Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



NAP1L2 Gene

protein-coding   GIFtS: 50
GCID: GC0XM072348

Nucleosome Assembly Protein 1-Like 2

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Nucleosome Assembly Protein 1-Like 21 2
BPX2 3 5
Brain-Specific Protein, X-Linked2 3
Brain Specific Gene BPX2

External Ids:    HGNC: 76381   Entrez Gene: 46742   Ensembl: ENSG000001864627   OMIM: 3000265   UniProtKB: Q9ULW63   

Export aliases for NAP1L2 gene to outside databases

Previous GC identifers: GC0XM068245 GC0XM069606 GC0XM070646 GC0XM071298 GC0XM072215 GC0XM066066


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for NAP1L2 Gene:
The protein encoded by this intronless gene is a member of the nucleosome assembly protein (NAP) family. The
encoded protein represents a class of tissue-specific factors that interact with chromatin to regulate neuronal
cell proliferation. (provided by RefSeq, Jan 2011)

GeneCards Summary for NAP1L2 Gene:
NAP1L2 (nucleosome assembly protein 1-like 2) is a protein-coding gene. Diseases associated with NAP1L2 include spina bifida, and neural tube defects. An important paralog of this gene is NAP1L3.

UniProtKB/Swiss-Prot: NP1L2_HUMAN, Q9ULW6
Function: Acidic protein which may be involved in interactions with other proteins or DNA (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000023.11  NC_018934.2  NT_011651.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the NAP1L2 gene promoter:
         Nkx3-1   GATA-3   Pbx1a   POU3F1   CUTL1   C/EBPalpha   GATA-2   GATA-1   AREB6   c-Myb   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNAP1L2 promoter sequence
   Search Chromatin IP Primers for NAP1L2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NAP1L2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq13   Ensembl cytogenetic band:  Xq13.2   HGNC cytogenetic band: Xq13

NAP1L2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NAP1L2 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM072348:  view genomic region     (about GC identifiers)

Start:
72,432,135 bp from pter      End:
72,434,710 bp from pter
Size:
2,576 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: NP1L2_HUMAN, Q9ULW6 (See protein sequence)
Recommended Name: Nucleosome assembly protein 1-like 2  
Size: 460 amino acids; 52542 Da
Secondary accessions: B2RE61 Q8TAN6

Explore the universe of human proteins at neXtProt for NAP1L2: NX_Q9ULW6

Explore proteomics data for NAP1L2 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys267
  • Modification sites at PhosphoSitePlus

  • See NAP1L2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_068798.1  
    ENSEMBL proteins: 
     ENSP00000362616   ENSP00000441555  

    NAP1L2 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for NAP1L2
    OriGene Protein Over-expression Lysate for NAP1L2
    OriGene MassSpec for NAP1L2
    OriGene Custom Protein Services for NAP1L2
    GenScript Custom Purified and Recombinant Proteins Services for NAP1L2
    Novus Biologicals NAP1L2 Proteins
    Novus Biologicals NAP1L2 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    ProSpec Recombinant Protein for NAP1L2
    Cloud-Clone Corp. Proteins for NAP1L2

    NAP1L2 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for NAP1L2
    Novus Biologicals NAP1L2 Antibodies
    Abcam antibodies for NAP1L2
    Cloud-Clone Corp. Antibodies for NAP1L2
    Search ThermoFisher Antibodies for NAP1L2
    LSBio Antibodies in human, mouse, rat for NAP1L2

    NAP1L2 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for NAP1L2
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for NAP1L2
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for NAP1L2
    Cloud-Clone Corp. CLIAs for NAP1L2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    1 InterPro protein domain:
     IPR002164 NAP_family

    Graphical View of Domain Structure for InterPro Entry Q9ULW6

    ProtoNet protein and cluster: Q9ULW6

    1 Blocks protein domain: IPB002164 Nucleosome assembly protein (NAP)

    UniProtKB/Swiss-Prot: NP1L2_HUMAN, Q9ULW6
    Similarity: Belongs to the nucleosome assembly protein (NAP) family


