN
Family:
  • Belongs to the nucleosome assembly protein (NAP) family.:
    • Q99457
genes like me logo Genes that share domains with NAP1L3: view

No data available for Gene Families for NAP1L3 Gene

Function for NAP1L3 Gene

Molecular function for NAP1L3 Gene

GENATLAS Biochemistry: nucleosome assembly protein-like 3,tightly linked to DXS990

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for NAP1L3 Gene

Localization for NAP1L3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for NAP1L3 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for NAP1L3 Gene COMPARTMENTS Subcellular localization image for NAP1L3 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for NAP1L3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with NAP1L3: view

Pathways for NAP1L3 Gene

SuperPathways for NAP1L3 Gene

No Data Available

Gene Ontology (GO) - Biological Process for NAP1L3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006334 nucleosome assembly IEA --
genes like me logo Genes that share ontologies with NAP1L3: view

No data available for Pathways by source for NAP1L3 Gene

Transcripts for NAP1L3 Gene

mRNA/cDNA for NAP1L3 Gene

Unigene Clusters for NAP1L3 Gene

Nucleosome assembly protein 1-like 3:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for NAP1L3 Gene

No ASD Table

Relevant External Links for NAP1L3 Gene

GeneLoc Exon Structure for
NAP1L3
ECgene alternative splicing isoforms for
NAP1L3

Expression for NAP1L3 Gene

mRNA expression in normal human tissues for NAP1L3 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for NAP1L3 Gene

This gene is overexpressed in Brain - Frontal Cortex (BA9) (6.6), Brain - Anterior cingulate cortex (BA24) (5.6), Brain - Hypothalamus (5.4), and Brain - Cerebellar Hemisphere (5.1).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for NAP1L3 Gene

SOURCE GeneReport for Unigene cluster for NAP1L3 Gene Hs.21365

genes like me logo Genes that share expressions with NAP1L3: view

No data available for mRNA Expression by UniProt/SwissProt for NAP1L3 Gene

Orthologs for NAP1L3 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for NAP1L3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia NAP1L3 35
  • 99.6 (n)
  • 99.21 (a)
NAP1L3 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia NAP1L3 35
  • 82.34 (n)
  • 75.77 (a)
NAP1L3 36
  • 81 (a)
OneToOne
dog
(Canis familiaris)
Mammalia NAP1L3 35
  • 85.59 (n)
  • 80.93 (a)
NAP1L3 36
  • 82 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Nap1l3 35
  • 80.03 (n)
  • 76.19 (a)
Nap1l3 16
Nap1l3 36
  • 73 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 44 (a)
ManyToMany
-- 36
  • 39 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 38 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Nap1l3 35
  • 80.19 (n)
  • 75.35 (a)
chicken
(Gallus gallus)
Aves -- 36
  • 39 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 36 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii nap1l1 36
  • 38 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG3708 36
  • 27 (a)
ManyToMany
CG5017 36
  • 31 (a)
ManyToMany
Nap1 36
  • 31 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea nap-1 36
  • 29 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes NAP1 36
  • 21 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.925 36
  • 32 (a)
OneToMany
Species with no ortholog for NAP1L3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for NAP1L3 Gene

ENSEMBL:
Gene Tree for NAP1L3 (if available)
TreeFam:
Gene Tree for NAP1L3 (if available)

Paralogs for NAP1L3 Gene

Paralogs for NAP1L3 Gene

Selected SIMAP similar genes for NAP1L3 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with NAP1L3: view

Variants for NAP1L3 Gene

Sequence variations from dbSNP and Humsavar for NAP1L3 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs9501 -- 93,671,026(-) TTCCC(C/T)TTCAC utr-variant-3-prime
rs3752336 -- 93,670,840(+) TAGTT(A/C)TCTTT downstream-variant-500B
rs11550945 -- 93,671,036(+) AGGTA(A/G)AACAC utr-variant-3-prime
rs12832717 -- 93,671,242(+) GCTAA(C/T)CTTTT utr-variant-3-prime
rs12861998 -- 93,671,241(+) TGCTA(A/T)TCTTT utr-variant-3-prime

Relevant External Links for NAP1L3 Gene

HapMap Linkage Disequilibrium report
NAP1L3
Locus Specific Mutation Databases (LSDB)
NAP1L3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for NAP1L3 Gene

Disorders for NAP1L3 Gene

No disorders were found for NAP1L3 Gene.

No data available for UniProtKB/Swiss-Prot for NAP1L3 Gene

Publications for NAP1L3 Gene

  1. Cloning, expression pattern and mapping to Xq of NAP1L3, a gene encoding a peptide homologous to human and yeast nucleosome assembly proteins. (PMID: 8976385) Watanabe T.K. … Takahashi E. (Cytogenet. Cell Genet. 1996) 2 3 4 23
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3

Products for NAP1L3 Gene

Sources for NAP1L3 Gene

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