    NAP1L2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NP1L2_HUMAN, Q9ULW6
    Function: Acidic protein which may be involved in interactions with other proteins or DNA (By similarity)

         Genatlas biochemistry entry for NAP1L2:
    nucleosome assembly protein 1-like 2,murine Bpx homolog

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI18985028
         
    NAP1L2 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NAP1L2
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for NAP1L2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NAP1L2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NAP1L2

    miRNA
    Products:
        
    miRTarBase miRNAs that target NAP1L2:
    hsa-mir-142-3p (MIRT021545)

    Block miRNA regulation of human, mouse, rat NAP1L2 using miScript Target Protectors
    6 qRT-PCR Assays for microRNAs that regulate NAP1L2:
    hsa-miR-217 hsa-miR-27a hsa-miR-589* hsa-miR-3662 hsa-miR-3647-3p hsa-miR-27b
    SwitchGear 3'UTR luciferase reporter plasmidNAP1L2 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for NAP1L2
    Predesigned siRNA for gene silencing in human, mouse, rat NAP1L2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for NAP1L2

    Clone
    Products:
         
    OriGene clones in human, mouse for NAP1L2 (see all 7)
    OriGene ORF clones in mouse, rat for NAP1L2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NAP1L2 (NM_021963)
    Sino Biological Human cDNA Clone for NAP1L2
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NAP1L2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NAP1L2

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for NAP1L2
    Browse ESI BIO Cell Lines and PureStem Progenitors for NAP1L2 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NAP1L2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    NP1L2_HUMAN, Q9ULW6: Nucleus (Probable)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus4
    cytosol2
    mitochondrion1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    NAP1L2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus




        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NAP1L2
    Interactions:

        Search GeneGlobe Interaction Network for NAP1L2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for NAP1L2 (Q9ULW62, 3 ENSP000003626164) via UniProtKB, MINT, STRING, and/or I2D (see all 55)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SP110Q9HB583, ENSP000002583814I2D: score=1 STRING: ENSP00000258381
    BAZ1AENSP000003534584STRING: ENSP00000353458
    CHAF1AENSP000003012804STRING: ENSP00000301280
    CHAF1BENSP000003157004STRING: ENSP00000315700
    NAP1L1ENSP000002611824STRING: ENSP00000261182
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006334nucleosome assembly IEA--

    NAP1L2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NAP1L2 (NP1L2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for NAP1L2 gene: 
    NM_021963.3  

    Unigene Cluster for NAP1L2:

    Nucleosome assembly protein 1-like 2
    Hs.66180  [show with all ESTs]
    Unigene Representative Sequence: AK316569
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000373517(uc004ebi.3) ENST00000536638
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat NAP1L2 using miScript Target Protectors
    6 qRT-PCR Assays for microRNAs that regulate NAP1L2:
    hsa-miR-217 hsa-miR-27a hsa-miR-589* hsa-miR-3662 hsa-miR-3647-3p hsa-miR-27b
    SwitchGear 3'UTR luciferase reporter plasmidNAP1L2 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for NAP1L2
    Predesigned siRNA for gene silencing in human, mouse, rat NAP1L2
    Clone
    Products:
         
    OriGene clones in human, mouse for NAP1L2 (see all 7)
    OriGene ORF clones in mouse, rat for NAP1L2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NAP1L2 (NM_021963)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NAP1L2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NAP1L2
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for NAP1L2
    OriGene qSTAR qPCR primer pairs in human, mouse for NAP1L2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NAP1L2
      QuantiTect SYBR Green Assays in human, mouse, rat NAP1L2
      QuantiFast Probe-based Assays in human, mouse, rat NAP1L2

    Additional mRNA sequence: 

    AK316569.1 CR457095.1 

    2 DOTS entries:

    DT.309076  DT.97839188 

    Selected AceView cDNA sequences (see all 45):

    CA771292 AA081879 Z41332 AI350825 AI205064 CA947068 AF136178 CD678482 
    CK826447 CK826446 BQ721589 BM683236 AA634151 NM_021963 F08328 BM719302 
    AB027013 BM725977 AI823491 AA156109 BF448963 CA946795 CA770992 BE466489 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    NAP1L2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAATCACCTC
    NAP1L2 Expression
    About this image


    NAP1L2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Blood (Hematopoietic System)
             Granulocytes Peripheral Blood
    NAP1L2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NAP1L2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.66180
        Custom PCR Arrays for NAP1L2
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for NAP1L2
    OriGene qSTAR qPCR primer pairs in human, mouse for NAP1L2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NAP1L2
    QuantiTect SYBR Green Assays in human, mouse, rat NAP1L2
    QuantiFast Probe-based Assays in human, mouse, rat NAP1L2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NAP1L2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for NAP1L2 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nap1l21 , 5 nucleosome assembly protein 1-like 21, 5 84.53(n)1
    82.79(a)1
      X (45.97 cM)5
    179541  NM_008671.21  NP_032697.21 
     1031841765 
    chicken
    (Gallus gallus)
    Aves --
    Uncharacterized protein
    44(a)
    1 → many
    1(37871087-37885437)
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    41(a)
    1 → many
    5(40559945-40619366)
    zebrafish
    (Danio rerio)
    Actinopterygii nap1l16
    nucleosome assembly protein 1, like 1
    43(a)
    1 → many
    4(2216012-2241310) ENSDARG00000002400
    fruit fly
    (Drosophila melanogaster)
    Insecta Nap16
    CG50176
    (see all 3)
    --
    33(a)
    32(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    2R(19792698-19794837)
    3R(23738169-23739507)
    worm
    (Caenorhabditis elegans)
    Secernentea nap-16
    Protein NAP-1 (nap-1) mRNA, complete cds
    33(a)
    1 → many
    IV(8377705-8379319) WBGene00017075
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes NAP16
    Protein that interacts with mitotic cyclin Clb2p; ...
    25(a)
    1 → many
    XI(525387-526640) YKR048C


    ENSEMBL Gene Tree for NAP1L2 (if available)
    TreeFam Gene Tree for NAP1L2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for NAP1L2 gene
    NAP1L32  NAP1L62  NAP1L42  NAP1L12  
    4 SIMAP similar genes for NAP1L2 using alignment to 3 protein entries:     NP1L2_HUMAN (see all proteins):
    NAP1L6    NAP1L4    NAP1L1    NAP1L5

    NAP1L2 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for NAP1L2
    PGOHUM00000259279


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for NAP1L2 (see all 85)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1436813071,2
    --72439811(+) TTCCTG/TAATCA 1 -- ds50010--------
    rs1806937651,2
    --72439846(+) ACAATC/TAGTAA 1 -- ds50010--------
    rs1850795981,2
    --72439873(+) TCCAGA/GTGACA 1 -- ds50010--------
    rs1895463331,2
    --72439887(+) TGGAAA/GGGTAG 1 -- ds50010--------
    rs1817181091,2
    --72439922(+) ACACAC/GAGGAA 1 -- ds50010--------
    rs1860110401,2
    --72440078(+) GGTATA/GCTTTC 1 -- ds50010--------
    rs1457221841,2
    --72440351(+) GAACAC/TGAAAT 1 -- ut310--------
    rs157381,2
    C--72440387(+) ACTTTC/TAATGA 1 -- ut311Minor allele frequency- T:0.00NA 2
    rs1905280851,2
    --72440563(+) GAGCCA/TATGAA 1 -- ut310--------
    rs1819737831,2
    --72440660(+) TGCATG/TGTTAT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for NAP1L2 (72432135 - 72434710 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for NAP1L2: --
    Locus Specific Mutation Databases (LSDB): NAP1L2

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NAP1L2
    DNA2.0 Custom Variant and Variant Library Synthesis for NAP1L2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 300026    OMIM disorders: --

    3 diseases for NAP1L2:    
    About MalaCards
    spina bifida    neural tube defects    neuronitis


    NAP1L2 for disorders           About GeneDecksing


    Export disorders for NAP1L2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for NAP1L2 gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with NAP1L2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. Cloning and characterization of a murine brain specific gene Bpx and its human homologue lying within the Xic candidate region. (PubMed id 8789438)1, 3 Rougeulle C. and Avner P. (Hum. Mol. Genet. 1996)
    3. Control of neurulation by the nucleosome assembly protein-1-like 2. (PubMed id 10932189)1, 9 Rogner U.C....Avner P. (Nat. Genet. 2000)
    4. Interaction between nucleosome assembly protein 1-like family members. (PubMed id 21333655)1 Attia M....Rogner U.C. (J. Mol. Biol. 2011)
    5. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    6. A data set of human endogenous protein ubiquitination sites. (PubMed id 20972266)1 Shi Y....Qin J. (amp 2011)
    7. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    8. An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142)1 Ravasi T....Hayashizaki Y. (Cell 2010)
    9. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (Cell 2010)
    10. Hepatitis C virus infection protein network. (PubMed id 18985028)1 de Chassey B....Lotteau V. (Mol. Syst. Biol. 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 4674 HGNC: 7638 AceView: NAP1L2 Ensembl:ENSG00000186462 euGenes: HUgn4674
    ECgene: NAP1L2 H-InvDB: NAP1L2

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for NAP1L2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for NAP1L2 gene:
    Search GeneIP for patents involving NAP1L2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for NAP1L2  
     OriGene qPCR primer pairs and template standards for NAP1L2   OriGene Protein Over-expression Lysate for NAP1L2  
     OriGene MassSpec something-or-other for NAP1L2   OriGene clones in human, mouse for NAP1L2  
     OriGene qSTAR qPCR primer pairs in human, mouse for NAP1L2   OriGene Purified Protein for NAP1L2  
     OriGene ORF clones in mouse, rat for NAP1L2   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for NAP1L2   OriGene Custom Protein Services for NAP1L2  

     
     
     Block miRNA regulation of human, mouse, rat NAP1L2 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing NAP1L2
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NAP1L2 Predesigned siRNA for gene silencing in human, mouse, rat NAP1L2
     QuantiFast Probe-based Assays in human, mouse, rat NAP1L2 QuantiTect SYBR Green Assays in human, mouse, rat NAP1L2
     Custom PCR Arrays for NAP1L2 Search Chromatin IP Primers for NAP1L2
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NAP1L2  Search GeneGlobe Interaction Network for NAP1L2
     Regulatory tfbs in NAP1L2 promoter
     GenScript Custom Purified and Recombinant Proteins Services for NAP1L2 GenScript cDNA clones with any tag delivered in your preferred vector for NAP1L2
     GenScript Custom Assay Services for NAP1L2 GenScript Custom overexpressing Cell Line Services for NAP1L2
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for NAP1L2 (NP1L2)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     cDNA Clones for NAP1L2
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     NAP1L2 antibodies
     NAP1L2 proteins
     NAP1L2 lysates
     Antibodies for NAP1L2
     See all of Abcam's Antibodies, Kits and Proteins for NAP1L2
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Recombinant Protein for NAP1L2
     Proteins for NAP1L2
     Antibodies for NAP1L2
     ELISAs for NAP1L2
     CLIAs for NAP1L2



     Browse ESI BIO Cell Lines and PureStem Progenitors for NAP1L2
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NAP1L2
     SwitchGear 3'UTR luciferase reporter plasmids for NAP1L2
     SwitchGear Promoter luciferase reporter plasmids for NAP1L2
     Search ThermoFisher Antibodies for NAP1L2
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NAP1L2
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NAP1L2
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for NAP1L2
     LSBio Antibodies in human, mouse, rat for NAP1L2
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      NAP1L2 gene at Home site.
    Version: 3.12.142 28 July 2014
    hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4